Cited by 200Workplace Violence and BullyingPsychiatric care and mental health servicesHealthcare Decision-Making and Restraints

The DOI matches its Crossref record; 181 of the 181 references it cites were found in a registry or an index.

Aggression on the psychiatric ward: Prevalence and risk factors. A systematic review of the literature

Open access

Abstract

Introduction: On psychiatric wards, aggressive behaviour displayed by patients is common and problematic. Understanding factors associated with the development of aggression offers possibilities for prevention and targeted interventions. This review discusses factors that contribute to the development of aggression on psychiatric wards. Method: In Pubmed and Embase, a search was performed aimed at: prevalence data, ward characteristics, patient and staff factors that are associated with aggressive behaviour and from this search 146 studies were included. Results: The prevalence of aggressive behaviour on psychiatric wards varied (8–76%). Explanatory factors of aggressive behaviour were subdivided into patient, staff and ward factors. Patient risk factors were diagnosis of psychotic disorder or bipolar disorder, substance abuse, a history of aggression, younger age. Staff risk factors included male gender, unqualified or temporary staff, job strain, dissatisfaction with the job or management, burn-out and quality of the interaction between patients and staff. Staff protective factors were a good functioning team, good leadership and being involved in treatment decisions. Significant ward risk factors were a higher bed occupancy, busy places on the ward, walking rounds, an unsafe environment, a restrictive environment, lack of structure in the day, smoking and lack of privacy. Conclusion: Despite a lack of prospective quantitative data, results did show that aggression arises from a combination of patient factors, staff factors and ward factors. Patient factors were studied most often, however, besides treatment, offering the least possibilities in prevention of aggression development. Future studies should focus more on the earlier stages of aggression such as agitation and on factors that are better suited for preventing aggression such as ward and staff factors. Management and clinicians could adapt staffing and ward in line with these results.

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Crossref · 10.1371/journal.pone.0258346

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  • One probable link between smoking and ASB is attributed to the influence of nicotine on the CNS via exaggerated stress sensitivity and changed epigenetic regulation.

    “One of the probable links between smoking and ASB is attributed to the influence of nicotine on the CNS via exaggerated stress sensitivity (Weltens et al., 2021) and changed in epigenetic regulation (Gould et al., 2023).”

    From Using polygenic scores to assess liability to antisocial behavior (2025) · cites this paper as Weltens et al., 2021

    The Results sections on patient and ward factors report associations between cigarette craving, smoking-related ward conditions, and aggression. They do not explain the link through nicotine’s effects on the CNS or exaggerated stress sensitivity. The epigenetic-regulation clause is attributed to a different citation and is not assessed here; page numbers were unavailable in our copy. (LLM, conf=0.82)

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Research works printed but not linked: 2

  1. Merriam Webster Dictionary, 2008, Merriam Webster US
  2. JM Johnson, 2015, The effects of cannabis on inpatient agitation, aggression, and length-of-stay in patients with schizophrenia, schizoaffective disorder, and bipolar disorder, Journal of Pharmacy Practice, 28, 329

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Metadata

Authors
Weltens, I., Bak, M., Verhagen, S., Vandenberk, E., Domen, P., van Amelsvoort, T., & Drukker, M.
Affiliations
Maastricht University (NL)
Corresponding author
Weltens, Irene
Venue
PLOS ONE
Published
2021-10-08
Volume
16
Issue
10
Pages
e0258346
ISSN
1932-6203 (ISSN-L)
OpenAlex
W3203779517
Cited by
200
References
181
Citations by year
2026: 53 · 2025: 58 · 2024: 29 · 2023: 40 · 2022: 18 · 2021: 2
FWCI
4.27
Type
journal article
Language
en
Open access
Locations
  • PLoS ONE (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, other-oa)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Research Publications (Maastricht University) (publishedVersion, cc-by)
  • DSpace (Open University in the Netherlands) (publishedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • DSpace (Open University in the Netherlands) (submittedVersion, other-oa)
  • Research Publications (Maastricht University) (submittedVersion, other-oa)
Topics
  • Social Sciences › Business, Management and Accounting › Organizational Behavior and Human Resource Management › Workplace Violence and Bullying
  • Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
  • Social Sciences › Psychology › Clinical Psychology › Healthcare Decision-Making and Restraints
Keywords
aggression, psychiatric ward, prevalence, risk factors, patient factors, ward environment, psychosis, bipolar disorder, substance abuse, job strain, staff-patient interaction, aggression prevention
MeSH terms
Aggression, Bed Occupancy, Female, Health Personnel, Humans, Male, Mental Health, Psychiatric Department, Hospital, Risk Factors, Time Factors, Violence, Prevalence, Substance-Related Disorders

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