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Treatment with the copper compound CuATSM has no significant effect on motor neuronal pathology in patients with ALS

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Peripheral nerve atrophy together with higher cerebrospinal fluid progranulin indicate axonal damage in amyotrophic lateral sclerosis

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Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72 ‐ALS

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Pathogenic or protective? Neuropeptide Y in amyotrophic lateral sclerosis

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Microglia Morphological Changes in the Motor Cortex of hSOD1G93A Transgenic ALS Mice

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L-type Calcium Channel Cav1.2 Is Required for Maintenance of Auditory Brainstem Nuclei

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Case Studies in Neuroscience: Neuropathology and diaphragm dysfunction in ventilatory failure from late-onset Pompe disease

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Urinary neopterin, a new marker of the neuroinflammatory status in amyotrophic lateral sclerosis

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Phase 1b dose-escalation, safety, and pharmacokinetic study of IC14, a monoclonal antibody against CD14, for the treatment of amyotrophic lateral sclerosis

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Immunological drivers of amyotrophic lateral sclerosis

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An interplay between immune response and neurodegenerative disease progression: An assessment using Drosophila as a model

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Extracellular vesicles in TDP-43 proteinopathies: pathogenesis and biomarker potential

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Activation of microglial neuregulin1 signaling in the corticospinal tracts of ALS patients with upper motor neuron signs

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Pathophysiological Underpinnings of Extra-Motor Neurodegeneration in Amyotrophic Lateral Sclerosis: New Insights From Biomarker Studies

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Divergent functional outcomes of NLRP3 blockade downstream of multi-inflammasome activation: therapeutic implications for ALS

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Arginase-1 expressing microglia in close proximity to motor neurons were increased early in disease progression in canine degenerative myelopathy, a model of amyotrophic lateral sclerosis

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Tracing the History of the Human Translocator Protein to Recent Neurodegenerative and Psychiatric Imaging

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Normal aging, motor neurone disease, and Alzheimer’s disease are characterized by cortical changes in inflammatory cytokines

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Loss of calretinin- and parvalbumin-immunoreactive axons in anterolateral columns beyond the corticospinal tracts of amyotrophic lateral sclerosis spinal cords

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Age-related loss of VGLUT1 excitatory, but not VGAT inhibitory, immunoreactive terminals on motor neurons in spinal cords of old sarcopenic male mice

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Data‐independent acquisition proteomics of cerebrospinal fluid implicates endoplasmic reticulum and inflammatory mechanisms in amyotrophic lateral sclerosis

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The Current Potential Pathogenesis of Amyotrophic Lateral Sclerosis

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Loss of Endothelial TDP-43 Leads to Blood Brain Barrier Defects in Mouse Models of Amyotrophic Lateral Sclerosis and Frontotemporal DementiaPreprint

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Elevated α5 integrin expression on myeloid cells in motor areas in amyotrophic lateral sclerosis is a therapeutic target

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CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS

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Human VCP mutant ALS/FTD microglia display immune and lysosomal phenotypes independently of GPNMB

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Human amyotrophic lateral sclerosis/motor neuron disease: The disease‐associated microglial pathway is upregulated while APOE genotype governs risk and survival

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Cu II (atsm) significantly decreases microglial reactivity in patients with sporadic amyotrophic lateral sclerosis

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Turmeronols (A and B) from Curcuma longa have anti-inflammatory effects in lipopolysaccharide-stimulated BV-2 microglial cells by reducing NF-κB signaling

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Novel therapeutic targets for amyotrophic lateral sclerosis: ribonucleoproteins and cellular autonomy

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Evaluating emerging drugs in phase II & III for the treatment of amyotrophic lateral sclerosis

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Relevance of raised cerebrospinal fluid monocyte levels in patients with frontotemporal dementia

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Genistein suppresses microglial activation and inhibits apoptosis in different brain regions of hypoxia-exposed mice model of amnesia

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Assessing neuraxial microstructural changes in a transgenic mouse model of early stage Amyotrophic Lateral Sclerosis by ultra‐high field MRI and diffusion tensor metrics

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Imaging immunological processes from blood to brain in amyotrophic lateral sclerosis

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Early Signs of Neuroinflammation in the Postnatal Wobbler Mouse Model of Amyotrophic Lateral Sclerosis

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Positron emission tomography in amyotrophic lateral sclerosis: Towards targeting of molecular pathological hallmarks

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Measuring disease progression in primary lateral sclerosis

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Network Analysis of the CSF Proteome Characterizes Convergent Pathways of Cellular Dysfunction in ALS

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Pathophysiological Correlation between Cigarette Smoking and Amyotrophic Lateral Sclerosis

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Current neuroprotective therapies and future prospects for motor neuron disease

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Ferritin is closely associated with microglia in amyotrophic lateral sclerosis

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Respiratory pathology in the TDP-43 transgenic mouse model of amyotrophic lateral sclerosis

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BV-2 Microglial Cells Overexpressing C9orf72 Hexanucleotide Repeat Expansion Produce DPR Proteins and Show Normal Functionality but No RNA Foci

Rostalski, H., Hietanen, T., Leskelä, S., Beháňová, A., Abdollahzadeh, A., Wittrahm, R., Mäkinen, P. M., Huber, N., Hoffmann, D. B., Solje, E., et al. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.550140 · Cited by 5

Cellular and molecular phenotypes of C9orf72 ALS/FTD patient derived iPSC-microglia mono-culturesPreprint

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Association of peripheral immune activation with amyotrophic lateral sclerosis and Parkinson's disease: A systematic review and meta-analysis

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Amelioration of Amyotrophic Lateral Sclerosis in SOD1G93AMice by M2Microglia from Transplanted Marrow

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Estimating acceleration time point of respiratory decline in ALS patients: A novel metric

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ALSUntangled No. 19: Sodium chlorite

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Current nano/biotechnological approaches in amyotrophic lateral sclerosis

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Head Injury and Amyotrophic Lateral Sclerosis: Population-Based Study from the National ALS Registry

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Emerging anti-inflammatory nanosystems targeted to the brain

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dock8 deficiency attenuates microglia colonization in early zebrafish larvae

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The role of glial cells in amyotrophic lateral sclerosis

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Optineurin knock-out forms TDP-43 aggregates to regulate TDP-43 protein levels despite autophagic up-regulation and aberrant TDP-43 expression

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Understanding the role of microglia in the pathogenesis of amyotrophic lateral sclerosis

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Microglia in C9orf72–associated amyotrophic lateral sclerosis: More or less active?

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Hexanucleotide repeat expansions in C9orf72 alter microglial responses and prevent a coordinated glial reaction in ALSPreprint

Masrori, P., Bijnens, B., Davie, K., Poovathingal, S. K., Storm, A., Hersmus, N., Fumagalli, L., Bosch, L. V. D., Fiers, M. W. E. J., Thal, D. R., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.26.513909 · Cited by 4

Hexanucleotide repeat expansions in C9orf72 alter microglial responses and prevent a coordinated glial reaction in ALS (P1-6.002)

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C9orf72 hexanucleotide repeat expansions impair microglial response in ALS

Masrori, P., Bijnens, B., Fumagalli, L., Davie, K., Poovathingal, S. K., Meese, T., Storm, A., Hersmus, N., Fazal, R., van den Biggelaar, D., et al. (2025) · Nature Neuroscience · doi:10.1038/s41593-025-02075-1 · Cited by 36