The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Factors Affecting Intestinal Absorption of Highly Lipophilic Food Microconstituents (Fat-Soluble Vitamins, Carotenoids and Phytosterols)
Abstract
Highly lipophilic food microconstituents (HLFMs) with octanol-water partition coefficients log10 P(c) > 8 include the fat-soluble vitamins (A, E, D and K) and phytochemicals with potential health benefits, the carotenoids and phytosterols. It has been assumed that these compounds have the same metabolism in the human upper gastrointestinal tract and that they follow the same fate as lipids. However, a literature review shows that the metabolism of HLFMs in the upper gastrointestinal tract depends on each HLFM species. For example, some HLFM esters are hydrolyzed mainly by pancreatic lipase, others by bile salt-stimulated lipase; some HLFMs are apparently absorbed by passive diffusion, others by a transporter. Also, although some factors (HLFM molecular species, fat, food matrix) affect absorption efficiency of most HLFMs, other factors (fibers, microconstituents) apparently affect absorption only of some HLFMs. The mnemonic acronym SLAMENGHI, previously proposed to list the factors affecting the bioavailability of carotenoids, was used here to review current knowledge of the factors suspected to affect the intestinal absorption of HLFMs. The available data reveal numerous gaps in the knowledge of the metabolism of HLFMs and the factors that affect their absorption. These gaps need to be filled to be able to formulate HLFMs so as to promote greater absorption efficiency.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Determination of Phylloquinone and Menaquinones in Food
Schurgers, L. J., & Vermeer, C. (2000) · Pathophysiology of Haemostasis and Thrombosis · doi:10.1159/000054147 · Cited by 397
A class B scavenger receptor mediates the cellular uptake of carotenoids in Drosophila
Kiefer, C., Sumser, E., Wernet, M. F., & von Lintig, J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.162182899 · Cited by 255
Ben-Amotz, A., & Levy, Y. (1996) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/63.5.729 · Cited by 142
Weng, W., Li, L., van Bennekum, A. M., Potter, S. H., Harrison, E. H., Blaner, W. S., Breslow, J. L., & Fisher, E. A. (1999) · Biochemistry · doi:10.1021/bi981679a · Cited by 135
Cited by
Berger, M. M., Shenkin, A., Schweinlin, A., Amrein, K., Augsburger, M., Biesalski, H.-K., Bischoff, S. C., Casaer, M. P., Gundogan, K., Lepp, H.-L., et al. (2022) · Clinical Nutrition · doi:10.1016/j.clnu.2022.02.015 · Cited by 615
Bioaccessibility of Carotenoids and Vitamin E from Their Main Dietary Sources
Reboul, E., Richelle, M., Perrot, E., Desmoulins-Malezet, C., Pirisi, V., & Borel, P. (2006) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf061818s · Cited by 444
Self-citationBorel, P., Lietz, G., Goncalves, A., Szabo de Edelenyi, F., Lecompte, S., Curtis, P., Goumidi, L., Caslake, M. J., Miles, E. A., Packard, C., et al. (2013) · The Journal of Nutrition · doi:10.3945/jn.112.172734 · Cited by 156
Self-citationBohn, T., Desmarchelier, C., El, S. N., Keijer, J., van Schothorst, E., Rühl, R., & Borel, P. (2019) · Proceedings of the Nutrition Society · doi:10.1017/s0029665118002641 · Cited by 156
Self-citationAlbers, R., Bourdet-Sicard, R., Braun, D., Calder, P. C., Herz, U., Lambert, C., Lenoir-Wijnkoop, I., Méheust, A., Ouwehand, A., Phothirath, P., et al. (2013) · British Journal of Nutrition · doi:10.1017/s0007114513001505 · Cited by 150
Metadata
- Authors
- Borel, P.
- Venue
- Clinical Chemistry and Laboratory Medicine
- Publisher
- Walter de Gruyter GmbH
- Published
- 2003-01-07
- Volume
- 41
- Issue
- 8
- Pages
- 979-94
- ISSN
- 1434-6621 (ISSN-L)
- OpenAlex
- W2066601307
- Cited by
- 241
- References
- 4
- FWCI
- 5.07
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Factors Affecting Intestinal Absorption of Highly Lipophilic Food Microconstituents (Fat-Soluble Vitamins, Carotenoids and Phytosterols). https://app.cochat.ai/papers/10.1515/cclm.2003.151
- The paper
- Borel, P. (2003). Factors Affecting Intestinal Absorption of Highly Lipophilic Food Microconstituents (Fat-Soluble Vitamins, Carotenoids and Phytosterols). Clinical Chemistry and Laboratory Medicine. https://doi.org/10.1515/cclm.2003.151
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
