The feasibility of a clinical trial of pain related to temporomandibular muscle and joint disorders
Open accessAbstract
Background This survey characterized the strategies used by general dentists to manage temporomandibular muscle joint disorders (TMJD) pain, and assessed the feasibility of doing a randomized clinical trial (RCT) of the effectiveness of these strategies. Methods Dentists from three Practice-Based Research Networks (PBRNs) specifically, DPBRN, PEARL, NWPRECEDENT) accepted to participate in this survey. Results Out of 862 dentists surveyed, 654 were general dentists who treat TMJD; among these, 80.3 percent stated they would participate in a RCT. Dentists treated an average of three pain-related TMJD patients per month. Splints (97.6 percent), self-care (85.9 percent) and over-the-counter or prescribed medications (84.6 percent) were the treatments most frequently used. The preferred treatments to compare in a RCT were splint therapy (35.8 percent), self-care (27.4 percent) and medications (16.9 percent). Conclusions Most general dentists treat TMJD pain, and reversible initial care is typically provided. Finally, it is feasible to conduct a RCT in the PBRNs to assess the effectiveness of splint therapy, medications and/or self-care, for the initial management of painful TMJD. Clinical Implications There is an opportunity to do a RCT in PBRNs leading to the development of evidence-based treatment guidelines for the initial treatment of pain-related TMJD by primary care dentists.
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The Japanese network JDPBRN has also been involved in some studies in partnership with the American NDPBRN.
“In addition, the Japanese network JDPBRN has also been involved in some studies in partnership with the American NDPBRN [34].”
From Dental Practice-Based Research Networks (D-PBRN) worldwide: a scoping review. (2021) · cites this paper as [34]
The Introduction describes DPBRN as a network of practices in the United States and Scandinavia, and the Methods identify DPBRN, PEARL, and PRECEDENT as the networks in this survey (page numbers unavailable). Searches for JDPBRN, Japan, and a partnership with NDPBRN found no passage addressing the claimed Japanese–American collaboration. (LLM, conf=0.76)
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Self-citation
- Authors
- Velly, A. M., Schiffman, E. L., Rindal, D. B., Cunha-Cruz, J., Gilbert, G. H., Lehmann, M., Horowitz, A., & Fricton, J.
- Affiliations
- Jewish General Hospital (CA)
- Corresponding author
- Velly, Ana M.
- Venue
- The Journal of the American Dental Association
- Publisher
- Elsevier BV
- Published
- 2013-01
- Volume
- 144
- Issue
- 1
- Pages
- e01-e10
- ISSN
- 0002-8177 (ISSN-L)
- PMC
- PMC3539212
- OpenAlex
- W171169037
- Semantic Scholar
- 7fda380d169831921eafd655247034ad11ad3d8b
- Cited by
- 31
- References
- 35
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 4 · 2023: 2 · 2022: 1 · 2021: 3 · 2020: 4 · 2019: 3 · 2018: 3 · 2017: 4 · 2016: 1 · 2015: 3
- FWCI
- 2.18
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- The Journal of the American Dental Association (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Dental and Craniofacial Research (U01-DE-16750, U01-DE-16746, U01DE016752, U01DE016746, U01-DE-16755, U01DE016754, U01-DE-16752, U19-DE-22516, U01DE016750, U01‐DE‐16747, U01‐DE‐16754, U01DE016755, U01DE016747, U19DE022516)
- Topics
- Health Sciences › Health Professions › Complementary and Manual Therapy › Temporomandibular Joint Disorders
- Health Sciences › Health Professions › General Health Professions › Health Sciences Research and Education
- Health Sciences › Dentistry › Periodontics › Scientific and Engineering Research Topics
- Keywords
- temporomandibular disorders, temporomandibular joint pain, general dentists, splint therapy, mouthguards, self-care, medication management, dental practice-based research network, evidence-based treatment guidelines
- MeSH terms
- Analgesics, Anti-Inflammatory Agents, Non-Steroidal, Antidepressive Agents, Tricyclic, Attitude of Health Personnel, Dentists, Nonprescription Drugs, Facial Pain, Feasibility Studies, Female, General Practice, Dental, Headache, Humans, Male, Middle Aged, Mouth Protectors, Primary Health Care, Surveys and Questionnaires, Scandinavian and Nordic Countries, Self Care, Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome, United States, Randomized Controlled Trials as Topic, Treatment Outcome, Occlusal Splints, Dental Research, Prescription Drugs, Community-Based Participatory Research
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