Developments in liposomal drug delivery systems

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

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Diffusion of univalent ions across the lamellae of swollen phospholipids

Bangham, A. D., Standish, M. M., & Watkins, J. C. (1965) · Journal of Molecular Biology · doi:10.1016/s0022-2836(65)80093-6 · Cited by 4,664 · see citing works

Long-Circulating and Target-Specific Nanoparticles: Theory to Practice

Moghimi, S. M., Hunter, A. C., & Murray, J. C. (2001) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01494-7 · Cited by 3,521 · see citing works

CpG motifs in bacterial DNA trigger direct B-cell activation

Krieg, A. M., Yi, A.-K., Matson, S., Waldschmidt, T. J., Bishop, G. A., Teasdale, R., Koretzky, G. A., & Klinman, D. M. (1995) · Nature · doi:10.1038/374546a0 · Cited by 3,508 · see citing works

Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model

Arap, W., Pasqualini, R., & Ruoslahti, E. I. (1998) · Science · doi:10.1126/science.279.5349.377 · Cited by 2,040 · see citing works

Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes

Klibanov, A. L., Maruyama, K., Torchilin, V. P., & Huang, L. (1990) · FEBS Letters · doi:10.1016/0014-5793(90)81016-h · Cited by 2,030 · see citing works

Lipid polymorphism and the functional roles of lipids in biological membranes

Cullis, P. R., & KRUIJFF, B. D. (1979) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(79)90012-1 · Cited by 1,865 · see citing works

Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size.

Yuan, F., Dellian, M., Fukumura, D., Leunig, M., Berk, D. A., Torchilin, V. P., & Jain, R. K. (1995) · PubMed · Cited by 1,706 · see citing works

Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy.

Papahadjopoulos, D., Allen, T. M., Gabizón, A., Mayhew, E. G., Matthay, K. K., Huang, S. K., Lee, K. D., Woodle, M. C., Lasiç, D. D., & Redemann, C. T. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.24.11460 · Cited by 1,621 · see citing works

Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid

Zabner, J., Fasbender, A., Moninger, T., Poellinger, K. A., & Welsh, M. J. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.32.18997 · Cited by 1,408 · see citing works

Biochemistry of Lipids, Lipoproteins and Membranes

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Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo

Allen, T. M., Hansen, C., Martin, F., Redemann, C. T., & Yau‐Young, A. O. (1991) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(91)90246-5 · Cited by 1,392 · see citing works

Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes.

Gabizón, A., Catane, R., Uziely, B., Kaufman, B., Safra, T., Cohen, R., Martin, F., Huang, A., & Barenholz, Y. (1994) · PubMed · Cited by 1,382 · see citing works

An Inverted Hexagonal Phase of Cationic Liposome-DNA Complexes Related to DNA Release and Delivery

Koltover, I., Salditt, T., Rädler, J. O., & Safinya, C. R. (1998) · Science · doi:10.1126/science.281.5373.78 · Cited by 1,336 · see citing works

Optimizing Liposomes for Delivery of Chemotherapeutic Agents to Solid Tumors

Drummond, D. C., Meyer, O., Hong, K., Kirpotin, D. B., & Papahadjopoulos, D. (1999) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01426-1 · Cited by 1,265 · see citing works

Mechanism of DNA Release from Cationic Liposome/DNA Complexes Used in Cell Transfection,

Xu, Y., & Szoka, F. C. (1996) · Biochemistry · doi:10.1021/bi9602019 · Cited by 1,136 · see citing works

Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors.

Gabizón, A., & Papahadjopoulos, D. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.18.6949 · Cited by 1,134 · see citing works

Barriers to Drug Delivery in Solid Tumors

Jain, R. K. (1994) · Scientific American · doi:10.1038/scientificamerican0794-58 · Cited by 1,074 · see citing works

The conformation of membranes

Lipowsky, R. (1991) · Nature · doi:10.1038/349475a0 · Cited by 993 · see citing works

Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases.

Haran, G., Cohen, R., Bar, L. K., & Barenholz, Y. (1993) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(93)90105-9 · Cited by 934 · see citing works

Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft.

Yuan, F., Leunig, M., Huang, S. K., Berk, D. A., Papahadjopoulos, D., & Jain, R. K. (1994) · PubMed · Cited by 908 · see citing works

Physical properties of the fluid lipid-bilayer component of cell membranes: a perspective

Bloom, M., Evans, E. A., & Mouritsen, O. G. (1991) · Quarterly Reviews of Biophysics · doi:10.1017/s0033583500003735 · Cited by 872 · see citing works

Transport of molecules across tumor vasculature

Jain, R. K. (1987) · Cancer and Metastasis Reviews · doi:10.1007/bf00047468 · Cited by 869 · see citing works

A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model.

Needham, D., Anyarambhatla, G., Kong, G., & Dewhirst, M. W. (2000) · PubMed · Cited by 746 · see citing works

Improved DNA: liposome complexes for increased systemic delivery and gene expression

Templeton, N. S., Lasiç, D. D., Frederik, P. M., Strey, H. H., Roberts, D. D., & Pavlakis, G. N. (1997) · Nature Biotechnology · doi:10.1038/nbt0797-647 · Cited by 740 · see citing works

Large unilamellar liposomes with low uptake into the reticuloendothelial system

Allen, T. M., & Chonn, A. (1987) · FEBS Letters · doi:10.1016/0014-5793(87)80506-9 · Cited by 729 · see citing works

Liposomes for the sustained drug release in vivo

Blume, G., & Cevc, G. (1990) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(90)90440-y · Cited by 701 · see citing works

Liposomes as immunological adjuvants

Allison, A. C., & Gregoriadis, G. C. (1974) · Nature · doi:10.1038/252252a0 · Cited by 676 · see citing works

Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size.

Kong, G., Braun, R. D., & Dewhirst, M. W. (2000) · PubMed · Cited by 630 · see citing works

Engineering liposomes for drug delivery: progress and problems

Gregoriadis, G. C. (1995) · Trends in biotechnology · doi:10.1016/s0167-7799(00)89017-4 · Cited by 626 · see citing works

Lipid composition and permeability of liposomes

de Gier, J., Mandersloot, J. G., & Deenen, L. L. M. V. (1968) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(68)90056-4 · Cited by 611 · see citing works

On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids

Hafez, I., Maurer, N., & Cullis, P. R. (2001) · Gene Therapy · doi:10.1038/sj.gt.3301506 · Cited by 601 · see citing works

Effect of the cholesterol content of small unilamellar liposomes on their stability in vivo and in vitro

Kirby, C. J., Clarke, J., & Gregoriadis, G. (1980) · Biochemical Journal · doi:10.1042/bj1860591 · Cited by 592 · see citing works

Fate and behavior of liposomes in vivo: a review of controlling factors.

Senior, J. H. (1987) · PubMed · Cited by 592 · see citing works

Pharmacokinetics of stealth versus conventional liposomes: effect of dose

Allen, T. M., & Hansen, C. (1991) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(91)90201-i · Cited by 579 · see citing works

Virus treatment questioned after gene therapy death

Lehrman, S. (1999) · Nature · doi:10.1038/43977 · Cited by 576 · cited 1× · see citing works

Influence of surface hydrophilicity of liposomes on their interaction with plasma protein and clearance from the circulation: Studies with poly(ethylene glycol)-coated vesicles

Senior, J. H., Delgado, C., Fisher, D., Tilcock, C., & Gregoriadis, G. (1991) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(91)90337-8 · Cited by 521 · see citing works

Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release.

Kong, G., Anyarambhatla, G., Petros, W. P., Braun, R. D., Colvin, O. M., Needham, D., & Dewhirst, M. W. (2000) · PubMed · Cited by 505 · see citing works

Current status of pH-sensitive liposomes in drug delivery

Drummond, D. C., Zignani, M., & Leroux, J. (2000) · Progress in Lipid Research · doi:10.1016/s0163-7827(00)00011-4 · Cited by 478 · see citing works

Tumor Infarction in Mice by Antibody-Directed Targeting of Tissue Factor to Tumor Vasculature

Huang, X., Molema, G., King, S., Watkins, L. R., Edgington, T. S., & Thorpe, P. E. (1997) · Science · doi:10.1126/science.275.5299.547 · Cited by 477 · see citing works

Targeting Folate Receptor with Folate Linked to Extremities of Poly(ethylene glycol)-Grafted Liposomes: In Vitro Studies

Gabizón, A., Horowitz, A. T., Goren, D., Tzemach, D., Mandelbaum-Shavit, F., Qazen, M. M., & Zalipsky, S. (1999) · Bioconjugate Chemistry · doi:10.1021/bc9801124 · Cited by 467 · see citing works

The Fate of Plasmid DNA After Intravenous Injection in Mice: Involvement of Scavenger Receptors in Its Hepatic Uptake

Kawabata, K., Takakura, Y., & Hashida, M. (1995) · Pharmaceutical Research · doi:10.1023/a:1016248701505 · Cited by 456 · see citing works

Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures

Semple, S. C., Klimuk, S. K., Harasym, T. O., Dos Santos, N., Ansell, S. M., Wong, K. F., Maurer, N., Stark, H., Cullis, P. R., Hope, M. J., et al. (2001) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(00)00343-6 · Cited by 454 · see citing works

The polymorphic phase behaviour of phosphatidylethanolamines of natural and synthetic origin. A 31P NMR study

Cullis, P. R., & KRUIJFF, B. D. (1978) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(78)90109-8 · Cited by 427 · see citing works

Medical Applications of Liposomes

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Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery

Liu, Y., Mounkes, L. C., Liggitt, H. D., et al. (1997) · Nature Biotechnology · doi:10.1038/nbt0297-167 · Cited by 405 · see citing works

Interactions of liposomes and lipid-based carrier systems with blood proteins: Relation to clearance behaviour in vivo

Semple, S. C., Chonn, A., & Cullis, P. R. (1998) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(97)00128-2 · Cited by 403 · see citing works

Endocytosis of liposomes and intracellular fate of encapsulated molecules: Encounter with a low pH compartment after internalization in coated vesicles

Straubinger, R. M., Hong, K., Friend, D. S., & Papahadjopoulos, D. (1983) · Cell · doi:10.1016/0092-8674(83)90291-x · Cited by 393 · see citing works

Doxorubicin Encapsulated in Liposomes Containing Surface‐Bound Polyethylene Glycol: Pharmacokinetics, Tumor Localization, and Safety in Patients with AIDS‐Related Kaposi's Sarcoma

Northfelt, D., Martin, F. J., Working, P. K., Volberding, P. A., Russell, J., Newman, M., Amantea, M., & Kaplan, L. D. (1996) · The Journal of Clinical Pharmacology · doi:10.1002/j.1552-4604.1996.tb04152.x · Cited by 377 · see citing works

Phosphatodylethanolamine liposomes: drug delivery, gene transfer and immunodiagnostic applications

Litzinger, D. C., & Huang, L. (1992) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(92)90039-d · Cited by 368 · see citing works

Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes

Friend, D. S., Papahadjopoulos, D., & Debs, R. J. (1996) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(95)00219-7 · Cited by 352 · see citing works

Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection

Li, S., Tseng, W.-C., Stolz, D. B., Wu, S.-Y., Watkins, S. C., & Huang, L. (1999) · Gene Therapy · doi:10.1038/sj.gt.3300865 · Cited by 351 · see citing works

Role of cholesterol in membranes effects on phospholipid-protein interactions, membrane permeability and enzymatic activity

Papahadjopoulos, D., Cowden, M., & Kimelberg, H. K. (1973) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(73)90280-0 · Cited by 337 · see citing works

Gene therapy: the first decade

Mountain, A. (2000) · Trends in biotechnology · doi:10.1016/s0167-7799(99)01416-x · Cited by 335 · see citing works

Fighting Cancer by Attacking its Blood Supply

Folkman, J. (1996) · Scientific American · doi:10.1038/scientificamerican0996-150 · Cited by 328 · see citing works

Liposomes for Gene Delivery

Liu, D. (2004) · Dalian Minzu Xueyuan xuebao · Cited by 326 · see citing works

Structure and Function of Lipid-DNA Complexes for Gene Delivery

Chesnoy, S., & Huang, L. (2000) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.29.1.27 · Cited by 312 · see citing works

Attachment of antibodies to sterically stabilized liposomes: evaluation, comparison and optimization of coupling procedures

Hansen, C. B., Kao, G. Y., Moase, E. H., Zalipsky, S., & Allen, T. M. (1995) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(95)00138-s · Cited by 309 · see citing works

Pharmacokinetics of long-circulating liposomes

Allen, T. M., Hansen, C. B., & de Menezes, D. E. L. (1995) · Advanced Drug Delivery Reviews · doi:10.1016/0169-409x(95)00029-7 · Cited by 306 · see citing works

Stabilized plasmid-lipid particles: construction and characterization

Wheeler, J. J., Palmer, L., Ossanlou, M., MacLachlan, I., Graham, R. W., Zhang, Y. P., Hope, M. J., Scherrer, P., & Cullis, P. R. (1999) · Gene Therapy · doi:10.1038/sj.gt.3300821 · Cited by 300 · see citing works

Insertion of poly(ethylene glycol) derivatized phospholipid into pre‐formed liposomes results in prolonged in vivo circulation time

Uster, P. S., Allen, T. M., Daniel, B. E., Mendez, C. J., Newman, M. S., & Zhu, G. Z. (1996) · FEBS Letters · doi:10.1016/0014-5793(96)00452-8 · Cited by 298 · see citing works

Serum opsonins and liposomes: their interaction and opsonophagocytosis.

Hm, P. (1992) · PubMed · Cited by 298 · see citing works

Microscopic localization of sterically stabilized liposomes in colon carcinoma-bearing mice.

Huang, S. K., Lee, K. D., Hong, K., Friend, D. S., & Papahadjopoulos, D. (1992) · PubMed · Cited by 297 · see citing works

Homing of liposomes to target cells

Gregoriadis, E. G., & Neerunjun, D. (1975) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(75)80180-x · Cited by 294 · see citing works

Complexes between cationic liposomes and DNA visualized by cryo-TEM

Gustafsson, J., Arvidson, G., Karlsson, G., & Almgren, M. (1995) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(95)80018-b · Cited by 290 · see citing works

Molecular structure and function

Lipscomb, W. N. (1991) · International Journal of Quantum Chemistry · doi:10.1002/qua.560400706 · Cited by 290 · see citing works

A new strategy for attachment of antibodies to sterically stabilized liposomes resulting in efficient targeting to cancer cells

Allen, T. M., Brandeis, E., Hansen, C. B., Kao, G. Y., & Zalipsky, S. (1995) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(95)00085-h · Cited by 288 · see citing works

Specific targeting with poly(ethylene glycol)-modified liposomes: coupling of homing devices to the ends of the polymeric chains combines effective target binding with long circulation times

Blume, G., Cevc, G., Crommelin, M. D. J. A., Bakker‐Woudenberg, I. A. J. M., Kluft, C., & Storm, G. (1993) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(93)90039-3 · Cited by 282 · see citing works

Membrane bending energy concept of vesicle‐ and cell‐shapes and shape‐transitions

Sackmann, E. (1994) · FEBS Letters · doi:10.1016/0014-5793(94)00484-6 · Cited by 281 · see citing works

Thermosensitive liposomes: Extravasation and release of contents in tumor microvascular networks

Gaber, M. H., Wu, N. Z., Hong, K., Huang, S. K., Dewhirst, M. W., & Papahadjopoulos, D. (1996) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/s0360-3016(96)00389-6 · Cited by 271 · see citing works

Roles of lipid polymorphism in intracellular delivery

Hafez, I. M., & Cullis, P. R. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00103-x · Cited by 267 · see citing works

The role of surface charge and hydrophilic groups on liposome clearance in vivo

Gabizon, A., & Papahadjopoulos, D. (1992) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(92)90061-p · Cited by 264 · see citing works

Gelation of liposome interior A novel method for drug encapsulation

Lasiç, D. D., Frederik, P. M., Stuart, M. C. A., Barenholz, Y., & McIntosh, T. J. (1992) · FEBS Letters · doi:10.1016/0014-5793(92)80947-f · Cited by 261 · see citing works

Doxorubicin physical state in solution and inside liposomes loaded via a pH gradient

Li, X., Hirsh, D. J., Cabral-Lilly, D., Zirkel, A., Gruner, S. M., Janoff, A. S., & Perkins, W. R. (1998) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(98)00175-8 · Cited by 259 · see citing works

The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: a survey

Madden, T. D., Harrigan, P. R., Tai, L. C. L., Bally, M. B., Mayer, L. D., Redelmeier, T. E., Loughrey, H. C., Tilcock, C., Reinish, L. W., & Cullis, P. R. (1990) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(90)90131-a · Cited by 255 · see citing works

Factors controlling the efficiency of cationic lipid-mediated transfection in vivo via intravenous administration

Liu, F., Qi, H., Huang, L., & Liu, D. (1997) · Gene Therapy · doi:10.1038/sj.gt.3300424 · Cited by 247 · see citing works

Disintegration of phosphatidylcholine liposomes in plasma as a result of interaction with high-density lipoproteins

Scherphof, G. L., Roerdink, F. H., Waite, M. B., & Parks, J. S. (1978) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(78)90025-9 · Cited by 246 · see citing works

Sphingomyelin-cholesterol liposomes significantly enhance the pharmacokinetic and therapeutic properties of vincristine in murine and human tumour models

Webb, M., Harasym, T. O., Masin, D., Bally, M. B., & Mayer, L. D. (1995) · British Journal of Cancer · doi:10.1038/bjc.1995.430 · Cited by 243 · see citing works

Gene therapy for cancer

Culver, K. W., & Blaese, R. M. (1994) · Trends in Genetics · doi:10.1016/0168-9525(94)90095-7 · Cited by 243 · see citing works

Recognition of liposomes by cells: In vitro binding and endocytosis mediated by specific lipid headgroups and surface charge density

Lee, K. D., Hong, K., & Papahadjopoulos, D. (1992) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(92)90086-2 · Cited by 241 · see citing works

The Inhibitory Role of CpG Immunostimulatory Motifs in Cationic Lipid Vector-Mediated Transgene Expression in Vivo

Tan, Y., Li, S., Pitt, B. R., & Huang, L. (1999) · Human Gene Therapy · doi:10.1089/10430349950017149 · Cited by 235 · see citing works

Spontaneous Entrapment of Polynucleotides upon Electrostatic Interaction with Ethanol-Destabilized Cationic Liposomes

Maurer, N., Wong, K. F., Stark, H., Louie, L. J., McIntosh, D. P., Wong, T., Scherrer, P., Semple, S. C., & Cullis, P. R. (2001) · Biophysical Journal · doi:10.1016/s0006-3495(01)76202-9 · Cited by 232 · see citing works

Physicochemical Characterization and Purification of Cationic Lipoplexes

Xu, Y., Hui, S. W., Frederik, P. M., & Szoka, F. C. (1999) · Biophysical Journal · doi:10.1016/s0006-3495(99)76894-3 · Cited by 229 · see citing works

Poly(ethylene glycol)−Lipid Conjugates Regulate the Calcium-Induced Fusion of Liposomes Composed of Phosphatidylethanolamine and Phosphatidylserine

Holland, J. W., Hui, C., Cullis, P. R., & Madden, T. D. (1996) · Biochemistry · doi:10.1021/bi952000v · Cited by 223 · see citing works

Reduced Inflammatory Response to Plasmid DNA Vectors by Elimination and Inhibition of Immunostimulatory CpG Motifs

Yew, N. S., Zhao, H., Wu, I., Song, A., Tousignant, J. D., Przybylska, M., & Cheng, S. H. (2000) · Molecular Therapy · doi:10.1006/mthe.2000.0036 · Cited by 221 · see citing works

In vitro and in vivo comparison of immunoliposomes made by conventional coupling techniques with those made by a new post-insertion approach

Iden, D. L., & Allen, T. M. (2001) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(01)00357-1 · Cited by 220 · see citing works

A Compendium of Vaccine Adjuvants and Excipients

Vogel, F. R., & Powell, M. F. (1995) · Pharmaceutical biotechnology · doi:10.1007/978-1-4615-1823-5_7 · Cited by 217 · see citing works

Influence of pH gradients on the transbilayer transport of drugs, lipids, peptides and metal ions into large unilamellar vesicles

Cullis, P. R., Hope, M. J., Bally, M. B., Madden, T. D., Mayer, L. D., & Fenske, D. B. (1997) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/s0304-4157(97)00006-3 · Cited by 212 · see citing works

Transmembrane gradient driven phase transitions within vesicles: lessons for drug delivery.

Lasic, D. D., Čeh, B., Stuart, M. C. A., Guo, L., Frederik, P. M., & Barenholz, Y. (1995) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(95)00159-z · Cited by 209 · see citing works

Liposomes with detachable polymer coating: destabilization and fusion of dioleoylphosphatidylethanolamine vesicles triggered by cleavage of surface‐grafted poly(ethylene glycol)

Kirpotin, D. B., Hong, K., Mullah, N. N., Papahadjopoulos, D., & Zalipsky, S. (1996) · FEBS Letters · doi:10.1016/0014-5793(96)00521-2 · Cited by 206 · see citing works

Lipid-DNA Complex Formation: Reorganization and Rupture of Lipid Vesicles in the Presence of DNA As Observed by Cryoelectron Microscopy

Huebner, S., Battersby, B. J., Grimm, R., & Cevc, G. (1999) · Biophysical Journal · doi:10.1016/s0006-3495(99)77467-9 · Cited by 203 · see citing works

Immunogenicity and pharmacokinetic attributes of poly(ethylene glycol)-grafted immunoliposomes

Harding, J. A., Engbers, C. M., Newman, M. S., Goldstein, N. I., & Zalipsky, S. (1997) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(97)00056-4 · Cited by 202 · see citing works

Liposomes and hyperthermia in mice: increased tumor uptake and therapeutic efficacy of doxorubicin in sterically stabilized liposomes.

Huang, S. K., Stauffer, P. R., Hong, K., Guo, J., Phillips, T. L., Huang, A., & Papahadjopoulos, D. (1994) · PubMed · Cited by 183 · see citing works

Immune effects and mechanisms of action of CpG motifs

Krieg, A. Μ. (2000) · Vaccine · doi:10.1016/s0264-410x(00)00249-8 · Cited by 182 · see citing works

ISCOMs: an adjuvant with multiple functions

Sjölander, A., Cox, J. C., & Barr, I. (1998) · Journal of Leukocyte Biology · doi:10.1002/jlb.64.6.713 · Cited by 179 · see citing works

Physical properties and functional roles of lipids in membranes

Cullis, P. R., Fenske, D. B., & Hope, M. J. (1996) · New comprehensive biochemistry · doi:10.1016/s0167-7306(08)60508-6 · Cited by 177 · see citing works

Immunoliposomes for the targeted delivery of antitumor drugs

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