The emerging role of microRNAs in schizophrenia and autism spectrum disorders

Untitled work

Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714 · see citing works

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993) · Cell · doi:10.1016/0092-8674(93)90529-y · Cited by 12,948 · see citing works

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Valadi, H., Ekström, K., Bossios, A., Sjöstrand, M., Lee, J. J., & Lötvall, J. O. (2007) · Nature Cell Biology · doi:10.1038/ncb1596 · Cited by 12,834 · see citing works

The widespread regulation of microRNA biogenesis, function and decay

Krol, J., Loedige, I., & Filipowicz, W. (2010) · Nature Reviews Genetics · doi:10.1038/nrg2843 · Cited by 4,672 · see citing works

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

Chen, X., Ba, Y., Ma, L., Cai, X., Yin, Y., Wang, K., Guo, J., Zhang, Y., Chen, J., Guo, X., et al. (2008) · Cell Research · doi:10.1038/cr.2008.282 · Cited by 4,560 · see citing works

NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

Taganov, K. D., Boldin, M. P., Chang, K.-J., & Baltimore, D. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0605298103 · Cited by 4,317 · see citing works

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

Wightman, B., Ha, I., & Ruvkun, G. (1993) · Cell · doi:10.1016/0092-8674(93)90530-4 · Cited by 4,292 · see citing works

Genome-wide association study identifies five new schizophrenia loci

The Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium (2011) · Nature Genetics · doi:10.1038/ng.940 · Cited by 1,919 · see citing works

A brain-specific microRNA regulates dendritic spine development

Schratt, G. M., Tuebing, F., Nigh, E. A., Kane, C. G., Sabatini, M. E., Kiebler, M., & Greenberg, M. E. (2006) · Nature · doi:10.1038/nature04367 · Cited by 1,786 · see citing works

The emerging mechanisms of isoform-specific PI3K signalling

Vanhaesebroeck, B., Guillermet-Guibert, J., Graupera, M., & Bilanges, B. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2882 · Cited by 1,767 · see citing works

Decreased Dendritic Spine Density on Prefrontal Cortical Pyramidal Neurons in Schizophrenia

Glantz, L. A., & Lewis, D. A. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.1.65 · Cited by 1,636 · see citing works

Dendritic spine pathology in neuropsychiatric disorders

Penzes, P., Cahill, M. E., Jones, K. A., VanLeeuwen, J.-E., & Woolfrey, K. M. (2011) · Nature Neuroscience · doi:10.1038/nn.2741 · Cited by 1,523 · see citing works

The MicroRNA miR-124 Promotes Neuronal Differentiation by Triggering Brain-Specific Alternative Pre-mRNA Splicing

Makeyev, E. V., Zhang, J., Carrasco, M. A., & Maniatis, T. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.07.015 · Cited by 1,395 · see citing works

Decrease in Reelin and Glutamic Acid Decarboxylase67 (GAD67) Expression in Schizophrenia and Bipolar Disorder

Guidotti, A., Auta, J., Davis, J. M., Gerevini, V. D. G., Dwivedi, Y., Grayson, D. R., Impagnatiello, F., Pandey, G. N., Pesold, C., Sharma, R. P., et al. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.11.1061 · Cited by 1,203 · see citing works

Repression of protein synthesis by miRNAs: how many mechanisms?

Pillai, R. S., Bhattacharyya, S. N., & Filipowicz, W. (2007) · Trends in Cell Biology · doi:10.1016/j.tcb.2006.12.007 · Cited by 1,109 · see citing works

High rates of schizophrenia in adults with velo-cardio-facial syndrome

Murphy, K. C., Jones, L. A., & Owen, M. J. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.10.940 · Cited by 1,024 · see citing works

Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics.

Akbarian, S. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950160008002 · Cited by 1,002 · see citing works

Involvement of Human Micro-RNA in Growth and Response to Chemotherapy in Human Cholangiocarcinoma Cell Lines

Meng, F., Henson, R., Lang, M., Wehbe, H., Maheshwari, S., Mendell, J. T., Jiang, J., Schmittgen, T. D., & Patel, T. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.02.057 · Cited by 984 · see citing works

A novel pathway regulates memory and plasticity via SIRT1 and miR-134

Gao, J., Wang, W.-Y., Mao, Y.-W., Gräff, J., Guan, J.-S., Pan, L., Mak, G., Kim, D., Su, S. C., & Tsai, L.-H. (2010) · Nature · doi:10.1038/nature09271 · Cited by 975 · see citing works

Sequence Variants in <i>SLITRK1</i> Are Associated with Tourette's Syndrome

Abelson, J. F., Kwan, K. Y., O'Roak, B. J., Baek, D. Y., Stillman, A. A., Morgan, T. M., Mathews, C. A., Pauls, D. L., Rašin, M.-R., Gunel, M., et al. (2005) · Science · doi:10.1126/science.1116502 · Cited by 940 · see citing works

Exosomes are released by cultured cortical neurones

Fauré, J., Lachenal, G., Court, M., Hirrlinger, J., Chatellard-Causse, C., Blot, B., Grange, J., Schoehn, G., Goldberg, Y., Boyer, V., et al. (2006) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2005.12.003 · Cited by 896 · see citing works

STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

Iliopoulos, D., Jaeger, S. A., Hirsch, H. A., Bulyk, M. L., & Struhl, K. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.07.023 · Cited by 830 · see citing works

A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis

Vo, N., Klein, M. E., Varlamova, O., Keller, D. M., Yamamoto, T. S., Goodman, R. H., & Impey, S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508448102 · Cited by 799 · see citing works

MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway

Ponomarev, E. D., Veremeyko, T., Barteneva, N., Krichevsky, A. M., & Weiner, H. L. (2011) · Nature Medicine · doi:10.1038/nm.2266 · Cited by 787 · see citing works

Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders

Hutsler, J. J., & Zhang, H. (2010) · Brain Research · doi:10.1016/j.brainres.2009.09.120 · Cited by 765 · see citing works

Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

Edbauer, D., Neilson, J. R., Foster, K. A., Wang, C.-F., Seeburg, D. P., Batterton, M. N., Tada, T., Dolan, B. M., Sharp, P. A., & Sheng, M. (2010) · Neuron · doi:10.1016/j.neuron.2010.01.005 · Cited by 735 · see citing works

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

Stark, K. L., Xu, B., Bagchi, A., Lai, W.-S., Liu, H., Hsu, R., Wan, X., Pavlidis, P., Mills, A. A., Karayiorgou, M., et al. (2008) · Nature Genetics · doi:10.1038/ng.138 · Cited by 648 · see citing works

The role of immune dysfunction in the pathophysiology of autism

Onore, C., Careaga, M., & Ashwood, P. (2012) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2011.08.007 · Cited by 635 · see citing works

microRNA Modulation of Circadian-Clock Period and Entrainment

Cheng, H. M., Papp, J. W., Varlamova, O., Dziema, H., Russell, B. S., Curfman, J. P., Nakazawa, T., Shimizu, K., Okamura, H., Impey, S., et al. (2007) · Neuron · doi:10.1016/j.neuron.2007.05.017 · Cited by 589 · see citing works

The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development

Visvanathan, J., Lee, S., Lee, B., Lee, J. W., & Lee, S.-K. (2007) · Genes &amp; Development · doi:10.1101/gad.1519107 · Cited by 579 · see citing works

An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP

Wayman, G. A., Davare, M., Ando, H., Fortin, D., Varlamova, O., Cheng, H.-Y. M., Marks, D., Obrietan, K., Soderling, T. R., Goodman, R. H., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803072105 · Cited by 559 · see citing works

Dicer1 and miR-219 Are Required for Normal Oligodendrocyte Differentiation and Myelination

Dugas, J. C., Cuellar, T. L., Scholze, A., Ason, B., Ibrahim, A., Emery, B., Zamanian, J. L., Foo, L. C., McManus, M. T., & Barres, B. A. (2010) · Neuron · doi:10.1016/j.neuron.2010.01.027 · Cited by 527 · see citing works

Cross talk between microRNA and epigenetic regulation in adult neurogenesis

Szulwach, K. E., Li, X., Smrt, R. D., Li, Y., Luo, Y., Lin, L., Santistevan, N. J., Li, W., Zhao, X., & Jin, P. (2010) · Journal of Cell Biology · doi:10.1083/jcb.200908151 · Cited by 493 · see citing works

Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia

Hashimoto, T., Arion, D., Unger, T., Maldonado-Avilés, J. G., Morris, H. M., Volk, D. W., Mirnics, K., & Lewis, D. A. (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002011 · Cited by 490 · see citing works

Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions

Ambasudhan, R., Talantova, M. V., Coleman, R., Xu, Y., Zhu, S., Lipton, S. A., & Ding, S. (2011) · Cell stem cell · doi:10.1016/j.stem.2011.07.002 · Cited by 480 · see citing works

microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder

Perkins, D. O., Jeffries, C. D., Jarskog, L. F., Thomson, J. M., Woods, K., Newman, M. A., Parker, J. S., Jin, J., & Hammond, S. M. (2007) · Genome Biology · doi:10.1186/gb-2007-8-2-r27 · Cited by 479 · see citing works

Characterizing Light-Regulated Retinal MicroRNAs Reveals Rapid Turnover as a Common Property of Neuronal MicroRNAs

Krol, J., Busskamp, V., Markiewicz, I., Stadler, M. B., Ribi, S., Richter, J., Duebel, J., Bicker, S., Fehling, H. J., Schübeler, D., et al. (2010) · Cell · doi:10.1016/j.cell.2010.03.039 · Cited by 470 · see citing works

Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA

Klein, M. E., Lioy, D. T., Ma, L., Impey, S., Mandel, G., & Goodman, R. H. (2007) · Nature Neuroscience · doi:10.1038/nn2010 · Cited by 444 · see citing works

MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212

Im, H., Hollander, J. A., Bali, P., & Kenny, P. J. (2010) · Nature Neuroscience · doi:10.1038/nn.2615 · Cited by 435 · see citing works

Schizophrenia is associated with an increase in cortical microRNA biogenesis

Beveridge, N. J., Gardiner, E. J., Carroll, A. P., Tooney, P. A., & Cairns, M. J. (2009) · Molecular Psychiatry · doi:10.1038/mp.2009.84 · Cited by 431 · see citing works

microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus

Magill, S. T., Cambronne, X. A., Luikart, B. W., Lioy, D. T., Leighton, B. H., Westbrook, G. L., Mandel, G., & Goodman, R. H. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015691107 · Cited by 431 · see citing works

A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis

Siegel, G., Obernosterer, G., Fiore, R., Oehmen, M., Bicker, S., Christensen, M., Khudayberdiev, S., Leuschner, P. F., Busch, C. J. L., Kane, C., et al. (2009) · Nature Cell Biology · doi:10.1038/ncb1876 · Cited by 427 · see citing works

MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase

Shaked, I., Meerson, A., Wolf, Y., Avni, R., Greenberg, D., Gilboa-Geffen, A., & Soreq, H. (2009) · Immunity · doi:10.1016/j.immuni.2009.09.019 · Cited by 416 · see citing works

Characterization of Small RNAs in Aplysia Reveals a Role for miR-124 in Constraining Synaptic Plasticity through CREB

Rajasethupathy, P., Fiumara, F., Sheridan, R., Betel, D., Puthanveettil, S. V., Russo, J. J., Sander, C., Tuschl, T., & Kandel, E. (2009) · Neuron · doi:10.1016/j.neuron.2009.05.029 · Cited by 406 · see citing works

MicroRNA miR-137 Regulates Neuronal Maturation by Targeting Ubiquitin Ligase Mind Bomb-1

Smrt, R. D., Szulwach, K. E., Pfeiffer, R. L., Li, X., Guo, W., Pathania, M., Teng, Z.-Q., Luo, Y., Peng, J., Bordey, A., et al. (2010) · Stem Cells · doi:10.1002/stem.431 · Cited by 404 · see citing works

Loss of miR-200 Inhibition of Suz12 Leads to Polycomb-Mediated Repression Required for the Formation and Maintenance of Cancer Stem Cells

Iliopoulos, D., Lindahl-Allen, M., Polytarchou, C., Hirsch, H. A., Tsichlis, P. N., & Struhl, K. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.08.013 · Cited by 399 · see citing works

Striatal microRNA controls cocaine intake through CREB signalling

Hollander, J. A., Im, H., Amelio, A. L., Kocerha, J., Bali, P., Lu, Q., Willoughby, D., Wahlestedt, C., Conkright, M. D., & Kenny, P. J. (2010) · Nature · doi:10.1038/nature09202 · Cited by 387 · see citing works

Conditional Loss of Dicer Disrupts Cellular and Tissue Morphogenesis in the Cortex and Hippocampus

Davis, T. H., Cuellar, T. L., Koch, S. M., Barker, A. J., Harfe, B. D., McManus, M. T., & Ullian, E. M. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4815-07.2008 · Cited by 384 · see citing works

miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional co-activator

Lagos, D., Pollara, G., Henderson, S. R., Gratrix, F., Fabani, M. M., Milne, R. S. B., Gotch, F. M., & Boshoff, C. (2010) · Nature Cell Biology · doi:10.1038/ncb2054 · Cited by 339 · see citing works

Dysregulation of miRNA 181b in the temporal cortex in schizophrenia

Beveridge, N. J., Tooney, P. A., Carroll, A. P., Gardiner, E. J., Bowden, N. A., Scott, R. J., Tran, N., Dedova, I. V., & Cairns, M. J. (2008) · Human Molecular Genetics · doi:10.1093/hmg/ddn005 · Cited by 328 · see citing works

Analysis of MiR-195 and MiR-497 Expression, Regulation and Role in Breast Cancer

Li, D., Zhao, Y., Liu, C., Chen, X., Qi, Y., Jiang, Y., Zou, C., Zhang, X., Liu, S., Wang, X., et al. (2011) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-10-1800 · Cited by 318 · see citing works

MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation

Yu, J., Chung, K.-H., Deo, M., Thompson, R. C., & Turner, D. L. (2008) · Experimental Cell Research · doi:10.1016/j.yexcr.2008.06.002 · Cited by 310 · see citing works

MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function

Miller, B. H., Zeier, Z., Xi, L., Lanz, T. A., Deng, S., Strathmann, J., Willoughby, D., Kenny, P. J., Elsworth, J. D., Lawrence, M. S., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1113793109 · Cited by 309 · see citing works

miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells

Sun, G., Ye, P., Murai, K., Lang, M., Li, S., Zhang, H., Li, W., Fu, C., Yin, J., Wang, A., et al. (2011) · Nature Communications · doi:10.1038/ncomms1532 · Cited by 306 · see citing works

Neuronal activity rapidly induces transcription of the CREB‐regulated microRNA‐132, in vivo

Nudelman, A. S., DiRocco, D. P., Lambert, T. J., Garelick, M. G., Le, J. H., Nathanson, N. M., & Storm, D. R. (2009) · Hippocampus · doi:10.1002/hipo.20646 · Cited by 300 · see citing works

MicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders

Kim, A. H., Reimers, M., Maher, B., Williamson, V., McMichael, O., McClay, J. L., van den Oord, E. J. C. G., Riley, B. P., Kendler, K. S., & Vladimirov, V. I. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2010.07.002 · Cited by 298 · see citing works

The prevalence of PTEN mutations in a clinical pediatric cohort with autism spectrum disorders, developmental delay, and macrocephaly

Varga, E. A., Pastore, M., Prior, T. W., Herman, G. E., & McBride, K. L. (2009) · Genetics in Medicine · doi:10.1097/gim.0b013e31818fd762 · Cited by 293 · see citing works

MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction

Kocerha, J., Faghihi, M. A., López-Toledano, M. A., Huang, J., Ramsey, A. J., Caron, M. G., Salès, N., Willoughby, D., Elmén, J., Hansen, H. F., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0805854106 · Cited by 292 · see citing works

Stem Cell Quiescence

Li, L., & Bhatia, R. (2011) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-10-1499 · Cited by 291 · see citing works

Reduced Dendritic Spine Density in Auditory Cortex of Subjects with Schizophrenia

Sweet, R. A., Henteleff, R. A., Zhang, W., Sampson, A. R., & Lewis, D. A. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2008.67 · Cited by 290 · see citing works

Cell-Type-Based Analysis of MicroRNA Profiles in the Mouse Brain

He, M., Liu, Y., Wang, X., Zhang, M. Q., Hannon, G. J., & Huang, Z. J. (2012) · Neuron · doi:10.1016/j.neuron.2011.11.010 · Cited by 277 · see citing works

TRPC channels are necessary mediators of pathologic cardiac hypertrophy

Wu, X., Eder, P., Chang, B., & Molkentin, J. D. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1001825107 · Cited by 273 · see citing works

Heterogeneous dysregulation of microRNAs across the autism spectrum

Abu-Elneel, K., Liu, T., Gazzaniga, F. S., Nishimura, Y., Wall, D. P., Geschwind, D. H., Lao, K., & Kosik, K. S. (2008) · neurogenetics · doi:10.1007/s10048-008-0133-5 · Cited by 271 · see citing works

An activity-induced microRNA controls dendritic spine formation by regulating Rac1-PAK signaling

Impey, S., Davare, M., Lasiek, A., Fortin, D., Ando, H., Varlamova, O., Obrietan, K., Soderling, T. R., Goodman, R. H., & Wayman, G. A. (2010) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2009.10.005 · Cited by 270 · see citing works

MicroRNA Loss Enhances Learning and Memory in Mice

Konopka, W., Kiryk, A., Novak, M., Herwerth, M., Parkitna, J. R., Wawrzyniak, M., Kowarsch, A., Michaluk, P., Dzwonek, J., Arnsperger, T., et al. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.3030-10.2010 · Cited by 268 · see citing works

Molecular Determinants of Dysregulated GABAergic Gene Expression in the Prefrontal Cortex of Subjects with Schizophrenia

Mellios, N., Huang, H.-S., Baker, S. P., Galdzicka, M., Ginns, E., & Akbarian, S. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.11.019 · Cited by 266 · see citing works

Brain Expressed microRNAs Implicated in Schizophrenia Etiology

Hansen, T. F., Olsen, L., Lindow, M., Jakobsen, K. D., Ullum, H., Jönsson, E. G., Andreassen, O. A., Djurovic, S., Melle, I. S., Agartz, I., et al. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000873 · Cited by 259 · see citing works

Upregulation of Dicer and MicroRNA Expression in the Dorsolateral Prefrontal Cortex Brodmann Area 46 in Schizophrenia

Santarelli, D. M., Beveridge, N. J., Tooney, P. A., & Cairns, M. J. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.09.030 · Cited by 255 · see citing works

Exosomal transfer of proteins and RNAs at synapses in the nervous system

Smalheiser, N. R. (2007) · Biology Direct · doi:10.1186/1745-6150-2-35 · Cited by 251 · see citing works

Altered MicroRNA Expression Profiles in Postmortem Brain Samples from Individuals with Schizophrenia and Bipolar Disorder

Moreau, M. P., Bruse, S. E., David-Rus, R., Buyske, S., & Brzustowicz, L. M. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.09.039 · Cited by 249 · see citing works

A set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortex

Mellios, N., Huang, H.-S., Grigorenko, A., Rogaev, E., & Akbarian, S. (2008) · Human Molecular Genetics · doi:10.1093/hmg/ddn201 · Cited by 239 · see citing works

Imprinted DLK1-DIO3 region of 14q32 defines a schizophrenia-associated miRNA signature in peripheral blood mononuclear cells

Gardiner, E. J., Beveridge, N. J., Wu, J. Q., Carr, V. J., Scott, R. J., Tooney, P. A., & Cairns, M. J. (2011) · Molecular Psychiatry · doi:10.1038/mp.2011.78 · Cited by 232 · see citing works

Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines

Sarachana, T., Zhou, R., Chen, G., Manji, H. K., & Hu, V. W. (2010) · Genome Medicine · doi:10.1186/gm144 · Cited by 229 · see citing works

MicroRNA Expression Aberration as Potential Peripheral Blood Biomarkers for Schizophrenia

Lai, C.-Y., Yu, S.-L., Hsieh, M. H., Chen, C.-H., Chen, H.-Y., Wen, C.-C., Huang, Y.-H., Hsiao, P.-C., Hsiao, C. K., Liu, C.-M., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021635 · Cited by 228 · see citing works

Transgenic miR132 Alters Neuronal Spine Density and Impairs Novel Object Recognition Memory

Hansen, K. F., Sakamoto, K., Wayman, G. A., Impey, S., & Obrietan, K. H. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015497 · Cited by 225 · see citing works

Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration

Cuellar, T. L., Davis, T. H., Nelson, P. T., Loeb, G. B., Harfe, B. D., Ullian, E. M., & McManus, M. T. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801689105 · Cited by 220 · see citing works

Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins

Reményi, J., Hunter, C. J., Cole, C., Ando, H., Impey, S., Monk, C. E., Martin, K. J., Barton, G. J., Hutvágner, G., & Arthur, J. S. C. (2010) · Biochemical Journal · doi:10.1042/bj20100024 · Cited by 215 · see citing works

Dicer ablation in oligodendrocytes provokes neuronal impairment in mice

Shin, D., Shin, J., McManus, M. T., Ptáček, L. J., & Fu, Y. (2009) · Annals of Neurology · doi:10.1002/ana.21927 · Cited by 207 · see citing works

Deficiency of <i>Dgcr8</i> , a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex

Fénelon, K., Mukai, J., Xu, B., Hsu, P.-K., Drew, L. J., Karayiorgou, M., Fischbach, G. D., MacDermott, A. B., & Gogos, J. A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1101219108 · Cited by 202 · see citing works

The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory

Lin, Q., Wei, W., Coelho, C. M., Li, X., Baker-Andresen, D., Dudley, K., Ratnu, V. S., Boskovic, Z., Kobor, M. S., Sun, Y. E., et al. (2011) · Nature Neuroscience · doi:10.1038/nn.2891 · Cited by 200 · see citing works

MicroRNA-134 plasma levels before and after treatment for bipolar mania

Rong, H., Liu, T. B., Yang, K. J., Yang, H. C., Wu, D., Liao, C.-P., Hong, F., Yang, H. Z., Wan, F., Ye, X. Y., et al. (2010) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2010.04.028 · Cited by 189 · see citing works

Roles of small regulatory RNAs in determining neuronal identity

Li, X., & Jin, P. (2010) · Nature reviews. Neuroscience · doi:10.1038/nrn2739 · Cited by 180 · see citing works

Genome-wide analysis reveals methyl-CpG–binding protein 2–dependent regulation of microRNAs in a mouse model of Rett syndrome

Wu, H., Tao, J., Chen, P. J., Shahab, A., Ge, W., Hart, R. P., Ruan, X., Ruan, Y., & Sun, Y. E. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1005595107 · Cited by 180 · see citing works

Gene and miRNA expression profiles in autism spectrum disorders

Seno, M. M. G., Hu, P., Gwadry, F. G., Pinto, D., Marshall, C. R., Casallo, G., & Scherer, S. W. (2010) · Brain Research · doi:10.1016/j.brainres.2010.09.046 · Cited by 175 · see citing works

miR-23regulation of lamin B1 is crucial for oligodendrocyte development and myelination

Lin, S., & Fu, Y. (2009) · Disease Models & Mechanisms · doi:10.1242/dmm.001065 · Cited by 169 · see citing works

Human Cytomegalovirus Infection Alters the Expression of Cellular MicroRNA Species That Affect Its Replication

Wang, F.-Z., Weber, F., Croce, C. M., Liu, C., Liao, X., & Pellett, P. E. (2008) · Journal of Virology · doi:10.1128/jvi.00961-08 · Cited by 166 · see citing works

Deletion of Astroglial Dicer Causes Non-Cell-Autonomous Neuronal Dysfunction and Degeneration

Tao, J., Wu, H., Lin, Q., Wei, W., Lu, X., Cantle, J. P., Ao, Y., Olsen, R. W., Yang, X. W., Módy, I., et al. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.0567-11.2011 · Cited by 166 · see citing works

miR-132, an experience-dependent microRNA, is essential for visual cortex plasticity

Mellios, N., Sugihara, H., Castro, J., Banerjee, A., Le, C., Kumar, A., Crawford, B., Strathmann, J., Tropea, D., Levine, S. S., et al. (2011) · Nature Neuroscience · doi:10.1038/nn.2909 · Cited by 161 · see citing works

A Novel microRNA and transcription factor mediated regulatory network in schizophrenia

Guo, A. Y., Sun, J., Jia, P., & Zhao, Z. (2010) · BMC Systems Biology · doi:10.1186/1752-0509-4-10 · Cited by 160 · see citing works

Feasibility and relevance of examining lymphoblastoid cell lines to study role of microRNAs in autism

Talebizadeh, Z., Butler, M. G., & Theodoro, M. F. (2008) · Autism Research · doi:10.1002/aur.33 · Cited by 157 · see citing works

Functions of Noncoding RNAs in Neural Development and Neurological Diseases

Bian, S., & Sun, T. (2011) · Molecular Neurobiology · doi:10.1007/s12035-011-8211-3 · Cited by 152 · see citing works

Ultrastructural alterations in hippocampal mossy fiber synapses in schizophrenia: A postmortem morphometric study

Kolomeets, N. S., Orlovskaya, D. D., Rachmanova, V. I., & Uranova, N. A. (2005) · Synapse · doi:10.1002/syn.20153 · Cited by 149 · see citing works

Downregulation of miR-132 by promoter methylation contributes to pancreatic cancer development

Zhang, S., Hao, J., Xie, F., Hu, X., Liu, C., Tong, J., Zhou, J., Wu, J., & Shao, C. (2011) · Carcinogenesis · doi:10.1093/carcin/bgr105 · Cited by 148 · see citing works

Aberrant expression of serum miRNAs in schizophrenia

Shi, W., Du, J., Qi, Y., Liang, G., Wang, T., Li, S., Xie, S., Zeshan, B., & Xiao, Z. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.09.010 · Cited by 143 · see citing works

Collagen VI protects neurons against Aβ toxicity

Cheng, J. S., Dubal, D. B., Kim, D. H., Legleiter, J. A., Cheng, I. H.-J., Yu, G.-Q., Tesseur, I. C., Wyss‐Coray, T., Bonaldo, P., & Mucke, L. (2009) · Nature Neuroscience · doi:10.1038/nn.2240 · Cited by 138 · see citing works

Development of Patient-Specific Neurons in Schizophrenia Using Induced Pluripotent Stem Cells

Pedrosa, E., Sandler, V. M., Shah, A., Carroll, R. C., Chang, C.-J., Rockowitz, S., Guo, X., Zheng, D., & Lachman, H. M. (2011) · Journal of Neurogenetics · doi:10.3109/01677063.2011.597908 · Cited by 129 · see citing works

miR-132 Mediates the Integration of Newborn Neurons into the Adult Dentate Gyrus

Luikart, B. W., Bensen, A. L., Washburn, E. K., Perederiy, J. V., Su, K. G., Li, Y., Kernie, S. G., Parada, L. F., & Westbrook, G. L. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019077 · Cited by 125 · see citing works

Fragile X syndrome: from molecular genetics to therapy

D’Hulst, C., & Kooy, R. F. (2009) · Journal of Medical Genetics · doi:10.1136/jmg.2008.064667 · Cited by 125 · see citing works

A MicroRNA gene is hosted in an intron of a schizophrenia-susceptibility gene

Zhu, Y., Kalbfleisch, T., Brennan, M. D., & Li, Y. (2009) · Schizophrenia Research · doi:10.1016/j.schres.2009.01.022 · Cited by 113 · see citing works

Experience-dependent expression of miR-132 regulates ocular dominance plasticity

Tognini, P., Putignano, E., Coatti, A., & Pizzorusso, T. (2011) · Nature Neuroscience · doi:10.1038/nn.2920 · Cited by 108 · see citing works

Autism and congenital cytomegalovirus

Stubbs, E. G., Ash, E., & Williams, C. P. S. (1984) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02409660 · Cited by 104 · see citing works

Circadian rhythms and clock genes in psychotic disorders.

Lamont, E. W., Coutu, D. L., Cermakian, N., & Boivin, D. B. (2010) · PubMed · Cited by 102 · see citing works

MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia

Xu, Y. J., Li, F., Zhang, B., Zhang, K., Zhang, F., Huang, X., Sun, N., Ren, Y., Sui, M., & Liu, P. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2010.02.1070 · Cited by 93 · see citing works

Monoallelic deletion of the microRNA biogenesis gene Dgcr8 produces deficits in the development of excitatory synaptic transmission in the prefrontal cortex

Schofield, C. M., Hsu, R., Barker, A. J., Gertz, C. C., Blelloch, R. H., & Ullian, E. M. (2011) · Neural Development · doi:10.1186/1749-8104-6-11 · Cited by 86 · see citing works

Species-specific microRNA roles elucidated following astrocyte activation

Mor, E., Cabilly, Y., Goldshmit, Y., Zalts, H., Modai, S., Edry, L., Elroy‐Stein, O., & Shomron, N. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkq1325 · Cited by 85 · see citing works

Gender-Specific Reduction of Estrogen-Sensitive Small RNA, miR-30b, in Subjects With Schizophrenia

Mellios, N., Galdzicka, M. M., Ginns, E. I., Baker, S. P., Rogaev, E. I., Xu, J., & Akbarian, S. (2010) · Schizophrenia Bulletin · doi:10.1093/schbul/sbq091 · Cited by 75 · see citing works

Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene

Zhang, L., Qing Lan, B., Guo, W., Hubbard, A., Li, G., Rappaport, S. M., McHale, C. M., Shen, M., Ji, Z., Vermeulen, R. C. H., et al. (2011) · Carcinogenesis · doi:10.1093/carcin/bgq286 · Cited by 60 · see citing works

Zfp423/OAZ Participates in a Developmental Switch during Olfactory Neurogenesis

Cheng, L. E., & Reed, R. R. (2007) · Neuron · doi:10.1016/j.neuron.2007.04.029 · Cited by 59 · see citing works

Epigenetics of Schizophrenia

Akbarian, S. (2010) · Current topics in behavioral neurosciences · doi:10.1007/7854_2010_38 · Cited by 57 · see citing works

In sickness and in health: the role of methyl-CpG binding protein 2 in the central nervous system

de León‐Guerrero, S. D., Pedraza‐Alva, G., & Pérez‐Martínez, L. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07658.x · Cited by 52 · see citing works

Schizophrenia and chromosomal deletions within 22q11.2.

Lindsay, E. A., Morris, M. A., Gos, A., Nestadt, G., Wolyniec, P. S., Lasseter, V. K., Shprintzen, R. J., Antonarakis, S. E., Baldini, A., & Pulver, A. E. (1995) · PubMed Central · Cited by 52 · see citing works

Growth factors stimulate expression of neuronal and glial miR-132

Numakawa, T., Yamamoto, N., Chiba, S., Richards, M., Ooshima, Y., Kishi, S., Hashido, K., Adachi, N., & Kunugi, H. (2011) · Neuroscience Letters · doi:10.1016/j.neulet.2011.10.025 · Cited by 43 · see citing works

The F-Like Protein Ac23 Enhances the Infectivity of the Budded Virus of gp64 -Null Autographa californica Multinucleocapsid Nucleopolyhedrovirus Pseudotyped with Baculovirus Envelope Fusion Protein F

Wang, M., Tan, Y., Yin, F., et al. (2008) · Journal of Virology · doi:10.1128/jvi.00759-08 · Cited by 41 · see citing works

The matrix protein CCN1 (CYR61) promotes proliferation, migration and tube formation of endothelial progenitor cells

YU, Y., GAO, Y., WANG, H., Huang, L. J., Qin, J., Guo, R., SONG, M., YU, S., CHEN, J., & CUI, B. (2008) · Experimental Cell Research · doi:10.1016/j.yexcr.2008.08.001 · Cited by 37 · see citing works

The MicroRNA and MessengerRNA Profile of the RNA-Induced Silencing Complex in Human Primary Astrocyte and Astrocytoma Cells

Moser, J. J., & Fritzler, M. J. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013445 · Cited by 28 · see citing works

The Utility of Gene Expression in Blood Cells for Diagnosing Neuropsychiatric Disorders

Woelk, C. H., Singhania, A., Pérez‐Santiago, J., Glatt, S. J., & Tsuang, M. T. (2011) · International review of neurobiology · doi:10.1016/b978-0-12-387718-5.00003-1 · Cited by 26 · see citing works

5-Lipoxygenase as a Putative Link Between Cardiovascular and Psychiatric Disorders

Manev, R. M., & Manev, H. (2004) · Critical Reviews in Neurobiology · doi:10.1615/critrevneurobiol.v16.i12.190 · Cited by 25 · see citing works

Feasibility and relevance of examining lymphoblastoid cell lines to study role of microRNAs in autism

Talebizadeh, Z., Butler, M. G., & Theodoro, M. F. (2008) · Autism Research · doi:10.1002/aur.46 · Cited by 19 · see citing works

RNA secondary structures located in the interchromosomal region of human ACAT1 chimeric mRNA are required to produce the 56-kDa isoform

Chen, J., Zhao, X., Yang, L. C., Hu, G., Lü, M., Xiong, Y., Yang, X., Chang, C. C. Y., Song, B., Chang, T., et al. (2008) · Cell Research · doi:10.1038/cr.2008.66 · Cited by 16 · see citing works

MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling

Mellios, N., Feldman, D., Sheridan, S. D., Ip, J. P. K., Kwok, S., Amoah, S. K., Rosen, B. P., Rodriguez, B. A., Crawford, B., Swaminathan, R., et al. (2017) · Molecular Psychiatry · doi:10.1038/mp.2017.86 · Cited by 288 · see citing works

Rett syndrome: insights into genetic, molecular and circuit mechanisms

Ip, J. P. K., Mellios, N., & Sur, M. (2018) · Nature reviews. Neuroscience · doi:10.1038/s41583-018-0006-3 · Cited by 247 · see citing works

The human BDNF gene: peripheral gene expression and protein levels as biomarkers for psychiatric disorders

Cattaneo, A., Cattane, N., Begni, V, Pariante, C. M., & Riva, M. A. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.214 · Cited by 244 · see citing works

An epigenetic framework for neurodevelopmental disorders: From pathogenesis to potential therapy

Millan, M. J. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.11.015 · Cited by 229 · see citing works

Genome-wide, integrative analysis implicates microRNA dysregulation in autism spectrum disorder

Wu, Y. E., Parikshak, N. N., Belgard, T. G., & Geschwind, D. H. (2016) · Nature Neuroscience · doi:10.1038/nn.4373 · Cited by 195 · see citing works

Biomarkers in autism spectrum disorder: the old and the new

Ruggeri, B., Sarkans, U., Schumann, G., & Persico, A. M. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3290-7 · Cited by 191 · see citing works

Delineating the 15q13.3 microdeletion phenotype: a case series and comprehensive review of the literature

Lowther, C., Costain, G., Stavropoulos, D. J., Melvin, R., Silversides, C. K., Andrade, D. M., So, J., Faghfoury, H., Lionel, A. C., Marshall, C. R., et al. (2014) · Genetics in Medicine · doi:10.1038/gim.2014.83 · Cited by 174 · see citing works

Circulating cell-free microRNA as biomarkers for screening, diagnosis and monitoring of neurodegenerative diseases and other neurologic pathologies

Sheinerman, K. S., & Umansky, S. R. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00150 · Cited by 171 · see citing works

Salivary biomarkers for the diagnosis and monitoring of neurological diseases

Farah, R., Haraty, H., Salame, Z., Fares, Y., Ojcius, D. M., & Sadier, N. S. (2018) · Biomedical Journal · doi:10.1016/j.bj.2018.03.004 · Cited by 170 · see citing works

Emerging role of microRNAs in major depressive disorder: diagnosis and therapeutic implications

Dwivedi, Y. (2014) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2014.16.1/ydwivedi · Cited by 169 · see citing works

Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder

Bavamian, S., Mellios, N., Lalonde, J., Fass, D. M., Wang, J., Sheridan, S. D., Madison, J. M., Zhou, F., Rueckert, E. H., Barker, D., et al. (2015) · Molecular Psychiatry · doi:10.1038/mp.2014.176 · Cited by 162 · see citing works

A psychiatric disease-related circular RNA controls synaptic gene expression and cognition

Zimmerman, A. J., Hafez, A. K., Amoah, S. K., Rodriguez, B. A., Dell’Orco, M., Lozano, E., Hartley, B. J., Alural, B., Lalonde, J., Chander, P. N., et al. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-0653-4 · Cited by 152 · see citing works

Integrating the roles of long and small non-coding RNA in brain function and disease

Barry, G. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.196 · Cited by 150 · see citing works

Diagnostic and therapeutic potentials of exosomes in CNS diseases

Kawiková, I., & Askenase, P. W. (2014) · Brain Research · doi:10.1016/j.brainres.2014.09.070 · Cited by 144 · see citing works

The Impact of Neuroimmune Alterations in Autism Spectrum Disorder

Gottfried, C., Bambini-Junior, V., Francis, F., Riesgo, R., & Savino, W. (2015) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2015.00121 · Cited by 143 · see citing works

Friends with social benefits: host-microbe interactions as a driver of brain evolution and development?

Stilling, R. M., Bordenstein, S. R., Dinan, T. G., & Cryan, J. F. (2014) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2014.00147 · Cited by 135 · see citing works

MicroRNA-132 Is Enriched in Developing Axons, Locally Regulates Rasa1 mRNA, and Promotes Axon Extension

Hancock, M., Preitner, N., Quan, J., & Flanagan, J. G. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.3371-13.2014 · Cited by 135 · see citing works

Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex

Guella, I., Sequeira, A., Rollins, B. L., Morgan, L., Torri, F., van Erp, T. G. M., Myers, R., Barchas, J. D., Schatzberg, A. F., Watson, S. J., et al. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.05.021 · Cited by 132 · see citing works

Epigenetics of Autism Spectrum Disorder

Siu, M. T., & Weksberg, R. (2017) · Advances in Experimental Medicine and Biology · doi:10.1007/978-3-319-53889-1_4 · Cited by 121 · see citing works

Decreased DGCR8 Expression and miRNA Dysregulation in Individuals with 22q11.2 Deletion Syndrome

Sellier, C., Hwang, V. J., Dandekar, R., Durbin-Johnson, B. P., Charlet‐Berguerand, N., Ander, B. P., Sharp, F. R., Angkustsiri, K., Simon, T. J., & Tassone, F. (2014) · PLoS ONE · doi:10.1371/journal.pone.0103884 · Cited by 86 · see citing works

microRNA-128a dysregulation in transgenic Huntington’s disease monkeys

Kocerha, J., Xu, Y. C., Prucha, M. S., Zhao, D., & Chan, A. W. S. (2014) · Molecular Brain · doi:10.1186/1756-6606-7-46 · Cited by 79 · see citing works

In vivoknockdown of hippocampal miR-132 expression impairs memory acquisition of trace fear conditioning

Wang, R.-Y., Phang, R.-Z., Hsu, P.-H., Wang, W., Huang, H.-T., & Liu, I. Y. (2013) · Hippocampus · doi:10.1002/hipo.22123 · Cited by 79 · see citing works

MicroRNAs in depression and suicide: Recent insights and future perspectives

Dwivedi, Y. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.07.075 · Cited by 77 · see citing works

The putative role of environmental aluminium in the development of chronic neuropathology in adults and children. How strong is the evidence and what could be the mechanisms involved?

Morris, G., Puri, B. K., & Frye, R. E. (2017) · Metabolic Brain Disease · doi:10.1007/s11011-017-0077-2 · Cited by 76 · see citing works

Dysregulation of mi RNA and its potential therapeutic application in schizophrenia

Cao, T., & Zhen, X. (2018) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12840 · Cited by 71 · see citing works

β2-Adrenergic receptor agonist ameliorates phenotypes and corrects microRNA-mediated IGF1 deficits in a mouse model of Rett syndrome

Mellios, N., Woodson, J., Garcia, R. I., Crawford, B., Sharma, J., Sheridan, S. D., Haggarty, S. J., & Sur, M. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1309426111 · Cited by 69 · see citing works

Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders

Ander, B. P., Barger, N., Stamova, B. S., Sharp, F. R., & Schumann, C. M. (2015) · Molecular Autism · doi:10.1186/s13229-015-0029-9 · Cited by 68 · see citing works

Post-transcriptional regulation of SHANK3 expression by microRNAs related to multiple neuropsychiatric disorders

Choi, S., Pang, K., Kim, J. Y., Ryu, J. R., Kang, H., Liu, Z., Kim, W.-K., Sun, W., Kim, H., & Han, K. (2015) · Molecular Brain · doi:10.1186/s13041-015-0165-3 · Cited by 69 · see citing works

Microbiome to Brain: Unravelling the Multidirectional Axes of Communication

Aidy, S. E., Stilling, R. M., Dinan, T. G., & Cryan, J. F. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-20215-0_15 · Cited by 64 · see citing works

MicroRNA and diseases: Therapeutic potential as new generation of drugs

Wahid, F., Khan, T., & Kim, Y. Y. (2014) · Biochimie · doi:10.1016/j.biochi.2014.05.004 · Cited by 54 · see citing works

HIV-1 Tat-shortened neurite outgrowth through regulation of microRNA-132 and its target gene expression

Rahimian, P., & He, J. J. (2016) · Journal of Neuroinflammation · doi:10.1186/s12974-016-0716-2 · Cited by 52 · see citing works

Maturation of the Human Dorsolateral Prefrontal Cortex Coincides With a Dynamic Shift in MicroRNA Expression

Beveridge, N. J., Santarelli, D. M., Wang, X., Tooney, P. A., Webster, M. J., Weickert, C. S., & Cairns, M. J. (2013) · Schizophrenia Bulletin · doi:10.1093/schbul/sbs198 · Cited by 52 · see citing works

Altered circulatory levels of miR-128, BDNF, cortisol and shortened telomeres in patients with type 2 diabetes and depression

Paramasivam, P., Poongothai, S., Shanthirani, C. S., Anjana, R. M., Mohan, V., & Balasubramanyam, M. (2020) · Acta Diabetologica · doi:10.1007/s00592-020-01486-9 · Cited by 52 · see citing works

Role of Dicer and the miRNA system in neuronal plasticity and brain function

Fiorenza, A., & Barco, Á. (2016) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2016.05.001 · Cited by 50 · see citing works

From Genetics to Epigenetics: New Perspectives in Tourette Syndrome Research

Pagliaroli, L., Vető, B., Arányi, T., & Barta, C. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00277 · Cited by 48 · see citing works

The emerging roles of MicroRNAs in autism spectrum disorders

Fregeac, J., Colleaux, L., & Nguyen, L. S. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.10.018 · Cited by 51 · see citing works

Epigenetic Mechanisms in Autism Spectrum Disorder

Zhubi, A., Cook, E. H., Guidotti, A., & Grayson, D. R. (2014) · International review of neurobiology · doi:10.1016/b978-0-12-801311-3.00006-8 · Cited by 51 · see citing works

Towards understanding sex differences in autism spectrum disorders

Leow, K. Q., Tonta, M. A., Lü, J., Coleman, H. A., & Parkington, H. C. (2024) · Brain Research · doi:10.1016/j.brainres.2024.148877 · Cited by 50 · see citing works

Integrated Post-GWAS Analysis Sheds New Light on the Disease Mechanisms of Schizophrenia

Lin, J.-R., Cai, Y., Zhang, Q., Zhang, W., Nogales‐Cadenas, R., & Zhang, Z. D. (2016) · Genetics · doi:10.1534/genetics.116.187195 · Cited by 47 · see citing works

Exploring Transcription Factors-microRNAs Co-regulation Networks in Schizophrenia

Xu, Y. J., Yue, W., Shugart, Y. Y., Li, S., Cai, L., Li, Q., Cheng, Z., Wang, G., Zhou, Z., Jin, C., et al. (2015) · Schizophrenia Bulletin · doi:10.1093/schbul/sbv170 · Cited by 46 · see citing works

Biomarker investigations related to pathophysiological pathways in schizophrenia and psychosis

Chana, G., Bousman, C., Money, T., Gibbons, A. S., Gillett, P., Dean, B., & Everall, I. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00095 · Cited by 44 · see citing works

Maternal Diabetes and Fetal Programming Toward Neurological Diseases: Beyond Neural Tube Defects

Márquez-Valadez, B., Valle-Bautista, R., García-López, G., Díaz, N., & Molina-Hernández, A. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00664 · Cited by 40 · see citing works

Human urine-derived stem cell-derived exosomal miR-21-5p promotes neurogenesis to attenuate Rett syndrome via the EPha4/TEK axis

Pan, W., Xu, X., Zhang, M., & Song, X. (2021) · Laboratory Investigation · doi:10.1038/s41374-021-00574-w · Cited by 42 · see citing works

miRNA-mediated risk for schizophrenia in 22q11.2 deletion syndrome

Brzustowicz, L. M., & Bassett, A. S. (2012) · Frontiers in Genetics · doi:10.3389/fgene.2012.00291 · Cited by 41 · see citing works

Circulating miRNAs, Small but Promising Biomarkers for Autism Spectrum Disorder

Salloum‐Asfar, S., Satheesh, N. J., & Abdulla, S. A. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00253 · Cited by 41 · see citing works

Meta gene set enrichment analyses link miR-137-regulated pathways with schizophrenia risk

Wright, C., Calhoun, V. D., Ehrlich, S., Wang, L., Turner, J. A., & Perrone‐Bizzozero, N. I. (2015) · Frontiers in Genetics · doi:10.3389/fgene.2015.00147 · Cited by 40 · see citing works

Mining the 3′UTR of Autism-Implicated Genes for SNPs Perturbing MicroRNA Regulation

Vaishnavi, V., Manikandan, M., & Munirajan, A. K. (2014) · Genomics Proteomics & Bioinformatics · doi:10.1016/j.gpb.2014.01.003 · Cited by 40 · see citing works

Meta-analysis of genome-wide SNP- and pathway-based associations for facets of neuroticism

Kim, S. E., Kim, H., Yun, Y.-J., Heo, S. G., Cho, J., Kwon, M., Chang, Y., Ryu, S., Shin, C., Shin, C., et al. (2017) · Journal of Human Genetics · doi:10.1038/jhg.2017.61 · Cited by 38 · see citing works

A Review of Molecular Interplay between Neurotrophins and miRNAs in Neuropsychological Disorders

Abdolahi, S., Zare-Chahoki, A., Noorbakhsh, F., & Gorji, A. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-02966-5 · Cited by 36 · see citing works

Circulating miRNAs profiles in tourette syndrome: molecular data and clinical implications

Rizzo, R., Ragusa, M., Barbagallo, C., Sammito, M., Gulisano, M., Calì, P. V., Pappalardo, C., Barchitta, M., Granata, M., Condorelli, A. G., et al. (2015) · Molecular Brain · doi:10.1186/s13041-015-0133-y · Cited by 35 · see citing works

Converging Evidence Implicates the Abnormal MicroRNA System in Schizophrenia

Zhang, F., Xu, Y. J., Shugart, Y. Y., Yue, W., Qi, G., Yuan, G., Cheng, Z., Yao, J., Wang, J., Wang, G., et al. (2014) · Schizophrenia Bulletin · doi:10.1093/schbul/sbu148 · Cited by 34 · see citing works

Specific Regional and Age-Related Small Noncoding RNA Expression Patterns Within Superior Temporal Gyrus of Typical Human Brains Are Less Distinct in Autism Brains

Stamova, B. S., Ander, B. P., Barger, N., Sharp, F. R., & Schumann, C. M. (2015) · Journal of Child Neurology · doi:10.1177/0883073815602067 · Cited by 35 · see citing works

Developmental exposure to valproic acid alters the expression of microRNAs involved in neurodevelopment in zebrafish

Aluru, N., Deak, K. L., Jenny, M. J., & Hahn, M. E. (2013) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2013.10.001 · Cited by 31 · see citing works

Prenatal exposure to valproic acid increases miR-132 levels in the mouse embryonic brain

Hara, Y., Ago, Y., Takano, E., Hasebe, S., Nakazawa, T., Hashimoto, H., Matsuda, T., & Takuma, K. (2017) · Molecular Autism · doi:10.1186/s13229-017-0149-5 · Cited by 31 · see citing works

Maternal Diabetes Alters Expression of MicroRNAs that Regulate Genes Critical for Neural Tube Development

Ramya, S., Shyamasundar, S., Bay, B., & Dheen, S. T. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00237 · Cited by 33 · see citing works

Transcriptome analysis reveals disparate expression of inflammation-related miRNAs and their gene targets in iPSC-astrocytes from people with schizophrenia

Akkouh, I. A., Hughes, T., Steen, V. M., Glover, J. C., Andreassen, O. A., Djurovic, S., & Szabó, A. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.01.037 · Cited by 31 · see citing works

miRNA-Dependent Control of Homeostatic Plasticity in Neurons

Dubes, S., Favereaux, A., Thoumine, O. R., & Letellier, M. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00536 · Cited by 27 · see citing works

Functional genomics of human brain development and implications for autism spectrum disorders

Ziats, M. N., Grosvenor, L. P., & Rennert, O. M. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.153 · Cited by 26 · see citing works

Neuroepigenetics of Schizophrenia

Punzi, G., Bharadwaj, R. A., & Ursini, G. (2018) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2018.04.010 · Cited by 26 · see citing works

The role of microRNAs in the molecular link between circadian rhythm and autism spectrum disorder

Kim, J. Y., Kim, W., & Lee, K. (2023) · Animal Cells and Systems · doi:10.1080/19768354.2023.2180535 · Cited by 24 · see citing works

Widespread transcriptional disruption of the microRNA biogenesis machinery in brain and peripheral tissues of individuals with schizophrenia

Rey, R., Suaud‐Chagny, M., Dorey, J., Teyssier, J., & d’Amato, T. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-01052-5 · Cited by 23 · see citing works

Genomic Editing of Non-Coding RNA Genes with CRISPR/Cas9 Ushers in a Potential Novel Approach to Study and Treat Schizophrenia

Zhuo, C., Hou, W., Hu, L., Lin, C., Chen, C., & Lin, X. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00028 · Cited by 23 · see citing works

Epistatic and independent effects on schizophrenia-related phenotypes following co-disruption of the risk factors neuregulin-1 × DISC1

O’Tuathaigh, C. M. P., Fumagalli, F., Desbonnet, L., Perez-Branguli, F., Moloney, G., Loftus, S., O’Leary, C., Petit, E., Cox, R., Tighe, O., et al. (2017) · Schizophrenia Bulletin · doi:10.1093/schbul/sbw120 · Cited by 22 · see citing works

Down-Regulation of miRNA-708 Promotes Aberrant Calcium Signaling by Targeting Neuronatin in a Mouse Model of Angelman Syndrome

Vatsa, N., Kumar, V., Singh, B. K., Kumar, R., Sharma, A., & Jana, N. R. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00035 · Cited by 20 · see citing works

Turing Revisited: Decoding the microRNA Messages in Brain Extracellular Vesicles for Early Detection of Neurodevelopmental Disorders

Gillet, V., Hunting, D. J., & Takser, L. (2016) · Current Environmental Health Reports · doi:10.1007/s40572-016-0093-0 · Cited by 20 · see citing works

The Role of microRNA Expression in Cortical Development During Conversion to Psychosis

Zheutlin, A. B., Jeffries, C. D., Perkins, D. O., Chung, Y., Chekroud, A. M., Addington, J., Bearden, C. E., Cadenhead, K. S., Cornblatt, B. A., Mathalon, D. H., et al. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.34 · Cited by 20 · see citing works

Deregulatory miRNA-BDNF Network Inferred from Dynamic Expression Changes in Schizophrenia

Fu, X., Liu, Y., Baranova, A. V., & Zhang, F. (2022) · Brain Sciences · doi:10.3390/brainsci12020167 · Cited by 19 · see citing works

Cohesive Regulation of Neural Progenitor Development by microRNA miR-26, Its Host Gene Ctdsp and Target Gene Emx2 in the Mouse Embryonic Cerebral Cortex

Zhang, H., Zhang, L., & Sun, T. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00044 · Cited by 20 · see citing works

Profiling MicroRNAs with Associated Spatial Dynamics in Acute Tissue Slices

Xie, K., Wang, Z., Lin, Q., Zhao, X., Wang, Y., Jin, Q., Xu, P., Huang, L., Zhang, W., Yang, Y., et al. (2021) · ACS Nano · doi:10.1021/acsnano.0c09676 · Cited by 19 · see citing works

Sulforaphane improves mitochondrial metabolism in fibroblasts from patients with fragile X-associated tremor and ataxia syndrome

Napoli, E., Flores, A., Mansuri, Y., Hagerman, R. J., & Giulivi, C. (2021) · Neurobiology of Disease · doi:10.1016/j.nbd.2021.105427 · Cited by 19 · see citing works

EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia

Johnstone, A. L., O’Reilly, J. J., Patel, A. J., Guo, Z., Andrade, N. S., Magistri, M., Nathanson, L., Esanov, R., Miller, B. H., Turecki, G., et al. (2018) · Neurobiology of Disease · doi:10.1016/j.nbd.2018.08.005 · Cited by 18 · see citing works

Resveratrol Treatment of Autism Spectrum Disorder—A Pilot Study

Marchezan, J., Deckmann, I., da Fonseca, G. C., Margis, R., Riesgo, R. D. S., & Gottfried, C. (2022) · Clinical Neuropharmacology · doi:10.1097/wnf.0000000000000516 · Cited by 16 · see citing works

microPIR2: a comprehensive database for human-mouse comparative study of microRNA-promoter interactions

Piriyapongsa, J., Bootchai, C., Ngamphiw, C., & Tongsima, S. (2014) · Database · doi:10.1093/database/bau115 · Cited by 15 · see citing works

MiR-128-3p – a gray eminence of the human central nervous system

Kiel, K., Król, S. K., Bronisz, A., & Godlewski, J. (2024) · Molecular Therapy Nucleic Acids · doi:10.1016/j.omtn.2024.102141 · Cited by 15 · see citing works

MicroRNAs and pro-inflammatory cytokines as candidate biomarkers for recent-onset psychosis

Shafiee‐Kandjani, A. R., Nezhadettehad, N., Farhang, S., Bruggeman, R., Shanebandi, D., Hassanzadeh, M., & Azizi, H. (2023) · BMC Psychiatry · doi:10.1186/s12888-023-05136-6 · Cited by 14 · see citing works

First Trimester Maternal Plasma Aberrant miRNA Expression Associated with Spontaneous Preterm Birth

Mavreli, D., Theodora, M., Avgeris, M., Papantoniou, N., Antsaklis, P. G., Daskalakis, G. J., & Kοlialexi, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232314972 · Cited by 14 · see citing works

The Ins and Outs of miRNA-Mediated Gene Silencing during Neuronal Synaptic Plasticity

Rajgor, D., & Hanley, J. G. (2016) · Non-Coding RNA · doi:10.3390/ncrna2010001 · Cited by 14 · see citing works

Neonatal anesthesia exposure impacts brain microRNAs and their associated neurodevelopmental processes

Lin, D., Liu, J., Hu, Z., Cottrell, J. E., & Kass, I. S. (2018) · Scientific Reports · doi:10.1038/s41598-018-28874-0 · Cited by 14 · see citing works

New Horizons for Molecular Genetics Diagnostic and Research in Autism Spectrum Disorder

Al-Dewik, N. I. E., & Alsharshani, M. (2020) · Advances in neurobiology · doi:10.1007/978-3-030-30402-7_2 · Cited by 13 · see citing works

Deficits in Prenatal Serine Biosynthesis Underlie the Mitochondrial Dysfunction Associated with the Autism-Linked FMR1 Gene

Nolin, S., Napoli, E., Flores, A., Hagerman, R., & Giulivi, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115886 · Cited by 11 · see citing works

The Computational Analysis Conducted on miRNA Target Sites in Association with SNPs at 3’UTR of ADHD-implicated Genes

Abdi, A., Zafarpiran, M., & Shirvani-Farsani, Z. (2019) · Central Nervous System Agents in Medicinal Chemistry · doi:10.2174/1871524919666191014104843 · Cited by 12 · see citing works

Adult expression of a 3q13.31 microdeletion

Lowther, C., Costain, G., Melvin, R., Stavropoulos, D. J., Lionel, A. C., Marshall, C. R., Scherer, S. W., & Bassett, A. S. (2014) · Molecular Cytogenetics · doi:10.1186/1755-8166-7-23 · Cited by 12 · see citing works

Peering into the mind: unraveling schizophrenia’s secrets using models

Nani, J. V. S., Muotri, A. R., & Hayashi, M. A. F. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02728-w · Cited by 11 · see citing works

MiR-132 regulated olfactory bulb proteins linked to olfactory learning in greater short-nosed fruit bat Cynopterus sphinx

Mukilan, M., Rajathei, D. M., Jeyaraj, S. E., Kayalvizhi, N., & Rajan, K. E. (2018) · Gene · doi:10.1016/j.gene.2018.05.107 · Cited by 9 · see citing works

Cell ageing: a flourishing field for neurodegenerative diseases

Brites, D. M. T. O. (2015) · AIMS molecular science · doi:10.3934/molsci.2015.3.225 · Cited by 9 · see citing works

Genome-wide association study of white matter hyperintensity volume in elderly persons without dementia

Guo, Y., Shen, X., Hou, X., Ou, Y., Huang, Y., Dong, Q., Tan, L., & Yu, J. (2020) · NeuroImage Clinical · doi:10.1016/j.nicl.2020.102209 · Cited by 8 · see citing works

Epigenetics and Environmental Exposures in Early Neurodevelopment: Implications for Pediatric Neurological Disorders

Jubair, H. (2025) · Sage Open Pediatrics · doi:10.1177/30502225251380331 · Cited by 7 · see citing works

Coalitional Game Theory Facilitates Identification of Non-Coding Variants Associated With Autism

Sun, M., Gupta, A., Varma, M., Paskov, K. M., Jung, J.-Y., Stockham, N., & Wall, D. P. (2019) · Biomedical Informatics Insights · doi:10.1177/1178222619832859 · Cited by 7 · see citing works

MicroRNAs as biomarkers and molecular mediators of cognitive dysfunction in schizophrenia

Adly, N. M., Khalifa, D., Abdel-Ghany, S. E., & Sabit, H. (2025) · Journal of Neural Transmission · doi:10.1007/s00702-025-02993-1 · Cited by 6 · see citing works

Radiation neurobiology of long-term spaceflights

Олегович, С. А., Ушаков, И. Б., Sapetsky, N. V., Shtemberg, A. S., Kositsin, N. S., & Timofeev, N. N. (2017) · Biology Bulletin Reviews · doi:10.1134/s2079086417060068 · Cited by 6 · see citing works

Gene–environment interactions in human health: case studies and strategies for developing new paradigms and research methodologies

Jackson, F. L. C. (2014) · Frontiers in Genetics · doi:10.3389/fgene.2014.00271 · Cited by 6 · see citing works

MicroRNAs

Guibinga, G.-H. (2015) · Advances in genetics · doi:10.1016/bs.adgen.2015.06.001 · Cited by 5 · see citing works

Characterization of Micro RNA Signature in Peripheral Blood of Schizophrenia Patients using µParafloTM miRNA Microarray Assay

Vachev, T. I., Popov, N. T., Marchev, D., Ivanov, H. Y., & Stoyanova, V. K. (2016) · International Journal of Current Microbiology and Applied Sciences · doi:10.20546/ijcmas.2016.507.055 · Cited by 5 · see citing works

The clinical use of epigenetics in psychiatry: a narrative review of epigenetic mechanisms, key candidate genes, and precision psychiatry

Montel Hayes, R., Mason, C. E., & Miller, J. J. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1671122 · Cited by 5 · see citing works

Long non-coding RNAs in schizophrenia

Mousavinejad, S. N., Hosseini, S. A., Mohammadpour, M., Ferdosi, F., Dadgostar, E., Abdolghaderi, S., & Khatami, S. H. (2025) · Clinica Chimica Acta · doi:10.1016/j.cca.2025.120340 · Cited by 4 · see citing works

MicroRNA-Mediated Repression Combats Depression

Heyer, M. P., & Kenny, P. J. (2014) · Neuron · doi:10.1016/j.neuron.2014.07.008 · Cited by 3 · see citing works

New Challenges and Frontiers in the Research for Neuropsychiatric Disorders

Tropea, D. (2012) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2012.00069 · Cited by 3 · see citing works

miRNA as a Marker for In Vitro Neurotoxicity Testing and Related Neurological Disorders

Smirnova, L., & Maertens, A. (2019) · Neuromethods · doi:10.1007/978-1-4939-9228-7_14 · Cited by 3 · see citing works

Noncoding RNA-targeted treatment for schizophrenia: CRISPR/CAS9

Özulu, Ç., & Erbaş, O. (2021) · Demiroglu Science University Florence Nightingale Journal of Medicine · doi:10.5606/fng.btd.2021.25067 · Cited by 3 · see citing works

Epigenetic Approaches to Define the Molecular and Genetic Risk Architectures of Schizophrenia

Kundaković, M., Peter, C. J., Roussos, P., & Akbarian, S. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801829-3.00013-6 · Cited by 2 · see citing works

The Emerging Role of MicroRNA in Schizophrenia

Caputo, V., Ciolfi, A., Macrı̀, S., & Pizzuti, A. (2015) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527314666150116124253 · Cited by 32 · see citing works

Dysregulation of mi RNA and its potential therapeutic application in schizophrenia

Cao, T., & Zhen, X. (2018) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12840 · Cited by 71 · see citing works

The Dysregulation of microRNAs and the Role of Stress in the Pathogenesis of Mental Disorders

Ivanova, E., Bozhilova, R., Kaneva, R. P., & Milanova, V. K. (2018) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026619666181130135253 · Cited by 11 · see citing works

MicroRNAs: Small molecules with big roles in neurodevelopment and diseases

Sun, E., & Shi, Y. (2014) · Experimental Neurology · doi:10.1016/j.expneurol.2014.08.005 · Cited by 178 · see citing works

microRNAs Sculpt Neuronal Communication in a Tight Balance That Is Lost in Neurological Disease

Thomas, K. T., Groß, C., & Bassell, G. J. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00455 · Cited by 61 · see citing works