Lipid nanoparticles for short interfering RNA delivery

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A microRNA in a Multiple-Turnover RNAi Enzyme Complex

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RNA-guided genetic silencing systems in bacteria and archaea

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Rational design of cationic lipids for siRNA delivery

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Delivery materials for siRNA therapeutics

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The use of gold nanoparticles to enhance radiotherapy in mice

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Regulatory RNAs in Bacteria

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Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients

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RNAi-mediated gene silencing in non-human primates

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Gold nanoparticles: a new X-ray contrast agent

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Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo

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Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms

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Interfering with disease: a progress report on siRNA-based therapeutics

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STRUCTURES AND FUNCTIONS OF MULTILIGAND LIPOPROTEIN RECEPTORS: Macrophage Scavenger Receptors and LDL Receptor-Related Protein (LRP)

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CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea

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Mechanisms and optimization of in vivo delivery of lipophilic siRNAs

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Safety and efficacy of RNAi therapy for transthyretin amyloidosis

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Passenger-Strand Cleavage Facilitates Assembly of siRNA into Ago2-Containing RNAi Enzyme Complexes

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Perspective: machines for RNAiPreprint

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CRISPR — a widespread system that provides acquired resistance against phages in bacteria and archaea

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Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft.

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Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

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Argonaute2 Cleaves the Anti-Guide Strand of siRNA during RISC Activation

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Evidence for the role of proteoglycans in cation-mediated gene transfer.

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Expression of therapeutic proteins after delivery of chemically modified mRNA in mice

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Inhibition of respiratory viruses by nasally administered siRNA

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RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

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Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection

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Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA

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Decreased plasma cholesterol and hypersensitivity to statins in mice lacking <i>Pcsk9</i>

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Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

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Correction of a genetic disease in mouse via use of CRISPR-Cas9

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In vivo activity of nuclease-resistant siRNAs

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Design of Noninflammatory Synthetic siRNA Mediating Potent Gene Silencing in Vivo

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Sequence-Specific Knockdown of EWS-FLI1 by Targeted, Nonviral Delivery of Small Interfering RNA Inhibits Tumor Growth in a Murine Model of Metastatic Ewing's Sarcoma

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Post-transcriptional gene silencing by siRNAs and miRNAs

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Molecular Basis for Target RNA Recognition and Cleavage by Human RISC

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Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells

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Biodegradable calcium phosphate nanoparticle with lipid coating for systemic siRNA delivery

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Kinetic Characterization of Ribonuclease-Resistant 2′-Modified Hammerhead Ribozymes

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Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low Toxicity

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Lipid-based systemic delivery of siRNA

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Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study

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Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures

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A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus

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Ligand-targeted liposomal anticancer drugs

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Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque

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Gold Nanoparticle Imaging and Radiotherapy of Brain Tumors in Mice

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The Liposomal Formulation of Doxorubicin

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The action of steroids and streptolysin S on the permeability of phospholipid structures to cations

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Triggered release from liposomes through magnetic actuation of iron oxide nanoparticle containing membranes

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Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA

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siRNA relieves chronic neuropathic pain

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A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium

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Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung

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Lipid polymorphism and the roles of lipids in membranes

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Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core

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Transferrin-Containing, Cyclodextrin Polymer-Based Particles for Tumor-Targeted Gene Delivery

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Chemical modification of siRNAs to improve serum stability without loss of efficacy

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