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Evaluation of Antimitotic Agents by Quantitative Comparisons of Their Effects on the Polymerization of Purified Tubulin
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Cites
Promotion of microtubule assembly in vitro by taxol
SCHIFF, P. B., FANT, J., & HORWITZ, S. B. (1979) · Nature · doi:10.1038/277665a0 · Cited by 3,600
Microtubule Assembly in the Absence of Added Nucleotides
Shelanski, M. L., Gaskin, F., & Cantor, C. R. (1973) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.70.3.765 · Cited by 2,053
Microtubule Formation in vitro in Solutions Containing Low Calcium Concentrations
Weisenberg, R. C. (1972) · Science · doi:10.1126/science.177.4054.1104 · Cited by 1,210
Turbidimetric studies of the in vitro assembly and disassembly of porcine neurotubules
Gaskin, F., Cantor, C. R., & Shelanski, M. L. (1974) · Journal of Molecular Biology · doi:10.1016/0022-2836(74)90048-5 · Cited by 816
Mechanism of Action of Antitumor Drugs that Interact with Microtubules and Tubulin
Jordan, M. (2012) · Current Medicinal Chemistry-Anti-Cancer Agents · doi:10.2174/1568011023354290 · Cited by 775
Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly
Cleveland, D. W., Hwo, S.-Y., & Kirschner, M. W. (1977) · Journal of Molecular Biology · doi:10.1016/0022-2836(77)90214-5 · Cited by 730
D'Amato, R. J., Lin, C. M., Flynn, E., Folkman, J., & Hamel, E. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.9.3964 · Cited by 406
Self-citationWilson, L. (1970) · Biochemistry · doi:10.1021/bi00827a026 · Cited by 386
Discodermolide, A Cytotoxic Marine Agent That Stabilizes Microtubules More Potently Than Taxol,
ter Haar, E., Kowalski, R. J., Hamel, E., Lin, C. M., Longley, R. E., Gunasekera, S. P., Rosenkranz, H. S., & Day, B. W. (1996) · Biochemistry · doi:10.1021/bi9515127 · Cited by 382
Self-citationBai, R. L., Paull, K. D., Herald, C. L., Malspeis, L., Pettit, G. R., & Hamel, E. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)98491-7 · Cited by 379
Self-citationThe benzimidazole anthelmintic agents‐a review
McKELLAR, Q. A., & SCOTT, E. W. (1990) · Journal of Veterinary Pharmacology and Therapeutics · doi:10.1111/j.1365-2885.1990.tb00773.x · Cited by 371
Interaction of oncodazole (R 17934), a new anti-tumoral drug, with rat brain tubulin
Hoebeke, J., Van Nijen, G., & De Brabander, M. (1976) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(76)90524-6 · Cited by 368
Ben-Chetrit, E., & Levy, M. (1998) · Seminars in Arthritis and Rheumatism · doi:10.1016/s0049-0172(98)80028-0 · Cited by 354
Laulimalide and isolaulimalide, new paclitaxel-like microtubule-stabilizing agents.
Mooberry, S. L., Tien, G., Hernandez, A. H., Plubrukarn, A., & Davidson, B. S. (1999) · PubMed · Cited by 330
Ionic and nucleotide requirements for microtubule polymerization in vitro
Olmsted, J. B., & Borisy, G. G. (1975) · Biochemistry · doi:10.1021/bi00684a032 · Cited by 293
Bai, R. L., Pettit, G. R., & Hamel, E. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)44880-0 · Cited by 286
Self-citationInteractions of colchicine with tubulin
Hastie, S. B. (1991) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(91)90067-v · Cited by 286
Lin, C. M., Singh, S. B., Chu, P. S., Dempcy, R. O., Schmidt, J. M., Pettit, G. R., & Hamel, E. (1988) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)09364-2 · Cited by 278
Self-citationPryor, D. E., O'Brate, A., Bilcer, G., Díaz, J. F., Wang, Y., Wang, Y., Kabaki, M., Jung, M. K., Andreu, J. M., Ghosh, A. K., et al. (2002) · Biochemistry · doi:10.1021/bi020211b · Cited by 256
Self-citationLattice defects in microtubules: protofilament numbers vary within individual microtubules
Chrétien, D., Metoz, F., Verde, F., Karsenti, E., & Wade, R. (1992) · The Journal of cell biology · doi:10.1083/jcb.117.5.1031 · Cited by 248
Role of tubulin-associated proteins in microtubule nucleation and elongation
Murphy, D. B., Johnson, K. A., & Borisy, G. G. (1977) · Journal of Molecular Biology · doi:10.1016/0022-2836(77)90021-3 · Cited by 228
Hamel, E., & Lin, C. M. (1984) · Biochemistry · doi:10.1021/bi00313a026 · Cited by 226
Self-citationLong, B. H., Carboni, J. M., Wasserman, A. J., CORNELL, L., Casazza, A. M., Jensen, P. R., Lindel, T., Fenical, W., & Fairchild, C. R. (1998) · PubMed · Cited by 218
Dimethyl sulfoxide-induced self-assembly of tubulin lacking associated proteins.
Himes, R. H., Burton, P. R., & Gaito, J. M. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)40053-6 · Cited by 208
Interaction of anthelmintic benzimidazoles and benzimidazole derivatives with bovine brain tubulin
Friedman, P. A., & Platzer, E. G. (1978) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(78)90334-3 · Cited by 202
Hamel, E., & Lin, C. M. (1981) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(81)90253-8 · Cited by 180
Self-citationMagnesium-induced self-association of calf brain tubulin. I. Stoichiometry
Frigon, R. P., & Timasheff, S. N. (1975) · Biochemistry · doi:10.1021/bi00692a001 · Cited by 173
Paull, K. D., Lin, C. M., Malspeis, L., & Hamel, E. (1992) · PubMed · Cited by 171
Self-citationShan, B., Medina, J. C., Santha, E., Frankmoelle, W. P., Chou, T.-C., Learned, R. M., Narbut, M. R., Stott, D., Wu, P., Jaen, J. C., et al. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.10.5686 · Cited by 164
Hamel, E., Sackett, D. L., Vourloumis, D., & Nicolaou, K. C. (1999) · Biochemistry · doi:10.1021/bi983023n · Cited by 159
Self-citationColchicine inhibition of microtubule assembly via copolymer formation.
Sternlicht, H., & Ringel, I. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)86741-8 · Cited by 146
Structure−Activity Requirements for Flavone Cytotoxicity and Binding to Tubulin
Beutler, J. A., Hamel, E., Vlietinck, A. J., et al. (1998) · Journal of Medicinal Chemistry · doi:10.1021/jm970842h · Cited by 145
Self-citationAlterations in number of protofilaments in microtubules assembled in vitro.
Pierson, G. B., Burton, P. R., & Himes, R. H. (1978) · The Journal of Cell Biology · doi:10.1083/jcb.76.1.223 · Cited by 140
Mg2+ dependence of guanine nucleotide binding to tubulin.
Correia, J. J., Baty, L. T., & Williams, R. C. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)45374-4 · Cited by 131
Bai, R., Cichacz, Z. A., Herald, C. L., et al. (1993) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)13253-7 · Cited by 129
Zinc ion-induced assembly of tubulin.
Gaskin, F., & Kress, Y. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)39936-2 · Cited by 126
Bai, R., Taylor, G. F., Cichacz, Z. A., Herald, C. L., Kepler, J. A., Pettit, G. R., & Hamel, E. (1995) · Biochemistry · doi:10.1021/bi00030a009 · Cited by 121
Self-citationA new anti-tubulin agent containing the benzo[b]thiophene ring system
Pinney, K. G., Bounds, A. D., Dingeman, K. M., Mocharla, V. P., Pettit, G. R., Bai, R., & Hamel, E. (1999) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(99)00143-2 · Cited by 119
Self-citationLataste, H., Sénilh, V., Wright, M., Guénard, D., & Potìer, P. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.13.4090 · Cited by 117
Interaction of vinblastine with steady-state microtubules in vitro
Wilson, L., Jordan, M. A., Morse, A. N. C., & Margolis, R. L. (1982) · Journal of Molecular Biology · doi:10.1016/0022-2836(82)90035-3 · Cited by 113
Identification of a distinct class of vinblastine binding sites on microtubules
Jordan, M. A., Margolis, R. L., Himes, R. H., & Wilson, L. (1986) · Journal of Molecular Biology · doi:10.1016/0022-2836(86)90406-7 · Cited by 106
Mapping the Binding Site of Colchicinoids on β-Tubulin
Bai, R., Covell, D. G., Pei, X., Ewell, J. B., Nguyen, N. Y., Brossi, A. R., & Hamel, E. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m005299200 · Cited by 97
Self-citationBlokhin, A. V., Yoo, H., Geralds, R. S., Nagle, D. G., Gerwick, W. H., & Hamel, E. (1995) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)10502-6 · Cited by 86
Self-citationAntimitotic Peptides and Depsipeptides
Hamel, E., & Covell, D. G. (2005) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/1568011023354263 · Cited by 70
Self-citationTubulin-zinc interactions: binding and polymerizaton studies
Eagle, G. R., Zombola, R. R., & Himes, R. H. (1983) · Biochemistry · doi:10.1021/bi00270a032 · Cited by 67
Legault, J., Gaulin, J.-F., Mounetou, E., BOLDUC, S., Lacroix, J., Poyet, P., & Gaudreault, R. C. (2000) · PubMed · Cited by 60
Stabilization of the colchicine-binding activity of tubulin by organic acids
Hamel, E., & LIN, C. (1981) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(81)90231-2 · Cited by 59
Self-citationA Steroid Derivative with Paclitaxel-Like Effects on Tubulin Polymerization
Verdier‐Pinard, P., Wang, Z., Mohanakrishnan, A. K., Cushman, M., & Hamel, E. (2000) · Molecular Pharmacology · doi:10.1016/s0026-895x(24)26423-3 · Cited by 58
Self-citationManganous ion binding to tubulin.
Buttlaire, D. H., Czuba, B. A., Stevens, T. H., Lee, Y. C., & Himes, R. H. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)86008-8 · Cited by 52
The importance of the phenyl‐tropolone ‘ aS ’ configuration in colchicine's binding to tubulin
Yeh, H. J. C., Chrzanowska, M., & Brossi, A. R. (1988) · FEBS Letters · doi:10.1016/0014-5793(88)80802-0 · Cited by 49
The magnesium–GTP interaction in microtubule assembly
Grover, S. K., & Hamel, E. (1994) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1994.tb18854.x · Cited by 46
Self-citationRPR112378 and RPR115781: Two Representatives of a New Family of Microtubule Assembly Inhibitors
Combeau, C., Provost, J., Lancelin, F., Tournoux, Y., Prod'homme, F., Herman, F., Lavelle, F., Leboul, J., & Vuilhorgne, M. (2000) · Molecular Pharmacology · doi:10.1016/s0026-895x(24)26421-x · Cited by 45
Böhm, K. J., Vater, W., Fenske, H., & Unger, E. (1984) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(84)90049-7 · Cited by 39
Induction of Polymerization of Purified Tubulin by Sulfonate Buffers
Waxman, P. G., del Campo, A. A., Lowe, M., et al. (1981) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1981.tb05679.x · Cited by 37
Hamel, E., Lustbader, J., & Lin, C. M. (1984) · Biochemistry · doi:10.1021/bi00317a033 · Cited by 37
Self-citationSteganacin: An inhibitor of HeLa cell growth and microtubule assembly
Schiff, P. B., Kende, A. S., & Horwitz, S. B. (1978) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(78)91223-8 · Cited by 36
Sternlicht, H., Ringel, I., & Szasz, J. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)70538-9 · Cited by 28
Hamel, E., Blokhin, A. V., Nagle, D. G., Yoo, H., & Gerwick, W. H. (1995) · Drug Development Research · doi:10.1002/ddr.430340204 · Cited by 22
Self-citation2,4-Dichlorobenzyl thiocyanate, an antimitotic agent that alters microtubule morphology.
Abraham, I., Dion, R. L., Chi, D. M., Gottesman, M. M., & Hamel, E. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.18.6839 · Cited by 18
Self-citationThe relationship between cobalt binding to tubulin and the stimulation of assembly.
Himes, R. H., Lee, Y. C., Eagle, G. R., HASKINS, K. M., Bäbler, S., & Ellermeier, J. R. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)83855-3 · Cited by 17
Metadata
- Authors
- Hamel, E.
- Venue
- Cell Biochemistry and Biophysics
- Published
- 2003
- Volume
- 38
- Issue
- 1
- Pages
- 1-22
- ISSN
- 1085-9195 (ISSN-L)
- OpenAlex
- W1969615301
- Cited by
- 272
- References
- 60
- FWCI
- 2.90
- Type
- journal article
- Language
- en
- Open access
- closed
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