Treatment contact coverage for probable depressive and probable alcohol use disorders in four low- and middle-income country districts: the PRIME cross-sectional community surveys
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CONTEXT: A robust evidence base is now emerging that indicates that treatment for depression and alcohol use disorders (AUD) delivered in low and middle-income countries (LMIC) can be effective. However, the coverage of services for these conditions in most LMIC settings remains unknown. OBJECTIVE: To describe the methods of a repeat cross-sectional survey to determine changes in treatment contact coverage for probable depression and for probable AUD in four LMIC districts, and to present the baseline findings regarding treatment contact coverage. METHODS: Population-based cross-sectional surveys with structured questionnaires, which included validated screening tools to identify probable cases. We defined contact coverage as being the proportion of cases who sought professional help in the past 12 months. SETTING: Sodo District, Ethiopia; Sehore District, India; Chitwan District, Nepal; and Kamuli District, Uganda. PARTICIPANTS: 8036 adults residing in these districts between May 2013 and May 2014. MAIN OUTCOME MEASURES: Treatment contact coverage was defined as having sought care from a specialist, generalist, or other health care provider for symptoms related to depression or AUD. RESULTS: The proportion of adults who screened positive for depression over the past 12 months ranged from 11.2% in Nepal to 29.7% in India and treatment contact coverage over the past 12 months ranged between 8.1% in Nepal to 23.5% in India. In Ethiopia, lifetime contact coverage for probable depression was 23.7%. The proportion of adults who screened positive for AUD over the past 12 months ranged from 1.7% in Uganda to 13.9% in Ethiopia and treatment contact coverage over the past 12 months ranged from 2.8% in India to 5.1% in Nepal. In Ethiopia, lifetime contact coverage for probable AUD was 13.1%. CONCLUSIONS: Our findings are consistent with and contribute to the limited evidence base which indicates low treatment contact coverage for depression and for AUD in LMIC. The planned follow up surveys will be used to estimate the change in contact coverage coinciding with the implementation of district-level mental health care plans.
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AUD is often not detected by health care providers in sub-Saharan Africa, contributing to a wide treatment gap.
“Despite this, AUD is often not detected in health care settings, which contributes to a wide treatment gap.”
From Integration of Alcohol Use Disorder Interventions in General Health Care Settings in Sub-Saharan Africa: A Scoping Review (2022) · cites this paper as [11]
The AUD treatment gap is particularly marked in low-income and lower-middle-income countries.
“This gap is particularly marked in low-income and lower-middle-income countries (9, 11, 12).”
From Integration of Alcohol Use Disorder Interventions in General Health Care Settings in Sub-Saharan Africa: A Scoping Review (2022) · cites this paper as [11]
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Cites
The PHQ-9: Validity of a brief depression severity measure
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009606.x · Cited by 44,910 · see citing works
SAUNDERS, J. B., AASLAND, O. G., BABOR, T. F., DE LA FUENTE, J. R., & GRANT, M. (1993) · Addiction · doi:10.1111/j.1360-0443.1993.tb02093.x · Cited by 13,482 · see citing works
(1998) · PubMed · Cited by 10,216 · see citing works
Whiteford, H. A., Degenhardt, L., Rehm, J., Baxter, A. J., Ferrari, A. J., Erskine, H. E., Charlson, F. J., Norman, R. E., Flaxman, A. D., Johns, N., et al. (2013) · The Lancet · doi:10.1016/s0140-6736(13)61611-6 · Cited by 6,006 · see citing works
(2001) · Cited by 5,455 · see citing works
Rehm, J., Mathers, C., Popova, S., Thavorncharoensap, M., Teerawattananon, Y., & Patra, J. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60746-7 · Cited by 3,870 · see citing works
Ferrari, A. J., Charlson, F. J., Norman, R. E., Patten, S. B., Freedman, G., Murray, C. J. L., Vos, T., & Whiteford, H. A. (2013) · PLoS Medicine · doi:10.1371/journal.pmed.1001547 · Cited by 3,115 · see citing works
Robins, L. N. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800360017003 · Cited by 2,909 · see citing works
Sheehan, D., Lecrubier, Y., Harnett Sheehan, K., Janavs, J., Weiller, E., Keskiner, A., Schinka, J., Knapp, E., Sheehan, M., & Dunbar, G. (1997) · European Psychiatry · doi:10.1016/s0924-9338(97)83297-x · Cited by 2,149 · see citing works
Manea, L., Gilbody, S., & McMillan, D. (2012) · Canadian Medical Association Journal · doi:10.1503/cmaj.110829 · Cited by 1,966 · see citing works
(2010) · Virtual Defense Library (Ministerio de Defensa) · Cited by 1,530 · see citing works
[The national population and housing census, 2000].
Kuciarska-ciesielska, M., & Nowak, L. (1997) · PubMed · Cited by 1,410 · see citing works
A simplified general method for cluster-sample surveys of health in developing countries.
Bennett, S., Woods, T., Liyanage, W. M., & Smith, D. L. (1991) · PubMed · Cited by 862 · see citing works
Scaling Community Attitudes Toward the Mentally Ill
Taylor, S. M., & Dear, M. J. (1981) · Schizophrenia Bulletin · doi:10.1093/schbul/7.2.225 · Cited by 856 · see citing works
World Mental Health: Problems and Priorities in Low-Income Countries
Desjarlais, R., Eisenberg, L., Good, B. J., & Kleinman, A. (1995) · Cited by 750 · see citing works
De Silva, M. J., Breuer, E., Lee, L., Asher, L., Chowdhary, N., Lund, C., & Patel, V. (2014) · Trials · doi:10.1186/1745-6215-15-267 · Cited by 738 · see citing works
Self-citationCosting psychiatric interventions.
Beecham, J. K., & Knapp, M. R. J. (1992) · Kent Academic Repository (University of Kent) · Cited by 710 · see citing works
Slade, M., & Thornicroft, G. (2025) · doi:10.1093/med/9780198898818.003.0007 · Cited by 679 · see citing works
Rh, H., & Sundaresan, T. (1982) · PubMed · Cited by 612 · see citing works
Postpartum mood disorders: diagnosis and treatment guidelines.
Nonacs, R. M., & Cohen, L. S. (1998) · PubMed · Cited by 588 · see citing works
Lund, C., Tomlinson, M., De Silva, M., Fekadu, A., Shidhaye, R., Jordans, M., Petersen, I., Bhana, A., Kigozi, F., Prince, M., et al. (2012) · PLoS Medicine · doi:10.1371/journal.pmed.1001359 · Cited by 584 · see citing works
Self-citationHealth service coverage and its evaluation.
Tanahashi, T. (1978) · PubMed · Cited by 485 · see citing works
Development and psychometric properties of the Mental Health Knowledge Schedule
Evans-Lacko, S., Little, K., Meltzer, H., Rose, D., Rhydderch, D., Henderson, C., & Thornicroft, G. (2010) · The Canadian Journal of Psychiatry · doi:10.1177/070674371005500707 · Cited by 402 · see citing works
Evans-Lacko, S., Rose, D., Little, K., Flach, C., Rhydderch, D., Henderson, C., & Thornicroft, G. (2011) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796011000308 · Cited by 363 · see citing works
Hanlon, C., Luitel, N. P., Kathree, T., Murhar, V., Shrivasta, S., Medhin, G., Ssebunnya, J., Fekadu, A., Shidhaye, R., Petersen, I., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0088437 · Cited by 339 · see citing works
Self-citationGrosser, R. C. (1994) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199407000-00029 · Cited by 311 · see citing works
Williams, D. R., HERMAN, A. A. B., Stein, D. J., Heeringa, S. G., Jackson, P. B., Moomal, H., & Kessler, R. C. (2007) · Psychological Medicine · doi:10.1017/s0033291707001420 · Cited by 302 · see citing works
Kohrt, B. A., Luitel, N. P., Acharya, P., & Jordans, M. J. D. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-0768-y · Cited by 239 · see citing works
Self-citationGlobal Epidemiology of Mental Disorders: What Are We Missing?
Baxter, A. J., Patton, G. C., Scott, K. M., Degenhardt, L. J., & Whiteford, H. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065514 · Cited by 209 · see citing works
Packages of care for depression in low- and middle-income countries
Patel, V., Simon, G., Chowdhary, N., Kaaya, S., & Araya, R. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000159 · Cited by 202 · see citing works
Self-citationValidity of brief screening questionnaires to detect depression in primary care in Ethiopia
Hanlon, C., Medhin, G., Selamu, M., Breuer, E., Dubale, B. W., Hailemariam, M., Lund, C., Prince, M. J., & Fekadu, A. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.07.015 · Cited by 194 · see citing works
Self-citationLund, C., Tomlinson, M., & Patel, V. (2015) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.114.153668 · Cited by 174 · see citing works
Self-citationBerner, M. M., Kriston, L., Bentele, M., & Härter, M. C. (2007) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2007.68.461 · Cited by 164 · see citing works
Population level mental distress in rural Ethiopia
Fekadu, A., Medhin, G., Selamu, M., Hailemariam, M., Alem, A., Giorgis, T. W., Breuer, E., Lund, C., Prince, M. J., & Hanlon, C. (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-194 · Cited by 140 · see citing works
Self-citationKagee, A., Tsai, A. C., Lund, C., & Tomlinson, M. (2012) · International Health · doi:10.1093/inthealth/ihs004 · Cited by 136 · see citing works
Self-citationBreuer, E., De Silva, M. J., Shidaye, R., Petersen, I., Nakku, J., Jordans, M. J. D., Fekadu, A., & Lund, C. (2016) · British Journal of Psychiatry · doi:10.1192/bjp.bp.114.153841 · Cited by 111 · see citing works
Self-citationEstimating the coverage of mental health programmes: a systematic review
Silva, M. J. D., Lee, L., Fuhr, D. C., Rathod, S. D., Chisholm, D., Schellenberg, J., & Patel, V. (2014) · International Journal of Epidemiology · doi:10.1093/ije/dyt191 · Cited by 107 · see citing works
Self-citationEvaluation of district mental healthcare plans: The PRIME consortium methodology
De Silva, M. J., Rathod, S. D., Hanlon, C., Breuer, E., Chisholm, D., Fekadu, A., Jordans, M., Kigozi, F., Petersen, I., Shidhaye, R., et al. (2016) · British Journal of Psychiatry · doi:10.1192/bjp.bp.114.153858 · Cited by 106 · see citing works
Self-citationProcesses of Internal and International Migration from Chitwan, Nepal
Bohra, P., & Massey, D. S. (2009) · International Migration Review · doi:10.1111/j.1747-7379.2009.00779.x · Cited by 101 · see citing works
Packages of care for alcohol use disorders in low- and middle-income countries
Benegal, V., Chand, P. K., & Obot, I. S. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000170 · Cited by 94 · see citing works
Nakku, J. E. M., Rathod, S. D., Kizza, D., Breuer, E., Mutyaba, K., Baron, E. C., Ssebunnya, J., & Kigozi, F. N. (2016) · Cambridge Prisms Global Mental Health · doi:10.1017/gmh.2016.14 · Cited by 89 · see citing works
Self-citationAlcoholic beverage consumption in India, Mexico, and Nigeria: a cross-cultural comparison.
Bennett, L. A., Campillo, C., Chandrashekar, C. R., et al. (1998) · PubMed · Cited by 81 · see citing works
Setting priorities for mental health care in Nepal: a formative study
Jordans, M. J. D., Luitel, N. P., Tomlinson, M., & Komproe, I. H. (2013) · BMC Psychiatry · doi:10.1186/1471-244x-13-332 · Cited by 56 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 1
- [28]Sheehan D, Janavs J, Baker R, Harnett-Sheehan K, Knapp E, Sheehan M, et al MINI-Mini International Neuropsychiatric Interview-English Version 5.0. 0-DSM-IV. J Clin Psychiatry. 1998; 59: 34– 57. 9881538
Cited by
Sorted by citations
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Mekonen, T., Chan, G. C. K., Connor, J., Hall, W., Hides, L., & Leung, J. (2021) · Addiction · doi:10.1111/add.15357 · Cited by 207 · see citing works
Treatment gap and barriers for mental health care: a cross-sectional community survey in Nepal
Luitel, N. P., Jordans, M. J. D., Kohrt, B. A., Rathod, S. D., & Komproe, I. H. (2017) · PLOS ONE · doi:10.1371/journal.pone.0183223 · Cited by 165 · see citing works
Self-citationKohrt, B. A., Jordans, M. J. D., Turner, E. L., Sikkema, K. J., Luitel, N. P., Rai, S., Singla, D. R., Lamichhane, J., Lund, C., & Patel, V. (2018) · Pilot and Feasibility Studies · doi:10.1186/s40814-018-0234-3 · Cited by 141 · see citing works
Self-citationEstimating the global treatment rates for depression: a systematic review and meta-analysis
Mekonen, T., Chan, G. C. K., Connor, J. P., Hides, L., & Leung, J. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.09.038 · Cited by 137 · see citing works
Jordans, M. J. D., Luitel, N. P., Kohrt, B. A., Rathod, S. D., Garman, E. C., De Silva, M., Komproe, I. H., Patel, V., & Lund, C. (2019) · PLOS Medicine · doi:10.1371/journal.pmed.1002748 · Cited by 104 · see citing works
Self-citationTreatment gap, help-seeking, stigma and magnitude of alcohol use disorder in rural Ethiopia
Zewdu, S., Hanlon, C., Fekadu, A., Medhin, G., & Teferra, S. (2019) · Substance Abuse Treatment, Prevention, and Policy · doi:10.1186/s13011-019-0192-7 · Cited by 110 · see citing works
Self-citationJordans, M. J. D., Luitel, N. P., Garman, E., Kohrt, B. A., Rathod, S. D., Shrestha, P., Komproe, I. H., Lund, C., & Patel, V. (2019) · British Journal of Psychiatry · doi:10.1192/bjp.2018.300 · Cited by 89 · see citing works
Self-citationLuitel, N. P., Baron, E. C., Kohrt, B. A., Komproe, I. H., & Jordans, M. J. D. (2018) · BMC Health Services Research · doi:10.1186/s12913-018-3034-9 · Cited by 36 · see citing works
Self-citationClosing the treatment gap for alcohol use disorders in low- and middle-income countries
Nadkarni, A., Gandhi, Y., Bhatia, U., & Velleman, R. (2023) · Cambridge Prisms: Global Mental Health · doi:10.1017/gmh.2022.57 · Cited by 46 · see citing works
Preusse, M., Neuner, F., & Ertl, V. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00768 · Cited by 38 · see citing works
Mushi, D., Moshiro, C., Hanlon, C., Francis, J. M., & Teferra, S. (2022) · Substance Abuse Treatment, Prevention, and Policy · doi:10.1186/s13011-022-00479-x · Cited by 32 · see citing works
Danpanichkul, P., Suparan, K., Ng, C. H., Dejvajara, D., Kongarin, S., Panpradist, N., Chaiyakunapruk, N., Muthiah, M. D., Chen, V. L., Huang, D. Q., et al. (2024) · JHEP Reports · doi:10.1016/j.jhepr.2024.101020 · Cited by 37 · see citing works
Mushi, D., Francis, J. M., Moshiro, C., Hanlon, C., & Teferra, S. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.822791 · Cited by 21 · see citing works
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- Authors
- Rathod, S. D., De Silva, M. J., Ssebunnya, J., Breuer, E., Murhar, V., Luitel, N. P., Medhin, G., Kigozi, F., Shidhaye, R., Fekadu, A., Jordans, M., Patel, V., Tomlinson, M., & Lund, C.
- Affiliations
- London School of Hygiene & Tropical Medicine (GB)
- Butabika Hospital (UG)
- University of Cape Town (ZA)
- Sangath (IN)
- Addis Ababa University (ET)
- Maastricht University (NL)
- King's College London (GB)
- Corresponding author
- Rathod, Sujit D.
- ORCID
- Venue
- PLOS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2016-09-15
- Volume
- 11
- Issue
- 9
- Pages
- e0162038
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC5025033
- OpenAlex
- W2521034821
- Cited by
- 103
- References
- 44
- Citations by year
- 2026: 3 · 2025: 8 · 2024: 12 · 2023: 28 · 2022: 8 · 2021: 10 · 2020: 13 · 2019: 10 · 2018: 8 · 2017: 3
- FWCI
- 11.01
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS ONE (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Research Publications (Maastricht University) (publishedVersion, cc-by)
- LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Open University of Cape Town (University of Cape Town) (submittedVersion, cc-by)
- SUNScholar (Stellenbosch University) (submittedVersion)
- Research Publications (Maastricht University) (submittedVersion, other-oa)
- Greater South Information System
- Funders
- Department for International Development (201446)
- National Research Foundation (ECR151130156234)
- Topics
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- depression, alcoholism, mental health service utilization, low- and middle-income countries, help-seeking, mental health service planning, PRIME study, Ethiopia, India, Nepal, Uganda
- MeSH terms
- Adult, Cross-Sectional Studies, Depression, Ethiopia, Female, Humans, India, Male, Middle Aged, Nepal, Surveys and Questionnaires, South Africa, Uganda, Alcohol-Related Disorders
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