Metabolic responses to acute sprint interval exercise training performed after an oral 75‐gram glucose load in individuals with overweight/obesity
Open accessAbstract
There is evidence supporting that acute sprint interval training (SIT) might improve metabolic responses to postprandial glucose, but results are inconclusive. The aim of the present study was to explore the effects of acute SIT on metabolic response and substrate utilization in individuals with overweight/obesity after an oral 75‐gram glucose challenge. Thirty‐three participants with overweight/ obesity (32.7 ± 8.3 years, 24 male, 9 female) participated in the study and a crossover design was followed. After the 75‐gram glucose load, participants were randomly allocated to two groups: no exercise (resting) or SIT protocol. Metabolic data including respiratory quotient (RQ) and substrate utilization rates (fats and carbohydrates) were collected using the COSMED Q‐NRG + ® calorimeter. The RQ was significantly lower in the acute SIT group (0.76 [0.01];p < 0.0001) than in the resting group (0.80 [0.01];p = 0.036) at the 120‐min postprandial time point, and the RQ area under the curve (AUC) was also lower in the SIT group (mean difference of −6.62, 95% CI −12.00 to −1.24;p = 0.0161). The contribution of fat to energy expenditure increased after SIT during the postprandial period whereas the contribution of carbohydrates decreased. The AUC for fat contribution was significantly higher (mean difference 2311.9, 95% confidence interval [CI] 578.8 to 4043.3;p = 0.0098) and the AUC for carbohydrate contribution was significantly lower (mean difference −2283.1, 95% CI −4040.2 to −527.1;p = 0.0117) in the SIT group than in the resting group. In conclusions, acute SIT might have a positive effect on metabolic responses to postprandial glucose and, accordingly, should be recommended for improving metabolism in people with overweight/obesity.
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High-intensity exercise induces a greater reduction in RQ.
“with high-intensity exercise induce a greater reduction in RQ [39, 40].”
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- Authors
- Carrillo‐Arango, H. A., Atencio‐Osorio, M. A., López‐Álban, C. A., Nava‐González, E. J., Correa‐Rodríguez, M., Izquierdo, M., & Ramírez‐Vélez, R.
- Affiliations
- Grupo de Investigación en Deporte de Rendimiento (GRINDER), Programa de Educación Física y Deporte Universidad del Valle Cali Colombia
- Universidad del Valle (CO)
- Universidad Autónoma de Nuevo León (MX)
- Universidad de Granada (ES)
- Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA) Pamplona España
- Universidad Pública de Navarra (UPNA) (ES)
- Corresponding author
- Ramírez‐Vélez, Robinson
- ORCID
- Venue
- Physiological Reports
- Publisher
- Wiley
- Published
- 2023-01
- Volume
- 11
- Issue
- 2
- Pages
- e15555-e15555
- ISSN
- 2051-817X (ISSN-L)
- PMC
- PMC9875746
- OpenAlex
- W4317937888
- Cited by
- 10
- References
- 60
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 1 · 2023: 2
- FWCI
- 3.06
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Physiological Reports (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Academica-e (Universidad Pública de Navarra) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Greater South Information System
- Funders
- Universidad del Valle
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- sprint interval training, acute exercise, postprandial blood glucose, overweight, obesity, respiratory quotient, substrate utilization, fat oxidation, carbohydrate oxidation, energy expenditure, glucose tolerance
- MeSH terms
- High-Intensity Interval Training, Blood Glucose, Female, Glucose, Humans, Male, Obesity, Exercise, Postprandial Period, Overweight
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