The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Exponential increase in mortality with age is a generic property of a simple model system of damage accumulation and death
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Another recent stochastic damage accumulation model based on queue theory provides a similar framework for the Gompertz law.
“Another recent stochastic damage accumulation model based on queue theory provides a similar framework for the Gompertz law24.”
From A damage accumulation model identifies distinct aging regimes across species (2026) · cites this paper as [24]
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López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013) · Cell · doi:10.1016/j.cell.2013.05.039 · Cited by 14,982
Gompertz, B. (1825) · Philosophical Transactions of the Royal Society of London · doi:10.1098/rstl.1825.0026 · Cited by 3,816
Herskind, A. M., McGue, M., Holm, N. V., Sørensen, T. I. A., Harvald, B., & Vaupel, J. W. (1996) · Human Genetics · doi:10.1007/bf02185763 · Cited by 879
DNA repair and aging: The impact of the p53 family
Nicolai, S., Rossi, A., Di Daniele, N., Melino, G., Annicchiarico-Petruzzelli, M., & Raschellà, G. (2015) · Aging · doi:10.18632/aging.100858 · Cited by 118
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Research works printed but not linked: 33
- A Comfort, 1964, Time, Cells, and aging
- BL Strehler, 1977, Time, Cells, and aging
- S Olshansky, 1997, Ever since Gompertz, Demography, 34, 1, 10.2307/2061656 · DOI
- TBL Kirkwood, 2015, Deciphering death: a commentary on Gompertz (1825) ‘On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies’, Philos Trans R Soc B, 370
- TE Johnson, 1990, Increased Life-Span of age-I Mutants in Caenorhabditis elegans and Lower Gompertz Rate of Aging, Science, 249, 908, 10.1126/science.2392681 · DOI
- Statistics Sweden. Cohort mortality in Sweden. Mortality statistics since 1861; 2010. · DOI
- T Kirkwood, 2005, Understanding the odd science of aging, Cell, 120, 437, 10.1016/j.cell.2005.01.027 · DOI · Paper page
- A Mitnitski, 2015, Aging and Health—A Systems Biology Perspective, 85, 10.1159/000364933 · DOI · Paper page
- M Ogrodnik, 2019, Integrating cellular senescence with the concept of damage accumulation in aging: Relevance for clearance of senescent cells, Aging Cell, 18, 10.1111/acel.12841 · DOI · Paper page
- V Gorbunova, 2007, Changes in DNA repair during aging, Nucleic Acids Res, 35, 7466, 10.1093/nar/gkm756 · DOI · Paper page
- D Gross, 2008, Fundamentals of Queueing Theory, 10.1002/9781118625651 · DOI
- J Abate, 1987, Transient behavior of the M/M/1 queue: starting at the origin, Queuing Syst, 2, 41, 10.1007/BF01182933 · DOI
- JD Kalbfleisch, 2002, The Statistical Analysis Failure Time Data, 10.1002/9781118032985 · DOI · Paper page
- G Newell, 1982, Applications of Queueing Theory, 10.1007/978-94-009-5970-5 · DOI
- J Vaupel, 1979, Impact Of Heterogeneity In Individual Frailty On The Dynamics Of Mortality, Demography, 16, 439, 10.2307/2061224 · DOI · Paper page
- JW Vaupel, 2014, Unobserved population heterogeneity: A review of formal relationships, Demogr Res, 31, 659, 10.4054/DemRes.2014.31.22 · DOI
- A Yashin, 1994, A Duality In Aging—The Equivalence Of Mortality Models Based On Radically Different Concepts, Mech Ageing Dev, 74, 1, 10.1016/0047-6374(94)90094-9 · DOI
- E Hemminki, 1976, The Effect of Antibiotics on Mortality From Infectious Diseases In Sweden and Finland, Am J Public Health, 66, 1180, 10.2105/AJPH.66.12.1180 · DOI
- LA Gavrilov, 2019, New Trend in Old-Age Mortality: Gompertzialization of Mortality Trajectory, Gerontology, 65, 451, 10.1159/000500141 · DOI
- B Strehler, 1960, General Theory Of Mortality And Aging, Science, 132, 14, 10.1126/science.132.3418.14 · DOI · Paper page
- O Burger, 2016, Evolutionary theory of ageing and the problem of correlated Gompertz parameters, J Theor Biol, 408, 34, 10.1016/j.jtbi.2016.08.002 · DOI
- G Newell, 1968, Queues With Time-Dependent Arrival Rates. I. Transition Through Saturation, J Appl Probab, 5, 436, 10.2307/3212264 · DOI
- R Rau, 2007, Seasonality in Human Mortality: A Demographic Approach
- Ledberg A. A large decrease in the magnitude of seasonal fluctuations in mortality explains part of the increase in longevity in Sweden during the 20th century. medRxiv. 2020. · DOI
- J Hjelmborg, 2006, Genetic influence on human lifespan and longevity, Human Genetics, 119, 312, 10.1007/s00439-006-0144-y · DOI
- G Sacher, 1962, Stochastic Theory Of Mortality, Ann N Y Acad Sci, 96, 985, 10.1111/j.1749-6632.1962.tb54116.x · DOI
- K Brown, 1974, Mathematical-Model Of Aging Processes, J Gerontol, 29, 46, 10.1093/geronj/29.1.46 · DOI
- M Woodbury, 1977, Random-Walk Model Of Human Mortality And Aging, Theor Popul Biol, 11, 37, 10.1016/0040-5809(77)90005-3 · DOI
- AC Economos, 1982, Rate of aging, rate of dying and the mechanism of mortality, Arch Gerontol Geriatr, 1, 3, 10.1016/0167-4943(82)90003-6 · DOI
- L Gavrilov, 2001, The reliability theory of aging and longevity, J Theor Biol, 213, 527, 10.1006/jtbi.2001.2430 · DOI · Paper page
- A Mitnitski, 2005, Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality, J Am Geriatr Soc, 53, 2184, 10.1111/j.1532-5415.2005.00506.x · DOI · Paper page
- K Rockwood, 2005, A global clinical measure of fitness and frailty in elderly people, Can Med Assoc J, 173, 489, 10.1503/cmaj.050051 · DOI · Paper page
- A Mitnitski, 2013, Assessing biological aging: the origin of deficit accumulation, Biogerontology, 14, 709, 10.1007/s10522-013-9446-3 · DOI · Paper page
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A damage accumulation model identifies distinct aging regimes across species
Raz, N., Yang, Y., Pridham, G., Shenhar, B., Frenkel, S., Levy, T., Tlusty, T., Mayo, A., & Alon, U. (2026) · Nature Aging · doi:10.1038/s43587-026-01138-7 · Cited by 7
Metadata
- Authors
- Ledberg, A.
- ORCID
- Ledberg, Anders
- Venue
- PLOS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2020-06-04
- Volume
- 15
- Issue
- 6
- Pages
- e0233384
- ISSN
- 1932-6203
- PMC
- PMC7272078
- Cited by
- 29
- References
- 4
- Language
- en
- Funders
- Statens institutionsstyrelse (2.6.1-1134-2017)
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