Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update

Cited by (744)

Items 201–300 of 744

1. Biodegradation of acetaminophen: Current knowledge and future directions with mechanistic insights from omics
   Bhavana Pandey, Anand Kumar Pandey, Laliteshwari Bhardwaj, Suresh Kumar Dubey · 2025 · Chemosphere
2. Early Detection of Acute Drug-Induced Liver Injury in Mice by Noninvasive Near-Infrared Fluorescence Imaging
   Kristine O. Vasquez, Jeffrey D. Peterson · 2017 · Journal of Pharmacology and Experimental Therapeutics
3. Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose
   Sarah Piel, Imen Chamkha, Adam Kozak Dehlin, Johannes K. Ehinger, Fredrik Sjövall, Eskil Elmér, Magnus Joakim Hansson · 2020 · PLoS ONE
4. Aryl Hydrocarbon Receptor Activity in Hepatocytes Sensitizes to Hyperacute Acetaminophen-Induced Hepatotoxicity in Mice
   Fenja Amrei Schuran, Christoph Lommetz, Andreas Steudter, Ahmed Ghallab, Björn Wieschendorf, Dorothee Schwinge, Sebastian Zuehlke, Jörg Reinders, Jöerg Heeren, Ansgar Wilhelm Lohse et al. · 2020 · Cellular and Molecular Gastroenterology and Hepatology
5. Drug-Induced Liver Injury in the Setting of Analgesic Use
   Umar Darr, Norman Sussman · 2019 · Clinics in Liver Disease
6. Fabrication of polypyrrole/Au nanoflowers modified gold electrode for highly sensitive sensing of paracetamol in pharmaceutical formulation
   Waleed Ahmed El-Said, Osama Nasr, Ahmed I. A. Soliman, Emad A. Elshehy, Ziya Ahmad Khan, Fatma K. Abdel‐Wadood · 2021 · Applied Surface Science Advances
7. The protective effect of carvacrol on acetaminophen-induced renal damage in male rats
   Alireza Najafizadeh, Ayat Kaeidi, Mohammad Reza Rahmani, Elham Hakimizadeh, Jalal Hassanshahi · 2022 · Molecular Biology Reports
8. Novel luteolin@pro-phytomicelles: In vitro characterization and in vivo evaluation of protection against drug-induced hepatotoxicity
   Kaichao Song, Liping Zhou, Cuicui Wang, Zhi‐Xin Yuan, Qilong Cao, Xianggen Wu, Mengshuang Li · 2022 · Chemico-Biological Interactions
9. Multiple Facets of Cellular Homeostasis and Regeneration of the Mammalian Liver
   Stacey S. Huppert, Robert E. Schwartz · 2022 · Annual Review of Physiology
10. Taming Food–Drug Interaction Risk: Potential Inhibitory Effects of Citrus Juices on Cytochrome Liver Enzymes Can Safeguard the Liver from Overdose Paracetamol-Induced Hepatotoxicity
    Aya S. Shalaby, Hanaa H. Eid, Riham A. El‐Shiekh, Osama G. Mohamed, Ashootosh Tripathi, Ahmed Ali Al-Karmalawy, Amany Ameen Sleem, Fatma A. Morsy, Khaled M. Ibrahim, Soad Hanna Tadros et al. · 2023 · ACS Omega
11. Hepatoprotective Effects of Zerumbone against Paracetamol-Induced Acute Hepatotoxicity in Rats
    Asmah Hamid, Liow Say Lee, Saiful Ridzuan Karim, Nurul Farhana Jufri · 2018 · Malaysian Journal of Medical Sciences
12. Fibroblast growth factors 19 and 21 in acute liver damage
    Zhao Shan, Gloria Álvarez‐Sola, Iker Uriarte, María Arechederra, Maite G. Fernández‐Barrena, Carmen Berasain, Cynthia Ju, Matias Antonio Avila · 2018 · Annals of Translational Medicine
13. (E)-2-Cyano-3-(1H-Indol-3-yl)-N-Phenylacrylamide, a Hybrid Compound Derived from Indomethacin and Paracetamol: Design, Synthesis and Evaluation of the Anti-Inflammatory Potential
    Pablo Rayff da Silva, Maria de Almeida, Jamire Muriel da Silva, Sonaly Lima Albino, Renan Fernandes do Espírito Santo, Maria do Carmo Alves de Lima, Cristiane Flora Villarreal, Ricardo Olímpio de Moura, Vanda Lúcia dos Santos · 2020 · International Journal of Molecular Sciences
14. Excessive Plasmin Compromises Hepatic Sinusoidal Vascular Integrity After Acetaminophen Overdose
    Siqi Gao, Robert Silasi‐Mansat, Amanda R. Behar, Florea Lupu, Courtney T. Griffin · 2018 · Hepatology
15. Inhibition of lipolysis: A novel explanation for the hypothermic actions of acetaminophen in non-febrile rodents
    Bashir, Shazma, Elegunde, Busayo, Morgan, Winston A. · 2020 · Biochemical Pharmacology
16. Acetaminophen, a therapeutic or an extremely toxic remedy – a review
    Genica Caragea, Oana Avram, Andreea Marilena Păuna, Andreea Cristina Costea, Miruna Tudosie · 2022 · Journal of Mind and Medical Sciences
17. Acetaminophen for the patent ductus arteriosus: has safety been adequately demonstrated?
    Clyde J. Wright, David J. McCulley, Souvik Mitra, Erik A. Jensen · 2023 · Journal of Perinatology
18. A systems approach reveals species differences in hepatic stress response capacity
    Giusy Russomanno, Rowena L. C. Sison-Young, Lucia A Livoti, Hannah Coghlan, Rosalind E. Jenkins, Steven J. Kunnen, Ciarán Fisher, Dennis Reddyhoff, Iain B. Gardner, Adeeb H. Rehman et al. · 2023 · Toxicological Sciences
19. Intensive Care Management of Acute Liver Failure: Considerations While Awaiting Liver Transplantation
    Anil B. Seetharam · 2019 · Journal of Clinical and Translational Hepatology
20. Tetrahydroxy stilbene glycoside attenuates acetaminophen‐induced hepatotoxicity by UHPLC‐Q‐TOF/MS‐based metabolomics and multivariate data analysis
    Yan Gao, Juntong Li, Xiang Li, Xun Li, Songwei Yang, Nai‐Hong Chen, Lin Li, Lan Zhang · 2020 · Journal of Cellular Physiology
21. Transdermal buprenorphine for moderate chronic noncancer pain syndromes
    Joseph V. Pergolizzi, Flaminia Coluzzi, Robert Taylor · 2018 · Expert Review of Neurotherapeutics
22. Prolonged neutrophil survival at necrotic sites is a fundamental feature for tissue recovery and resolution of hepatic inflammation
    Matheus Silvério Mattos, Mateus Eustáquio Lopes, Alan de Araujo, Débora Moreira Alvarenga, Brenda Naemi Nakagaki, Kassiana Mafra, Camila Dutra Moreira de Miranda, Ariane Barros Diniz, Maísa Mota Antunes, Maria Alice Freitas Lopes et al. · 2020 · Journal of Leukocyte Biology
23. Chemogenetic Approaches to Probe Redox Pathways: Implications for Cardiovascular Pharmacology and Toxicology
    Benjamin S. Steinhorn, Emrah Eroğlu, Thomas M. Michel · 2021 · The Annual Review of Pharmacology and Toxicology
24. Kahweol Protects against Acetaminophen‐Induced Hepatotoxicity in Mice through Inhibiting Oxidative Stress, Hepatocyte Death, and Inflammation
    Jung‐Yeon Kim, Jaechan Leem, Gyun Moo Kim · 2022 · BioMed Research International
25. Adipose-Derived Mesenchymal Stem Cells Inhibit JNK-Mediated Mitochondrial Retrograde Pathway to Alleviate Acetaminophen-Induced Liver Injury
    Yelei Cen, Guohua Lou, Jinjin Qi, Minwei Li, Min Zheng, Yanning Liu · 2023 · Antioxidants
26. Identification of distinct immune infiltration and potential biomarkers in patients with liver ischemia-reperfusion injury
    Zhangliu Jin, Meng Dou, Weihui Peng, Boen Xiao, Jinjin Liu, Wen Meng, Wei Liu · 2023 · Life Sciences
27. Protective Effect of Water-Soluble Acacetin Prodrug on APAP-Induced Acute Liver Injury Is Associated with Upregulation of PPARγ and Alleviation of ER Stress
    Jiaen Miao, Shujun Yao, Hao Xuan Sun, Zhe Jiang, Zhe Gao, Jia Feng Xu, Kuihao Chen · 2023 · International Journal of Molecular Sciences
28. Glutaredoxin-1 alleviates acetaminophen-induced liver injury by decreasing its toxic metabolites
    Ying Xin Xu, Yan Xia, Qinhui Liu, Xiandan Jing, Qin Tang, Jinhang Zhang, Qingyi Jia, Zijing Zhang, Jiahui Li, Jia-Hao Chen et al. · 2023 · Journal of Pharmaceutical Analysis
29. Enhancing the potency of in vivo lentiviral vector mediated gene therapy to hepatocytes
    Cesare Canepari, Michela Milani, Chiara Simoni, Francesco Starinieri, Monica Volpin, Anna Fabiano, Mauro Biffi, Fabio Russo, Rossana Norata, Martina Rocchi et al. · 2025 · Nature Communications
30. Application of the comparison approach to open TG-GATEs: A useful toxicogenomics tool for detecting modes of action in chemical risk assessment
    Harm J. Heusinkveld, Paul F. K. Wackers, Willem G.E.J. Schoonen, Leo van der Ven, Jeroen L. A. Pennings, Mirjam Luijten · 2018 · Food and Chemical Toxicology
31. Determination of five nucleosides by LC‐MS/MS and the application of the method to quantify N6‐methyladenosine level in liver messenger ribonucleic acid of an acetaminophen‐induced hepatotoxicity mouse model
    Ruijuan Liu, Fang Zhao, Jingyao Wei, Pei Yu, Ji Zhang, Yueqin Wang, Zeyun Li, Jiali Zhang, Xiaojian Zhang, Xin Tian · 2019 · Journal of Separation Science
32. Hepatoprotective effect of essential oils of Nepeta cataria L. on acetaminophen-induced liver dysfunction
    Juan Tan, Jing Li, Jilei Ma, Feng Qiao · 2019 · Bioscience Reports
33. Pain and Inflammation Management in Older Adults: A Brazilian Consensus of Potentially Inappropriate Medication and Their Alternative Therapies
    Fabiane Raquel Motter, Sarah Nicole Hilmer, Vera Maria Vieira Paniz · 2019 · Frontiers in Pharmacology
34. Allium Jesdianum Extract Improve Acetaminophen-Induced Hepatic Failure through Inhibition of Oxidative/Nitrosative Stress
    Zohreh Sohrabinezhad, Dara Dastan, Sara Soleimani Asl, Amir Nili‐Ahmadabadi · 2019 · Journal of pharmacopuncture
35. Acetaminophen toxicity
    D. Adam Algren · 2020 · Elsevier eBooks
36. Dibenzazepine combats acute liver injury in rats via amendments of Notch signaling and activation of autophagy
    Lamiaa A. Ahmed, Rana H. Abd El‐Rhman, Amany M. Gad, Sherifa K. Hassaneen, Mohammed Farrag El-Yamany · 2020 · Naunyn-Schmiedeberg s Archives of Pharmacology
37. Engineered three-dimensional Au-Cu bimetallic dendritic nanosensor for ultrasensitive drug detection in urine samples and in vitro human embryonic kidney cells model
    Buddhadev Purohit, Ashutosh Kumar, Kuldeep Mahato, Ananya Srivastava, Pranjal Chandra · 2022 · Microchemical Journal
38. Detection of Acetaminophen in Groundwater by Laccase-Based Amperometric Biosensors Using MoS2 Modified Carbon Paper Electrodes
    Marcela Herrera-Domínguez, Koun Lim, Iris Aguilar-Hernández, Alejandra García‐García, Shelley D. Minteer, Nancy Ornelas‐Soto, Raúl García-Morales · 2023 · Sensors
39. Ethyl gallate concurrent administration protects against acetaminophen‐induced acute liver injury in mice: An in vivo and in silico approach
    Devaraj Ezhilarasan, Karthik Shree Harini, Munusamy Karthick, Chandrabose Selvaraj · 2023 · Chemical Biology & Drug Design
40. Update and Application of a Deep Learning Model for the Prediction of Interactions between Drugs Used by Patients with Multiple Sclerosis
    Michael Hecker, Niklas Frahm, Uwe Klaus Zettl · 2023 · Pharmaceutics
41. Phytic acid attenuates acetaminophen-induced hepatotoxicity via modulating iron-mediated oxidative stress and SIRT-1 expression in mice
    Hend M Hassan, Nehal H.M. Abdel-Halim, Ibrahim El-Shenbaby, Manar A. Helmy, Maha Osman Hammad, Ola A. Habotta, Eman Mohamad El Nashar, Mansour A. Alghamdi, Rashid A. Aldahhan, Khulood Mohammed Al-Khater et al. · 2024 · Frontiers in Pharmacology
42. The Effects of Diet, Dietary Supplements, Drugs and Exercise on Physical, Diagnostic Values of Urine Characteristics
    Dorota Skrajnowska, Barbara Bobrowska‐Korczak · 2024 · Nutrients
43. A Modular, Reconfigurable Microfabricated Assembly Platform for Microfluidic Transport and Multitype Cell Culture and Drug Testing
    Xin Xie, Sushila Maharjan, Sanwei Liu, Yu Shrike Zhang, Carol Livermore · 2019 · Micromachines
44. Hepatotoxicity-Induced by the Therapeutic Dose of Acetaminophen and the Ameliorative Effect of Oral Co-administration of Selenium/Tribulus terrestris Extract in Rats
    Amin Abdullah Al-Doaiss · 2020 · International Journal of Morphology
45. Inhibition of mitochondrial function: An alternative explanation for the antipyretic and hypothermic actions of acetaminophen
    Shazma Bashir, Winston A. Morgan · 2022 · Life Sciences
46. Anti-oxidative and anti-inflammatory benefits of the ribonucleoside analogue 5-azacitidine in mice with acetaminophen-induced toxic hepatitis
    Changming Yang, Yi Jun, Xianqiong Gong, Pu Ge, Jie Dai, Ling Lin, Yu Xing, Li Zhang · 2017 · International Immunopharmacology
47. Paracetamol poisoning: a population-based study from Iceland
    Friðriksdóttir, Þorbjörg Andrea, Jónsdóttir, Freyja, Snook, Curtis P., Líndal, Helena, Björnsson, Einar S. · 2021 · Scandinavian Journal of Gastroenterology
48. Enhancement of TEX264-Mediated ER-Phagy Contributes to the Therapeutic Effect of Glycycoumarin against APA Hepatotoxicity in Mice
    Mingzhu Yan, Zhi Wang, Tianji Xia, Suwei Jin, Yongguang Liu, Hongbo Hu, Qi Chang · 2021 · Biomedicines
49. Non-Intentional N-Acetylcysteine Overdose Associated with Cerebral Edema and Brain Death
    Emma E.M. Spence, Sey Shwetz, Lauren A. Ryan, Natalie R. Anton, Ari Robin Joffe · 2023 · Case Reports in Gastroenterology
50. A dual-ratiometric electrochemical sensor based on Cu/N-doped porous carbon derived from Cu-metal organic framework for acetaminophen determination
    Yujie Li, Xiaoli Liu, Jianbin Zheng · 2023 · Microchemical Journal
51. Selenium Ameliorates Acetaminophen-Induced Oxidative Stress via MAPK and Nrf2 Pathways in Mice
    Mylanayakanahosahalli Chandrashekar Indumathi, Kamatam Swetha, Kandahalli Venkataranganayaka Abhilasha, Shiva Siddappa, Shivamadhaiah Manjula Kumar, Govinda Keerthi Prasad, Chu‐Huang Chen, Gopal Kedihithlu Marathe · 2023 · Biological Trace Element Research
52. Generation and characterization of mature hepatocyte organoids for liver metabolic studies
    Yuchen Liu, Yaxing Zhou, James Ahodantin, Yu Jin, Juanjuan Zhu, Zhonghe Sun, Xiaolin Wu, Lishan Su, Yingzi Yang · 2024 · Journal of Cell Science
53. Paracetamol (acetaminophen) hepatotoxicity increases in the presence of an added herbal compound
    Susan M. Britza, Ian Musgrave, Roger W. Byard · 2020 · Legal Medicine
54. The impact of dimethyl sulfoxide on oxidative stress and cytotoxicity in various experimental models
    P. Dludla, B. Nkambule, S. Mazibuko-Mbeje, T. M. Nyambuya, S. Silvestri, Patrick Orlando, Vuyolwethu Mxinwa, J. Louw, Luca Tiano · 2021 · Elsevier eBooks
55. Metabolomic markers predictive of hepatic adaptation to therapeutic dosing of acetaminophen
    Brandon Sonn, Kennon J Heard, Susan M. Heard, Angelo D’Alessandro, Kate M. Reynolds, Richard C. Dart, Barry H. Rumack, Andrew A. Monte · 2021 · Clinical Toxicology
56. Trimethylamine N‐oxide exacerbates acetaminophen‐induced liver injury by interfering with macrophage‐mediated liver regeneration
    Mingzhu Yan, Chong Zhao, Shangyun Lu, Jinling Cui, Zhenou Sun, Xiaoyi Liu, Shuo Liu, Yazhen Huo, Shutao Yin, Hongbo Hu · 2021 · Journal of Cellular Physiology
57. Impact of Liver Functions by Repurposed Drugs for COVID-19 Treatment
    Rongzhi Zhang, Qiang Wang, Jianshe Yang · 2022 · Journal of Clinical and Translational Hepatology
58. Ginseng for Liver Injury: Friend or Foe?
    Tae‐Woo Kim · 2016 · Medicines
59. Noninvasive Imaging of Drug-Induced Liver Injury with 18F-DFA PET
    Jessica R. Salas, Bao Ying Chen, Alicia Wong, Sérgio M. Duarte, Stephanie Angarita, Gerald S. Lipshutz, Owen N. Witte, Peter M. Clark · 2018 · Journal of Nuclear Medicine
60. A comparison of 4-year total medical care costs, adverse outcomes, and opioid/prescription analgesic use for 3 knee osteoarthritis pain treatments: Intra-articular hyaluronic acid, intra-articular corticosteroids, and knee arthroplasty
    John I. Mackowiak, John T. Jones, Vinod Dasa · 2020 · Seminars in Arthritis and Rheumatism
61. Role of Nutraceuticals in COVID-19 Mediated Liver Dysfunction
    Mohammed Sikander, Shabnam Malik, Anyssa Rodriguez, Murali Mohan Yallapu, Acharan Singh Narula, Sanjaya Kumar Satapathy, Vijian Dhevan, Subhash C. Chauhan, Meena Jaggi · 2020 · Molecules
62. Insight into CuX (CuO, Cu2O, and CuS) for enhanced performance of CuX/g-C3N4 nanocomposites-based acetaminophen electrochemical sensors
    Yao Chen, Yanyan Zhu, Yuhui Zhao, Jing Wang, Meng Li · 2020 · Microchemical Journal
63. Targeted Mitochondrial Delivery to Hepatocytes: A Review
    Brent D. Heineman, Xiaocong Liu, George Y. Wu · 2021 · Journal of Clinical and Translational Hepatology
64. Unveiling the molecular basis of paracetamol-induced hepatotoxicity: Interaction of N-acetyl-p-benzoquinone imine with mitochondrial succinate dehydrogenase
    Md Sahadot Hossen, Adiba Akter, Mahir Azmal, Mostakim Rayhan, Kazi Saiful Islam, Md Mahmodul Islam, Shamim Ahmed, Mohammad Abdullah-Al-Shoeb · 2024 · Biochemistry and Biophysics Reports
65. Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway
    Clàudia Gil‐Pitarch, Marina Serrano‐Maciá, Jorge Simón, Laura Mosca, Carolina Conter, Claudia M. Rejano-Gordillo, Leidy Estefanía Zapata-Pavas, Patricia Peña-Sanfélix, Mikel Azkargorta, Rubén Rodríguez Agudo et al. · 2024 · Cell Reports Medicine
66. Discovery and structure-activity relationship of auriculatone: A potent hepatoprotective agent against acetaminophen-induced liver injury
    Meng Zhou, Min Wang, Rui-Feng Zhong, Xiang-Ming Liao, Lianli Deng, Guo‐Bo Xu, Xun Jun He, Jing Li, Yongjun Li, Ting Liu et al. · 2017 · Bioorganic & Medicinal Chemistry Letters
67. Aqueous Partition of Methanolic Extract of Dicranopteris linearis Leaves Protects against Liver Damage Induced by Paracetamol
    Zainul Amiruddin Zakaria, Farah Hidayah Kamisan, Nurliana Nasir, Lay Kek Teh, Mohd Zaki Salleh · 2019 · Nutrients
68. Toxins mechanism in instigating hepatotoxicity
    Sangeetha Nithiyanandam, Sabina Evan Prince · 2020 · Toxin Reviews
69. Promising Porous Carbon Material Derived from Argan Paste Cake by KOH Activation, for Paracetamol Removal
    El Habib Yahia, El Khalil Cherif, Mohammed Ouzzine, Abdellah Touijer, Franco Coren, Mohamed Saidi · 2023 · Processes
70. Medication Reviews by a Clinical Pharmacist at an Irish University Teaching Hospital
    Alan Kearney, Ciaran Halleran, Elaine K. Walsh, Derina Byrne, Jennifer Haugh, Laura Jane Sahm · 2017 · Pharmacy
71. Pooled Dosing and Efficacy Analysis of the Sufentanil Sublingual Tablet 30 mcg Across Demographic Subgroups for the Management of Moderate-to-Severe Acute Pain
    Jacob L. Hutchins, David G. Leiman, Zubaid Rafique, Karen P. DiDonato, Pamela Pierce Palmer · 2019 · Journal of PeriAnesthesia Nursing
72. Is There an Increased Risk of Hepatotoxicity with Metamizole? A Comparative Cohort Study in Incident Users
    Karin Hedenmalm, Alexandra C. Pacurariu, Jim Slattery, Xavier Kurz, Gianmario Candore, Rob Flynn · 2021 · Drug Safety
73. Antioxidant Extract from Cleistocalyx nervosum var. paniala Pulp Ameliorates Acetaminophen-Induced Acute Hepatotoxicity in Rats
    Arpamas Chariyakornkul, Waristha Juengwiroj, Jetsada Ruangsuriya, Rawiwan Wongpoomchai · 2022 · Molecules
74. Platanosides, a Potential Botanical Drug Combination, Decrease Liver Injury Caused by Acetaminophen Overdose in Mice
    Devadoss J. Samuvel, Nga T. Nguyen, Hartmut Jaeschke, John J. Lemasters, Xiaojuan Wang, Yeun‐Mun Choo, Mark T. Hamann, Zhi Zhong · 2022 · Journal of Natural Products
75. Tangeretin and 4′-demethyltangeretin prevent damage to mouse hepatocytes from oxidative stress by activating the Nrf2-related antioxidant pathway via an epigenetic mechanism
    Zheng‐Yuan Su, Jen-Chun Chien, Yen‐Chen Tung, Tien‐Yuan Wu, Jie‐An Liao, Guor-Jien Wei · 2023 · Chemico-Biological Interactions
76. Idiosyncratic DILI and RUCAM under One Hat: The Global View
    Rolf Teschke, Gaby Danan · 2023 · Livers
77. Deciphering Acetaminophen-Induced Hepatotoxicity: The Crucial Role of Transcription Factors like Nuclear Factor Erythroid 2–Related Factor 2 as Genetic Determinants of Susceptibility to Drug-Induced Liver Injury
    Ankit Pravin Laddha, Hangyu Wu, José Enrique Manautou · 2024 · Drug Metabolism and Disposition
78. Acetaminophen Overdose Reveals PAR4 as a Low-Expressing but Potent Receptor on the Hepatic Endothelium in Mice
    Rahul Rajala, Audrey C. A. Cleuren, Courtney T. Griffin · 2024 · Arteriosclerosis Thrombosis and Vascular Biology
79. Internet pseudoscience: Testing opioid containing formulations with tampering potential
    Jennifer Paola Pascali, Paolo Fais, Fabio Vaiano, Nicola Pigaiani, Stefano D’Errico, Sandra Furlanetto, Diego Palumbo, Elisabetta Bertol · 2018 · Journal of Pharmaceutical and Biomedical Analysis
80. Undue Elevation of Procalcitonin in Pediatric Paracetamol Intoxication is Not Explained by Liver Cell Injury Alone
    Eva Tschiedel, Roland Assert, Ursula Felderhoff‐Müser, Simone Kathemann, Oliver Witzke, Peter F. Hoyer, Christian Dohna‐Schwake · 2018 · Annals of Hepatology
81. Acetaminophen toxicity induces mitochondrial complex I inhibition in human liver tissue
    Karoline Maise Chrøis, Steen Larsen, Julie Steen Pedersen, Marte Opseth Rygg, Astrid E. B. Boilesen, Flemming Bendtsen, Flemming Dela · 2019 · Basic & Clinical Pharmacology & Toxicology
82. Acute acetaminophen toxicity in adults
    Scott J. Saccomano · 2019 · Nursing Critical Care
83. National Poison Center Calls Before vs After Availability of High-Dose Acetaminophen (Paracetamol) Tablets in Switzerland
    Adrián Martínez-De la Torre, Stefan Weiler, Dominic Stefan Bräm, Samuel Sebastian Allemann, Hugo Kupferschmidt, Andrea Michelle Burden · 2020 · JAMA Network Open
84. Mitochondrial versus microsomal bioactivation of paracetamol by human liver and kidney tissues
    Ege Arzuk, Mehmet Tokdemır, Hi̇lmi̇ Orhan · 2022 · Toxicology Letters
85. Moderate-Intensity Ultrasound-Triggered On-Demand Analgesia Nanoplatforms for Postoperative Pain Management
    Xinye Song, Mengxiao Luan, Weiyi Zhang, Ruizheng Zhang, Li Xue, Yong Luan · 2022 · International Journal of Nanomedicine
86. Acute liver injury in COVID-19 patients hospitalized in the intensive care unit: Narrative review
    Effie Polyzogopoulou, Pinelopi Amoiridou, Theodore P. Abraham, Ioannis Ventoulis · 2022 · World Journal of Gastroenterology
87. The Evolving Landscape of Acute Pain Management in the Era of the Opioid Crisis
    Ali Pourmand, Gregory N. Jasani, Courtney Shay, Maryann E. Mazer-Amirshahi · 2018 · Current Pain and Headache Reports
88. In Vitro Antioxidant Activities and the Therapeutic Potential of Some Newly Synthesized Chalcones Against 4-Acetaminophenol Induced Hepatotoxicity in Rats
    Muhammad Shoaib Akhtar, Azizur Rehman, Haroon Arshad, Abdul Malik, Muheer Fatima, Tahira Tabassum, Abdul Rauf Raza, Munnaza Bukhsh, Mian Anjum Murtaza, Malik Hassan Mehmood et al. · 2021 · Dose-Response
89. Silicon Doped Boron Carbide (BC3) Nanosheet as a Promising Sensitive Material for Detection of Acetaminophen Drug Based on the DFT Approach
    Mengchan Wang, Canhui Tang · 2021 · Silicon
90. Metformin as a protective agent against natural or chemical toxicities: a comprehensive review on drug repositioning
    Seyed Elyas Meshkani, Davood Mahdian, Kazem Abbaszadeh‐Goudarzi, Mina Abroudi, Ghazaleh Dadashizadeh, Jean‐Daniel Lalau, Marc E. De Broe, Hossein Hosseinzadeh · 2019 · Journal of Endocrinological Investigation
91. Caesalpinia bonducella Counteracts Paracetamol-Instigated Hepatic Toxicity via Modulating TNF-α and IL-6/10 Expression and Bcl-2 and Caspase-8/3 Signalling
    Sangeetha Nithiyanandam, Sabina Evan Prince · 2023 · Applied Biochemistry and Biotechnology
92. Hepatic Sirt6 activation abrogates acute liver failure
    Jinque Luo, Huan Liu, Yanni Xu, Nanhui Yu, Rebbeca Steiner, Xiaoqian Wu, Shuyi Si, Zheng Gen Jin · 2024 · Cell Death and Disease
93. The multiple mechanisms and modes of cell death after acetaminophen overdose
    Hartmut Jaeschke, Anup Ramachandran · 2025 · Exploration of Digestive Diseases
94. Macrophage PKM2 depletion ameliorates hepatic inflammation and acute liver injury in mice
    Ziwei Kang, Ruoyan Xie, Yiming Cui, Zhiwei Chen, Jincheng Li, Jinyu Lv, Weijia Ye, Peixin Zhao, Keke Zhang, Jian Hong et al. · 2025 · Frontiers in Pharmacology
95. Molecular docking and pharmacological/toxicological assessment of a new compound designed from celecoxib and paracetamol by molecular hybridization
    Daiany Priscilla Bueno da Silva, Iziara Ferreira Florentino, Dayane M. da Silva, Roberta Campos Lino, Carina Sofia Cardoso, Lorrane Kelle da Silva Moreira, Géssica Adriana Vasconcelos, Daniela Cristina Vinhal, Anna C. D. Cardoso, Bianca Villavicencio et al. · 2018 · Inflammopharmacology
96. Gene Expression Signatures in AML-12 Hepatocyte Cells upon Dengue virus Infection and Acetaminophen Treatment
    Jorge Gomes Goulart Ferreira, Sandra Grossi Gava, Eneida Santos de Oliveira, Izabella Cristina Andrade Batista, Gabriel da Rocha Fernandes, Marina de Moraes Mourão, Carlos Eduardo Calzavara-Silva · 2020 · Viruses
97. Common Selfcare Indications of Pain Medications in Children
    William T. Zempsky, John A Bell, Vanessa Maria Mossali, Preeti Kachroo, Kamran Siddiqui · 2023 · Pediatric Drugs
98. Insight into COVID-19 associated liver injury: Mechanisms, evaluation, and clinical implications
    Nosheen Nasir, Iffat Khanum, Kiren Habib, Abdullah Wagley, Aleena Arshad, Atif Majeed · 2024 · Hepatology forum/Hepatology forum (Online)
99. Paracetamol Misuse and Dental Pain: Results from the French Observational DAntaLor Study
    Elise Pape, Claire Collin, F. Camelot, Lucie Javot, Nadine Petitpain, Emmanuel Puskarczyk, Daniel Anastasio, Éric Gérard, Nicolas Gambier, Julien Scala‐Bertola et al. · 2019 · Journal of Oral & Facial Pain and Headache
100. An Unexpected Role of Cholesterol Sulfotransferase and its Regulation in Sensitizing Mice to Acetaminophen-Induced Liver Injury
     Yunqi An, Pengcheng Wang, Pengfei Xu, Hung‐Chun Tung, Yang Xie, Levent Kirisci, Meishu Xu, Songrong Ren, Xin Tian, Xiaochao Ma et al. · 2019 · Molecular Pharmacology