CoChat
Sign Up
Cited by 209

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Antimicrobial properties of porphyrins

Stojiljkovic, Igor, Evavold, Brian D, Kumar, Veena·2001·Expert Opinion on Investigational Drugs
DOI 10.1517/13543784.10.2.309
Open this paper in CoChat — free account

Abstract

A large number of natural and synthetic porphyrins of diverse chemical compositions and characteristics can be isolated from nature or synthesised in the laboratory. Antimicrobial and antiviral activities of porphyrins are based on their ability to catalyse peroxidase and oxidase reactions, absorb photons and generate reactive oxygen species (ROS) and partition into lipids of bacterial membranes. Light-dependent, photodynamic activity of natural and synthetic porphyrins and pthalocyanines against Gram-positive and Gram-negative bacteria has been well demonstrated. Some non-iron metalloporphyrins (MPs) possess a powerful light-independent antimicrobial activity that is based on the ability of these compounds to increase the sensitivity of bacteria to ROS or directly produce ROS. MPs mimic haem in their molecular structure and are actively accumulated by bacteria via high affinity haem-uptake systems. The same uptake systems can be used to deliver antibiotic-porphyrin and antibacterial peptide-porphyrin conjugates. Haemin, the most well known natural porphyrin, possesses a significant antibacterial activity that is augmented by the presence of physiological concentrations of hydrogen peroxide or a reducing agent. Natural and synthetic porphyrins have relatively low toxicity in vitro and in vivo. The ability for numerous chemical modifications and the large number of different mechanisms by which porphyrins affect microbial and viral pathogens place porphyrins into a group of co…

Overview

Integrity signals

Registry

Crossref · 10.1517/13543784.10.2.309

Cites

7 of 7 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 7 references

Research works printed but not linked: 80

  1. 10.1097/00002030-198906000-00014 · DOI
  2. 10.3109/03602539308993973 · DOI
  3. BERNSTEIN LR, 1998, Pharmacol. Rev., 50, 665
  4. BERTOLINI G, 1993, Laser. Life Sci., 5, 267
  5. BERTOLONI G, 1992, Microbial., 71, 33
  6. 10.1111/j.1751-1097.1984.tb08864.x · DOI
  7. BERTOLONI G, 1989, J. Gen. Microbial, 135, 957
  8. 10.1111/j.1751-1097.1997.tb07964.x · DOI
  9. 10.1039/cs9952400019 · DOI
  10. 10.1039/jm9930300323 · DOI
  11. BRACKEN CS, 1999, J. Bacterial., 181, 6063, 10.1128/JB.181.19.6063-6072.1999 · DOI
  12. CALVIN M, 1969, Oxford University Press, New York, USA, 9
  13. 10.1002/jps.2600820502 · DOI
  14. 10.1021/bi00311a022 · DOI
  15. 10.1111/j.1751-1097.1982.tb04393.x · DOI
  16. 10.1016/S0022-328X(00)99222-2 · DOI
  17. 10.1021/jm00034a007 · DOI
  18. 10.1021/jm00096a020 · DOI
  19. 10.1177/095632029200300505 · DOI
  20. 10.1016/0003-9969(92)90058-G · DOI
  21. 10.1093/jnci/90.12.889 · DOI · Paper page
  22. 10.1046/j.1365-2958.2000.01818.x · DOI · Paper page
  23. 10.1016/S0891-5849(96)00499-6 · DOI · Paper page
  24. 10.1016/0014-5793(90)81129-C · DOI
  25. 10.1016/S1074-5521(96)90167-2 · DOI
  26. 10.1016/1011-1344(95)07201-2 · DOI
  27. 10.1007/BF00690163 · DOI
  28. HUGHES TE, 1992, Ann.Pharmacol., 26, 354, 10.1177/106002809202600310 · DOI
  29. JENKINS RD, 1985, J. Clin. Microbial, 22, 369, 10.1128/JCM.22.3.369-374.1985 · DOI
  30. JORI G, 1984, In: Topics in Photomedicine. Smith KC (Ed.), 183
  31. KAPLAN ML, 1976, J. Clin. Microbial., 4, 343, 10.1128/jcm.4.4.343-348.1976 · DOI
  32. LABBE RF, 1977, Clin. Chem., 23, 256, 10.1093/clinchem/23.2.256b · DOI
  33. 10.1111/j.1574-6968.1993.tb06444.x · DOI
  34. 10.1126/science.186.4167.936 · DOI
  35. 10.1073/pnas.88.5.1756 · DOI
  36. LIGHT WR, 1990, J. Biol. Chem., 265, 15623, 10.1016/S0021-9258(18)55443-0 · DOI
  37. 10.1016/0003-2697(87)90458-1 · DOI · Paper page
  38. 10.1016/0022-1759(92)90014-K · DOI
  39. MAINES MD: Herne oxygenase: clinical applications and functions. CRC Press, Inc. Boca Raton, USA (1992).
  40. 10.1016/1011-1344(90)85044-W · DOI
  41. 10.1016/1011-1344(90)85115-D · DOI
  42. 10.1128/AAC.44.3.522-7.2000 · DOI
  43. MINNOCK A VERNON, 1996, Use of a cationic water-soluble zinc phthalocyanine to photo inactivate both Gram-positive and Gram-negative bacteria. J. Photochem. Photobiol. B Biol., 32, 159
  44. 10.1016/1011-1344(95)07147-4 · DOI
  45. MILGROM LR: The Colours of Life. Oxford University Press, New York, USA (1997).
  46. 10.1111/j.1751-1097.1991.tb03669.x · DOI
  47. MOORE DG, 1980, Infect. Immun., 27, 418, 10.1128/IAI.27.2.418-423.1980 · DOI
  48. NELLY AN, 2000, J Clin. Microbial, 38, 724, 10.1128/JCM.38.2.724-726.2000 · DOI
  49. 10.1126/science.8153625 · DOI
  50. 10.1111/j.1751-1097.1995.tb05279.x · DOI
  51. 10.1111/j.1751-097.1992.tb04213.x · DOI
  52. 10.1111/j.1574-6968.1987.tb02632.x · DOI
  53. 10.1007/BF01568137 · DOI · Paper page
  54. 10.1016/1011-1344(93)80002-Q · DOI
  55. 10.1111/j.1751-1097.1988.tb02844.x · DOI
  56. 10.1097/00005650-198902000-00009 · DOI
  57. 10.1126/science.287.5457.1503 · DOI
  58. PROCTOR RA, 1994, Infect. Agents Dis., 3, 302
  59. 10.1086/418170 · DOI
  60. SANTUS R, 1998, Clin. Hemorh. Microcirc., 18, 299
  61. 10.1111/j.1365-2958.1993.tb01208.x · DOI
  62. 10.1111/j.1751-1097.1990.tb08688.x · DOI
  63. STAUDINGER R, 1996, Proc. Assoc. Am. Physicians, 108, 47
  64. 10.1111/j.1365-2958.1994.tb00465.x · DOI · Paper page
  65. STOJILJKOVIC I, 1992, EMBO J, 11, 4359, 10.1002/j.1460-2075.1992.tb05535.x · DOI
  66. 10.1016/S0960-894X(98)00536-8 · DOI
  67. SOUKOS NS, 1998, Antimi-crab. Agents Chemother., 42, 2595, 10.1128/AAC.42.10.2595 · DOI
  68. 10.1016/S1011-1344(99)00062-7 · DOI
  69. 10.1111/j.1751-1097.1988.tb02704.x · DOI
  70. 10.1042/bj1800327 · DOI
  71. 10.1016/0006-291X(87)90414-1 · DOI
  72. VAN DER MEULEN FW, IBRAHIM K,, 1997, Photodynamic destruction of Haemophilus parainfluenzae by endogenously produced porphyrins. J. Photochem. Photobiol. B, 40, 204
  73. 10.1093/infdis/151.1.166 · DOI
  74. 10.1016/1011-1344(93)80079-O · DOI
  75. 10.1093/jac/42.1.13 · DOI
  76. 10.1039/cs9962500351 · DOI
  77. 10.1016/S1369-5274(00)00078-3 · DOI · Paper page
  78. 10.1016/0968-0004(90)90304-T · DOI
  79. 10.1093/clinids/16.Supplement_4.S414 · DOI
  80. 10.1128/JB.182.2.439-447.2000 · DOI · Paper page

Cited by

Sorted by citations

Metadata

Authors
Stojiljkovic, I., Evavold, B. D., & Kumar, V.
Venue
Expert Opinion on Investigational Drugs
Publisher
Informa Healthcare
Published
2001-02
Volume
10
Issue
2
Pages
309-320
ISSN
  • 1354-3784
  • 1744-7658
DOI
10.1517/13543784.10.2.309
Cited by
209
References
7
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review