Estimating The Health And Economic Burden Of Cancer Among Those Diagnosed As Adolescents And Young Adults
Open accessAbstract
Adolescent and young adult cancer survivors-those who were ages 15-39 at their first cancer diagnosis-have important health limitations. These survivors are at risk for higher health care expenditures and lost productivity, compared to adults without a history of cancer. Using Medical Expenditure Panel Survey data, we present nationally representative estimates of the economic burden among people who were diagnosed with cancer in adolescence or young adulthood. Our findings demonstrate that surviving cancer at this age is associated with a substantial economic burden. Compared to adults without a history of cancer, adolescent and young adult cancer survivors had excess annual medical expenditures of $3,170 per person and excess annual productivity losses of $2,250 per person. Multifaceted prevention strategies, including education and sustained intervention programs to ensure access to lifelong risk-based follow-up care, may be effective ways to improve the economic outcomes associated with cancer survivorship in this population.
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Physical symptoms and emotional distress contribute to significant social, economic, and health burdens for young adult cancer survivors.
“Consequently, physical symptoms and emotional distress contribute to significant social, economic, and health burdens for YA at a time when they should otherwise be on an upward social, economic, and health trajectory [18–22].”
From Improving symptom management for survivors of young adult cancer: rationale and study protocol for a pilot randomized controlled trial (2024) · cites this paper as [18]
The Discussion reports substantial health and economic burdens among adolescent and young adult cancer survivors, including physical limitations, reduced employment, and lost productivity. The paper also mentions psychosocial challenges, but it does not establish that emotional distress contributes to those burdens or separately assess the effects of physical symptoms and emotional distress. (LLM, conf=0.84)
Experimental — accuracy not yet measuredThese challenges may lead to underemployment, excessive medical expenditures, and productivity losses.
“These challenges may translate into underemployment, excessive medical expenditures, and significant corresponding productivity losses.9”
From Promoting resilience in adolescents and young adults with cancer: Results from the PRISM randomized controlled trial (2018) · cites this paper as [9]
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“Consequently, physical symptoms and emotional distress contribute to significant social, economic, and health burdens for YA at a time when they should otherwise be on an upward social, economic, and health trajectory [18–22].”
Background
- Authors
- Guy, G. P., Yabroff, K. R., Ekwueme, D. U., Smith, A. W., Dowling, E. C., Rechis, R., Nutt, S., & Richardson, L. C.
- Affiliations
- Centers for Disease Control and Prevention (US)
- National Cancer Institute (US)
- Donatus U. Ekwueme is a senior health economist in the Division of Cancer Prevention and Control, CDC.
- Ashley Wilder Smith is a behavioral scientist in the Division of Cancer Control and Population Sciences, NCI.
- Massachusetts General Hospital (US)
- Livestrong Foundation (US)
- ORCID
- Venue
- Health Affairs
- Publisher
- Health Affairs Publishing, LLC
- Published
- 2014-06
- Volume
- 33
- Issue
- 6
- Pages
- 1024-1031
- ISSN
- 0278-2715 (ISSN-L)
- 1544-5208
- PMC
- PMC4582764
- OpenAlex
- W2033563009
- Cited by
- 201
- References
- 26
- Citations by year
- 2026: 13 · 2025: 11 · 2024: 13 · 2023: 20 · 2022: 23 · 2021: 26 · 2020: 23 · 2019: 19 · 2018: 14 · 2017: 13 · 2016: 16 · 2015: 7 · 2014: 3
- FWCI
- 32.23
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Health Affairs (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (CC999999)
- Topics
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Economic and Financial Impacts of Cancer
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
- Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
- Keywords
- adolescent and young adult cancer, cancer survivors, economic burden of cancer, health care expenditure, productivity loss, health care costs, cancer survivorship, cancer prevention
- MeSH terms
- Adolescent, Adult, Age Factors, Disability Evaluation, Health Expenditures, Female, Health Services Accessibility, Humans, Long-Term Care, Male, Neoplasms, United States, Health Care Costs, Cost of Illness, Survivors, Sick Leave, Young Adult
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