Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update

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Items 301–400 of 744

1. A Quality Improvement Project to Reduce Combination Acetaminophen-opioid Prescriptions to Pediatric Orthopedic Patients
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2. Comparison of ameliorative effects ofTaraxacum syriacumand N-acetylcysteine against acetaminophen-induced oxidative stress in rat liver and kidney
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3. The effect of nutritional status on the pharmacokinetic profile of acetaminophen
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4. Artificial Intelligence-Assisted Image Analysis of Acetaminophen-Induced Acute Hepatic Injury in Sprague-Dawley Rats
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5. Pulmonary implications of acetaminophen exposures independent of hepatic toxicity
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6. New in vitro screening system to detect drug-induced liver injury using a culture plate with low drug sorption and high oxygen permeability
   Akinori Takemura, Sanae Ishii, Yugo Ikeyama, Katsuhiro Esashika, Jun Takahashi, Kousei Ito · 2023 · Drug Metabolism and Pharmacokinetics
7. Calcitriol Protects against Acetaminophen-Induced Hepatotoxicity in Mice
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8. Electrochemical Detection of Acetaminophen in Pharmaceuticals Using Rod-Shaped α-Bi2O3 Prepared via Reverse Co-Precipitation
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9. Genomics Testing and Personalized Medicine in the Preoperative Setting
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10. MRI-based preclinical discovery of DILI: A lesson from paracetamol-induced hepatotoxicity
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11. The potential role of sestrin 2 in liver regeneration
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12. Role of immune dysfunction in drug induced liver injury
    Chandrashekaran Girish, Sukumaran Sanjay · 2021 · World Journal of Hepatology
13. Oxidative stress mediates end-organ damage in a novel model of acetaminophen-toxicity in Drosophila
    Bejan Jon Saeedi, Sarah Hunter-Chang, Liping Luo, Kaiyan Li, Ken Liu, Brian Scott Robinson · 2022 · Scientific Reports
14. Investigation of Paracetamol Entrapped Nanoporous Silica Nanoparticles in Transdermal Drug Delivery System
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15. Symmetry-breaking charge-transfer enables turn-on fluorescence sensing in the shortwave infrared spectral region for in vivo vasculature redox homeostasis
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16. Real-world impact of the high concentration non-avian high molecular weight hyaluronan on pain medication use among osteoarthritis patients
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17. Genomics Testing and Personalized Medicine in the Preoperative Setting
    Rodney Allanigue Gabriel, Brittany Nicole Burton, Richard D. Urman, Ruth S. Waterman · 2019 · Surgical Oncology Clinics of North America
18. PYP1‑4 peptide from Pyropia yezoensis protects against acetaminophen‑induced hepatotoxicity in HepG2 cells
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19. PBPK modeling of CYP3A and P-gp substrates to predict drug–drug interactions in patients undergoing Roux-en-Y gastric bypass surgery
    Kuan‐Fu Chen, Lingtak‐Neander Chan, Yvonne S. Lin · 2020 · Journal of Pharmacokinetics and Pharmacodynamics
20. Biofunctional significance of multi-herbal combination against paracetamol-induced hepatotoxicity in Wistar rats
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21. Molecular Dynamics Simulations of Protein–Drug Complexes: A Computational Protocol for Investigating the Interactions of Small-Molecule Therapeutics with Biological Targets and Biosensors
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22. Diagnosis of acute intoxications in critically ill patients: focus on biomarkers – part 1: epidemiology, methodology and general overview
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23. Understanding toxicology: mechanisms and applications
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24. Neutralizing serum amyloid a protects against sinusoidal endothelial cell damage and platelet aggregation during acetaminophen-induced liver injury
    You, Kai, Wang, Yan, Chen, Xiaoxia, Yang, Zhen, Chen, Yan, Tan, Shenglin, Tao, Jiawang, Getachew, Anteneh, Pan, Tingcai, Xu, Yingying et al. · 2023 · Biochemical and Biophysical Research Communications
25. Safety in Acute Pain Medicine—Pharmacologic Considerations and the Impact of Systems-Based Gaps
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26. Analgesic efficacy of nefopam for cancer pain: a randomized controlled study
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27. APAP-Induced IκBβ/NFκB Signaling Drives Hepatic Il6 Expression and Associated Sinusoidal Dilation
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28. Phellinus linteus polysaccharides mediates acetaminophen-induced hepatotoxicity via activating AMPK/Nrf2 signaling pathways
    Lilei Zhao, Lianwen Zheng, Zheng Li, Meiyu Jin, Qi Wang, Jiaqi Cheng, Jinxia Li, Haihua Feng · 2022 · Aging
29. Loss of microRNA-21 protects against acetaminophen-induced hepatotoxicity in mice
    Alexandra M Huffman, Maryam Syed, Samar Rezq, Christopher D. Anderson, Licy L. Yanes Cardozo, Damián G. Romero · 2023 · Archives of Toxicology
30. Drug-Induced Liver Toxicity
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31. A web-based histology atlas for the freshwater sentinel species Daphnia magna
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32. Effect of hemolysis, icterus, and lipemia on three acetaminophen assays: Potential medical consequences of false positive results
    Y. Victoria Zhang, Shu‐Ling Fan, Mark D. Kellogg · 2018 · Clinica Chimica Acta
33. Strategic approach in hepatic delivery of andrographolide: Key challenges and new insights
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34. Joint Inflammation: Insights of Osteoarthritis, Gouty and Rheumatoid Arthritis and its Prevalence, Mechanism, Medications and Remedies
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35. Forensic Aspects of a Fatal Intoxication Involving Acetaminophen, Citalopram and Trazodone: A Case Report
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36. Water extract of lotus leaves has hepatoprotective activity by enhancing Nrf2- and epigenetics-mediated cellular antioxidant capacity in mouse hepatocytes
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37. Liver Transplantation for Acetaminophen-Induced Acute Liver Failure: Role of Psychiatric Comorbidity in Listing Decisions and Outcomes
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38. Dose Can Help to Achieve Effective Pain Relief for Acute Mild to Moderate Pain with Over-the-Counter Paracetamol
    Gaul, Charly, Eschalier, Alain · 2018 · The Open Pain Journal
39. Antioxidant, hepatoprotective & nephroprotective potential of a novel synthetic compound 2′, 3′-dihydroxybenzylidene in paracetamol intoxicated rats
    Mohammad Attaullah, Aziz Ullah, Muhammad M. Hussain, Muhammad Zahoor, Riaz Ullah, Essam A. Ali, Ateeq Ur Rahman, Arif Jan · 2023 · Heliyon
40. Adenosine kinase protects against acetaminophen-induced acute liver injury by activating autophagy in hepatocytes
    Chuanxin Zhang, Xuehao Liu, Xilong Liu, Rui Hua, Han Liu, Jiaxin Ma, Dan Zou, Guangmei Wang, Qiuhuan Yuan, Bailu Wang et al. · 2024 · Cell Biology and Toxicology
41. Inhibition of mitochondrial complex I by rotenone protects against acetaminophen-induced liver injury.
    Xuhua Ge, Hua Hu, Peipei Wang, Jiaqi Liu, Yue Zhang, Guixia Ding, Chunhua Zhu, Songming Huang, Zhanjun Jia, Aihua Zhang · 2019 · Europe PMC (PubMed Central)
42. Antioxidant and chemoprotective peptides from simulated gastrointestinal digested (SGID) protein hydrolysate of Pyropia yezoensis against acetaminophen-induced HepG2 cells
    Selvakumari Ulagesan, Tae-Kil Eom, Taek‐Jeong Nam, Youn‐Hee Choi · 2022 · Bioprocess and Biosystems Engineering
43. Meat tenderization using acetaminophen (paracetamol/APAP): A review on deductive biochemical mechanisms, toxicological implications and strategies for mitigation
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44. Hepatoprotective properties of water kefir: A traditional fermented drink and its potential role
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45. Nexus of COVID-19 Crises and Health Care Performance in Jordan: The Moderation Role of Telemedicine, Innovation, and Infrastructure
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46. Iguratimod, an allosteric inhibitor of macrophage migration inhibitory factor (MIF), prevents mortality and oxidative stress in a murine model of acetaminophen overdose
    Joshua Bloom, Georgios Pantouris, Mingzhu He, Bayan Aljabari, Lopa Mishra, R. Manjula, Andrew Parkins, Elias Lolis, Yousef Al‐Abed · 2024 · Molecular Medicine
47. Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors
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48. Metformin-Induced Lactic Acidosis: A Case Study
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49. Use of a Bile Salt Export Pump Knockdown Rat Susceptibility Model to Interrogate Mechanism of Drug-Induced Liver Toxicity
    Yutai Li, Raymond Evers, Michael J. Hafey, Kyeongmi Cheon, Hong Duong, Donna Lynch, Lisa LaFranco-Scheuch, Stephen J. Pacchione, Alex M. Tamburino, Keith Quincy Tanis et al. · 2019 · Toxicological Sciences
50. Überlegungen zum perioperativen Einsatz von Metamizol
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51. At-a-glance - Trends in emergency department visits for acetaminophen-related poisonings: 2011–2019
    Jaskiran Kaur, Steven R McFaull, Felix Bang · 2020 · Health Promotion and Chronic Disease Prevention in Canada
52. Ecto-Nucleotide Triphosphate Diphosphohydrolase-2 (NTPDase2) Deletion Increases Acetaminophen-Induced Hepatotoxicity
    Linda Feldbrügge, Katrin Splith, Ines Kämmerer, Sandra Richter, Anna Riddermann, Santiago Andres Ortiz Galindo, Felix Krenzien, Tobias Müller, Eva Csizmadia, Johann Pratschke et al. · 2020 · International Journal of Molecular Sciences
53. Effectiveness of scheduled intravenous acetaminophen in the postoperative pain management of video-assisted thoracic surgery
    Yoshinobu Shikatani, Junichi Soh, Kazuhiko Shien, Takeshi Kurosaki, Shinji Ohtani, Hiromasa Yamamoto, Arata Taniguchi, Mikio Okazaki, Seiichiro Sugimoto, Masaomi Yamane et al. · 2020 · Surgery Today
54. Fructose Protects Against Acetaminophen‐Induced Hepatotoxicity Mainly by Activating the Carbohydrate‐Response Element‐Binding Protein α–Fibroblast Growth Factor 21 Axis in Mice
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55. Drug toxicity and forensic pharmacokinetics
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56. Prooxidant activity of aminophenol compounds: copper-dependent generation of reactive oxygen species
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57. Activation of the adenosine A2B receptor even beyond the therapeutic window of N-acetylcysteine accelerates liver recovery after an acetaminophen overdose
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58. Hepatoprotective Effect of Coenzyme Q10 in Rats with Diclofenac Toxicity.
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59. Divergent effects of glutathione depletion on isocitrate dehydrogenase 1 and the pentose phosphate pathway in hamster liver
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60. Has the time come to stop routine N‐acetylcysteine treatment in young children in Denmark? A review of 300 suspected paracetamol overdoses in children aged 0–6 years
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61. Intraoperative Anesthetic Strategies to Mitigate Early Allograft Dysfunction After Orthotopic Liver Transplantation: A Narrative Review
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62. Novel reduced heteropolyacid nanoparticles for effective treatment of drug-induced liver injury by manipulating reactive oxygen and nitrogen species and inflammatory signals
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63. SETDB1 promotes mammalian liver regeneration by stimulating cytokine CSF3 in hepatocytes
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64. Sumc (Rhus coriaria L.) fruit ameliorates paracetamol-induced hepatotoxicity
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65. High-Dose Acetaminophen as a Treatment for Cancer
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66. The thrombopoietin mimetic JNJ-26366821 reduces the late injury and accelerates the onset of liver recovery after acetaminophen-induced liver injury in mice
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67. Loss of Ninjurin1 alleviates acetaminophen-induced liver injury via enhancing AMPKα-NRF2 pathway
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68. Mitigating Post-Operative Dental Pain:
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69. Impact of malnourishment on the pharmacokinetics of acetaminophen and susceptibility to acetaminophen hepatotoxicity
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70. DRUG INDUCED LIVER INJURY;
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71. Acacia sieberiana (Fabaceae) attenuates paracetamol and Bile Duct Ligation-Induced hepatotoxicity via modulation of biochemical and oxidative stress biomarkers
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73. Liver injury associated with Acetaminophen: A Review
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74. Association between acetaminophen metabolites and CYP2E1 DNA methylation level in neonate cord blood in the Boston Birth Cohort
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75. The Modulation of Phospho-Extracellular Signal-Regulated Kinase and Phospho-Protein Kinase B Signaling Pathways plus Activity of Macrophage-Stimulating Protein Contribute to the Protective Effect of Stachydrine on Acetaminophen-Induced Liver Injury
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76. CLEC-1 Restrains Acute Inflammatory Response and Recruitment of Neutrophils following Tissue Injury
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77. Anti-Oxidant Drugs: Novelties and Clinical Implications in Cerebellar Ataxias
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78. Methanol, Paracetamol Toxicities and Acute Blindness
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79. First Case Report of Fulminant Hepatitis After Laparoscopic Sleeve Gastrectomy Associated with Concomitant Maximal Therapeutic Dose of Acetaminophen Use, Protein Calorie Malnutrition, and Vitamins A and D, Selenium, and Glutathione Deficiencies
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80. Management of acetaminophen toxicity, a review
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81. Paracetamol dosing in hospital and on discharge for older people who are frail or have low body weight
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82. Tea (Camellia sinensis L. Kuntze) as Hepatoprotective Agent
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83. Neonatal Pain Management
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84. Mitochondrial Dysfunction in Drug‐Induced Liver Injury
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85. Using different zebrafish models to explore liver regeneration
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86. Hepatotoxicity evaluation of cannabidiol, cannabinol, cannabichromene and cannabigerol using a human quad culture liver chip
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87. CpG-oligodeoxynucleotides challenged macrophages ameliorate acetaminophen induced liver injury by activating TLR9/IRG1/itaconate metabolic pathway
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88. An international survey of the treatment of massive paracetamol overdose in 2023
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89. Therapeutic potentials of N‐acetylcysteine immobilized polyrhodanine nanoparticles toward acetaminophen‐induced acute hepatotoxicity in rat
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91. An activatable β-diketonate europium(III) complex-based probe for time-gated luminescence detection and imaging of peroxynitrite in vitro and in vivo
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92. Preformulation Study of Pugun Tano (Curanga fel-terrae [Lour.] Merr) Ethanolic Extract Granule Mass in Capsule as Hepatoprotective Drug
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93. Drugs-Inducing Hepatotoxicity
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95. Concurrent administration of acetaminophen and ethanol: impact on mouse liver and testis
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96. The anti-nociceptive effects of ethanol extract of aerial parts of Schkuhria pinnata in mice
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97. Adverse events associated with analgesics: A focus on paracetamol use
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98. Quantity changes in acute headache medication use among patients with chronic migraine treated with eptinezumab: subanalysis of the PROMISE-2 study
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99. A systematic review on hepatoprotective potential of grape and polyphenolic compounds: molecular mechanism and future prospective
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100. Safety, tolerability and pharmacokinetics of forsythin in healthy subjects: a double-blinded, placebo-controlled single-dose and multiple-dose escalation and food effect study
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