The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
MicroRNA identification in plasma and serum: a new tool to diagnose and monitor diseases
Abstract
MicroRNAs (miRNAs) are a class of small noncoding RNAs that regulate gene expression at the posttranscriptional level by degrading or blocking translation of messenger RNA (mRNA) targets. MiRNAs play important regulatory roles in a variety of cellular functions as well as in several diseases, including cancer. MiRNA-specific expression profiles have been reported for several pathological conditions. Recently, the discovery of miRNAs in serum opens up the possibility of using miRNAs as biomarkers of disease. In this review, we discuss the potential use of miRNAs as clinically diagnostic biomarkers of various cancers and other diseases as well as the approaches used to detect these molecules in serum and plasma.
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Cites
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The functions of animal microRNAs
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Self-citationCombinatorial microRNA target predictions
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MicroRNA Gene Expression Deregulation in Human Breast Cancer
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Self-citationSilencing of microRNAs in vivo with ‘antagomirs’
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Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
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Cited by
Non-coding RNAs and cancer: microRNAs and beyond
Raia, R. M., & Calin, G. A. (2011) · Journal of Nucleic Acids Investigation · doi:10.4081/jnai.2011.e5 · Cited by 3,382
Self-citationThe MicroRNA Spectrum in 12 Body Fluids
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An unconventional role for miRNA: let-7 activates toll-like receptor 7 and causes neurodegeneration
Lehmann, S. M., Krüger, C., Park, B., Derkow, K., Rosenberger, K., Baumgart, J., Trimbuch, T., Eom, G., Hinz, M., Kaul, D., et al. (2012) · Nature Neuroscience · doi:10.1038/nn.3113 · Cited by 786
Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation
Li, D., Liu, J., Guo, B., Liang, C., Dang, L., Lu, C., He, X., Cheung, H. Y.-S., Xu, L., Lu, C., et al. (2016) · Nature Communications · doi:10.1038/ncomms10872 · Cited by 588
Haemolysis during sample preparation alters microRNA content of plasma
Kirschner, M. B., Kao, S. C., Edelman, J. J., Armstrong, N. J., Vallely, M. P., van Zandwijk, N., & Reid, G. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024145 · Cited by 569
Metadata
- Authors
- Cortez, M. A., & Calin, G. A.
- Venue
- Expert Opinion on Biological Therapy
- Publisher
- Informa Healthcare
- Published
- 2009-05-09
- Volume
- 9
- Issue
- 6
- Pages
- 703-711
- ISSN
- 1471-2598 (ISSN-L)
- 1744-7682
- OpenAlex
- W2060037353
- Cited by
- 436
- References
- 13
- FWCI
- 11.07
- Type
- journal article
- Language
- en
- Open access
- closed
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