Visualization by high resolution immunoelectron microscopy of the transient receptor potential vanilloid-1 at inhibitory synapses of the mouse dentate gyrus

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

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Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

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Structure of the TRPV1 ion channel determined by electron cryo-microscopy

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TRPV1 structures in distinct conformations reveal activation mechanisms

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An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors

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The Endocannabinoid System Controls Key Epileptogenic Circuits in the Hippocampus

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Multiple Functions of Endocannabinoid Signaling in the Brain

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Endocannabinoid signaling as a synaptic circuit breaker in neurological disease

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<i>Trpv1</i> Reporter Mice Reveal Highly Restricted Brain Distribution and Functional Expression in Arteriolar Smooth Muscle Cells

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The CB1 Cannabinoid Receptor Is the Major Cannabinoid Receptor at Excitatory Presynaptic Sites in the Hippocampus and Cerebellum

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Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain

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Expression and distribution of vanilloid receptor 1 (TRPV1) in the adult rat brain

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TRPV1 Channels Mediate Long-Term Depression at Synapses on Hippocampal Interneurons

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Biochemistry and pharmacology of endovanilloids

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Reduced anxiety, conditioned fear, and hippocampal long-term potentiation in transient receptor potential vanilloid type 1 receptor-deficient mice

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Postsynaptic TRPV1 triggers cell type–specific long-term depression in the nucleus accumbens

Grueter, B. A., Brasnjo, G., & Malenka, R. C. (2010) · Nature Neuroscience · doi:10.1038/nn.2685 · Cited by 353 · see citing works

TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus

Chávez, A. E., Chiu, C. Q., & Castillo, P. E. (2010) · Nature Neuroscience · doi:10.1038/nn.2684 · Cited by 348 · see citing works

[3H]Resiniferatoxin autoradiography in the CNS of wild-type and TRPV1 null mice defines TRPV1 (VR-1) protein distribution

Roberts, J. C., Davis, J. B., & Benham, C. D. (2003) · Brain Research · doi:10.1016/j.brainres.2003.10.001 · Cited by 286 · see citing works

Hot flash: TRPV channels in the brain

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Anxiolytic Effects in Mice of a Dual Blocker of Fatty Acid Amide Hydrolase and Transient Receptor Potential Vanilloid Type-1 Channels

Micale, V., Cristino, L., Tamburella, A., Petrosino, S., Leggio, G. M., Drago, F., & Di Marzo, V. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2008.98 · Cited by 207 · see citing works

Polymodal activation of the endocannabinoid system in the extended amygdala

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The distribution and regulation of vanilloid receptor VR1 and VR1 5′ splice variant RNA expression in rat

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Existence of capsaicin-sensitive glutamatergic terminals in rat hypothalamus

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Antistress Effect of TRPV1 Channel on Synaptic Plasticity and Spatial Memory

Li, H.-B., Mao, R., Zhang, J., Yang, Y., Cao, J., & Xu, L. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.02.020 · Cited by 160 · see citing works

Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals

Nyilas, R., Dudok, B., Urbán, G. M., Mackie, K., Watanabe, M., Cravatt, B. F., Freund, T. F., & Katona, I. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.5102-07.2008 · Cited by 119 · see citing works

Immunohistochemical localization of anabolic and catabolic enzymes for anandamide and other putative endovanilloids in the hippocampus and cerebellar cortex of the mouse brain

Cristino, L., Starowicz, K., De Petrocellis, L., Morishita, J., Ueda, N., Guglielmotti, V., & Di Marzo, V. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2007.11.047 · Cited by 115 · see citing works

Localization of <i>N</i>‐acyl phosphatidylethanolamine phospholipase D (NAPE‐PLD) expression in mouse brain: A new perspective on <i>N</i>‐acylethanolamines as neural signaling molecules

Egertová, M., Simon, G. M., Cravatt, B. F., & Elphick, M. R. (2008) · Journal of Comparative Neurology · doi:10.1002/cne.21568 · Cited by 111 · see citing works

TRPV1 channels control synaptic plasticity in the developing superior colliculus

Maione, S., Cristino, L., Al, M., Georgiou, A. L., Starowicz, K., Salt, T. E., & Marzo, V. D. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2009.171900 · Cited by 88 · see citing works

TRPV1 Channels Regulate Cortical Excitability in Humans

Mori, F., Ribolsi, M., Kusayanagi, H., Monteleone, F., Mantovani, V., Buttari, F., Marasco, E., Bernardi, G., Maccarrone, M., & Centonze, D. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.2531-11.2012 · Cited by 81 · see citing works

Compartment-Specific Modulation of GABAergic Synaptic Transmission by TRPV1 Channels in the Dentate Gyrus

Chávez, A. E., Hernández, V. M., Rodenas-Ruano, A., Chan, C. S., & Castillo, P. E. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.3635-14.2014 · Cited by 59 · see citing works

The transient receptor potential vanilloid-1 is localized at excitatory synapses in the mouse dentate gyrus

Puente, N., Reguero, L., Elezgarai, I., Canduela, M. J., Mendizabal‐Zubiaga, J., Ramos, A., Fernández‐Espejo, E., & Grandes, P. (2014) · Brain Structure and Function · doi:10.1007/s00429-014-0711-2 · Cited by 33 · see citing works

Hippocampal GABAergic Inhibitory Interneurons

Pelkey, K. A., Chittajallu, R., Craig, M. T., Tricoire, L., Wester, J. C., & McBain, C. J. (2017) · Physiological Reviews · doi:10.1152/physrev.00007.2017 · Cited by 889 · see citing works

The endocannabinoid system as a target for novel anxiolytic drugs

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Suppression of Presynaptic Glutamate Release by Postsynaptic Metabotropic NMDA Receptor Signalling to Pannexin-1

Bialecki, J., Werner, A. C., Weilinger, N. L., Tucker, C. M., Vecchiarelli, H. A., Huguet, J. E., Mendizabal‐Zubiaga, J., Grandes, P., Hill, M. N., & Thompson, R. J. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.0257-19.2019 · Cited by 57 · see citing works

Insights into Potential Targets for Therapeutic Intervention in Epilepsy

Zavala‐Tecuapetla, C., Cuéllar‐Herrera, M., & Luna‐Munguía, H. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228573 · Cited by 48 · see citing works

Endocannabinoid signaling in adult hippocampal neurogenesis: A mechanistic and integrated perspective

Oddi, S., Fiorenza, M. T., & Maccarrone, M. (2023) · Progress in Lipid Research · doi:10.1016/j.plipres.2023.101239 · Cited by 26 · see citing works

Expression of TRPV1 channels by Cajal‐Retzius cells and layer‐specific modulation of synaptic transmission by capsaicin in the mouse hippocampus

Anstötz, M., Lee, S. K., & Maccaferri, G. (2018) · The Journal of Physiology · doi:10.1113/jp275685 · Cited by 19 · see citing works

Effects of Zhengtian Pills on Migraine Headache in Rats via Transient Receptor Potential Vanilloid 1

Sun, J.-H., Wang, K., Fu, H., Dai, Z., Pu, F., Yin, S., Qian, T., Liu, X., & Wang, X. (2016) · Chinese Herbal Medicines · doi:10.1016/s1674-6384(16)60049-7 · Cited by 17 · see citing works

The Absence of the Transient Receptor Potential Vanilloid 1 Directly Impacts on the Expression and Localization of the Endocannabinoid System in the Mouse Hippocampus

Huguet, J. E., Río, I. B., Gómez‐Urquijo, S., Mimenza, A., Saumell-Esnaola, M., Roman, L. B., del Caño, G. G., Sallés, J., Puente, N., Gerrikagoitia, I., et al. (2021) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2021.645940 · Cited by 16 · see citing works

Lack of the Transient Receptor Potential Vanilloid 1 Shifts Cannabinoid-Dependent Excitatory Synaptic Plasticity in the Dentate Gyrus of the Mouse Brain Hippocampus

Huguet, J. E., Saumell-Esnaola, M., Achicallende, S., Gómez, E. S., Río, I. B., del Caño, G. G., Barrondo, S., Sallés, J., Gerrikagoitia, I., Puente, N., et al. (2021) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2021.701573 · Cited by 11 · see citing works

TRPV1 regulates excitatory innervation of oriens lacunosum moleculare (OLM) neurons in the hippocampus to affect synaptic plasticity

Hurtado-Zavala, J. I. (2017) · doi:10.53846/goediss-6067

Targeting TRP channels for anxiety relief and improving mental health

SZALLASI, A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-18653-0.00009-5

The capsaicin receptor, TRPV1

SZALLASI, A. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-30202-2.00007-7

Immunoelectron Microscopy of Brain Receptors: Focus on G Protein-Coupled Receptors

Bustinza, N. P., Río, I. B., Gómez‐Urquijo, S., Gerrikagoitia, I., & Grandes, P. (2026) · Neuromethods · doi:10.1007/978-1-0716-5456-9_3

RESEARCH ARTICLE Visualization by High Resolution Immunoelectron Microscopy of the Transient Receptor Potential Vanilloid-1 at Inhibitory Synapses of the Mouse Dentate Gyrus

Miren-josune, C., Mendizabal‐Zubiaga, J., Puente, N., Reguero, L., Elezgarai, I., Ramos, A., Gerrikagoitia, I., & Gr, P. (2016)

The transient receptor potential vanilloid-1 is localized at excitatory synapses in the mouse dentate gyrus

Puente, N., Reguero, L., Elezgarai, I., Canduela, M. J., Mendizabal‐Zubiaga, J., Ramos, A., Fernández‐Espejo, E., & Grandes, P. (2014) · Brain Structure and Function · doi:10.1007/s00429-014-0711-2 · Cited by 33 · see citing works

TRPV1 regulates excitatory innervation of oriens lacunosum moleculare (OLM) neurons in the hippocampus to affect synaptic plasticity

Hurtado-Zavala, J. I. (2017) · doi:10.53846/goediss-6067

Loss of interneuron LTD and attenuated pyramidal cell LTP in Trpv1 and Trpv3 KO mice

Brown, T. E., Chirila, A. M., Schrank, B. R., & Kauer, J. A. (2013) · Hippocampus · doi:10.1002/hipo.22125 · Cited by 52 · see citing works

Inhibition of TRPV1 channels enables long-term potentiation in the entorhinal cortex

Banke, T. G. (2016) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-015-1775-4 · Cited by 9 · see citing works