Review of long-acting stimulants in the treatment of attention deficit hyperactivity disorder
Abstract
A number of long-acting medications for the treatment of attention deficit hyperactivity disorder (ADHD) have recently been developed and approved for use in the US. These compounds are intended to optimize and maintain ADHD symptom control throughout the day, while eliminating problems associated with short-acting medications, such as the need for in-school, midday or multiple daily doses. Recent reports confirm that the safety and tolerability of long-acting medications are similar to those of short-acting medications, although long-acting medications appear to have a lower risk of abuse and diversion and may be associated with significant improvements in medication adherence. Distinctions can be made among the long-acting medications with regard to the onset, magnitude and duration of their clinical effects. Recognition of these differences is important for individualizing treatment for patients with ADHD.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Studies have found that extended-release stimulants are not diverted or misused in the same manner as immediate-release stimulants.
“If diversion or misuse of medication is a concern, studies have found that extended-release stimulants are not diverted or misused in the same manner as immediate-release stimulants [122].”
From Adult ADHD and comorbid disorders: clinical implications of a dimensional approach (2017) · cites this paper as [122]
Cites
BIEDERMAN, J., MONUTEAUX, M. C., MICK, E., SPENCER, T., WILENS, T. E., SILVA, J. M., SNYDER, L. E., & FARAONE, S. V. (2006) · Psychological Medicine · doi:10.1017/s0033291705006410 · Cited by 850 · see citing works
MTA Cooperative Group (2004) · Pediatrics · doi:10.1542/peds.113.4.754 · Cited by 589 · see citing works
Kelsey, D. K., Sumner, C. R., Casat, C. D., Coury, D. L., Quintana, H., Saylor, K. E., Sutton, V. K., Gonzales, J., Malcolm, S. K., Schuh, K. J., et al. (2004) · Pediatrics · doi:10.1542/peds.114.1.e1 · Cited by 464 · see citing works
Spencer, T., Heiligenstein, J. H., Biederman, J., Faries, D. E., Kratochvil, C. J., Conners, C. K., & Potter, W. Z. (2002) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v63n1209 · Cited by 333 · cited 2× · see citing works
“Efficacy of once- or twice-daily dosing of ATM for ADHD has been shown in placebo-controlled trials with children, adolescents, and adults [59-64].”
Biederman, J., Mick, E., Surman, C., Doyle, R., Hammerness, P., Harpold, T., Dunkel, S., Dougherty, M., Aleardi, M., & Spencer, T. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.09.011 · Cited by 267 · see citing works
Weiss, M., Tannock, R., Kratochvil, C., Dunn, D., Velez-Borras, J., Thomason, C., Tamura, R., Kelsey, D., Stevens, L., & Allen, A. J. (2005) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/01.chi.0000163280.47221.c9 · Cited by 147 · see citing works
Perwien, A. R., Hall, J., Swensen, A., & Swindle, R. (2004) · Journal of Managed Care Pharmacy · doi:10.18553/jmcp.2004.10.2.122 · Cited by 136 · see citing works
McGough, J. J., Wigal, S. B., Abikoff, H., Turnbow, J. M., Posner, K., & Moon, E. (2006) · Journal of Attention Disorders · doi:10.1177/1087054705284089 · Cited by 103 · see citing works
Assessment of Adherence Measures with Different Stimulants Among Children and Adolescents
Sanchez, R. J., Crismon, M. L., Barner, J. C., Bettinger, T., & Wilson, J. P. (2005) · Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.2005.25.7.909 · Cited by 101 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Adult ADHD and comorbid disorders: clinical implications of a dimensional approach
Katzman, M. A., Bilkey, T. S., Chokka, P. R., Fallu, A., & Klassen, L. J. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1463-3 · Cited by 732 · see citing works
Factors associated with treatment nonadherence among US bipolar disorder patients
Baldessarini, R. J., Perry, R., & Pike, J. (2008) · Human Psychopharmacology: Clinical and Experimental · doi:10.1002/hup.908 · Cited by 198 · see citing works
Mizuno, K., Yoneda, T., Komi, M., Hirai, T., Watanabe, Y., & Tomoda, A. (2013) · NeuroImage: Clinical · doi:10.1016/j.nicl.2013.03.004 · Cited by 30 · see citing works
Wigal, S. B., Kollins, S. H., Childress, A. C., & Adeyi, B. (2010) · Child and Adolescent Psychiatry and Mental Health · doi:10.1186/1753-2000-4-32 · Cited by 23 · see citing works
Lisdexamfetamine dimesylate: a new option in stimulant treatment for ADHD
Dew, R. E., & Kollins, S. H. (2010) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2010.531009 · Cited by 14 · see citing works
- Authors
- Weisler, R. H.
- Affiliations
- Duke Medical Center (US)
- Corresponding author
- Weisler, Richard H
- Venue
- Expert Opinion on Pharmacotherapy
- Publisher
- Informa Healthcare
- Published
- 2007-04
- Volume
- 8
- Issue
- 6
- Pages
- 745-758
- ISSN
- 1465-6566 (ISSN-L)
- 1744-7666
- OpenAlex
- W2098401458
- Cited by
- 22
- References
- 9
- Citations by year
- 2023: 1 · 2021: 2 · 2017: 1 · 2014: 3 · 2013: 1 · 2012: 1
- FWCI
- 2.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Expert Opinion on Pharmacotherapy (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pharmaceutical studies and practices
- Health Sciences › Medicine › Pharmacology › Pharmacology and Obesity Treatment
- Keywords
- attention deficit hyperactivity disorder, long-acting stimulants, ADHD medication, medication adherence, drug safety and tolerability, personalized treatment, symptom management
- MeSH terms
- Central Nervous System Stimulants, Attention Deficit Disorder with Hyperactivity, Clinical Trials as Topic, Delayed-Action Preparations, Drug Administration Schedule, Humans, Treatment Outcome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
