Lung Extracellular Matrix and Fibroblast Function

Matrix elasticity directs stem cell lineage specification

Engler, A. J., Sen, S., Sweeney, H. L., & Discher, D. E. (2006) · Cell · doi:10.1016/j.cell.2006.06.044 · Cited by 13,915 · see citing works

Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin

Aziz, J., Shezali, H., Radzi, Z., Yahya, N. A., Abu Kassim, N. H., Czernuszka, J., & Rahman, M. T. (2016) · Skin Pharmacology and Physiology · doi:10.1159/000447017 · Cited by 7,323 · see citing works

Tissue Cells Feel and Respond to the Stiffness of Their Substrate

Discher, D. E., Janmey, P., & Wang, Y.-L. (2005) · Science · doi:10.1126/science.1116995 · Cited by 6,382 · see citing works

Reconstituting organ-level lung functions on a chip

Huh, D., Matthews, B. D., Mammoto, A., Montoya-Zavala, M., Hsin, H. Y., & Ingber, D. E. (2010) · Science · doi:10.1126/science.1188302 · Cited by 4,250 · see citing works

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

Discher, D. E., Mooney, D. J., & Zandstra, P. W. (2009) · Science · doi:10.1126/science.1171643 · Cited by 2,666 · see citing works

A tense situation: forcing tumour progression

Butcher, D. T., Alliston, T. N., & Weaver, V. M. (2009) · Nature reviews. Cancer · doi:10.1038/nrc2544 · Cited by 1,922 · see citing works

The Matrisome: In Silico Definition and In Vivo Characterization by Proteomics of Normal and Tumor Extracellular Matrices

Naba, A., Clauser, K. R., Hoersch, S., Liu, H., Carr, S. A., & Hynes, R. O. (2012) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m111.014647 · Cited by 1,354 · see citing works

Overview of the Matrisome--An Inventory of Extracellular Matrix Constituents and Functions

Hynes, R. O., & Naba, A. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a004903 · Cited by 1,349 · see citing works

Altered regulation of IL-6 production with normal aging. Possible linkage to the age-associated decline in dehydroepiandrosterone and its sulfated derivative

Daynes, R. A., Araneo, B. A., Ershler, W. B., Maloney, C., Li, G. Z., & Ryu, S. Y. (1993) · The Journal of Immunology · doi:10.4049/jimmunol.150.12.5219 · Cited by 1,264 · see citing works

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

Liu, F., Mih, J. D., Shea, B. S., Kho, A. T., Sharif, A. S., Tager, A. M., & Tschumperlin, D. J. (2010) · The Journal of Cell Biology · doi:10.1083/jcb.201004082 · Cited by 799 · see citing works

Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells

Schrader, J., Gordon-Walker, T. T., Aucott, R. L., van Deemter, M., Quaas, A., Walsh, S., Benten, D., Forbes, S. J., Wells, R. G., & Iredale, J. P. (2011) · Hepatology · doi:10.1002/hep.24108 · Cited by 720 · see citing works

Acellular Normal and Fibrotic Human Lung Matrices as a Culture System for <i>In Vitro</i> Investigation

Booth, A. J., Hadley, R., Cornett, A. M., Dreffs, A. A., Matthes, S. A., Tsui, J. L., Weiss, K., Horowitz, J. C., Fiore, V. F., Barker, T. H., et al. (2012) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201204-0754oc · Cited by 665 · see citing works

Marked longevity of human lung parenchymal elastic fibers deduced from prevalence of D-aspartate and nuclear weapons-related radiocarbon.

Shapiro, S. D., Endicott, S. K., Province, M. A., Pierce, J. A., & Campbell, E. J. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115204 · Cited by 645 · see citing works

Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis

Georges, P. C., Hui, J.-J., Gombos, Z., McCormick, M. E., Wang, A. Y., Uemura, M., Mick, R., Janmey, P. A., Furth, E. E., & Wells, R. G. (2007) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00032.2007 · Cited by 577 · see citing works

Fibrotic extracellular matrix activates a profibrotic positive feedback loop

Parker, M. W., Rossi, D., Peterson, M., Smith, K. A., Sikström, K., White, E. S., Connett, J. E., Henke, C. A., Larsson, O. S., & Bitterman, P. B. (2014) · Journal of Clinical Investigation · doi:10.1172/jci71386 · Cited by 554 · see citing works

A Placebo-Controlled, Randomized Trial of Mesenchymal Stem Cells in COPD

Weiss, D. J., Casaburi, R. H., Flannery, R. L., LeRoux, M. A., & Tashkin, D. P. (2013) · CHEST Journal · doi:10.1378/chest.12-2094 · Cited by 424 · see citing works

Human Umbilical Cord Mesenchymal Stem Cells Reduce Fibrosis of Bleomycin-Induced Lung Injury

Moodley, Y., Atienza, D., Manuelpillai, U., Samuel, C. S., Tchongue, J., Ilancheran, S., Boyd, R., & Trounson, A. (2009) · The American Journal of Pathology · doi:10.2353/ajpath.2009.080629 · Cited by 356 · see citing works

Unique Structural Features That Influence Neutrophil Emigration Into the Lung

Burns, A. R., Smith, C. W., & Walker, D. C. (2003) · Physiological Reviews · doi:10.1152/physrev.00023.2002 · Cited by 298 · see citing works

Mesenchymal stem cells enhance recovery and repair following ventilator-induced lung injury in the rat

Curley, G. F., Hayes, M., Ansari, B., Shaw, G., Ryan, A. E., Barry, F., O’Brien, T., O’Toole, D. P., & Laffey, J. G. (2011) · Thorax · doi:10.1136/thoraxjnl-2011-201059 · Cited by 284 · see citing works

Extracellular Matrix Remodeling: The Common Denominator in Connective Tissue Diseases Possibilities for Evaluation and Current Understanding of the Matrix as More Than a Passive Architecture, but a Key Player in Tissue Failure

Karsdal, M. A., Nielsen, M. J., Sand, J. M. B., Henriksen, K., Genovese, F., Bay‐Jensen, A., Smith, V., Adamkewicz, J. I., Christiansen, C., & Leeming, D. J. (2012) · Assay and Drug Development Technologies · doi:10.1089/adt.2012.474 · Cited by 281 · see citing works

Mechanical interactions between collagen and proteoglycans: implications for the stability of lung tissue

Cavalcante, F. S. Á., Ito, S., Brewer, K. K., Sakai, H., Alencar, A. M., de Almeida, M. P., Andrade, J. S., Majumdar, A., Ingenito, E. P., & Suki, B. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00619.2004 · Cited by 262 · see citing works

Matrix Composition and Mechanics of Decellularized Lung Scaffolds

Petersen, T. H., Calle, E. A., Colehour, M. B., & Niklason, L. E. (2011) · Cells Tissues Organs · doi:10.1159/000324896 · Cited by 229 · see citing works

Matrix Stiffness Corresponding to Strictured Bowel Induces a Fibrogenic Response in Human Colonic Fibroblasts

Johnson, L. A., Rodansky, E. S., Sauder, K. L., Horowitz, J. C., Mih, J. D., Tschumperlin, D. J., & Higgins, P. (2013) · Inflammatory Bowel Diseases · doi:10.1097/mib.0b013e3182813297 · Cited by 181 · see citing works

Derivation of Lung Epithelium from Human Cord Blood–derived Mesenchymal Stem Cells

Sueblinvong, V., Loi, R., Eisenhauer, P. L., Bernstein, I. M., Suratt, B. T., Spees, J. L., & Weiss, D. J. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200706-859oc · Cited by 180 · see citing works

Proteoglycan Deposition in Pulmonary Fibrosis

Bensadoun, E., Burke, A. K., Hogg, J. C., & Roberts, C. J. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.154.6.8970376 · Cited by 179 · see citing works

Production and Assessment of Decellularized Pig and Human Lung Scaffolds

Nichols, J. E., Niles, J. A., Riddle, M., Vargas, G., Shilagard, T., Ma, L., Edward, K., Francesca, S. L., Sakamoto, J. H., Vega, S. P., et al. (2013) · Tissue Engineering Part A · doi:10.1089/ten.tea.2012.0250 · Cited by 166 · see citing works

Matrices of Physiologic Stiffness Potently Inactivate Idiopathic Pulmonary Fibrosis Fibroblasts

Marinković, A., Liu, F., & Tschumperlin, D. J. (2012) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2012-0335oc · Cited by 162 · see citing works

The Stumbling Block in Lung Repair of Emphysema: Elastic Fiber Assembly

Shifren, A., & Mecham, R. P. (2006) · Proceedings of the American Thoracic Society · doi:10.1513/pats.200601-009aw · Cited by 161 · see citing works

Clinical grade allogeneic human mesenchymal stem cells restore alveolar fluid clearance in human lungs rejected for transplantation

McAuley, D. F., Curley, G. F., Hamid, U. I., Laffey, J. G., Abbott, J. A., McKenna, D. H., Fang, X., Matthay, M. A., & Lee, J. W. (2014) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00358.2013 · Cited by 152 · see citing works

Extracellular matrix composition in COPD

Annoni, R., Lanças, T., Tanigawa, R. Y., Matsushita, M. D. M., Fernezlian, S., Bruno, A., da Silva, L. F. F., Roughley, P. J., Battaglia, S. L., Dolhnikoff, M., et al. (2012) · European Respiratory Journal · doi:10.1183/09031936.00192611 · Cited by 140 · see citing works

Stimulatory effects of a three-dimensional microenvironment on cell-mediated fibronectin fibrillogenesis

Mao, Y., & Schwarzbauer, J. E. (2005) · Journal of Cell Science · doi:10.1242/jcs.02566 · Cited by 136 · see citing works

Mesenchymal stem cells promote alveolar epithelial cell wound repair in vitro through distinct migratory and paracrine mechanisms

Akram, K. M., Samad, S., Spiteri, M. A., & Forsyth, N. R. (2013) · Respiratory Research · doi:10.1186/1465-9921-14-9 · Cited by 122 · see citing works

Rates of collagen synthesis in lung, skin and muscle obtained in vivo by a simplified method using [3H]proline

Laurent, G. J. (1982) · Biochemical Journal · doi:10.1042/bj2060535 · Cited by 114 · see citing works

Lung-Derived Mesenchymal Stromal Cell Post-Transplantation Survival, Persistence, Paracrine Expression, and Repair of Elastase-Injured Lung

Hoffman, A. M., Paxson, J. A., Mazan, M. R., Davis, A. M., Tyagi, S., Murthy, S., & Ingenito, E. P. (2011) · Stem Cells and Development · doi:10.1089/scd.2011.0105 · Cited by 111 · see citing works

Matrix Rigidity Regulates Cancer Cell Growth by Modulating Cellular Metabolism and Protein Synthesis

Tilghman, R., Blais, E., Cowan, C., Sherman, N., Grigera, P., Jeffery, E. D., Fox, J., Blackman, B., Tschumperlin, D., Papin, J., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037231 · Cited by 72 · see citing works

Biomechanical regulation of mesenchymal cell function

Tschumperlin, D. J., Liu, F., & Tager, A. M. (2012) · Current Opinion in Rheumatology · doi:10.1097/bor.0b013e32835b13cd · Cited by 71 · see citing works

Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases. Comprehensive Review of the Recent Literature 2010–2012

Weiss, D. J. (2013) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201304-090aw · Cited by 62 · see citing works

Effects of the Decellularization Method on the Local Stiffness of Acellular Lungs

Melo, E., Garreta, E., Luque, T., Cortiella, J., Nichols, J. E., Navajas, D., & Farré, R. (2013) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2013.0325 · Cited by 61 · see citing works

Cardiac myofibroblasts differentiated in 3D culture exhibit distinct changes in collagen I production, processing, and matrix deposition

Poobalarahi, F., Baicu, C. F., & Bradshaw, A. D. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00153.2006 · Cited by 61 · see citing works

Aging and lung injury repair: A role for bone marrow derived mesenchymal stem cells

Mora, A. L., & Rojas, M. (2008) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21890 · Cited by 59 · see citing works

Linking Microscopic Spatial Patterns of Tissue Destruction in Emphysema to Macroscopic Decline in Stiffness Using a 3D Computational Model

Parameswaran, H., Majumdar, A., & Suki, B. (2011) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1001125 · Cited by 49 · see citing works

Cell Migration Analyses Within Fibroblast-Derived 3-D Matrices

Cukierman, E. (2004) · Humana Press eBooks · doi:10.1385/1-59259-860-9:079 · Cited by 39 · see citing works

Mechanically and Chemically Tunable Cell Culture System for Studying the Myofibroblast Phenotype

Saums, M. K., Wang, W.-F., Han, B., Madhavan, L., Lin Han, B., Lee, D., & Wells, R. G. (2014) · Langmuir · doi:10.1021/la4047758 · Cited by 32 · see citing works

Therapeutic Potential and Mechanisms of Action of Mesenchymal Stromal Cells for Acute Respiratory Distress Syndrome

Curley, G. F., Scott, J. A., & Laffey, J. G. (2014) · Current Stem Cell Research & Therapy · doi:10.2174/1574888x09666140228144812 · Cited by 27 · see citing works

The effects of proteolytic enzymes on the tensile strength of human lung.

Senior, R. M., Bielefeld, D. R., & Mk, A. (1975) · PubMed · doi:10.1164/arrd.1975.111.2.184 · Cited by 25 · see citing works

Stress-strain analysis and the lung.

RODARTE, J. R. (1982) · PubMed · Cited by 11 · see citing works

The instructive extracellular matrix of the lung: basic composition and alterations in chronic lung disease

Burgstaller, G., Oehrle, B., Gerckens, M., White, E. S., Schiller, H. B., & Eickelberg, O. (2017) · European Respiratory Journal · doi:10.1183/13993003.01805-2016 · Cited by 483 · see citing works

Fractional viscoelastic models for power-law materials

Bonfanti, A., Kaplan, J., Charras, G., & Kabla, A. (2020) · Soft Matter · doi:10.1039/d0sm00354a · Cited by 467 · see citing works

Aging and Lung Disease

Cho, S. J., & Stout-Delgado, H. W. (2020) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021119-034610 · Cited by 458 · see citing works

The big five in fibrosis: Macrophages, myofibroblasts, matrix, mechanics, and miscommunication

Pakshir, P., & Hinz, B. (2018) · Matrix Biology · doi:10.1016/j.matbio.2018.01.019 · Cited by 396 · see citing works

Print Me An Organ! Why We Are Not There Yet

Ng, W. L., Chua, C. K., & Shen, Y. (2019) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2019.101145 · Cited by 292 · see citing works

The extracellular matrix – the under‐recognized element in lung disease?

Burgess, J. K., Mauad, T., Tjin, G., Karlsson, J., & Westergren‐Thorsson, G. (2016) · The Journal of Pathology · doi:10.1002/path.4808 · Cited by 263 · see citing works

Biophysical Regulation of Cell Behavior—Cross Talk between Substrate Stiffness and Nanotopography

Yang, Y. S., Wang, K., Gu, X., & Leong, K. W. (2017) · Engineering · doi:10.1016/j.eng.2017.01.014 · Cited by 264 · see citing works

Fibroblasts in the Tumor Microenvironment: Shield or Spear?

Alkasalias, T., Moyano‐Galceran, L., Arsenian‐Henriksson, M., & Lehti, K. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19051532 · Cited by 243 · see citing works

Recent advances in chronic obstructive pulmonary disease pathogenesis: from disease mechanisms to precision medicine

Brandsma, C., van den Berge, M., Hackett, T., Brusselle, G., & Timens, W. (2019) · The Journal of Pathology · doi:10.1002/path.5364 · Cited by 204 · see citing works

Therapeutic approaches to control tissue repair and fibrosis: Extracellular matrix as a game changer

Walraven, M., & Hinz, B. (2018) · Matrix Biology · doi:10.1016/j.matbio.2018.02.020 · Cited by 194 · see citing works

In Vitro Models to Study Human Lung Development, Disease and Homeostasis.

Miller, A. J., & Spence, J. (2017) · Physiology · doi:10.1152/physiol.00041.2016 · Cited by 166 · see citing works

Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis

Jones, M. G., Andriotis, O. G., Roberts, J., Lunn, K., Tear, V. J., Cao, L., Ask, K., Smart, D. E., Bonfanti, A., Johnson, P., et al. (2018) · eLife · doi:10.7554/elife.36354 · Cited by 162 · see citing works

Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection

Edwards, C. E., Yount, B. L., Graham, R. L., Leist, S. R., Hou, Y. J., Dinnon, K. H., Sims, A. M., Swanstrom, J., Gully, K. L., Scobey, T., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2001046117 · Cited by 159 · see citing works

Raman Spectroscopy: Guiding Light for the Extracellular Matrix

Bergholt, M. S., Serio, A., & Albro, M. B. (2019) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00303 · Cited by 143 · see citing works

Human organoids-on-chips for biomedical research and applications

Wang, H., Ning, X., Zhao, F. H., Zhao, H., & Li, D. (2024) · Theranostics · doi:10.7150/thno.90492 · Cited by 138 · see citing works

A Systematic Review of the Role of Dysfunctional Wound Healing in the Pathogenesis and Treatment of Idiopathic Pulmonary Fibrosis

Betensley, A. D., Sharif, R., & Karamichos, D. (2016) · Journal of Clinical Medicine · doi:10.3390/jcm6010002 · Cited by 121 · see citing works

Photo-Uncaging of a Microtubule-Targeted Rigidin Analogue in Hypoxic Cancer Cells and in a Xenograft Mouse Model

van Rixel, V. H. S., Ramu, V., Auyeung, A. B., Beztsinna, N., Leger, D. Y., Lameijer, L. N., Hilt, S. T., Dévédec, S. E. L., Yıldız, T., Betancourt, T., et al. (2019) · Journal of the American Chemical Society · doi:10.1021/jacs.9b07225 · Cited by 120 · see citing works

Strategies to capitalize on cell spheroid therapeutic potential for tissue repair and disease modeling

Griffin, K. H., Fok, S. W., & Leach, J. K. (2022) · npj Regenerative Medicine · doi:10.1038/s41536-022-00266-z · Cited by 132 · see citing works

Matrix stiffness and tumor-associated macrophages modulate epithelial to mesenchymal transition of human adenocarcinoma cells

Alonso‐Nocelo, M., Raimondo, T. M., Vining, K. H., López‐López, R., de la Fuente, M., & Mooney, D. J. (2018) · Biofabrication · doi:10.1088/1758-5090/aaafbc · Cited by 116 · see citing works

Decellularized scaffolds in regenerative medicine

Yu, Y., Alkhawaji, A., Ding, Y., & Mei, J. (2016) · Oncotarget · doi:10.18632/oncotarget.10945 · Cited by 113 · see citing works

Airway-On-A-Chip: Designs and Applications for Lung Repair and Disease

Bennet, T. J., Randhawa, A., Hua, J., & Cheung, K. C. (2021) · Cells · doi:10.3390/cells10071602 · Cited by 99 · see citing works

Targeted inhibition of PI3 kinase/mTOR specifically in fibrotic lung fibroblasts suppresses pulmonary fibrosis in experimental models

Hettiarachchi, S. U., Li, Y., Roy, J., Zhang, F., Puchulu‐Campanella, E., Lindeman, S. D., Srinivasarao, M., Tsoyi, K., Liang, X., Ayaub, E. A., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aay3724 · Cited by 94 · see citing works

Cellular Senescence in the Lung: The Central Role of Senescent Epithelial Cells

Hansel, C., Jendrossek, V., & Klein, D. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21093279 · Cited by 85 · see citing works

Extracellular matrix remodelling in COPD

Karakioulaki, M., Papakonstantinou, E., & Stolz, D. (2020) · European Respiratory Review · doi:10.1183/16000617.0124-2019 · Cited by 83 · see citing works

Environmental Exposures and Lung Aging: Molecular Mechanisms and Implications for Improving Respiratory Health

Eckhardt, C. M., & Wu, H. (2021) · Current Environmental Health Reports · doi:10.1007/s40572-021-00328-2 · Cited by 82 · see citing works

Extracellular Matrix Stiffness: Mechanotransduction and Mechanobiological Response-Driven Strategies for Biomedical Applications Targeting Fibroblast Inflammation

Tiskratok, W., Chuinsiri, N., Limraksasin, P., Kyawsoewin, M., & Jitprasertwong, P. (2025) · Polymers · doi:10.3390/polym17060822 · Cited by 88 · see citing works

TGF‐β‐induced profibrotic signaling is regulated in part by the WNT receptor Frizzled‐8

Spanjer, A. I. R., Baarsma, H. A., Oostenbrink, L. M., Jansen, S. R., Kuipers, C. C., Lindner, M., Postma, D. S., Meurs, H., Heijink, I. H., Gosens, R., et al. (2016) · The FASEB Journal · doi:10.1096/fj.201500129 · Cited by 79 · see citing works

Identification of a pro-angiogenic functional role for FSP1-positive fibroblast subtype in wound healing

Saraswati, S., Marrow, S. M., Watch, L. A., & Young, P. P. (2019) · Nature Communications · doi:10.1038/s41467-019-10965-9 · Cited by 79 · see citing works

Inhibition of ROCK ameliorates pulmonary fibrosis by suppressing M2 macrophage polarisation through phosphorylation of STAT3

Li, Q., Cheng, Y., Zhang, Z., Bi, Z., Ma, X., Wei, Y., & Wei, X. (2022) · Clinical and Translational Medicine · doi:10.1002/ctm2.1036 · Cited by 77 · see citing works

Pulmonary Stretch and Lung Mechanotransduction: Implications for Progression in the Fibrotic Lung

Marchioni, A., Tonelli, R., Cerri, S., Castaniere, I., Andrisani, D., Gozzi, F., Bruzzi, G., Manicardi, L., Moretti, A., Demurtas, J., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126443 · Cited by 75 · see citing works

Host Recovery from Respiratory Viral Infection

Wei, X., Narasimhan, H., Zhu, B., & Sun, J. (2023) · Annual Review of Immunology · doi:10.1146/annurev-immunol-101921-040450 · Cited by 61 · see citing works

Adhesion strength and contractility enable metastatic cells to become adurotactic

Yeoman, B., Shatkin, G., Beri, P., Banisadr, A., Katira, P., & Engler, A. (2020) · Cell Reports · doi:10.1016/j.celrep.2021.108816 · Cited by 52 · see citing works

Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis

Hofmann, K., Fiedler, S., Vierkotten, S., Weber, J., Klee, S., Jia, J., Zwickenpflug, W., Flockerzi, V., Storch, U., Yildirim, A. Ö., et al. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2016.12.002 · Cited by 60 · see citing works

Moderate hyperoxia induces senescence in developing human lung fibroblasts

You, K., Parikh, P., Khandalavala, K., Wicher, S. A., Manlove, L. J., Yang, B., Roesler, A., Roos, B. B., Teske, J. J., Britt, R. D., et al. (2019) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00067.2019 · Cited by 60 · see citing works

Diagnostic role of circulating extracellular matrix-related proteins in non-small cell lung cancer

Andriani, F., Landoni, E., Mensah, M., Facchinetti, F., Miceli, R., Tagliabue, E., Giussani, M., Callari, M., Cecco, L. D., Colombo, M. P., et al. (2018) · BMC Cancer · doi:10.1186/s12885-018-4772-0 · Cited by 57 · see citing works

Cancer‐associated fibroblast migration in non‐small cell lung cancers is modulated by increased integrin α11 expression

Iwai, M., Tulafu, M., Togo, S., Kawaji, H., Kadoya, K., Namba, Y., Jin, J., Watanabe, J. A., Okabe, T., Hidayat, M., et al. (2021) · Molecular Oncology · doi:10.1002/1878-0261.12937 · Cited by 54 · see citing works

Staphylococcus aureus Arsenal To Conquer the Lower Respiratory Tract

Pivard, M., Moreau, K., & Vandenesch, F. (2021) · mSphere · doi:10.1128/msphere.00059-21 · Cited by 53 · see citing works

The bio-distribution, clearance pathways, and toxicity mechanisms of ambient ultrafine particles

Han, D., Chen, R., Kan, H., & Xu, Y. (2023) · Eco-Environment & Health · doi:10.1016/j.eehl.2023.06.001 · Cited by 52 · see citing works

Matrix remodeling in chronic lung diseases

Gu, B., Madison, M. C., Corry, D. B., & Kheradmand, F. (2018) · Matrix Biology · doi:10.1016/j.matbio.2018.03.012 · Cited by 50 · see citing works

The critical role of collagen VI in lung development and chronic lung disease

Mereness, J. A., & Mariani, T. J. (2021) · Matrix Biology Plus · doi:10.1016/j.mbplus.2021.100058 · Cited by 45 · see citing works

Comparison of cytotoxicity of IQOS aerosols to smoke from Marlboro Red and 3R4F reference cigarettes

Davis, B. A., To, V., & Talbot, P. (2019) · Toxicology in Vitro · doi:10.1016/j.tiv.2019.104652 · Cited by 44 · see citing works

Curcumin inhibits paraquat induced lung inflammation and fibrosis by extracellular matrix modifications in mouse model

Tyagi, N., Dash, D., & Singh, R. (2016) · Inflammopharmacology · doi:10.1007/s10787-016-0286-z · Cited by 43 · see citing works

3D in vitro hydrogel models to study the human lung extracellular matrix and fibroblast function

Phogat, S., Thiam, F., Yazeedi, S. A., Abokor, F. A., & Osei, E. T. (2023) · Respiratory Research · doi:10.1186/s12931-023-02548-6 · Cited by 45 · see citing works

ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation

Jones, D. L., Meridew, J., Link, P., Ducharme, M. T., Lydon, K. L., Choi, K. M., Caporarello, N., Tan, Q., Espinosa, A. M. D., Xiong, Y.-N., et al. (2021) · Journal of Cell Biology · doi:10.1083/jcb.202007152 · Cited by 31 · see citing works

Modeling Extracellular Matrix-Cell Interactions in Lung Repair and Chronic Disease

Hackett, T., & Osei, E. T. (2021) · Cells · doi:10.3390/cells10082145 · Cited by 41 · see citing works

Biomaterial inks and bioinks for fabricating 3D biomimetic lung tissue: A delicate balancing act between biocompatibility and mechanical printability

Karamchand, L., Makeiff, D., Gao, Y., Azyat, K., Serpe, M. J., & Kulka, M. (2022) · Bioprinting · doi:10.1016/j.bprint.2022.e00255 · Cited by 43 · see citing works

Targeting progranulin alleviated silica particles-induced pulmonary inflammation and fibrosis via decreasing Il-6 and Tgf-β1/Smad

Zhao, M., Wang, M., Chen, X., Gao, Y., Chen, Q., Wang, L., Bao, Q., Sun, D., Du, W., Xu, Y., et al. (2023) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2023.133199 · Cited by 38 · see citing works

Fibroblast–matrix interplay: Nintedanib and pirfenidone modulate the effect of IPF fibroblast‐conditioned matrix on normal fibroblast phenotype

Shochet, G. E., Wollin, L., & Shitrit, D. (2018) · Respirology · doi:10.1111/resp.13287 · Cited by 38 · see citing works

Material Strategies for Modulating Epithelial to Mesenchymal Transitions

Mihalko, E. P., & Brown, A. C. (2017) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.6b00751 · Cited by 37 · see citing works

Acute exposure of mice to hydrochloric acid leads to the development of chronic lung injury and pulmonary fibrosis

Marinova, M. D., Solopov, P. A., Dimitropoulou, C., Biancatelli, R. M. L. C., & Catravas, J. D. (2019) · Inhalation Toxicology · doi:10.1080/08958378.2019.1624895 · Cited by 37 · see citing works

Pseudomonas aeruginosa uses multiple receptors for adherence to laminin during infection of the respiratory tract and skin wounds

Paulsson, M., Su, Y., Ringwood, T., Uddén, F., & Riesbeck, K. (2019) · Scientific Reports · doi:10.1038/s41598-019-54622-z · Cited by 37 · see citing works

Implications for Extracellular Matrix Interactions With Human Lung Basal Stem Cells in Lung Development, Disease, and Airway Modeling

Busch, S. M., Lorenzana, Z., & Ryan, A. L. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.645858 · Cited by 37 · see citing works

Mechanobiology of Pulmonary Diseases: A Review of Engineering Tools to Understand Lung Mechanotransduction

Novak, C. M., Ballinger, M. N., & Ghadiali, S. N. (2021) · Journal of Biomechanical Engineering · doi:10.1115/1.4051118 · Cited by 39 · see citing works

Multi-scale models of lung fibrosis

Leonard‐Duke, J., Evans, S., Hannan, R. T., Barker, T. H., Bates, J. H. T., Bonham, C. A., Moore, B. B., Kirschner, D. E., & Peirce, S. M. (2020) · Matrix Biology · doi:10.1016/j.matbio.2020.04.003 · Cited by 36 · see citing works

Unfolded Protein Response Inhibition Reduces Middle East Respiratory Syndrome Coronavirus-Induced Acute Lung Injury

Sims, A. M., Mitchell, H. D., Gralinski, L. E., Kyle, J. E., Burnum-Johnson, K., Lam, M., Fulcher, M. L., West, A., Smith, R. D., Randell, S. H., et al. (2021) · mBio · doi:10.1128/mbio.01572-21 · Cited by 36 · see citing works

Exposure Effects Beyond the Epithelial Barrier: Transepithelial Induction of Oxidative Stress by Diesel Exhaust Particulates in Lung Fibroblasts in an Organotypic Human Airway Model

Faber, S. C., McNabb, N. A., Ariel, P., Aungst, E. R., & McCullough, S. D. (2020) · Toxicological Sciences · doi:10.1093/toxsci/kfaa085 · Cited by 35 · see citing works

Alveolar epithelial cells and microenvironmental stiffness synergistically drive fibroblast activation in three-dimensional hydrogel lung models

Caracena, T., Blomberg, R., Hewawasam, R. S., Fry, Z. E., Riches, D. W. H., & Magin, C. M. (2022) · Biomaterials Science · doi:10.1039/d2bm00827k · Cited by 35 · see citing works

Effects of mechanical ventilation on the interstitial extracellular matrix in healthy lungs and lungs affected by acute respiratory distress syndrome: a narrative review

Al-Husinat, L., Azzam, S., Sharie, S. A., Sharie, A. H. A., Battaglini, D., Robba, C., Marini, J. J., Thornton, L. T., Cruz, F. F., Silva, P. L., et al. (2024) · Critical Care · doi:10.1186/s13054-024-04942-y · Cited by 36 · see citing works

TGF-β1-induced deposition of provisional extracellular matrix by tracheal basal cells promotes epithelial-to-mesenchymal transition in a c-Jun NH2-terminal kinase-1-dependent manner

van der Velden, J. L. J., Wagner, D. E., Lahue, K. G., Abdalla, S. T., Lam, Y., Weiss, D. J., & Janssen-Heininger, Y. M. W. (2018) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00053.2017 · Cited by 33 · see citing works

Dietary ω-6 polyunsaturated fatty acid arachidonic acid increases inflammation, but inhibits ECM protein expression in COPD

Rutting, S., Papanicolaou, M., Xenaki, D., Wood, L. G., Mullin, A. M., Hansbro, P. M., & Oliver, B. G. G. (2018) · Respiratory Research · doi:10.1186/s12931-018-0919-4 · Cited by 33 · see citing works

The Role of miRNAs in Extracellular Matrix Repair and Chronic Fibrotic Lung Diseases

Usman, K., Hsieh, A., & Hackett, T. (2021) · Cells · doi:10.3390/cells10071706 · Cited by 33 · see citing works

Extracellular Vesicles and Alveolar Epithelial-Capillary Barrier Disruption in Acute Respiratory Distress Syndrome: Pathophysiological Role and Therapeutic Potential

Esquivel‐Ruiz, S., González‐Rodríguez, P., Lorente, J. A., Pérez‐Vizcaíno, F., Herrero, R., & Moreno, L. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.752287 · Cited by 32 · see citing works

A glitch in the matrix: Age‐dependent changes in the extracellular matrix facilitate common sites of metastasis

Marino, G. E., & Weeraratna, A. T. (2020) · Aging and Cancer · doi:10.1002/aac2.12013 · Cited by 29 · see citing works

Baseline Stiffness Modulates the Non-Linear Response to Stretch of the Extracellular Matrix in Pulmonary Fibrosis

Júnior, C., Narciso, M., Marhuenda, E., Almendros, I., Farré, R., Navajas, D., Otero, J., & Gavara, N. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222312928 · Cited by 29 · see citing works

How bacteria hack the matrix and dodge the bullets of immunity

Paulsson, M., & Riesbeck, K. (2018) · European Respiratory Review · doi:10.1183/16000617.0018-2018 · Cited by 28 · see citing works

Extracellular matrix remodeling associated with bleomycin-induced lung injury supports pericyte-to-myofibroblast transition

Hannan, R. T., Miller, A. E., Hung, R.-C., Sano, C., Peirce, S. M., & Barker, T. H. (2020) · Matrix Biology Plus · doi:10.1016/j.mbplus.2020.100056 · Cited by 28 · see citing works

Epithelial–stromal cell interactions and extracellular matrix mechanics drive the formation of airway-mimetic tubular morphology in lung organoids

Güney, T. G., Herranz, A. M., Mumby, S. E., Dunlop, I. E., & Adcock, I. M. (2021) · iScience · doi:10.1016/j.isci.2021.103061 · Cited by 28 · see citing works

Substrate Stiffness-Dependent Carbon Nanotube-Induced Lung Fibrogenesis

Wang, K., Shi, L., Linthicum, W., Man, K., He, X., Wen, Q., Rojanasakul, L. W., Rojanasakul, Y., & Yang, Y. S. (2019) · Nano Letters · doi:10.1021/acs.nanolett.9b01943 · Cited by 27 · see citing works

Collagen VI Deficiency Results in Structural Abnormalities in the Mouse Lung

Mereness, J. A., Bhattacharya, S., Ren, Y., Wang, Q., Anderson, C., Donlon, K., Dylag, A. M., Haak, J., Angelin, A., Bonaldo, P., et al. (2019) · American Journal Of Pathology · doi:10.1016/j.ajpath.2019.10.014 · Cited by 27 · see citing works

Effect of Hyaluronic Acid on the Differentiation of Mesenchymal Stem Cells into Mature Type II Pneumocytes

Sala, F. D., di Gennaro, M., Lista, G., Messina, F., Ambrosio, L., & Borzacchiello, A. (2021) · Polymers · doi:10.3390/polym13172928 · Cited by 27 · see citing works

Dietary omega-6, but not omega-3, polyunsaturated or saturated fatty acids increase inflammation in primary lung mesenchymal cells

Rutting, S., Xenaki, D., Lau, E., Horvat, J. C., Wood, L. G., Hansbro, P. M., & Oliver, B. G. G. (2018) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00438.2017 · Cited by 27 · see citing works

3D cell culture models in research: applications to lung cancer pharmacology

Vella, N., Fenech, A. G., & Magri, V. P. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1438067 · Cited by 26 · see citing works

The combination of ultrafine carbon black and lead provokes cytotoxicity and apoptosis in mice lung fibroblasts through oxidative stress-activated mitochondrial pathways

Chu, S., Li, X., Sun, N., He, F., Cui, Z., Li, Y., & Liu, R. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.149420 · Cited by 26 · see citing works

SRC and TKS5 mediated podosome formation in fibroblasts promotes extracellular matrix invasion and pulmonary fibrosis

Barbayianni, I., Kanellopoulou, P., Fanidis, D., Nastos, D., Ntouskou, E.-D., Galaris, A., Harokopos, V., Hatzis, P., Tsitoura, E., Homer, R., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-41614-x · Cited by 24 · see citing works

Respiratory defects in the CrtapKO mouse model of osteogenesis imperfecta

Dimori, M., Heard‐Lipsmeyer, M. E., Byrum, S. D., Mackintosh, S. G., Kurten, R. C., Carroll, J. L., & Morello, R. (2020) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00313.2019 · Cited by 25 · see citing works

Liquid application dosing alters the physiology of air-liquid interface (ALI) primary human bronchial epithelial cell/lung fibroblast co-cultures and in vitro testing relevant endpoints

Mallek, N. M., Martin, E. M., Dailey, L. A., & McCullough, S. D. (2024) · Frontiers in Toxicology · doi:10.3389/ftox.2023.1264331 · Cited by 27 · see citing works

Transurethral incision of the prostate: a viable alternative to transurethral resection.

Kletscher, B. A., & Oesterling, J. E. (1992) · PubMed · Cited by 25 · see citing works

Glycogen drives tumour initiation and progression in lung adenocarcinoma

Clarke, H. A., Hawkinson, T. R., Shedlock, C. J., Medina, T., Ribas, R. A., Wu, L., Liu, Z., Ma, X., Xia, Y., Huang, Y., et al. (2025) · Nature Metabolism · doi:10.1038/s42255-025-01243-8 · Cited by 23 · see citing works

Engineered Three-Dimensional Tumor Models to Study Natural Killer Cell Suppression

Temples, M. N., Adjei, I. M., Nimocks, P. M., Djeu, J. Y., & Sharma, B. (2020) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.0c00259 · Cited by 24 · see citing works

Role of metalloproteinases and TNF-α in obesity-associated asthma in mice

Vieira, C. P., de Oliveira, L. P., da Silva, M. B., André, D. M., Tavares, E. B. G., Pimentel, E. R., & Antunes, E. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.118191 · Cited by 23 · see citing works

Small airway fibroblasts from patients with chronic obstructive pulmonary disease exhibit cellular senescence

Wrench, C., Baker, J. R., Monkley, S., Fenwick, P. S., Murray, L. A., Donnelly, L., & Barnes, P. J. (2023) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00419.2022 · Cited by 23 · see citing works

Role of epigenetics in the regulation of skin aging and geroprotective intervention: A new sight

Pozzo, L. D., Xu, Z., Lin, S., Wang, J., Wang, Y., Enechojo, O. S., Abankwah, J. K., Peng, Y., Chu, X., Zhou, H., et al. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116592 · Cited by 22 · see citing works

Mechanical stretch and LPS affect the proliferation, extracellular matrix remodeling and viscoelasticity of lung fibroblasts

Xie, Y., Qian, Y., Wang, Y., Liu, K., & Li, X. (2020) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2020.9133 · Cited by 22 · see citing works

NR2F2 alleviates pulmonary fibrosis by inhibition of epithelial cell senescence

Wan, R., Long, S., Ma, S., Yan, P., Li, Z., Xu, K., Lian, H., Li, W., Duan, Y., Zhu, M., et al. (2024) · Respiratory Research · doi:10.1186/s12931-024-02777-3 · Cited by 21 · see citing works

Mechanosensitive Channels in Lung Health and Disease

Migulina, N., Kelley, B., Zhang, E. Y., Pabelick, C. M., Prakash, Y. S., & Vogel, E. R. (2023) · Comprehensive physiology · doi:10.1002/j.2040-4603.2023.tb00284.x · Cited by 21 · see citing works

Development of chronic lung injury and pulmonary fibrosis in mice following acute exposure to nitrogen mustard

Solopov, P. A., Marinova, M. D., Dimitropoulou, C., Biancatelli, R. M. L. C., & Catravas, J. D. (2020) · Inhalation Toxicology · doi:10.1080/08958378.2020.1757791 · Cited by 21 · see citing works

Influence of Extracellular Vesicles on Lung Stromal Cells during Breast Cancer Metastasis

Patel, U., Susman, D., & Allan, A. L. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241411801 · Cited by 20 · see citing works

Cortex Mori Radicis[Morus Alba L. (Moraceae)] extract alleviates senescence via PI3K/Akt signaling in COPD fibroblasts

Zeng, X., Gao, D.-D., & Zhang, F. (2024) · Phytomedicine · doi:10.1016/j.phymed.2024.156004 · Cited by 19 · see citing works

Decellularized organ biomatrices facilitate quantifiable in vitro 3D cancer metastasis models

VandenHeuvel, S. N., Farris, H. A., Noltensmeyer, D. A., Roy, S., Donehoo, D. A., Kopetz, S., Haricharan, S., Walsh, A. J., & Raghavan, S. A. (2022) · Soft Matter · doi:10.1039/d1sm01796a · Cited by 19 · see citing works

Properties of Adult Lung Stem and Progenitor Cells

Bertoncello, I. (2016) · Journal of Cellular Physiology · doi:10.1002/jcp.25404 · Cited by 18 · see citing works

Stiffness Mediated‐Mechanosensation of Airway Smooth Muscle Cells on Linear Stiffness Gradient Hydrogels

Tan, Y. H., Wang, K. C. W., Chin, I. L., Sanderson, R. W., Li, J., Kennedy, B. F., Noble, P. B., & Choi, Y. S. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202304254 · Cited by 18 · see citing works

Magnetic microboats for floating, stiffness tunable, air–liquid interface epithelial cultures

Chandrasekaran, A., Kouthouridis, S., Lee, W., Lin, N., Ma, Z., Turner, M. J., Hanrahan, J. W., & Moraes, C. (2019) · Lab on a Chip · doi:10.1039/c9lc00267g · Cited by 18 · see citing works

Impact of stress, immunity, and signals from endocrine and nervous system on fascia

Barsotti, N., Chiera, M., Lanaro, D., & Fioranelli, M. (2020) · Frontiers in Bioscience-Elite · doi:10.2741/870 · Cited by 18 · see citing works

A chronic Acinetobacter baumannii pneumonia model to study long-term virulence factors, antibiotic treatments, and polymicrobial infections

Jackson-Litteken, C. D., Venanzio, G. D., Janet-Maitre, M., Castro, Í. A., Mackel, J. J., Wilson, L. D., Rosen, D. A., López, C. B., & Feldman, M. F. (2025) · Nature Communications · doi:10.1038/s41467-025-62655-4 · Cited by 24 · see citing works

Asthmatic Eosinophils Promote Contractility and Migration of Airway Smooth Muscle Cells and Pulmonary Fibroblasts In Vitro

Janulaitytė, I., Januškevičius, A., Kalinauskaitė-Žukauskė, V., Palačionytė, J., & Malakauskas, K. (2021) · Cells · doi:10.3390/cells10061389 · Cited by 19 · see citing works

Cub domain-containing protein 1 negatively regulates TGF-β signaling and myofibroblast differentiation

Noskovičová, N., Heinzelmann, K., Burgstaller, G., Behr, J., & Eickelberg, O. (2018) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00205.2017 · Cited by 17 · see citing works

Age-related lung tissue remodeling due to the local distribution of MMP-2, TIMP-2, TGF-β and Hsp70

Vitenberga-Verza, Z., & Pilmane, M. (2018) · Biotechnic & Histochemistry · doi:10.1080/10520295.2017.1421322 · Cited by 16 · see citing works

Multiscale computational model predicts how environmental changes and treatments affect microvascular remodeling in fibrotic disease

Leonard‐Duke, J., Agro, S. M. J., Csordas, D. J., Bruce, A. C., Eggertsen, T. G., Tavakol, T. N., Comlekoglu, T., Barker, T. H., Bonham, C. A., Saucerman, J. J., et al. (2024) · PNAS Nexus · doi:10.1093/pnasnexus/pgae551 · Cited by 18 · see citing works

Compositional changes of the lung extracellular matrix in acute respiratory distress syndrome

Fan, Y., Moser, J., Jongman, R. M., Borghuis, T., Vonk, J. M., Timens, W., van Meurs, M., Pillay, J., & Burgess, J. K. (2025) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.01007.2024 · Cited by 16 · see citing works

Identification of a fibronectin-binding protein signature associated with idiopathic pulmonary fibrosis

Sun, Y., King, B., Hamlin, A. J., Saniepay, M., Gorshkov, K., Barker, G. A., Ziegler, M., Mukundan, S., Cvijic, M. E., & Schwarzbauer, J. E. (2024) · Cells and Development · doi:10.1016/j.cdev.2024.203941 · Cited by 15 · see citing works

Extracellular Matrix Stiffness in Lung Health and Disease

Guo, T., He, C., Venado, A. E., & Zhou, Y. (2022) · Comprehensive physiology · doi:10.1002/j.2040-4603.2022.tb00222.x · Cited by 48 · see citing works

Dynamic Reciprocity: The Role of the Extracellular Matrix Microenvironment in Amplifying and Sustaining Pathological Lung Fibrosis

Burgess, J. K., Muizer, K., Brandsma, C., & Heijink, I. H. (2018) · Molecular and translational medicine · doi:10.1007/978-3-319-98143-7_9 · Cited by 4 · see citing works

The extracellular matrix and mechanotransduction in pulmonary fibrosis

Deng, Z., Fear, M. W., Choi, Y. S., Wood, F. M., Allahham, A., Mutsaers, S. E., & Prêle, C. M. (2020) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2020.105802 · Cited by 122 · see citing works

Chronic lung diseases: entangled in extracellular matrix

Burgess, J. K., & Harmsen, M. C. (2022) · European Respiratory Review · doi:10.1183/16000617.0202-2021 · Cited by 65 · see citing works

Matrix, Mesenchyme, and Mechanotransduction

Tschumperlin, D. J. (2015) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201407-320mg · Cited by 65 · see citing works