Cited by 1,997Memory and Neural MechanismsMemory Processes and InfluencesCognitive Functions and Memory

The DOI matches its Crossref record, with a small difference in title or year; 69 of the 69 references it cites were found in a registry or an index.

Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus

Open access

Zola-Morgan, S, Squire, LR, Amaral, DG·1986·The Journal of Neuroscience

DOI 10.1523/jneurosci.06-10-02950.1986PMC PMC6568782

Open this paper in CoChat — free account

Abstract

During the past 100 years clinical studies of amnesia have linked memory impairment to damage of the hippocampus. Yet the damage in these cases has not usually been confined to the hippocampus, and the status of memory functions has often been based on incomplete neuropsychological information. Thus, the human cases have until now left some uncertainty as to whether lesions limited to the hippocampus are sufficient to cause amnesia. Here we report a case of amnesia in a patient (R.B.) who developed memory impairment following an ischemic episode. During the 5 years until his death, R.B. exhibited marked anterograde amnesia, little if any retrograde amnesia, and showed no signs of cognitive impairment other than memory. Thorough histological examination revealed a circumscribed bilateral lesion involving the entire CA1 field of the hippocampus. Minor pathology was found elsewhere in the brain (e.g., left globus pallidus, right postcentral gyrus, left internal capsule), but the only damage that could be reasonably associated with the memory defect was the lesion in the hippocampus. To our knowledge, this is the first reported case of amnesia following a lesion limited to the hippocampus in which extensive neuropsychological and neuropathological analyses have been carried out.

Integrity signals

Registry

Crossref · 10.1523/jneurosci.06-10-02950.1986

Cites

69 of 69 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

LOSS OF RECENT MEMORY AFTER BILATERAL HIPPOCAMPAL LESIONS
Scoville, W. B., & Milner, B. (1957) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.20.1.11 · Cited by 7,322
Le test de copie d'une figure complexe
Osterrieth, P. M. (1944) · Medical Entomology and Zoology · Cited by 2,336
Hippocampus, space, and memory
Olton, D. S., Becker, J. T., & Handelmann, G. E. (1979) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00062713 · Cited by 2,018
Studies on the structure of the cerebral cortex. II. Continuation of the study of the ammonic system.
de Nó, R. L. (1934) · Cited by 1,974
A new model of bilateral hemispheric ischemia in the unanesthetized rat.
Pulsinelli, W. A., & Brierley, J. B. (1979) · Stroke · doi:10.1161/01.str.10.3.267 · Cited by 1,947
Cell Damage in the Brain: A Speculative Synthesis
Siesjö, B. K. (1981) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1981.18 · Cited by 1,807
EPILEPSY AND THE TEMPORAL LOBES
Margerison, J. H., & Corsellis, J. (1966) · Brain · doi:10.1093/brain/89.3.499 · Cited by 1,260
The information that amnesic patients do not forget.
Graf, P., Squire, L. R., & Mandler, G. (1984) · Journal of Experimental Psychology Learning Memory and Cognition · doi:10.1037//0278-7393.10.1.164 · Cited by 883
Self-citation
Disorders of Learning and Memory after Temporal Lobe Lesions in Man
Milner, B. A. (1972) · Neurosurgery · doi:10.1093/neurosurgery/19.cn_suppl_1.421 · Cited by 882
THE WERNICKE-KORSAKOFF SYNDROME
Russell, R. W. R. (1972) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.35.2.277 · Cited by 815

Show all 69 references

Sorted by citations

Items 601–700 of 1,006

Memory development and event-related brain potentials in children
Cycowicz, Y. M. (2000) · Biological Psychology · doi:10.1016/s0301-0511(00)00055-7 · Cited by 78
Disturbance of Membrane Function Preceding Ischemic Delayed Neuronal Death in the Gerbil Hippocampus
Kirino, T., Robinson, H. P. C., Miwa, A., Tamura, A., & Kawai, N. (1992) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1992.58 · Cited by 76
A Pilot Study Evaluating Presurgery Neuroanatomical Biomarkers for Postoperative Cognitive Decline after Total Knee Arthroplasty in Older Adults
Price, C. C., Tanner, J. J., Schmalfuss, I. M., GARVAN, C. W., Gearen, P., Dickey, D., Heilman, K. M., McDonagh, D. L., Libon, D. J., Leonard, C. M., et al. (2014) · Anesthesiology · doi:10.1097/aln.0000000000000080 · Cited by 75
Prominence of Direct Entorhinal–CA1 Pathway Activation in Sensorimotor and Cognitive Tasks Revealed by 2-DG Functional Mapping in Nonhuman Primate
Sybirska, E. H., Davachi, L., & Goldman‐Rakic, P. S. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-15-05827.2000 · Cited by 75
Effects of LY231617 and angiotensin IV on ischemia-induced deficits in circular water maze and passive avoidance performance in rats
Wright, J. W., Clemens, J. A., Panetta, J. A., Smalstig, E. B., Stubley, L., Kramár, E., Pederson, E. S., Mungall, B. H., & Harding, J. W. (1996) · Brain Research · doi:10.1016/0006-8993(95)01454-3 · Cited by 75
Intracarotid Amobarbital Procedure: I. Prediction of Decreased Modality‐Specific Memory Scores After Temporal Lobectomy
Wyllie, E., Naugel, R., Awad, I. A., Chelune, G. J., Lüders, H. O., Dinner, D. S., Skibinski, C. I., Ahl, J., & Portera‐Sánchez, A. (1991) · Epilepsia · doi:10.1111/j.1528-1157.1991.tb05542.x · Cited by 75
Neurochemical gradients along monkey sensory cortical pathways: calbindin‐immunoreactive pyramidal neurons in layers II and III
Kondo, H., Tanaka, K., Hashikawa, T., & Jones, E. G. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00844.x · Cited by 74
Persistent behavioral impairments and neuroinflammation following global ischemia in the rat
Langdon, K. D., Granter‐Button, S., & Corbett, D. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06513.x · Cited by 74
Alcohol-Induced Blackout
Rose, M. E., & Grant, J. E. (2010) · Journal of Addiction Medicine · doi:10.1097/adm.0b013e3181e1299d · Cited by 74
The Effects of Hydrocortisone on Cognitive and Neural Function A Behavioral and Event-Related Potential Investigation
Monk, C. S. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00384-0 · Cited by 72
Increased Hippocampal Excitability in the 3xTgAD Mouse Model for Alzheimer's Disease In Vivo
Davis, K. E., Fox, S., & Gigg, J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0091203 · Cited by 72
The challenges of understanding mammalian cognition and memory-based behaviours: an interactive learning and memory systems approach
McDonald, R. J., Hong, N. S., & Devan, B. D. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.09.014 · Cited by 79
Stability and plasticity of intrinsic membrane properties in hippocampal CA1 pyramidal neurons: effects of internal anions
Kaczorowski, C. C., Disterhoft, J. F., & Spruston, N. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.124586 · Cited by 73
Neurogenesis interferes with the retrieval of remote memories: Forgetting in neurocomputational terms
Weisz, V. I., & Argibay, P. F. (2012) · Cognition · doi:10.1016/j.cognition.2012.07.002 · Cited by 78
KIBRA and CLSTN2 polymorphisms exert interactive effects on human episodic memory
Preuschhof, C., Heekeren, H. R., Li, S., Sander, T., Lindenberger, U., & Bäckman, L. (2009) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2009.09.031 · Cited by 73
The performance of amnesic subjects on tests of delayed matching-to-sample and delayed matching-to-position
Holdstock, J. S., Shaw, C., & Aggleton, J. P. (1995) · Neuropsychologia · doi:10.1016/0028-3932(95)00145-x · Cited by 74
The Relationship between Retrograde and Anterograde Amnesia in Patients with Typical Global Amnesia
Mayes, A. R., Daum, I., Markowisch, H. J., & Sauter, B. (1997) · Cortex · doi:10.1016/s0010-9452(08)70001-7 · Cited by 74
N-methyl-d-aspartate receptor complex in the hippocampus of elderly, normal individuals and those with Alzheimer's disease
Ułas, J., Brunner, L. C., Geddes, J. W., Choe, W. S., & Cotman, C. W. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90075-d · Cited by 75
Preoperative training modifies radial maze performance in rats with ischemic hippocampal injury.
Volpe, B. T., Davis, H. P., & Colombo, P. J. (1989) · Stroke · doi:10.1161/01.str.20.12.1700 · Cited by 74
The accessible chromatin landscape of the murine hippocampus at single-cell resolutionPreprint
Sinnamon, J. R., Torkenczy, K. A., Linhoff, M. W., Vitak, S. A., Mulqueen, R. M., Pliner, H. A., Trapnell, C., Steemers, F. J., Mandel, G., & Adey, A. (2019) · Genome Research · doi:10.1101/gr.243725.118 · Cited by 70
A little history goes a long way toward understanding why we study consciousness the way we do today
LeDoux, J. E., Michel, M., & Lau, H. C. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1921623117 · Cited by 86
Long-Term Consequences of Severe Closed Head Injury on Episodic Memory
Zec, R. F., Zellers, D., Belman, J., Miller, J. G., Matthews, J. R., Ferneau-Belman, D., & ROBBS, R. S. (2001) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.23.5.671.1247 · Cited by 73
Fast (beta) rhythms in the hippocampus: A review
Leung, L.-W. S. (1992) · Hippocampus · doi:10.1002/hipo.450020202 · Cited by 77
Some Comments on the Special Cognitive Functions Claimed for the Hippocampus
Horel, J. A. (1994) · Cortex · doi:10.1016/s0010-9452(13)80198-0 · Cited by 73
Hippocampal neuron and glial cell numbers in Parkinson's disease—A stereological study
Joelving, F. C., Billeskov, R., Christensen, J. R., West, M. J., & Pakkenberg, B. (2006) · Hippocampus · doi:10.1002/hipo.20212 · Cited by 72
When “long-term memory” no longer means “forever”: Analysis of accelerated long-term forgetting in a patient with temporal lobe epilepsy
Jansari, A. S., Davis, K., McGibbon, T., Firminger, S., & Kapur, N. (2010) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2010.02.018 · Cited by 71
Prenatal ethanol exposure alters the modulation of the gamma-aminobutyric acidA1 receptor-gated chloride ion channel in adult rat offspring.
Allan, A. M., Wu, H., Paxton, L. L., & Savage, D. D. (1998) · PubMed · Cited by 72
Acetylcholinesterase fiber staining in the human hippocampus and parahippocampal gyrus
Green, R. C., & Mesulam, M. M. (1988) · The Journal of Comparative Neurology · doi:10.1002/cne.902730405 · Cited by 72
Hippocampal Injury and Alterations in Neuronal Chemokine Co-Receptor Expression in Patients With AIDS
Petito, C. K., Roberts, B., Cantando, J. D., Rabinstein, A. A., & DUNCAN, R. C. (2001) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/60.4.377 · Cited by 72
Pre- and Post-Ischemic Administration of Dizocilpine (MK-801) Reduces Cerebral Necrosis in the Rat
Rod, M., & Auer, R. N. (1989) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s031716710002919x · Cited by 72
Short-term memory for duration and distance in humans: Role of the hippocampus.
Kesner, R. P., & Hopkins, R. O. (2001) · Neuropsychology · doi:10.1037//0894-4105.15.1.58 · Cited by 71
β-Adrenergic receptor activation during distinct patterns of stimulation critically modulates the PKA-dependence of LTP in the mouse hippocampusPreprint
Gelinas, J. N., Tenorio, G., Lemon, N., Abel, T. G., & Nguyen, P. (2008) · Learning & Memory · doi:10.1101/lm.829208 · Cited by 71
Hippocampal neurons transplanted into ischemically lesioned hippocampus: anatomical assessment of survival, maturation and integration
Mudrick, L. A., & Baimbridge, K. G. (1991) · Experimental Brain Research · doi:10.1007/bf00228948 · Cited by 71
A Study of Amyloid-β and Phosphotau in Plaques and Neurons in the Hippocampus of Alzheimer’s Disease Patients
Furcila, D., DeFelipe, J., & Alonso‐Nanclares, L. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-180173 · Cited by 73
The protective effect of hyperbaric oxygen and Ginkgo biloba extract on A?25?35-induced oxidative stress and neuronal apoptosis in rats
Tian, X., Zhang, L., Wang, J., Dai, J., Shen, S., Yang, L., & Huang, P. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.12.026 · Cited by 70
Functional single-walled carbon nanotubes ‘CAR’ for targeting dopamine delivery into the brain of parkinsonian mice
Guo, Q., You, H., Yang, X., Lin, B., Zhu, Z., Lu, Z., Li, X., Zhao, Y. S., Mao, L., Shen, S., et al. (2017) · Nanoscale · doi:10.1039/c7nr02682j · Cited by 70
Blockade of hippocampal M1 muscarinic receptors impairs working memory performance of rats
Ohno, M., Yamamoto, T., & Watanabe, S. (1994) · Brain Research · doi:10.1016/0006-8993(94)91790-6 · Cited by 70
DEVELOPMENT OF FETAL HIPPOCAMPAL GRAFTS IN INTACT AND LESIONED HIPPOCAMPUS
Shetty, A. K., & Turner, D. A. (1996) · Progress in Neurobiology · doi:10.1016/s0301-0082(96)00048-2 · Cited by 70
A neuropsychological analysis of memory loss with age
Winocur, G. (1988) · Neurobiology of Aging · doi:10.1016/s0197-4580(88)80102-7 · Cited by 69
Cognitive Biology
Auletta, G. (2011) · doi:10.1093/acprof:oso/9780199608485.001.0001 · Cited by 91
The Neuropsychiatry and Neuropsychology Of Lipoid Proteinosis
Thornton, H. B., Nel, D. G., Thornton, D., van Honk, J., Baker, G. A., & Stein, D. J. (2008) · Journal of Neuropsychiatry · doi:10.1176/jnp.2008.20.1.86 · Cited by 69
Delayed Signal Propagation via CA2 in Rat Hippocampal Slices Revealed by Optical Recording
Sekino, Y., Obata, K., Tanifuji, M., Mizuno, M., & Murayama, J. (1997) · Journal of Neurophysiology · doi:10.1152/jn.1997.78.3.1662 · Cited by 69
Hippocampal and amygdaloid interactions in the nucleus accumbens
Groenewegen, H. J., Mulder, A. B., Beijer, A. V. J., Wright, C. I., Lopes, F. H. D. S., & Pennartz, C. M. A. (1999) · Psychobiology · doi:10.3758/bf03332111 · Cited by 70
Characterization of postischemic behavioral deficits in gerbils with and without hypothermic neuroprotection
Colbourne, F., Auer, R. N., & Sutherland, G. R. (1998) · Brain Research · doi:10.1016/s0006-8993(98)00612-x · Cited by 69
Ongoing Epileptiform Activity in the Post-Ischemic Hippocampus Is Associated with a Permanent Shift of the Excitatory–Inhibitory Synaptic Balance in CA3 Pyramidal Neurons
Epsztein, J., Milh, M., Bihi, R. I., Jorquera, I., Ben‐Ari, Y., Represa, A., & Crépel, V. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1666-06.2006 · Cited by 74
Distinctive Forms of Partial Retrograde Amnesia after Asymmetric Temporal Lobe Lesions: Possible Role of the Occipitotemporal Gyri in Memory
Eslinger, P. J., Easton, A. E., Grattan, L. M., & Hoesen, G. W. V. (1996) · Cerebral Cortex · doi:10.1093/cercor/6.3.530 · Cited by 69
Differential proliferative response in the postischemic hippocampus, temporal cortex, and olfactory bulb of young adult macaque monkeys
Tonchev, A. B., Yamashima, T., Zhao, L., & Okano, H. (2003) · Glia · doi:10.1002/glia.10209 · Cited by 68
Neuronal damage in the rat hippocampus in a new model of repeated reversible transient cerebral ischemia
Nakano, S., Kato, H., & Kogure, K. (1989) · Brain Research · doi:10.1016/0006-8993(89)90448-4 · Cited by 69
Protocol for volumetric segmentation of medial temporal structures using high‐resolution 3‐D magnetic resonance imaging
Bonilha, L., Kobayashi, E., Cendes, F., & Li, L. M. (2004) · Human Brain Mapping · doi:10.1002/hbm.20023 · Cited by 67
Nurse-Enhanced Memory Intervention in Heart Failure: The MEMOIR Study
Pressler, S. J., Therrien, B. A., Riley, P. L., Chou, C., Ronis, D. L., Koelling, T. M., Smith, D. G., Sullivan, B. J., Frankini, A.-M., & Giordani, B. (2011) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2011.06.650 · Cited by 68
Long-Term Retention Deficits in Two Cases of Disproportionate Retrograde Amnesia
Kapur, N., Scholey, K. A., Moore, E., Barker, S., Brice, J., Thompson, S. B. N., Shiel, A., Carn, R., Abbott, P., & Fleming, J. S. (1996) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.1996.8.5.416 · Cited by 68
Presynaptic NMDA receptor subunit immunoreactivity in GABAergic terminals in rat brain
Paquet, M., & Smith, Y. (2000) · The Journal of Comparative Neurology · doi:10.1002/1096-9861(20000724)423:2 · Cited by 95
Dose-related impairment of spatial learning by intrahippocampal scopolamine: antagonism by ondansetron, a 5-HT3 receptor antagonist
Carli, M., Luschi, R., & SAMANIN, R. (1997) · Behavioural Brain Research · doi:10.1016/s0166-4328(97)80988-6 · Cited by 71
Selective spatial memory impairment after right unilateral temporal lobectomy
Nunn, J. A., Polkey, C. E., & Morris, R. G. (1998) · Neuropsychologia · doi:10.1016/s0028-3932(98)00030-x · Cited by 68
Chronic Changes in Synaptic Responses of Entorhinal and Hippocampal Neurons After Amino-Oxyacetic Acid (AOAA)–Induced Entorhinal Cortical Neuron Loss
Scharfman, H. E., Goodman, J. H., Du, F., & Schwarcz, R. M. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.80.6.3031 · Cited by 68
Cellular, molecular, and genetic substrates underlying the impact of nicotine on learning
Gould, T. J., & Leach, P. T. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.08.004 · Cited by 72
Inactivation of JAK2/STAT3 Signaling Axis and Downregulation of M1 mAChR Cause Cognitive Impairment in klotho Mutant Mice, a Genetic Model of Aging
Park, S.-J., Shin, E., Min, S. S., An, J., Li, Z., Chung, Y. H., Jeong, J. H., Bach, J., Nah, S.-Y., Kim, W.-K., et al. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.39 · Cited by 67
Ischemia induces short‐ and long‐term remodeling of synaptic activity in the hippocampus
Crépel, V., Epsztein, J., & Ben‐Ari, Y. (2003) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2003.tb00242.x · Cited by 67
Effects of ethanol on hippocampal place-cell and interneuron activity
White, A. M., & Best, P. J. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02629-9 · Cited by 67
Prenatal protein malnutrition effects on the serotonergic system in the hippocampal formation: An immunocytochemical, ligand binding, and neurochemical study
Blatt, G. J., Chen, J., Rosene, D. L., Volicer, L., & Galler, J. R. (1994) · Brain Research Bulletin · doi:10.1016/0361-9230(94)90025-6 · Cited by 66
Memory Lost and Regained Following Bilateral Hippocampal Damage
Henke, K., Kroll, N. E. A., Behniea, H., Amaral, D. G., Miller, M. B., Rafal, R. D., & Gazzaniga, M. S. (1999) · Journal of Cognitive Neuroscience · doi:10.1162/089892999563643 · Cited by 67
Self-citation
Quantitative Evidence for Neuroanatomic and Neuropsychological Markers in Dementia of the Alzheimer's Type
Zakzanis, K. K. (1998) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.20.2.259.1174 · Cited by 67
Severe anoxia with and without concomitant brain atrophy and neuropsychological impairments
Hopkins, R. O., Gale, S. D., Johnson, S. C., Anderson, C. V., Bigler, E. D., Blatter, D. D., & Weaver, L. K. (1995) · Journal of the International Neuropsychological Society · doi:10.1017/s135561770000059x · Cited by 67
Mechanisms of Memory Consolidation and Transformation
Sekeres, M. J., Moscovitch, M., & Winocur, G. (2017) · Studies in neuroscience, psychology and behavioral economics · doi:10.1007/978-3-319-45066-7_2 · Cited by 75
Intrinsic Hippocampal Excitability Changes of Opposite Signs and Different Origins in CA1 and CA3 Pyramidal Neurons Underlie Aging-Related Cognitive Deficits
Oh, M. M., Simkin, D., & Disterhoft, J. F. (2016) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2016.00052 · Cited by 66
Effects of emotion and reward motivation on neural correlates of episodic memory encoding: a PET study.
Shigemune, Y., Abe, N., Suzuki, M., Ueno, A., Mori, E., Tashiro, M., Itoh, M., & Fujii, T. (2010) · Neurosciences research · doi:10.1016/j.neures.2010.01.003 · Cited by 64
Encoding activity in the medial temporal lobe examined with anatomically constrained fMRI analysis
Reber, P. J., Wong, E. C., & Buxton, R. B. (2002) · Hippocampus · doi:10.1002/hipo.10018 · Cited by 66
Copper Imbalance in Alzheimer’s Disease and Its Link with the Amyloid Hypothesis: Towards a Combined Clinical, Chemical, and Genetic Etiology
Squitti, R., Faller, P., Hureau, C., Granzotto, A., White, A. R., & Kepp, K. P. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201556 · Cited by 67
Gene expression parallels synaptic excitability and plasticity changes in Alzheimer’s disease
Saura, C. A., Parra‐Damas, A., & Enríquez-Barreto, L. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00318 · Cited by 65
Sensory-specific amnesia and hypoemotionality in humans and monkeys: Gateway for developing a hodology of memory
ROSS, E. (2008) · Cortex · doi:10.1016/j.cortex.2008.02.002 · Cited by 67
Transgenic animals relevant to Alzheimer’s disease
Seabrook, G. R., & Rosahl, T. W. (1999) · Neuropharmacology · doi:10.1016/s0028-3908(98)00170-1 · Cited by 63
The Contributions of Cingulate Cortex to Human Behavior
Devinsky, O., & Luciano, D. (1993) · Birkhäuser Boston eBooks · doi:10.1007/978-1-4899-6704-6_19 · Cited by 65
Entorhinal cortex of the monkey: VII. Intrinsic connections
Chrobak, J. J., & Amaral, D. G. (2006) · The Journal of Comparative Neurology · doi:10.1002/cne.21200 · Cited by 64
Self-citation
Neuroprotective effects of Nigella sativa extract on cell death in hippocampal neurons following experimental global cerebral ischemia-reperfusion injury in rats
Hobbenaghi, R., Javanbakht, J., Sadeghzadeh, S., Kheradmand, D., Abdi, F. S., Moghaddam, M. H. J., Mohammadiyan, M., Khadivar, F., & Mollaei, Y. (2013) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2013.11.019 · Cited by 64
Prenatal Neurobiological Development: Molecular Mechanisms and Anatomical Change
Monk, C. S., Webb, S. J., & Nelson, C. A. (2001) · Developmental Neuropsychology · doi:10.1207/s15326942dn1902_5 · Cited by 73
Hippocampal degeneration inducing impairment of learning in rats: model of dementia?
Ishikawa, K., Kubo, T., Shibanoki, S., Matsumoto, A., Hata, H., & Asai, S. (1997) · Behavioural Brain Research · doi:10.1016/s0166-4328(97)86043-3 · Cited by 64
Fundamentals of the septo-hippocampal system
Gray, J. A., & McNaughton, N. (2003) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198522713.003.0009 · Cited by 66
Increased Hippocampal ProBDNF Contributes to Memory Impairments in Aged Mice
Buhusi, M. C., Etheredge, C., Granholm, A., & Buhusi, C. V. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00284 · Cited by 67
Hippocampal CA2 Lewy pathology is associated with cholinergic degeneration in Parkinson’s disease with cognitive decline
Liu, A. K. L., Chau, T. W., Lim, E., Ahmed, I., Chang, R. C., Kalaitzakis, M. E., Graeber, M. B., Gentleman, S., & Pearce, R. K. B. (2019) · Acta Neuropathologica Communications · doi:10.1186/s40478-019-0717-3 · Cited by 64
Differential Sensitivity to Context in Diencephalic and Temporal Lobe Amnesia
Parkin, A. J., Leng, N. R. C., & Hunkin, N. M. (1990) · Cortex · doi:10.1016/s0010-9452(13)80087-1 · Cited by 64
Ceftriaxone Prevents and Reverses Behavioral and Neuronal Deficits in an MPTP-Induced Animal Model of Parkinson’s Disease Dementia
Hsu, C.-Y., Hung, C.-S., Chang, H.-M., Liao, W.-C., Ho, S.-C., & Ho, Y.-J. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.11.023 · Cited by 63
Exploring the neural bases of episodic and semantic memory: the role of structural and functional neuroimaging
Mayes, A. R., & Montaldi, D. (2001) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(01)00034-3 · Cited by 63
Remembering Preservation in Hippocampal Amnesia
Clark, I. A., & Maguire, E. A. (2015) · Annual Review of Psychology · doi:10.1146/annurev-psych-122414-033739 · Cited by 68
Weak and Nondiscriminative Responses to Conspecifics in the Rat Hippocampus
von Heimendahl, M., Rao, R. P., & Brecht, M. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.3812-11.2012 · Cited by 66
Self-organization of multiple spatial and context memories in the hippocampus
Stella, F., Cerasti, E., Si, B., Ježek, K., & Treves, A. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.12.002 · Cited by 70
Prenatal exposure to moderate levels of ethanol can have long-lasting effects on learning and memory in adult offspring
Sutherland, R. J., McDonald, R. J., & Savage, D. D. (2000) · Psychobiology · doi:10.3758/bf03332012 · Cited by 63
Memory for novel and familiar spatial and linguistic temporal distance information in hypoxic subjects
Hopkins, R. O., Kesner, R. P., & Goldstein, M. (1995) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617700000552 · Cited by 63
Computational Modeling of Entorhinal Cortex
Hasselmo, M. E., Fransén, E. A., Dickson, C. T., & Alonso, A. A. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06741.x · Cited by 63
Autoradiographic mapping of a selective cyclic adenosine monophosphate phosphodiesterase in rat brain with the antidepressant [3H]rolipram
Kaulen, P., Brüning, G., Schneider, H. H., Sarter, M. F., & Baumgarten, H. G. (1989) · Brain Research · doi:10.1016/0006-8993(89)91669-7 · Cited by 63
Hippocampal Physiology, Structure and Function and the Neuroscience of Schizophrenia: A Unified Account of Declarative Memory Deficits, Working Memory Deficits and Schizophrenic Symptoms
Wible, C. G. (2013) · Behavioral Sciences · doi:10.3390/bs3020298 · Cited by 69
Exploring the structure of a neuropsychological battery across healthy elders and those with questionable dementia and Alzheimer's disease.
Siedlecki, K. L., Honig, L. S., & Stern, Y. (2008) · Neuropsychology · doi:10.1037/0894-4105.22.3.400 · Cited by 62
Long-Term Spatial Cognitive Impairment after Middle Cerebral Artery Occlusion in Rats: No Involvement of the Hippocampus
Okada, M., Nakanishi, H., Tamura, A., Urae, A., Mine, K., Yamamoto, K., & Fujiwara, M. (1995) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1995.127 · Cited by 62
Long-Term Inhibition of Renin-Angiotensin System Sustains Memory Function in Aged Dahl Rats
Hirawa, N., Uehara, Y., Kawabata, Y., Numabe, A., Gomi, T., Ikeda, T., Suzuki, T., Goto, A., Toyo‐oka, T., & Omata, M. (1999) · Hypertension · doi:10.1161/01.hyp.34.3.496 · Cited by 62
Clomethiazole (Zendra®) in Acute Ischemic Stroke Basic Pharmacology and Biochemistry and Clinical Efficacy
Green, A. (1998) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(98)00024-2 · Cited by 61
Selective Effects of Nerve Growth Factor on Spatial Recent Memory as Assessed by a Delayed Nonmatching-to-Position Task in the Water Maze
Markowska, A. L., Price, D. D., & Koliatsos, V. E. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-10-03541.1996 · Cited by 62
A Model of the Roles of Essential Kinases in the Induction and Expression of Late Long-Term Potentiation
Smolen, P., Baxter, D. A., & Byrne, J. H. (2006) · Biophysical Journal · doi:10.1529/biophysj.105.072470 · Cited by 61
Cognitive impairment and persistent anxiety-related responses following bilateral common carotid artery occlusion in mice
Soares, L. M., Schiavon, A. P., Milani, H., & de Oliveira, R. M. W. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.04.010 · Cited by 63
Stroke and episodic memory disorders
Lim, C. S., & ALEXANDER, M. P. (2009) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2009.08.002 · Cited by 61
Unexpected amnesia: are there lessons to be learned from cases of amnesia following unilateral temporal lobe surgery?
Kapur, N. (2003) · Brain · doi:10.1093/brain/awg275 · Cited by 61
WAY 100635, a 5-HT1A receptor antagonist, prevents the impairment of spatial learning caused by intrahippocampal administration of scopolamine or 7-chloro-kynurenic acid
Carli, M., Bonalumi, P., & SAMANIN, R. (1997) · Brain Research · doi:10.1016/s0006-8993(97)81700-3 · Cited by 61

Authors: Zola-Morgan, S., Squire, L., & Amaral, D.
Affiliations: University of California San Diego (US)
Venue: The Journal of Neuroscience
Publisher: Society for Neuroscience
Published: 1986-10-01
Volume: 6
Issue: 10
Pages: 2950-2967
ISSN: 0270-6474 (ISSN-L)
1529-2401
DOI: 10.1523/jneurosci.06-10-02950.1986
PMC: PMC6568782
OpenAlex: W1598800837
Cited by: 1,997
References: 69
Citations by year: 2026: 10 · 2025: 12 · 2024: 50 · 2023: 19 · 2022: 25 · 2021: 23 · 2020: 58 · 2019: 30 · 2018: 39 · 2017: 52 · 2016: 36 · 2015: 52 · 2014: 56 · 2013: 51 · 2012: 58
FWCI: 25.73
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-sa
creativecommons.org/licenses/by-nc-sa/4.0/ (vor, 182 d)
Locations: Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
National Institute of Mental Health (MH24600)
National Institute of Neurological Disorders and Stroke (NS 20004, NS19063)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
Keywords: anterograde amnesia, hippocampal CA1, bilateral hippocampal lesions, memory impairment, ischemic stroke, medial temporal lobe, retrograde amnesia, neuropathology, neuropsychological assessment
MeSH terms: Amnesia, Cerebral Cortex, Brain Ischemia, Diencephalon, Hippocampus, Humans, Male, Memory Disorders, Middle Aged, Temporal Lobe

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks