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Zinc Nutritional Status in Obese Children and Adolescents
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Studies in animals and humans have corroborated that zinc (Zn) metabolism is altered in obesity. The present work intends to evaluate the Zn nutritional status in obese children and adolescents by the determination of some biochemical parameters and analyses of the diets. The investigation was carried out in a group of obese children and adolescents (n = 23) and compared to a control group (n = 21), both between 7 and 14 yr of age. A software analyzed diet information from 3-d food records. Body composition was evaluated by body mass index, bioelectrical impedance, and skinfold measurements. Zinc nutritional status was evaluated by Zn determination in plasma, erythrocyte, and 24-h urine, by atomic absorption spectrophotometry (lambda = 213.9 nm). Diets consumed by both groups had marginal concentrations of zinc. Zinc concentrations in plasma and erythrocytes were significantly lower in the obese group. Urinary zinc excretion was significantly higher in the same group. The results allowed one to conclude that zinc nutritional status in obese individuals is altered.
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A trial conducted in elderly patients with MDD showed that a single 300-kIU dose of vitamin D results in a decreased score of depression.
“a trial conducted in elderly patients with MDD showed that a single 300-kIU dose of vitamin D results in a decreased score of depression (57);”
From Effects of zinc, vitamin D, and their co-supplementation on mood, serum cortisol, and brain-derived neurotrophic factor in patients with obesity and mild to moderate depressive symptoms: A phase II, 12-wk, 2 × 2 factorial design, double-blind, randomized, placebo-controlled trial (2020) · cites this paper as [57]
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Khajeh, M., Hassanizadeh, S., Tabrizi, F. P. F., Hassanizadeh, R., Vajdi, M., & Askari, G. (2024) · Biological Trace Element Research · doi:10.1007/s12011-024-04059-x · Cited by 11
“Several studies have shown that obese people have lower zinc levels [16, 17].”
Dietary Inflammatory Potential in Pediatric Diseases: A Narrative Review
Tosi, M., Montanari, C., Bona, F., Tricella, C., Agostinelli, M., Dolor, J., Chillemi, C., Profio, E. D., Tagi, V. M., Vizzuso, S., et al. (2023) · Nutrients · doi:10.3390/nu15245095 · Cited by 16
“…should focus more on the specific nutritional changes required to enable , both in terms of dietary patterns and specific nutrients’ intake, and how influence the risk of occurrence of other diseases or the composition of the both children and ,48,50,57,58,64,65] that influences inflammatory pathways.”
BackgroundDoble carga de malnutrición durante el crecimiento: ¿una realidad latente en colombia?
Giraldo, G. A. C., Castaño‐Moreno, E., & Charry, D. G. (2016) · Revista de Salud Pública · doi:10.15446/rsap.v18n4.47769 · Cited by 10
Is Zinc Concentration in Toxic Phase Plasma Related to Dengue Severity and Level of Transaminases?
Laoprasopwattana, K., Tangcheewawatthanakul, C., Tunyapanit, W., & Sangthong, R. (2013) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0002287 · Cited by 9
“Other studies have found that obese or malnourished children with DVI had higher morbidity and mortality rates than those with normal body weight, suggesting that nutritional status might play an important role in the immunopathogenesis of DVI [3,4], and also that obese and malnourished children had higher proportions…”
BackgroundTubek, S. (2006) · Biological Trace Element Research · doi:10.1385/bter:114:1:55 · Cited by 9
Veghari, G., & Mohsen, S. (2007) · Journal of Applied Sciences · doi:10.3923/jas.2007.2681.2685 · Cited by 8
Tubek, S. (2006) · Biological Trace Element Research · doi:10.1385/bter:114:1:135 · Cited by 8
Grabeklis, A. R., Skalny, A. V., Ajsuvakova, O. P., Skalnaya, A. A., Mazaletskaya, A. L., Клочкова, С. В., Chang, S. J. S., Nikityuk, D. B., Геннадиевна, С. М., & Tinkov, A. A. (2019) · Biological Trace Element Research · doi:10.1007/s12011-019-01938-6 · Cited by 8
Obesity and Micronutrient Deficiencies
Tussing-Humphreys, L. M., & Nguyen, V. T. (2014) · Humana Press eBooks · doi:10.1007/978-1-62703-770-9_10 · Cited by 7
Rathnayake, K. M., Silva, K., & Jayawardena, R. (2016) · Trials · doi:10.1186/s13063-016-1651-3 · Cited by 6
“A low plasma zinc level is associated with obesity [7, 8].”
BackgroundMartínez-Navarro, I., Vilchis‐Gil, J., Cossío-Torres, P. E., Hernández‐Mendoza, H., Klünder‐Klünder, M., Layseca‐Espinosa, E., Galicia-Cruz, O. G., & Ríos-Lugo, M. J. (2022) · Biological Trace Element Research · doi:10.1007/s12011-022-03533-8 · Cited by 6
Antioxidant Supplementation in Childhood Obesity: A Path to Improved Metabolic Health?
Lupu, A., Mihai, C. M., Dragan, F., Tarnita, I., Alecsa, M., Chisnoiu, T., Morariu, I. D., Cuciureanu, M. D., Nedelcu, A. H., Șalaru, D. L., et al. (2025) · Antioxidants · doi:10.3390/antiox14040466 · Cited by 5
“Given that zinc plays a crucial role in the synthesis and secretion of insulin, the findings suggest a need for further investigation into the potential involvement of zinc in IR, a common feature of obesity [159].”
Different trends of Cr, Fe and Zn contents in hair between obese, overweight and normal-weight men
Lokvencová, L., Zvěřina, O., & Kuta, J. (2021) · Central European Journal of Public Health · doi:10.21101/cejph.a6912 · Cited by 4
Marques, A. G., Sarni, R. O. S., Lopes, L. A., Lopes, E., & Amâncio, O. M. S. (2016) · Nutrire · doi:10.1186/s41110-016-0010-1 · Cited by 4
Chim, S. M., Howell, K., Dronzek, J., Wu, W., Hout, C. V. V., Ferreira, M. A. R., Ye, B., Li, A. H., Brydges, S. D., Vinayagam, A., et al. (2024) · eLife · doi:10.7554/elife.90419.2 · Cited by 3
Omar, O., Abdelgawad, M., Elwafa, R. A., & Mohamed, E. (2017) · Egyptian Journal of Obesity Diabetes and Endocrinology · doi:10.4103/ejode.ejode_6_17 · Cited by 3
Association between serum zinc level and lipid profiles in children with spinal muscular atrophy
Long, Q., Feng, Y., Chen, F., Wang, W., Ma, M., & Mao, S. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.960006 · Cited by 3
“Indeed, many studies have confirmed the lower levels of serum zinc in individuals who are overweight and who have obesity and diabetes (20, 21, 31).”
BackgroundContent of bioelements in the lungs and liver in rats with alimentary obesity
Trunova, V. A., Сидорина, А. В., Zvereva, V. V., Чурин, Б. В., Старкова, Е. В., & Сороколетов, Д. С. (2015) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2015.08.005 · Cited by 3
Emerging Nanonutraceuticals against Obesity
Ni, L., Peng, M., Liang, Y., Ye, X., Zheng, H., Guo, D., Yang, L., Li, X., & Chen, R. (2025) · Small Science · doi:10.1002/smsc.202500116 · Cited by 3
Severe Dietary Zinc Deficiency Does Not Significantly Alter Energy Balance in Adult Mice
Murdoch, C. C., Weiss, A., Enriquez, K. T., Traina, K. A., Drury, S. L., Winn, N. C., Lantier, L., & Skaar, E. P. (2025) · Journal of Nutrition and Metabolism · doi:10.1155/jnme/6911386 · Cited by 2
“As such, Zn supplementation has been found to mitigate symptoms of metabolic disease as well as malnutrition in humans, representing a promising dietary intervention to circumvent pathology derived from Zn defciency [11, 14, 15].”
Qui manque d’antioxydants, et comment le savoir ?
Roussel, A. (2009) · Cahiers de Nutrition et de Diététique · doi:10.1016/j.cnd.2009.05.001 · Cited by 2
Pathophysiological disorders in iron metabolism in the development of obesity and metabolic syndrome
Smirnova, O. V., Moskalenko, O. L., Каспаров, Э. В., & Каспарова, И. Э. (2022) · Meditsinskiy sovet = Medical Council · doi:10.21518/2079-701x-2022-16-6-264-272 · Cited by 2
Chim, S. M., Howell, K., Dronzek, J., Wu, W., Hout, C. V. V., Ferreira, M. A. R., Ye, B., Li, A. H., Brydges, S. D., Arunachalam, V., et al. (2023) · eLife · doi:10.7554/elife.90419 · Cited by 2
Чурин, Б. В., Trunova, V. A., Сидорина, А. В., Zvereva, V. V., & Astashov, V. V. (2013) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-013-2309-8 · Cited by 1
Payahoo, L., Mobasseri, M., Bishak, Y. K., Jafarabadi, M. A., & Ostadrahimi, A. (2013) · Alborz University Medical Journal · doi:10.18869/acadpub.aums.2.1.7 · Cited by 1
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Чурин, Б. В., Trunova, V. A., Сидорина, А. В., Zvereva, V. V., & Astashov, V. V. (2015) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-015-2777-0
EFEITO DA SUPLEMENTAÇÃO DE ZINCO EM INDIVÍDUOS OBESOS SUBMETIDOS À CIRURGIA BARIÁTRICA
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Estado nutricional e desempenho motor de escolares
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Chim, S. M., Howell, K., Dronzek, J., Wu, W., Hout, C. V. V., Ferreira, M. A. R., Ye, B., Li, A. H., Brydges, S. D., Arunachalam, V., et al. (2023) · eLife · doi:10.7554/elife.90419.1
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Питание матери и детей раннего возраста с точки зрения метаболического программирования
Makarova, N. P., Ladodo, O. B., Butskaya, T. V., Fisenko, А. P., Андреевна, С. С., Chemakina, D. S., Yasakov, D. S., & Анатольевна, Н. Е. (2022) · Medical Opponent · doi:10.64831/2619-0001.2022.2.183545
Metadata
- Authors
- Cozzolino, S. M. F., Marreiro, D. D. N., & Fisberg, M.
- Affiliations
- Universidade de São Paulo (BR)
- Universidade São Marcos (BR)
- Venue
- Biological Trace Element Research
- Published
- 2002
- Volume
- 86
- Issue
- 2
- Pages
- 107-122
- ISSN
- 0163-4984 (ISSN-L)
- OpenAlex
- W1965743075
- Cited by
- 96
- References
- 37
- Citations by year
- 2025: 3 · 2024: 4 · 2023: 7 · 2022: 8 · 2021: 3 · 2020: 6 · 2019: 6 · 2018: 1 · 2017: 4 · 2016: 5 · 2015: 5 · 2014: 6 · 2013: 9 · 2012: 5
- FWCI
- 1.16
- Type
- journal article
- Language
- en
- Open access
- Licence
- other-oa
- Locations
- Biological Trace Element Research (publishedVersion)
- PubMed (publishedVersion)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- Americanae (AECID Library) (submittedVersion, other-oa)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Heavy Metal Exposure and Toxicity
- Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
- Keywords
- zinc status, childhood obesity, adolescent obesity, plasma zinc, erythrocyte zinc, urinary zinc excretion, zinc metabolism, zinc intake, body composition
- MeSH terms
- Adolescent, Child, Child Nutritional Physiological Phenomena, Diet, Erythrocytes, Female, Humans, Male, Obesity, Reference Values, Skinfold Thickness, Zinc, Nutrition Assessment, Body Mass Index, Case-Control Studies
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