The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Mannose-targeted systems for the delivery of therapeutics
Abstract
BACKGROUND: The specific targeting of nanomedicines to mannose receptors, highly expressed in cells of the immune system, performs a useful strategy for improving the efficacy of vaccines and chemotherapy. OBJECTIVE: This review discusses the potential of mannose-targeted drug/antigen delivery systems for vaccination and treatment of diseases localized in macrophages and other antigen-presenting cells. METHODS: The first part of the review describes the characteristics, localization and functions of mannose receptors. The following sections are devoted to the description of different methods used to deliver therapeutic agents, including mannose conjugates and mannosylated carriers or particulates (i.e., liposomes, nanoparticles and niosomes). RESULTS/CONCLUSIONS: A general overview of published reports confirms the effectiveness of mannosylation strategies, although the optimization and full exploitation of mannose-targeted drug delivery systems would require a deeper understanding of the structure-activity relationship. In the near future, these nanomedicines have the potential to treat a number of diseases (including cancer) and improve the quality of life of patients.
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Cites
Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells
Nestle, F. O., Alijagic, S., Gilliet, M., Sun, Y., Grabbe, S., Dummer, R., Burg, G., & Schadendorf, D. (1998) · Nature Medicine · doi:10.1038/nm0398-328 · Cited by 2,862
C-type lectin receptors on dendritic cells and langerhans cells
Figdor, C. G., van Kooyk, Y., & Adema, G. J. (2002) · Nature Reviews Immunology · doi:10.1038/nri723 · Cited by 842
Self- and nonself-recognition by C-type lectins on dendritic cells
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Ligand recognition by antigen-presenting cell C-type lectin receptors
McGreal, E. P., Miller, J. L., & Gordon, S. (2005) · Current Opinion in Immunology · doi:10.1016/j.coi.2004.12.001 · Cited by 310
Casadevall, A., Cleare, W., Feldmesser, M., Glatman-Freedman, A., Goldman, D. L., Kozel, T. R., Lendvai, N., Mukherjee, J., Pirofski, L.-A., Rivera, J., et al. (1998) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.42.6.1437 · Cited by 298
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Huh, A. J., & Kwon, Y. J. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.07.002 · Cited by 1,864
Folate-targeted therapeutic and imaging agents for cancer
Low, P. S., & Kularatne, S. A. (2009) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2009.03.022 · Cited by 585
Folate-targeted therapies for cancer
Xia, W., & Low, P. S. (2010) · Journal of Medicinal Chemistry · doi:10.1021/jm100509v · Cited by 448
Targeted Liposomal Drug Delivery to Monocytes and Macrophages
Kelly, C., Jefferies, C., & Cryan, S.-A. (2011) · Journal of Drug Delivery · doi:10.1155/2011/727241 · Cited by 425
Designing spatial and temporal control of vaccine responses
Roth, G. A., Picece, V. C. T. M., Ou, B. S., Luo, W., Pulendran, B., & Appel, E. A. (2021) · Nature Reviews Materials · doi:10.1038/s41578-021-00372-2 · Cited by 316
Metadata
- Authors
- Irache, J. M., Salman, H. H., Gamazo, C., & Espuelas, S.
- Venue
- Expert Opinion on Drug Delivery
- Publisher
- Informa UK Limited
- Published
- 2008-06
- Volume
- 5
- Issue
- 6
- Pages
- 703-724
- ISSN
- 1742-5247 (ISSN-L)
- 1744-7593
- OpenAlex
- W1966009267
- Cited by
- 293
- References
- 6
- FWCI
- 4.79
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
