Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection

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1. Fatigue following COVID-19 infection is not associated with autonomic dysfunction
   Liam Townsend, David J. Moloney, Ciarán Finucane, Kevin McCarthy, Colm J Bergin, Ciarán Bannan, Rose Anne Kenny · 2021 · PLoS ONE
2. Determinants of persistence of symptoms and impact on physical and mental wellbeing in Long COVID: A prospective cohort study
   Elda Righi, Massimo Mirandola, Fulvia Mazzaferri, Giuditta Dossi, Elisa Razzaboni, Amina Zaffagnini, Federico Ivaldi, Alessandro Visentin, Lorenza Lambertenghi, Cinzia Arena et al. · 2022 · Journal of Infection
3. Long COVID-19—it's not over until?
   Dana Yelin, Ili Margalit, Dafna Yahav, Michael Runold, Judith Bruchfeld · 2020 · Clinical Microbiology and Infection
4. More than 50 Long-Term Effects of COVID-19: A Systematic Review and Meta-Analysis
   Sandra López‐León, Talía Wegman-Ostrosky, Carol Perelman, Rosalinda Sepúlveda, Paulina A. Rebolledo, Angélica Cuapio, Sonia Villapol · 2021 · SSRN Electronic Journal
5. A Paradigm for Post-Covid-19 Fatigue Syndrome Analogous to ME/CFS
   Angus V. P. Mackay · 2021 · Frontiers in Neurology
6. Comprehensive Clinical Characterisation of Brain Fog in Adults Reporting Long COVID Symptoms
   Glenn Jennings, Ann Monaghan, Xue Feng, Eoin Duggan, Román Romero‐Ortuño · 2022 · Journal of Clinical Medicine
7. Intracortical GABAergic dysfunction in patients with fatigue and dysexecutive syndrome after COVID-19
   Viviana Versace, Luca Sebastianelli, Davide Ferrazzoli, Roberto Romanello, Paola Ortelli, Leopold LS. Saltuari, Alessia D’Acunto, Francesco Porrazzini, Valentina Ajello, Antonio Oliviero et al. · 2021 · Clinical Neurophysiology
8. 'Reluctant pioneer': A qualitative study of doctors' experiences as patients with long COVID
   Anna Kathryn Taylor, Tom Kingstone, Tracy Ann Briggs, Catherine A. O’Donnell, Helen Atherton, David Blane, Carolyn Anne Chew-Graham · 2021 · Health Expectations
9. Long COVID occurrence in COVID-19 survivors
   Aya Sugiyama, Kei Miwata, Yoshihiro Kitahara, Mafumi Okimoto, Kanon Abe, E Bunthen, Serge Ouoba, Tomoyuki Akita, Naoki Tanimine, Hideki Ohdan et al. · 2022 · Scientific Reports
10. Characteristics of long-COVID among older adults: a cross-sectional study
    Vered Daitch, Dana Yelin, Muhammad Awwad, Giovanni Guaraldi, Jovana Milić, Cristina Mussini, Marco Falcone, Giusy Tiseo, Laura Carrozzi, Francesco Pistelli et al. · 2022 · International Journal of Infectious Diseases
11. Post-Acute Sequelae of COVID-19 and Cardiovascular Autonomic Dysfunction: What Do We Know?
    Bisaccia, Giandomenico, Ricci, Fabrizio, Recce, Vittoria, Serio, Antonio, Iannetti, Giovanni, Chahal, Anwar A., Ståhlberg, Marcus, Khanji, Mohammed Yunus, Fedorowski, Artur, Gallina, Sabina · 2021 · Journal of Cardiovascular Development and Disease
12. Severe Fatigue and Persistent Symptoms at 3 Months Following Severe Acute Respiratory Syndrome Coronavirus 2 Infections During the Pre-Delta, Delta, and Omicron Time Periods: A Multicenter Prospective Cohort Study
    Michael A. Gottlieb, Ralph C. Wang, Huihui Yu, Erica Sarah Spatz, Juan Carlos C. Montoy, Robert M. Rodriguez, Anna Marie Chang, Joann G. Elmore, Paavali A. Hannikainen, Mandy J. Hill et al. · 2023 · Clinical Infectious Diseases
13. Persistent COVID-19 Symptoms at 6 Months After Onset and the Role of Vaccination Before or After SARS-CoV-2 Infection
    Stephanie A Richard, Simon D. Pollett, Anthony C Fries, Catherine M Berjohn, Ryan C. Maves, Tahaniyat Lalani, Alfred Glaze Smith, Rupal M. Mody, Anuradha Ganesan, Rhonda E Colombo et al. · 2023 · JAMA Network Open
14. Altered motor cortex physiology and dysexecutive syndrome in patients with fatigue and cognitive difficulties after mild COVID-19
    Ortelli, Paola, Ferrazzoli, Davide, Sebastianelli, Luca, Maestri, Roberto, Dezi, Sabrina, Spampinato, Danny, Saltuari, Leopold, Alibardi, Alessia, Engl, Michael, Kofler, Markus et al. · 2022 · European Journal of Neurology
15. Long COVID: Association of Functional Autoantibodies against G-Protein-Coupled Receptors with an Impaired Retinal Microcirculation
    Charlotte Szewczykowski, Christian Yahya Mardin, Marianna Lucio, Gerd Wallukat, Jakob Hoffmanns, Thora Schröder, Franziska Raith, Lennart Rogge, Felix Heltmann, Michael Moritz et al. · 2022 · International Journal of Molecular Sciences
16. Safety and efficacy of low dose naltrexone in a long covid cohort; an interventional pre-post study
    Brendan O’Kelly, Louise Vidal, Tina McHugh, James Woo, Gordana Avramovic, John Shearer Lambert · 2022 · Brain Behavior & Immunity - Health
17. Immunofibrotic drivers of impaired lung function in postacute sequelae of SARS-CoV-2 infection
    Hyung J. Chun, Elias E. Coutavas, Alexander B. Pine, Alfred Ian Lee, Vanessa Yu, Marcus Shallow, Coral X. Giovacchini, Anne M. Mathews, Brian Stephenson, Loretta G. Que et al. · 2021 · JCI Insight
18. Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection
    David H. Jiang, Darius Jake Roy, Brett Gu, Leslie C. Hassett, Rozalina G. McCoy · 2021 · JACC Basic to Translational Science
19. The impact of Post-COVID-Syndrome on functioning – results from a community survey in patients after mild and moderate SARS-CoV-2-infections in Germany
    Christina Lemhöfer, Christian Sturm, Dana Loudovici-Krug, Norman Best, Christoph M. Gutenbrunner · 2021 · Journal of Occupational Medicine and Toxicology
20. Functionality, physical activity, fatigue and quality of life in patients with acute COVID-19 and Long COVID infection
    Rodrigo Vélez-Santamaría, Jessica Fernández-Solana, Fátima Méndez-López, Marta Domínguez García, Jeronimo Javier Gonzalez-Bernal, Rosa Mª Magallón-Botaya, Bárbara Oliván‐Blázquez, Josefa González‐Santos, Mirian Santamaría‐Peláez · 2023 · Scientific Reports
21. Role of SARS-CoV-2 Spike-Protein-Induced Activation of Microglia and Mast Cells in the Pathogenesis of Neuro-COVID
    Theoharis Constantin Theoharides, Duraisamy Kempuraj · 2023 · Cells
22. Chronic fatigue syndrome: an emerging sequela in COVID-19 survivors?
    Elisa Mantovani, Sara Mariotto, Daniele Gabbiani, Gianluigi Dorelli, Silvia Bozzetti, Angela Federico, Serena Zanzoni, Domenico Girelli, Ernesto Crisafulli, Sérgio Ferrari et al. · 2021 · Journal of NeuroVirology
23. Adolescent and Young Adult ME/CFS After Confirmed or Probable COVID-19
    Lindsay S. Petracek, Stacy J. Suskauer, Rebecca F. Vickers, Neel Patel, Richard L. Violand, Renee L. Swope, Peter C. Rowe · 2021 · Frontiers in Medicine
24. Severe Fatigue in Long COVID: Web-Based Quantitative Follow-up Study in Members of Online Long COVID Support Groups
    Maarten Van Herck, Yvonne M.J. Goërtz, Sarah Houben‐Wilke, Felipe Vilaça Cavallari Machado, Roy Meys, Jeannet M. Delbressine, Anouk W. Vaes, Chris Burtin, Rein Posthuma, Frits M.E. Franssen et al. · 2021 · Journal of Medical Internet Research
25. Molecular Imaging Findings on Acute and Long-Term Effects of COVID-19 on the Brain: A Systematic Review
    Philipp Tobias Meyer, Sabine Hellwig, Ganna Blazhenets, Jonas A. Hosp · 2022 · Journal of Nuclear Medicine
26. Post‑COVID‑19 Syndrome in Outpatients: A Cohort Study
    Florian Desgranges, Eliana Tadini, Aline Munting, Jean Regina, Paraskevas Filippidis, Benjamin Viala, Eleftherios Karachalias, Véronique Suttels, David Haefliger, Eleftheria Kampouri et al. · 2021 · Journal of General Internal Medicine
27. Sustained VWF-ADAMTS-13 axis imbalance and endotheliopathy in long COVID syndrome is related to immune dysfunction
    Helen Fogarty, Soracha E. Ward, Liam Townsend, Ellie Karampini, Stephanie Elliott, Niall P. Conlon, Jean Dunne, Rachel Kiersey, Aifric Naughton, Mary Gardiner et al. · 2022 · Journal of Thrombosis and Haemostasis
28. The Sexual Long COVID (SLC): Erectile Dysfunction as a Biomarker of Systemic Complications for COVID-19 Long Haulers
    Andrea Sansone, Daniele Mollaioli, Erika Limoncin, Giacomo Ciocca, Nguyễn Hoài Bắc, Nguyễn Cao Thắng, Guangdong Hou, Jianlin Yuan, Michael Zitzmann, Annamaria G Elena Giraldi et al. · 2021 · Sexual Medicine Reviews
29. Long term predictors of breathlessness, exercise intolerance, chronic fatigue and well-being in hospitalized patients with COVID-19: A cohort study with 4 months median follow-up
    Imad M. Tleyjeh, Basema Ahmad Saddik, Rakhee Kizhuvappat Ramakrishnan, Nourah AlSwaidan, Ahmed S. Alanazi, Deema Alhazmi, Ahmad Aloufi, Fahad AlSumait, Elie F. Berbari, Rabih Halwani · 2021 · Journal of Infection and Public Health
30. Mental Health in Times of the COVID-19 Pandemic
    Janine Wirkner, Hanna Christiansen, Christine Knaevelsrud, Ulrike Lüken, Susanne Wurm, Silvia Schneider, Eva‐Lotta Brakemeier · 2021 · European Psychologist
31. Prevalence, trajectory over time, and risk factor of post-COVID-19 fatigue
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32. Persistence of COVID-19 Symptoms after Recovery in Mexican Population
    Carlos Eric Galvan-Tejada, Cintya Fabiola Herrera-García, Susana Godina-González, Karen E. Villagrana-Bañuelos, Juan Daniel De Luna Amaro, Karla Herrera-García, Carolina Rodríguez-Quiñones, Laura A. Zanella-Calzada, Julio Ramírez-Barranco, Jocelyn L. Ruiz de Avila et al. · 2020 · International Journal of Environmental Research and Public Health
33. Post–COVID-19 Syndrome: Theoretical Basis, Identification, and Management
    Kristine Anne Scordo, Misty M. Richmond, Nancy Munro · 2021 · AACN Advanced Critical Care
34. Preliminary Guidelines for the Clinical Evaluation and Management of Long COVID
    Yoonjung Kim, Seong Eun Kim, Tark Kim, Ki Wook Yun, So Hee Lee, Eun Jung Lee, Jun-Won Seo, Young Hee Jung, Yong Pil Chong · 2022 · Infection and Chemotherapy
35. Fatigue outcomes following COVID-19: a systematic review and meta-analysis
    Kim Poole-Wright, Ismail Guennouni, Olivia Sterry, Rachael A Evans, Fiona Gaughran, Trudie Chalder · 2023 · BMJ Open
36. A Randomized Controlled Trial of the Efficacy of Systemic Enzymes and Probiotics in the Resolution of Post-COVID Fatigue
    Rathi, Abhijit, Jadhav, Swati B., Shah, Neha · 2021 · Medicines
37. Long COVID: Clinical characteristics, proposed pathogenesis and potential therapeutic targets
    Grace Kenny, Liam Townsend, Stefano Savinelli, Patrick W. G. Mallon · 2023 · Frontiers in Molecular Biosciences
38. Long COVID, the Brain, Nerves, and Cognitive Function
    Allison Bethanne Reiss, Caitriona Greene, Christopher Dayaramani, Steven H. Rauchman, Mark M. Stecker, Joshua De Leon, Aaron Pinkhasov · 2023 · Neurology International
39. High prevalence of post COVID-19 fatigue in patients with type 2 diabetes: A case-control study
    Juhi Mittal, Amerta Ghosh, Surya Prakash Bhatt, Shajith Anoop S, Irshad Ahmad Ansari, Anoop Misra · 2021 · Diabetes & Metabolic Syndrome Clinical Research & Reviews
40. Post-viral fatigue in COVID-19: A review of symptom assessment methods, mental, cognitive, and physical impairment
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41. Risk Predictors and Symptom Features of Long COVID Within a Broad Primary Care Patient Population Including Both Tested and Untested Patients
    Rupert C. M. Jones, Andrew Davis, Brooklyn O. C. Stanley, Steven A. Julious, Dermot P. Ryan, David J. Jackson, David M.G. Halpin, Katherine Hickman, Hilary Pinnock, Jennifer Kathleen Quint et al. · 2021 · Pragmatic and Observational Research
42. Patterns of Long COVID Symptoms: A Multi-Center Cross Sectional Study
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43. Evaluating fatigue in patients recovering from COVID-19: validation of the fatigue severity scale and single item screening questions
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44. Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study
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45. Anxiety, depression, insomnia, and trauma-related symptoms following COVID-19 infection at long-term follow-up
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46. The efficacy of curcumin-piperine co-supplementation on clinical symptoms, duration, severity, and inflammatory factors in COVID-19 outpatients: a randomized double-blind, placebo-controlled trial
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48. Fatigue, perceived stigma, self-reported cognitive deficits and psychological morbidity in patients recovered from COVID-19 infection
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49. Molecular Hydrogen Positively Affects Physical and Respiratory Function in Acute Post-COVID-19 Patients: A New Perspective in Rehabilitation
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50. New‐onset and persistent neurological and psychiatric sequelae of COVID‐19 compared to influenza: A retrospective cohort study in a large New York City healthcare network
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51. Exercise Pathophysiology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Postacute Sequelae of SARS-CoV-2
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52. Deep Phenotyping of Neurologic Postacute Sequelae of SARS-CoV-2 Infection
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53. A cardiovascular magnetic resonance imaging-based pilot study to assess coronary microvascular disease in COVID-19 patients
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54. A comparison of pain, fatigue, and function between post–COVID-19 condition, fibromyalgia, and chronic fatigue syndrome: a survey study
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56. Longitudinal Analysis of COVID-19 Patients Shows Age-Associated T Cell Changes Independent of Ongoing Ill-Health
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57. Long COVID Symptomatology After 12 Months and Its Impact on Quality of Life According to Initial Coronavirus Disease 2019 Disease Severity
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58. Rehabilitation and COVID-19: a rapid living systematic review by Cochrane Rehabilitation Field updated as of December 31st, 2020 and synthesis of the scientific literature of 2020
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59. Feasibility of an Outpatient Training Program after COVID-19
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60. Brain microstructural changes and fatigue after COVID-19
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61. Addressing Post-COVID Symptoms: A Guide for Primary Care Physicians
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62. Associations of subjective and objective cognitive functioning after COVID-19: A six-month follow-up of ICU, ward, and home-isolated patients
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63. Mast cells in the autonomic nervous system and potential role in disorders with dysautonomia and neuroinflammation
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64. Infection with SARS-CoV-2 Variants Is Associated with Different Long COVID Phenotypes
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65. Prevalence and risk factors for long COVID after mild disease: A cohort study with a symptomatic control group
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66. Postural balance and its association with functionality and quality of life in non‐hospitalized patients with post‐acute COVID‐19 syndrome
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67. Positive Impacts of a Four-Week Neuro-Meditation Program on Cognitive Function in Post-Acute Sequelae of COVID-19 Patients: A Randomized Controlled Trial
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68. Chronic fatigue syndrome and cognitive deficit are associated with acute-phase neuropsychiatric manifestations of COVID-19: A 9-month follow-up study
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69. The Impact of the COVID-19 Pandemic on Dementia Risk: Potential Pathways to Cognitive Decline
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70. Fatigue Symptoms Associated With COVID-19 in Convalescent or Recovered COVID-19 Patients; a Systematic Review and Meta-Analysis
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71. Two-Years Follow-Up of Symptoms and Return to Work in Complex Post-COVID-19 Patients
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72. Multidisciplinary outpatient rehabilitation of physical and neurological sequelae and persistent symptoms of covid-19: a prospective, observational cohort study
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73. Long COVID a New Derivative in the Chaos of SARS-CoV-2 Infection: The Emergent Pandemic?
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74. Pain Burden in Post-COVID-19 Syndrome following Mild COVID-19 Infection
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75. Cardiac MRI in Patients with Prolonged Cardiorespiratory Symptoms after Mild to Moderate COVID-19
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76. Long COVID as a functional somatic symptom disorder caused by abnormally precise prior expectations during Bayesian perceptual processing: A new hypothesis and implications for pandemic response
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77. COVID-19 and Cardiac Arrhythmias: a Contemporary Review
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78. Variability in Forest Visit Numbers in Different Regions and Population Segments before and during the COVID-19 Pandemic
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79. Deep Dive into the Long Haul: Analysis of Symptom Clusters and Risk Factors for Post-Acute Sequelae of COVID-19 to Inform Clinical Care
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80. Self-scored impairments in functioning and disability in post-COVID syndrome following mild COVID-19 infection
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81. Global prevalence of persistent neuromuscular symptoms and the possible pathomechanisms in COVID-19 recovered individuals: A systematic review and meta-analysis
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82. Local anesthetics as a therapeutic tool for post COVID-19 patients: A case report
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83. Secuelas médicas de la COVID-19
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84. Observational study on the benefit of a nutritional supplement, supporting immune function and energy metabolism, on chronic fatigue associated with the SARS-CoV-2 post-infection progress
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85. Do Anxiety and Depression Predict Persistent Physical Symptoms After a Severe COVID-19 Episode? A Prospective Study
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86. Prevalence of depression in SARS-CoV-2 infected patients: An umbrella review of meta-analyses
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87. Pain Management in the Post-COVID Era—An Update: A Narrative Review
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88. Clustering Analysis Identified Three Long COVID Phenotypes and Their Association with General Health Status and Working Ability
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89. Investigating the Relationship between Vitamin D and Persistent Symptoms Following SARS-CoV-2 Infection
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90. Leitlinie S1: Long COVID: Differenzialdiagnostik und Behandlungsstrategien
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91. COVID-19: A Redox Disease—What a Stress Pandemic Can Teach Us About Resilience and What We May Learn from the Reactive Species Interactome About Its Treatment
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92. Immunological Mechanisms of Sickness Behavior in Viral Infection
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93. Long-term cognitive impairments following COVID-19: a possible impact of hypoxia
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94. Long-Term Neurological Sequelae Among Severe COVID-19 Patients: A Systematic Review and Meta-Analysis
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