The DOI matches its Crossref record; 69 of the 69 references it cites were found in a registry or an index.
Ocular drug delivery
Abstract
Drug delivery to the eye is hampered by anatomical factors, including the corneal epithelium, the blood-aqueous barrier and the blood-retinal barrier. This review aims to outline the major routes of ocular drug delivery, including systemic, topical, periocular and intravitreal. The pharmacokinetics, the disadvantages and the clinical relevance of these drug delivery routes have been emphasised. Recent advances in surgical techniques, therapeutic approaches and material sciences have produced exciting new therapies for ocular diseases. The role of ophthalmic drug formulation in targeting the desired ocular tissue and enhancing drug delivery by the chosen route whilst minimising side effects is also discussed.
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Citations
Cites
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Permeability of cornea, sclera, and conjunctiva: A literature analysis for drug delivery to the eye
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Acute endophthalmitis following intravitreal triamcinolone acetonide injection
Moshfeghi, D. M., Kaiser, P. K., Scott, I. U., Sears, J. E., Benz, M., Sinesterra, J. P., Kaiser, R. S., Bakri, S. J., Maturi, R. K., Belmont, J., et al. (2003) · American Journal of Ophthalmology · doi:10.1016/s0002-9394(03)00483-5 · Cited by 397
FATAL BENZYL ALCOHOL POISONING IN A NEONATAL INTENSIVE CARE UNIT
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Human sclera: Thickness and surface area
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Self-citationPenetration Enhancers and Ocular Bioadhesives: Two New Avenues for Ophthalmic Drug Delivery
Kaur, I. P., & Smitha, R. (2002) · Drug Development and Industrial Pharmacy · doi:10.1081/ddc-120002997 · Cited by 305
Importance of the noncorneal absorption route in topical ophthalmic drug delivery.
Ahmed, I., & Patton, T. F. (1985) · PubMed · Cited by 287
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Cited by
Gaudana, R., Ananthula, H. K., Parenky, A., & Mitra, A. K. (2010) · The AAPS Journal · doi:10.1208/s12248-010-9183-3 · Cited by 1,406
A comprehensive insight on ocular pharmacokinetics
Agrahari, V., Mandal, A., Agrahari, V., Trinh, H. M., Joseph, M., Ray, A., Hadji, H., Mitra, R., Pal, D., & Mitra, A. K. (2016) · Drug Delivery and Translational Research · doi:10.1007/s13346-016-0339-2 · Cited by 462
Nanoparticles for drug delivery to the anterior segment of the eye
Janagam, D. R., Wu, L., & Lowe, T. L. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2017.04.001 · Cited by 341
Safety evaluation of ocular drug delivery formulations: Techniques and practical considerations
Short, B. G. (2008) · Toxicologic Pathology · doi:10.1177/0192623307310955 · Cited by 244
Drug and Gene Delivery to the Back of the Eye: From Bench to Bedside
Rowe-Rendleman, C. L., Durazo, S. A., Kompella, U. B., Rittenhouse, K. D., Di Polo, A., Weiner, A. L., Grossniklaus, H. E., Naash, M. I., Lewin, A. S., Horsager, A., et al. (2014) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.13-13707 · Cited by 120
Self-citation
Metadata
- Authors
- Ghate, D., & Edelhauser, H. F.
- Venue
- Expert Opinion on Drug Delivery
- Publisher
- Informa Healthcare
- Published
- 2006-02-28
- Volume
- 3
- Issue
- 2
- Pages
- 275-287
- ISSN
- 1742-5247 (ISSN-L)
- 1744-7593
- OpenAlex
- W2072399777
- Cited by
- 329
- References
- 69
- FWCI
- 8.56
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
