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Prevalence, Determinants and Patterns of Multimorbidity in Primary Care: A Systematic Review of Observational Studies
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INTRODUCTION: Multimorbidity is a major concern in primary care. Nevertheless, evidence of prevalence and patterns of multimorbidity, and their determinants, are scarce. The aim of this study is to systematically review studies of the prevalence, patterns and determinants of multimorbidity in primary care. METHODS: Systematic review of literature published between 1961 and 2013 and indexed in Ovid (CINAHL, PsychINFO, Medline and Embase) and Web of Knowledge. Studies were selected according to eligibility criteria of addressing prevalence, determinants, and patterns of multimorbidity and using a pretested proforma in primary care. The quality and risk of bias were assessed using STROBE criteria. Two researchers assessed the eligibility of studies for inclusion (Kappa= 0.86). RESULTS: We identified 39 eligible publications describing studies that included a total of 70,057,611 patients in 12 countries. The number of health conditions analysed per study ranged from 5 to 335, with multimorbidity prevalence ranging from 12.9% to 95.1%. All studies observed a significant positive association between multimorbidity and age (odds ratio [OR], 1.26 to 227.46), and lower socioeconomic status (OR, 1.20 to 1.91). Positive associations with female gender and mental disorders were also observed. The most frequent patterns of multimorbidity included osteoarthritis together with cardiovascular and/or metabolic conditions. CONCLUSIONS: Well-established determinants of multimorbidity include age, lower socioeconomic status and gender. The most prevalent conditions shape the patterns of multimorbidity. However, the limitations of the current evidence base means that further and better designed studies are needed to inform policy, research and clinical practice, with the goal of improving health-related quality of life for patients with multimorbidity. Standardization of the definition and assessment of multimorbidity is essential in order to better understand this phenomenon, and is a necessary immediate step.
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“as Violan et al 4 highlight, multimorbidity is now considered the norm rather than exception in primary care patients”
From Investigating the effectiveness of an online acceptance and commitment therapy (ACT) intervention versus a waiting list control condition on pain interference and quality of life in adults with chronic pain and multimorbidity: Protocol for a randomised controlled trial (2019) · cites this paper as [4]
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Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
Wang, G., Ma, R., Qiao, G., Wada, K., Aizawa, Y., & Satoh, T. (2015) · Integrative Medicine International · doi:10.1159/000368408 · Cited by 18,762
Vandenbroucke, J. P., von Elm, E., Altman, D. G., Gøtzsche, P. C., Mulrow, C. D., Pocock, S. J., Poole, C., Schlesselman, J. J., Egger, M., & Initiative, F. T. S. (2007) · PLoS Medicine · doi:10.1371/journal.pmed.0040297 · Cited by 8,613 · cited 1×
“Two authors (CV and QFB) used the STROBE checklist for observational studies to assess the quality of each study (Table S2) [13].”
MethodBarnett, K., Mercer, S. W., Norbury, M., Watt, G., Wyke, S., & Guthrie, B. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60240-2 · Cited by 6,972
Vandenbroucke, J. P., Elm, E. V., Altman, D. G., Gøtzsche, P. C., Mulrow, C. D., Pocock, S. J., Poole, C., Schlesselman, J. J., Egger, M., & initiative, F. T. S. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-147-8-200710160-00010-w1 · Cited by 3,543
Aging with multimorbidity: A systematic review of the literature
Marengoni, A., Angleman, S., Melis, R., Mangialasche, F., Karp, A., Garmen, A., Meinow, B., & Fratiglioni, L. (2011) · Ageing Research Reviews · doi:10.1016/j.arr.2011.03.003 · Cited by 3,092
Prevalence, Expenditures, and Complications of Multiple Chronic Conditions in the Elderly
Wolff, J. L., Starfield, B. H., & Anderson, G. F. (2002) · Archives of Internal Medicine · doi:10.1001/archinte.162.20.2269 · Cited by 2,237
Defining Comorbidity: Implications for Understanding Health and Health Services
Valderas, J. M., Starfield, B. H., Sibbald, B., Salisbury, C., & Roland, M. O. (2009) · The Annals of Family Medicine · doi:10.1370/afm.983 · Cited by 1,730
Self-citation
Flagged first, then by citations
Research works printed but not linked: 1
- P Abete, 2004, Comorbility in the elderly: Epidemiology and clinical features, G Gerontol, 52, 267
Cited by
Sorted by citations
Items 201–300 of 1,000
Disparities in multimorbidity across Europe – Findings from the SHARE Survey
Nielsen, C. R., Halling, A., & Andersen‐Ranberg, K. (2016) · European Geriatric Medicine · doi:10.1016/j.eurger.2016.11.010 · Cited by 43
Choi, E. P. H., Wan, E. Y. F., Kwok, J. Y. Y., Chin, W. Y., & Lam, C. L. K. (2019) · Health and Quality of Life Outcomes · doi:10.1186/s12955-019-1251-5 · Cited by 43
Clustering and Healthcare Costs With Multiple Chronic Conditions in a US Study
Hajat, C., Siegal, Y., & Adler-Waxman, A. (2021) · Frontiers in Public Health · doi:10.3389/fpubh.2020.607528 · Cited by 43
Kassaw, A. T., Sendekie, A. K., Minyihun, A., & Gebresillassie, B. M. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1369569 · Cited by 42
Multi-PAP Group, Prados‐Torres, A., del Cura-González, I., Prados-Torres, D., López-Rodríguez, J. A., Leiva-Fernández, F., Calderón‐Larrañaga, A., López-Verde, F., Gimeno-Feliú, L. A., Escortell‐Mayor, E., et al. (2017) · Implementation Science · doi:10.1186/s13012-017-0584-x · Cited by 42
Self-citationJacob, L., Haro, J. M., & Koyanagi, A. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.02.063 · Cited by 42
Schäfer, I., Kaduszkiewicz, H., Mellert, C., Löffler, C., Mortsiefer, A., Ernst, A., Stolzenbach, C.-O., Wiese, B., Abholz, H., Scherer, M., et al. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-017653 · Cited by 42
Factors associated with multimorbidity in the elderly: an integrative literature review
de Melo, L. A., Braga, L. D. C., Leite, F. P. P., Bittar, B. F., Oséas, J. M. D. F., & de Lima, K. C. (2019) · Revista Brasileira de Geriatria e Gerontologia · doi:10.1590/1981-22562019022.180154 · Cited by 42
A genetic model for multimorbidity in young adults
Malecki, S. L., van Mil, S., Graffi, J., Breetvelt, E., Corral, M. R., Boot, E., Chow, E. W. C., Sanches, M., Verma, A. A., & Bassett, A. S. (2019) · Genetics in Medicine · doi:10.1038/s41436-019-0603-1 · Cited by 42
Kumar, R. G., Ketchum, J. M., Corrigan, J. D., Hammond, F. M., Sevigny, M., & Dams-O’Connor, K. (2020) · Journal of Head Trauma Rehabilitation · doi:10.1097/htr.0000000000000572 · Cited by 42
Patterns and Determinants of Multimorbidity in Older Adults: Study in Health-Ecological Perspective
Chen, Y., Shi, L., Zheng, X., Yang, J., Xue, Y., Xiao, S., Xue, B., Zhang, J., Li, X., Lin, H., et al. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192416756 · Cited by 41
Clinical encounters in the post-guidelines era
Elwyn, G. J., Wieringa, S., & Greenhalgh, T. (2016) · BMJ · doi:10.1136/bmj.i3200 · Cited by 44
Medication Adherence Among Patients with Multimorbidity in the United Arab Emirates
Allaham, K., Feyasa, M. B., Govender, R. D., Musa, A. M., AlKaabi, A. J., Elbarazi, I., AlSheryani, S. D., Falasi, R. J. A., & Khan, M. A. (2022) · Patient Preference and Adherence · doi:10.2147/ppa.s355891 · Cited by 41
Gimeno-Feliú, L. A., Calderón‐Larrañaga, A., Díaz, E., Laguna-Berna, C., Poblador‐Plou, B., Coscollar, C., & Prados‐Torres, A. (2017) · Family Practice · doi:10.1093/fampra/cmx048 · Cited by 40
From chronic conditions to relevance in multimorbidity: a four-step study in family medicine
N’Goran, A. A., Blaser, J., Déruaz‐Luyet, A., Senn, N., Frey, P., Haller, D. M., Tandjung, R., Zeller, A., Burnand, B., & Herzig, L. (2016) · Family Practice · doi:10.1093/fampra/cmw030 · Cited by 40
Tobacco and alcohol use disorders: evaluating multimorbidity
MacLean, R. R., Sofuoglu, M., & Rosenheck, R. (2018) · Addictive Behaviors · doi:10.1016/j.addbeh.2017.11.006 · Cited by 39
Inequalities in multimorbidity among elderly: a population-based study in a city in Southern Brazil
Costa, C. D. S., Flores, T. R., Wendt, A. T., Neves, R. G., Tomasi, E., César, J. A., Bertoldi, A. D., Ramires, V. V., & Nunes, B. P. (2018) · Cadernos de Saúde Pública · doi:10.1590/0102-311x00040718 · Cited by 39
Lifestyle factors and multimorbidity among older adults (ELSI-Brazil)
de Almeida, M. G. N., Nascimento-Souza, M. A., Lima‐Costa, M. F., & Peixoto, S. V. (2020) · European Journal of Ageing · doi:10.1007/s10433-020-00560-z · Cited by 39
Schmitz, A., & Lazarevič, P. (2020) · European Journal of Ageing · doi:10.1007/s10433-020-00559-6 · Cited by 41
Medication patterns in older adults with multimorbidity: a cluster analysis of primary care patients
Guisado‐Clavero, M., Violán, C., López‐Jiménez, T., Roso‐Llorach, A., Pons‐Vigués, M., Muñoz, M. Á., & Boreu, Q. F. (2019) · BMC Family Practice · doi:10.1186/s12875-019-0969-9 · Cited by 38
Chronic diseases in the paediatric population: Comorbidities and use of primary care services
Cortés, J. B., Fernández, C. S., de Oliveira, M. B., Lagos, C. M., Martínez, M. T. B., Lozano-Hernández, C., & del Cura-González, I. (2020) · Anales de Pediatría (English Edition) · doi:10.1016/j.anpede.2019.12.006 · Cited by 38
Kyprianidou, M., Panagiotakos, D. B., Faka, A., Kambanaros, M., Makris, K. C., & Christophi, C. A. (2020) · Public Health Nutrition · doi:10.1017/s1368980020004267 · Cited by 38
Coste, J., Valderas, J. M., & Carcaillon‐Bentata, L. (2021) · PLoS Medicine · doi:10.1371/journal.pmed.1003584 · Cited by 38
Self-citationMuhammad, T., Boro, B., Kumar, M., & Srivastava, S. (2022) · BMC Geriatrics · doi:10.1186/s12877-022-02869-z · Cited by 38
Otieno, P., Agyemang, C. O., Wao, H., Wambiya, E. O. A., Ng’oda, M. A., Mwanga, D. M., Oguta, J. O., Kibe, P. M., & Asiki, G. (2023) · BMJ Open · doi:10.1136/bmjopen-2023-073652 · Cited by 37
Dinh, T. T. H., Nguyen, N. T., & Bonner, A. (2020) · Nursing and Health Sciences · doi:10.1111/nhs.12785 · Cited by 39
Association between Sense of Loneliness and Quality of Life in Older Adults with Multimorbidity
Vespa, A., Spatuzzi, R., Fabbietti, P., Rosa, M. D., Bonfigli, A. R., Corsonello, A., Gattafoni, P., & Giulietti, M. V. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20032615 · Cited by 39
Guthrie, B., Thompson, A., Dumbreck, S., Flynn, A., Alderson, P., Nairn, M., Treweek, S. P., & Payne, K. (2017) · Health Services and Delivery Research · doi:10.3310/hsdr05160 · Cited by 36
Contant, É., Loignon, C., Bouhali, T., Almirall, J., & Fortin, M. (2019) · BMC Family Practice · doi:10.1186/s12875-019-0943-6 · Cited by 39
Association of patterns of multimorbidity with length of stay
Aubert, C. E., Schnipper, J. L., Fankhauser, N., Marques-Vidal, P. M., Stirnemann, J., Auerbach, A. D., Zimlichman, E., Kripalani, S. B., Vasilevskis, E. E., Robinson, E. J., et al. (2020) · Medicine · doi:10.1097/md.0000000000021650 · Cited by 36
Rohini, C., & Jeemon, P. (2020) · Wellcome Open Research · doi:10.12688/wellcomeopenres.16326.1 · Cited by 36
Lee, E. S., Lee, S., Xie, Y., Ryan, B. L., Fortin, M., & Stewart, M. (2021) · BMC Public Health · doi:10.1186/s12889-021-11464-7 · Cited by 36
Ricci‐Cabello, I., Violán, C., Boreu, Q. F., Mounce, L. T. A., & Valderas, J. M. (2015) · European Journal of General Practice · doi:10.3109/13814788.2015.1046046 · Cited by 38
Self-citationHeyland, D. K., Pope, J. P., Jiang, X., & Day, A. G. (2021) · Health and Quality of Life Outcomes · doi:10.1186/s12955-021-01759-z · Cited by 35
Otieno, P. O., Asiki, G., Wekesah, F. M., Wilunda, C., Sanya, R. E., Wami, W. M., & Agyemang, C. O. (2023) · BMJ Open · doi:10.1136/bmjopen-2022-064275 · Cited by 35
Long-term disease interactions amongst surgical patients: a population cohort study
Fowler, A. J., Wahedally, M. A. H., Abbott, T. E. F., Prowle, J. R., Cromwell, D. A., & Pearse, R. M. (2023) · British Journal of Anaesthesia · doi:10.1016/j.bja.2023.04.041 · Cited by 35
Multimorbidity in old age and its impact on life results
Brijoux, T., Woopen, C., & Zank, S. (2021) · Zeitschrift für Gerontologie und Geriatrie · doi:10.1007/s00391-021-01920-9 · Cited by 35
Different phases of aging in mouse old skeletal muscle
Kang, Y., Min, B., Eom, J., & Park, J. S. (2022) · Aging · doi:10.18632/aging.203812 · Cited by 37
Smith, L., Shin, J. I., Jacob, L., Schuch, F. B., Oh, H. Y., Tully, M. A., Sánchez, G. F. L., Veronese, N., Soysal, P., Yang, L., et al. (2022) · Maturitas · doi:10.1016/j.maturitas.2022.01.007 · Cited by 35
North, C. S., Brown, E. S., & Pollio, D. E. (2016) · Annals of Clinical Psychiatry · doi:10.1177/104012371602800307 · Cited by 34
Managing multimorbidity in primary care in patients with chronic respiratory conditions
Morrison, D., Agur, K., Mercer, S. W., Eiras, A., González-Montalvo, J. I., & Gruffydd‐Jones, K. (2016) · npj Primary Care Respiratory Medicine · doi:10.1038/npjpcrm.2016.43 · Cited by 34
Kugathasan, P., Wu, H., Gaughran, F., Nielsen, R. E., Pritchard, M., Dobson, R., Stewart, R. J., & Stubbs, B. (2019) · Schizophrenia Research · doi:10.1016/j.schres.2019.10.061 · Cited by 34
Chang, E. T., Zulman, D. M., Nelson, K. M., Rosland, A.-M. M., Ganz, D. A., Fihn, S. D., Piegari, R. I., & Rubenstein, L. V. (2020) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.8120 · Cited by 37
Gondek, D., Bann, D., Brown, M., Hamer, M., Sullivan, A., & Ploubidis, G. B. (2021) · BMC Public Health · doi:10.1186/s12889-021-11291-w · Cited by 34
AlKhatib, A. H., Nnyanzi, L. A., Mujuni, B., Amanya, G., & Ibingira, C. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182312449 · Cited by 34
MacRae, C., McMinn, M., Mercer, S. W., Henderson, D., McAllister, D., Ho, I., Jefferson, E., Morales, D. R., Lyons, J., Lyons, R. A., et al. (2023) · PLoS Medicine · doi:10.1371/journal.pmed.1004208 · Cited by 39
Multimorbidity in Chronic Conditions: Public Primary Care Patients in Four Greater Mekong Countries
Pengpid, S., & Peltzer, K. (2017) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph14091019 · Cited by 34
Velek, P., Luik, A. I., Brusselle, G., Stricker, B. H. C., Bindels, P., Kavousi, M., Kieboom, B. C. T., Voortman, T., Ruiter, R., Ikram, M. A., et al. (2022) · BMC Medicine · doi:10.1186/s12916-022-02487-x · Cited by 33
Perceived Value of eHealth among People Living with Multimorbidity: A Qualitative Study
Jørgensen, S. M., Schiøtz, M. L., & Christensen, U. (2017) · Journal of Comorbidity · doi:10.15256/joc.2017.7.98 · Cited by 33
Lesende, I. M., Crespo, L. I. M., Manzanares, S. C., Otter, A.-S. D., Bilbao, I. G., Rodríguez, J. P., Pérez, I. N., Azcoaga, I. S., & Fernández, M. J. D. L. R. (2018) · BMJ Open · doi:10.1136/bmjopen-2018-022377 · Cited by 33
Tetzlaff, J., Epping, J., Sperlich, S., Eberhard, S., Stahmeyer, J. T., & Geyer, S. (2018) · International Journal for Equity in Health · doi:10.1186/s12939-018-0815-z · Cited by 33
Aubert, C. E., Fankhauser, N., Marques-Vidal, P. M., Stirnemann, J., Aujesky, D., Limacher, A., & Donzé, J. D. (2019) · Swiss Medical Weekly · doi:10.4414/smw.2019.20094 · Cited by 34
Rieckert, A., Teichmann, A.-L., Drewelow, E., Kriechmayr, C., Piccoliori, G., Woodham, A., & Sönnichsen, A. C. (2019) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocz104 · Cited by 35
Prevalence of multimorbidity among Bangladeshi adult population: a nationwide cross-sectional study
Khan, N., Rahman, M., Mitra, D. K., & Afsana, K. (2019) · BMJ Open · doi:10.1136/bmjopen-2019-030886 · Cited by 33
Hetlevik, Ø., Meland, E., Hufthammer, K. O., Breidablik, H. J., Jahanlu, D., & Vie, T. L. (2020) · SSM - Population Health · doi:10.1016/j.ssmph.2020.100604 · Cited by 33
Complex multimorbidity and mortality in Japan: a prospective propensity-matched cohort study
Kato, D., Kawachi, I. I., Saito, J., & Kondo, N. (2021) · BMJ Open · doi:10.1136/bmjopen-2020-046749 · Cited by 33
Are multimorbidity patterns associated with fear of falling in community-dwelling older adults?
Canever, J. B., Moreira, B. D. S., Danielewicz, A. L., & de Avelar, N. C. P. (2022) · BMC Geriatrics · doi:10.1186/s12877-022-02889-9 · Cited by 33
Ryu, E., Chamberlain, A. M., Pendegraft, R. S., Petterson, T. M., Bobo, W. V., & Pathak, J. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-0821-x · Cited by 33
Amell, A., Roso‐Llorach, A., Palomero, L., Cuadras, D., Galván‐Femenía, I., Serra-Musach, J., Comellas, F., de Cid, R., Pujana, M. Á., & Violán, C. (2018) · Scientific Reports · doi:10.1038/s41598-018-34361-3 · Cited by 33
Heikkilä, K., Pulakka, A., Metsälä, J., Alenius, S., Hovi, P., Gissler, M., Sandin, S., & Kajantie, E. (2021) · PLOS ONE · doi:10.1371/journal.pone.0261952 · Cited by 33
Gordon, K., Dainty, K. N., Gray, C. S., DeLacy, J., Shah, A., Resnick, M., & Seto, E. (2020) · JMIR Nursing · doi:10.2196/22118 · Cited by 32
Uhl, M. C., Muth, C., Gerlach, F. M., Schoch, G.-G., & Müller, B. S. (2018) · BMC Family Practice · doi:10.1186/s12875-017-0707-0 · Cited by 32
Self-citationLozano-Hernández, C., López-Rodríguez, J. A., Leiva-Fernández, F., Calderón‐Larrañaga, A., Cortés, J. B., Gimeno-Feliú, L. A., Poblador‐Plou, B., del Cura-González, I., & MULTIPAP GROUP (2020) · PLoS ONE · doi:10.1371/journal.pone.0235148 · Cited by 32
Multimorbidity and food insecurity in adults: A systematic review and meta-analysis
Kantilafti, M., Giannakou, K., & Chrysostomou, S. (2023) · PLoS ONE · doi:10.1371/journal.pone.0288063 · Cited by 32
Tarlovskaya, E. I. (2018) · Kardiologiia · doi:10.18087/cardio.2562 · Cited by 32
Multimorbidity at sea level and high-altitude urban and rural settings: The CRONICAS Cohort Study
Miranda, J. J., Bernabé‐Ortiz, A., Gilman, R. H., Smeeth, L. L., Málaga, G., Wise, R. A., Checkley, W., & CRONICAS Cohort Study Group (2019) · Journal of Comorbidity · doi:10.1177/2235042x19875297 · Cited by 32
Subramaniam, M., Zhang, Y., Lau, J. H., Vaingankar, J. A., Abdin, E., Chong, S. A., & Lee, E. S. (2019) · BMC Public Health · doi:10.1186/s12889-019-7941-4 · Cited by 32
Slagboom, M. N., Crone, M. R., & Reis, R. (2022) · Social Science & Medicine · doi:10.1016/j.socscimed.2020.113122 · Cited by 31
Niebuur, J., Vonk, J. M., Du, Y., de Bock, G. H., Lunter, G. A., Krabbe, P. F. M., Alizadeh, B. Z., Snieder, H., Smidt, N., Boezen, M., et al. (2023) · PLoS ONE · doi:10.1371/journal.pone.0287263 · Cited by 31
Patrones de multimorbilidad en adultos jóvenes en Cataluña: un análisis de clústeres
Violán, C., Boreu, Q. F., Roso‐Llorach, A., Rodríguez-Blanco, T., Pons‐Vigués, M., Ribera, E. P., & Valderas, J. M. (2015) · Atención Primaria · doi:10.1016/j.aprim.2015.10.006 · Cited by 31
Self-citationSchäfer, I., Kaduszkiewicz, H., Nguyen, T. S., van den Bussche, H., Scherer, M., & Schön, G. (2018) · Journal of Comorbidity · doi:10.1177/2235042x18816588 · Cited by 31
Yi, J. Y., Kim, H., & Chi, I. (2019) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/ggi.13771 · Cited by 31
Multimorbidity and healthcare resource utilization in Switzerland: a multicentre cohort study
Aubert, C. E., Fankhauser, N., Marques-Vidal, P. M., Stirnemann, J., Aujesky, D., Limacher, A., & Donzé, J. D. (2019) · BMC Health Services Research · doi:10.1186/s12913-019-4575-2 · Cited by 31
Lang, C., Voigt, K., Neumann, R., Bergmann, A., & Holthoff‐Detto, V. (2020) · Journal of Telemedicine and Telecare · doi:10.1177/1357633x20901400 · Cited by 35
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Sand, C. D., Rahbek, K., Willadsen, T. G., & Jønsson, A. B. R. (2021) · Journal of Multimorbidity and Comorbidity · doi:10.1177/26335565211009375 · Cited by 31
Dhungana, R. R., Karki, K. B., Bista, B., Pandey, A. R., Dhimal, M., & Maskey, M. K. (2021) · BMJ Open · doi:10.1136/bmjopen-2020-047665 · Cited by 31
Identifying multimorbidity clusters in an unselected population of hospitalised patients
Robertson, L. M., Vieira, R., Butler, J. E., Johnston, M. C., Sawhney, S., & Black, C. (2022) · Scientific Reports · doi:10.1038/s41598-022-08690-3 · Cited by 32
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Balakrishnan, S., Karmacharya, I., Ghimire, S., Mistry, S. K., Singh, D. R., Yadav, O. P., Gudi, N., Rawal, L. B., & Yadav, U. N. (2022) · BMC Geriatrics · doi:10.1186/s12877-022-03115-2 · Cited by 31
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Metadata
- Authors
- Violan, C., Foguet-Boreu, Q., Flores-Mateo, G., Salisbury, C., Blom, J., Freitag, M., Glynn, L., Muth, C., & Valderas, J. M.
- Affiliations
- University of Bristol (GB)
- Leiden University Medical Center (NL)
- Jena University Hospital (DE)
- Ollscoil na Gaillimhe – University of Galway (IE)
- Goethe University Frankfurt (DE)
- Corresponding author
- Salisbury, Chris
- Blom, Jeanet
- Freitag, Michael
- Glynn, Liam
- Muth, Christiane
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2014-07-21
- Volume
- 9
- Issue
- 7
- Pages
- e102149
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC4105594
- OpenAlex
- W2080696239
- Cited by
- 1,125
- References
- 59
- Citations by year
- 2026: 69 · 2025: 80 · 2024: 101 · 2023: 137 · 2022: 151 · 2021: 163 · 2020: 116 · 2019: 102 · 2018: 72 · 2017: 56 · 2016: 40 · 2015: 35 · 2014: 3
- FWCI
- 5.96
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS ONE (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Open Research Exeter (University of Exeter) (publishedVersion, other-oa)
- Explore Bristol Research (publishedVersion)
- Arrow@dit (Dublin Institute of Technology) (acceptedVersion)
- Leiden Repository (Leiden University) (submittedVersion)
- Dipòsit Digital de Documents de la UAB (Universitat Autònoma de Barcelona) (submittedVersion, cc-by)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- RePEc: Research Papers in Economics (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Figshare (submittedVersion, cc-by)
- Figshare (submittedVersion, cc-by-nc-sa)
- Publication Server of Goethe University Frankfurt am Main (Goethe University Frankfurt) (submittedVersion, cc-by)
- University of Limerick Institutional Repository (University of Limerick) (submittedVersion, cc-by-nc-sa)
- Funders
- National Institute for Health and Care Research (NIHR/CS/010/024)
- Ministerio de Ciencia e Innovación
- Topics
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Health Sciences › Medicine › Family Practice › Primary Care and Health Outcomes
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Keywords
- multimorbidity, prevalence, primary care, socioeconomic status, age, gender differences, mental illness, osteoarthritis, cardiovascular conditions, metabolic disorders
- MeSH terms
- Age Factors, Female, Humans, Male, Primary Health Care, Quality of Life, Sex Factors, Socioeconomic Factors, Comorbidity, Prevalence, Observational Studies as Topic
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