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The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

The crucial roles of inflammatory mediators in inflammation: A review

Open access
Abdulkhaleq, L. A., Assi, M. A., Abdullah, Rasedee, Zamri-Saad, M., Taufiq-Yap, Y. H., Hezmee, M. N. M.·2018·Veterinary World

Abstract

The inflammatory response is a crucial aspect of the tissues' responses to deleterious inflammogens. This complex response involves leukocytes cells such as macrophages, neutrophils, and lymphocytes, also known as inflammatory cells. In response to the inflammatory process, these cells release specialized substances which include vasoactive amines and peptides, eicosanoids, proinflammatory cytokines, and acute-phase proteins, which mediate the inflammatory process by preventing further tissue damage and ultimately resulting in healing and restoration of tissue function. This review discusses the role of the inflammatory cells as well as their by-products in the mediation of inflammatory process. A brief insight into the role of natural anti-inflammatory agents is also discussed. The significance of this study is to explore further and understand the potential mechanism of inflammatory processes to take full advantage of vast and advanced anti-inflammatory therapies. This review aimed to reemphasize the importance on the knowledge of inflammatory processes with the addition of newest and current issues pertaining to this phenomenon.

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Crossref · 10.14202/vetworld.2018.627-635

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Metadata

Authors
Abdulkhaleq, L. A., Assi, M. A., Abdullah, R., Zamri-Saad, M., Taufiq-Yap, Y. H., & Hezmee, M. N. M.
Venue
Veterinary World
Published
2018-05
Volume
11
Issue
5
Pages
627-635
ISSN
  • 0972-8988 (ISSN-L)
  • 2231-0916
OpenAlex
W2804508211
Cited by
775
References
18
FWCI
17.79
Type
journal article
Language
en
Open access
gold

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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