Cited by 97Fibromyalgia and Chronic Fatigue Syndrome ResearchPsychosomatic Disorders and Their TreatmentsMusculoskeletal pain and rehabilitation

Three-Quarters of Persons in the US Population Reporting a Clinical Diagnosis of Fibromyalgia Do Not Satisfy Fibromyalgia Criteria: The 2012 National Health Interview Survey

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Walitt, Brian, Katz, Robert S., Bergman, Martin J., Wolfe, Frederick·2016·PLOS ONE

Abstract

OBJECTIVES: Although fibromyalgia criteria have been in effect for decades, little is known about how the fibromyalgia diagnosis is applied and understood by clinicians and patients. We used the National Health Interview Survey (NHIS) to determine the prevalence of self-reported clinician diagnosed fibromyalgia and then compared demographics, symptoms, disability and medical utilization measures of persons with a clinical diagnosis of fibromyalgia that did not meet diagnostic criteria (false-positive or prior [F/P] fibromyalgia) to persons with and without criteria-positive fibromyalgia. METHODS: The National Health Interview Survey (NHIS) collected information about both clinical diagnosis and symptoms of fibromyalgia that was appropriately weighted to represent 225,726,257 US adults. Surrogate NHIS diagnostic criteria for fibromyalgia were developed based on the level of polysymptomatic distress (PSD) as characterized in the 2011 modified American College of Rheumatology criteria (ACR) for fibromyalgia. Persons with F/P fibromyalgia were compared with persons who do not have fibromyalgia and those meeting surrogate NHIS fibromyalgia criteria. RESULTS: Of the 1.78% of persons reporting a clinical diagnosis, 73.5% did not meet NHIS fibromyalgia criteria. The prevalence of F/P fibromyalgia is 1.3%. F/P fibromyalgia is associated with a mild degree of polysymptomatic distress (NHIS PSD score 6.2) and characterized by frequent but not widespread pain and insomnia. Measures of work disability and medical utilization in F/P fibromyalgia were equal to that seen with NHIS criteria positive fibromyalgia and were 6-7x greater in F/P fibromyalgia than in non-fibromyalgia persons. F/P fibromyalgia was best predicted by being female (Odds Ratio [OR] 8.81), married (OR 3.27), and white (OR 1.96). In contrast, being a white, married woman was only modestly predictive of NHIS (criteria positive) fibromyalgia (OR 2.1). CONCLUSIONS: The majority of clinically diagnosed fibromyalgia cases in the US do not reach levels of severity necessary and sufficient for diagnosis. The clinical diagnosis of fibromyalgia is disproportionally dependent on demographic and social factors rather than the symptoms themselves. Diagnostic criteria for fibromyalgia appear to be used as a vague guide by clinicians and patients, and allow for substantial diagnostic expansion of fibromyalgia.

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  1. [2]Walitt B, Nahin, R., Katz R., Bergman M., Wolfe F. The Prevalence and Characteristics of Fibromyalgia in the 2012 National Health Interview Survey. 2015. PMC4575027 26379048
  2. [20]Walitt B, Nahin RL, Katz RS, Bergman M, Wolfe F. The Prevalence and Characteristics of Fibromyalgia in the 2012 National Health Interview Survey. PloS One. 2015. PMC4575027 26379048

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Authors
Walitt, B., Katz, R. S., Bergman, M. J., & Wolfe, F.
Affiliations
  • Georgetown University (US)
  • Rush University Medical Center (US)
  • Drexel University (US)
  • The National Databank for Rheumatic Diseases (US)
Corresponding author
Walitt, Brian
Venue
PLOS ONE
Published
2016-06-09
Volume
11
Issue
6
Pages
e0157235
ISSN
1932-6203 (ISSN-L)
OpenAlex
W2419360491
Cited by
97
References
31
Citations by year
2026: 10 · 2025: 8 · 2024: 7 · 2023: 8 · 2022: 8 · 2021: 15 · 2020: 15 · 2019: 9 · 2018: 7 · 2017: 4 · 2016: 5
FWCI
7.40
Type
journal article
Language
en
Open access
Locations
  • PLoS ONE (publishedVersion, public-domain)
  • PubMed Central (publishedVersion, public-domain)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
  • Figshare (submittedVersion, cc-by)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
  • Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
Keywords
fibromyalgia, diagnostic criteria, diagnosis, prevalence, work disability, medical utilization, insomnia, sex differences, demographic factors, ACR classification criteria, National Health Interview Survey, chronic pain, disability insurance claims, health care costs, quality of care, health care delivery, health care financing
MeSH terms
Adult, False Positive Reactions, Female, Fibromyalgia, Humans, Male, Pregnancy, United States

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