Cited by 1,997Memory and Neural MechanismsMemory Processes and InfluencesCognitive Functions and Memory

The DOI matches its Crossref record, with a small difference in title or year; 69 of the 69 references it cites were found in a registry or an index.

Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus

Open access

Zola-Morgan, S, Squire, LR, Amaral, DG·1986·The Journal of Neuroscience

DOI 10.1523/jneurosci.06-10-02950.1986PMC PMC6568782

Open this paper in CoChat — free account

Abstract

During the past 100 years clinical studies of amnesia have linked memory impairment to damage of the hippocampus. Yet the damage in these cases has not usually been confined to the hippocampus, and the status of memory functions has often been based on incomplete neuropsychological information. Thus, the human cases have until now left some uncertainty as to whether lesions limited to the hippocampus are sufficient to cause amnesia. Here we report a case of amnesia in a patient (R.B.) who developed memory impairment following an ischemic episode. During the 5 years until his death, R.B. exhibited marked anterograde amnesia, little if any retrograde amnesia, and showed no signs of cognitive impairment other than memory. Thorough histological examination revealed a circumscribed bilateral lesion involving the entire CA1 field of the hippocampus. Minor pathology was found elsewhere in the brain (e.g., left globus pallidus, right postcentral gyrus, left internal capsule), but the only damage that could be reasonably associated with the memory defect was the lesion in the hippocampus. To our knowledge, this is the first reported case of amnesia following a lesion limited to the hippocampus in which extensive neuropsychological and neuropathological analyses have been carried out.

Integrity signals

Registry

Crossref · 10.1523/jneurosci.06-10-02950.1986

Cites

69 of 69 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

LOSS OF RECENT MEMORY AFTER BILATERAL HIPPOCAMPAL LESIONS
Scoville, W. B., & Milner, B. (1957) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.20.1.11 · Cited by 7,322
Le test de copie d'une figure complexe
Osterrieth, P. M. (1944) · Medical Entomology and Zoology · Cited by 2,336
Hippocampus, space, and memory
Olton, D. S., Becker, J. T., & Handelmann, G. E. (1979) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00062713 · Cited by 2,018
Studies on the structure of the cerebral cortex. II. Continuation of the study of the ammonic system.
de Nó, R. L. (1934) · Cited by 1,974
A new model of bilateral hemispheric ischemia in the unanesthetized rat.
Pulsinelli, W. A., & Brierley, J. B. (1979) · Stroke · doi:10.1161/01.str.10.3.267 · Cited by 1,947
Cell Damage in the Brain: A Speculative Synthesis
Siesjö, B. K. (1981) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1981.18 · Cited by 1,807
EPILEPSY AND THE TEMPORAL LOBES
Margerison, J. H., & Corsellis, J. (1966) · Brain · doi:10.1093/brain/89.3.499 · Cited by 1,260
The information that amnesic patients do not forget.
Graf, P., Squire, L. R., & Mandler, G. (1984) · Journal of Experimental Psychology Learning Memory and Cognition · doi:10.1037//0278-7393.10.1.164 · Cited by 883
Self-citation
Disorders of Learning and Memory after Temporal Lobe Lesions in Man
Milner, B. A. (1972) · Neurosurgery · doi:10.1093/neurosurgery/19.cn_suppl_1.421 · Cited by 882
THE WERNICKE-KORSAKOFF SYNDROME
Russell, R. W. R. (1972) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.35.2.277 · Cited by 815

Show all 69 references

Sorted by citations

Items 101–200 of 1,006

Topographically specific hippocampal projections target functionally distinct prefrontal areas in the rhesus monkey
Barbas, H., & Blatt, G. J. (1995) · Hippocampus · doi:10.1002/hipo.450050604 · Cited by 464
A contextual binding theory of episodic memory: systems consolidation reconsidered
Yonelinas, A. P., Ranganath, C., Ekstrom, A. D., & Wiltgen, B. J. (2019) · Nature reviews. Neuroscience · doi:10.1038/s41583-019-0150-4 · Cited by 492
H. M.’s Medial Temporal Lobe Lesion: Findings from Magnetic Resonance Imaging
Corkin, S., Amaral, D. G., González, R., Johnson, K. A., & Hyman, B. T. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-10-03964.1997 · Cited by 451
Self-citation
The effects of acute stress on episodic memory: A meta-analysis and integrative review.
Shields, G. S., Sazma, M. A., McCullough, A. M., & Yonelinas, A. P. (2017) · Psychological Bulletin · doi:10.1037/bul0000100 · Cited by 450
Disorders of memory
Kopelman, M. D. (2002) · Brain · doi:10.1093/brain/awf229 · Cited by 457
Inferior Temporal Cortex: Where Visual Perception Meets Memory
Miyashita, Y. (1993) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.16.030193.001333 · Cited by 452
The case of K.C.: contributions of a memory-impaired person to memory theory
Rosenbaum, R. S., Köhler, S., Schacter, D. L., Moscovitch, M., Westmacott, R., Black, S. E., Gao, F., & Tulving, E. (2005) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2004.10.007 · Cited by 433
Specific Hippocampal Volume Reductions in Individuals at Risk for Alzheimer’s Disease
Convit, A., De Leon, M. J., Tarshish, C., De Santi, S., Tsui, W., Rusinek, H., & George, A. (1997) · Neurobiology of Aging · doi:10.1016/s0197-4580(97)00001-8 · Cited by 427
Delayed and prolonged post-ischemic hypothermia is neuroprotective in the gerbil
Colbourne, F., & Corbett, D. (1994) · Brain Research · doi:10.1016/0006-8993(94)90488-x · Cited by 418
Human recognition memory: a cognitive neuroscience perspective
Rugg, M. D., & Yonelinas, A. P. (2003) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(03)00131-1 · Cited by 417
Memory: brain systems and behavior
Squire, L. R., & Zola-Morgan, S. M. (1988) · Trends in Neurosciences · doi:10.1016/0166-2236(88)90144-0 · Cited by 416
Self-citation
Movement of zinc and its functional significance in the brain
Takeda, A. (2000) · Brain Research Reviews · doi:10.1016/s0165-0173(00)00044-8 · Cited by 422
Extrinsic projections from area CA 1 of the rat hippocampus: Olfactory, cortical, subcortical, and bilateral hippocampal formation projections
van Groen, T., & Wyss, J. M. (1990) · The Journal of Comparative Neurology · doi:10.1002/cne.903020308 · Cited by 415
Limbic hypometabolism in Alzheimer's disease and mild cognitive impairment
Nestor, P. J., Fryer, T. D., Smielewski, P. S., & Hodges, J. R. (2003) · Annals of Neurology · doi:10.1002/ana.10669 · Cited by 429
Prolonged memory impairment in the absence of hippocampal cell death following traumatic brain injury in the rat
Lyeth, B. G., Jenkins, L. W., Hamm, R. J., Dixon, C. E., Phillips, L. L., Clifton, G. L., Young, H. F., & Hayes, R. L. (1990) · Brain Research · doi:10.1016/0006-8993(90)91229-a · Cited by 418
Dissociating prefrontal and hippocampal function in episodic memory encoding
Dolan, R. J., & Fletcher, P. C. (1997) · Nature · doi:10.1038/41561 · Cited by 410
Trace Eyeblink Conditioning Increases CA1 Excitability in a Transient and Learning-Specific Manner
Moyer, J. R., Thompson, L. T., & Disterhoft, J. F. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-17-05536.1996 · Cited by 403
Differentiating the roles of the hippocampus complex and the neocortex in long-term memory storage: Evidence from the study of semantic dementia and Alzheimer's disease.
Graham, K. S., & Hodges, J. R. (1997) · Neuropsychology · doi:10.1037/0894-4105.11.1.77 · Cited by 421
Brainstem, cerebellar and limbic neuroanatomical abnormalities in autism
Courchesne, E. (1997) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(97)80016-5 · Cited by 401
Differential remoteness and emotional tone modulate the neural correlates of autobiographical memory
Piefke, M. (2003) · Brain · doi:10.1093/brain/awg064 · Cited by 391
Improved memory functioning and frontal lobe maturation between childhood and adolescence: A structural MRI study
SOWELL, E. R., DELIS, D., STILES, J., & JERNIGAN, T. L. (2001) · Journal of the International Neuropsychological Society · doi:10.1017/s135561770173305x · Cited by 388
Configural association theory and the hippocampal formation: An appraisal and reconfiguration
Rudy, J. W., & Sutherland, R. J. (1995) · Hippocampus · doi:10.1002/hipo.450050502 · Cited by 383
Neurophysiological Manifestations of Recollective Experience during Recognition Memory Judgments
Smith, M. E. (1993) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.1993.5.1.1 · Cited by 383
Topographical organization of the entorhinal projection to the dentate gyrus of the monkey
Witter, M., Hoesen, G. W. V., & Amaral, D. (1989) · Journal of Neuroscience · doi:10.1523/jneurosci.09-01-00216.1989 · Cited by 380
Self-citation
Cellular Imaging ofzif268Expression in the Hippocampus and Amygdala during Contextual and Cued Fear Memory Retrieval: Selective Activation of Hippocampal CA1 Neurons during the Recall of Contextual Memories
Hall, J., Thomas, K. L., & Everitt, B. J. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-06-02186.2001 · Cited by 398
Macaque monkey retrosplenial cortex: II. Cortical afferents
Kobayashi, Y., & Amaral, D. G. (2003) · The Journal of Comparative Neurology · doi:10.1002/cne.10883 · Cited by 387
Self-citation
Damage limited to the hippocampal region produces long-lasting memory impairment in monkeys
Alvarez, P., Zola-Morgan, S. M., & Squire, L. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-05-03796.1995 · Cited by 376
Self-citation
Differential Regulation of NMDAR1 mRNA and Protein by Estradiol in the Rat Hippocampus
Gazzaley, A. H., Weiland, N. G., McEwen, B. S., & Morrison, J. H. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-21-06830.1996 · Cited by 375
The hippocampal formation is necessary for rats to learn and remember configural discriminations
Rudy, J. W., & Sutherland, R. J. (1989) · Behavioural Brain Research · doi:10.1016/s0166-4328(89)80093-2 · Cited by 383
The impact of emotion on perception, attention, memory, and decision-making
Brosch, T., Scherer, K. R., Grandjean, D., & Sander, D. (2013) · Swiss Medical Weekly · doi:10.4414/smw.2013.13786 · Cited by 446
Temporal Lobe Regions on Magnetic Resonance Imaging Identify Patients With Early Alzheimer's Disease
Killiany, R., Moss, M. B., Albert, M., Sándor, T., Tieman, J., & Jolesz, F. A. (1993) · Archives of Neurology · doi:10.1001/archneur.1993.00540090052010 · Cited by 371
DECLARATIVE MEMORY: Insights from Cognitive Neurobiology
Eichenbaum, H. (1997) · Annual Review of Psychology · doi:10.1146/annurev.psych.48.1.547 · Cited by 383
Declarative memory impairments in Alzheimer's disease and semantic dementia
Nestor, P. J., Fryer, T. D., & Hodges, J. R. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2005.10.008 · Cited by 370
Beyond the Cognitive Map: From Place Cells to Episodic Memory
Redish, A. D. (1999) · Cited by 369
Virtual navigation in humans: the impact of age, sex, and hormones on place learning
Driscoll, I. F., Hamilton, D. A., Yeo, R. A., Brooks, W. M., & Sutherland, R. J. (2005) · Hormones and Behavior · doi:10.1016/j.yhbeh.2004.11.013 · Cited by 394
The limbic lobe and its output channels: implications for emotional functions and adaptive behavior
Heimer, L., & Van Hoesen, G. W. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.06.006 · Cited by 366
Can disturbed brain microcirculation cause Alzheimer’s disease?
de la Torre, J. C., & Mussivan, T. (1993) · Neurological Research · doi:10.1080/01616412.1993.11740127 · Cited by 364
Severity of memory impairment in monkeys as a function of locus and extent of damage within the medial temporal lobe memory system
Zola‐Morgan, S., Squire, L. R., & Ramus, S. J. (1994) · Hippocampus · doi:10.1002/hipo.450040410 · Cited by 362
Self-citation
Mild Experimental Brain Injury in the Rat Induces Cognitive Deficits Associated with Regional Neuronal Loss in the Hippocampus
Hicks, R. R., Smith, D. H., Lowenstein, D. H., Marie, R. L. S., & McIntosh, T. K. (1993) · Journal of Neurotrauma · doi:10.1089/neu.1993.10.405 · Cited by 359
The Korsakoff Syndrome
Kopelman, M. D. (1995) · The British Journal of Psychiatry · doi:10.1192/bjp.166.2.154 · Cited by 351
Inhibition of proteolysis protects hippocampal neurons from ischemia.
Lee, K. S., Frank, S., Vanderklish, P. W., Arai, A., & LYNCH, G. S. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.16.7233 · Cited by 354
Perspectives on object-recognition memory following hippocampal damage: lessons from studies in rats
Mumby, D. G. (2001) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00367-9 · Cited by 356
Sleep states and memory processes in humans: procedural versus declarative memory systems
Smith, C. (2001) · Sleep Medicine Reviews · doi:10.1053/smrv.2001.0164 · Cited by 355
Developmental amnesia associated with early hypoxic-ischaemic injury
Gadian, D. G. (2000) · Brain · doi:10.1093/brain/123.3.499 · Cited by 355
Activation of medial temporal structures during episodic memory retrieval
Nyberg, L. H., McLntosh, A. R., Houle, S., Nilsson, L.-G., & Tulving, E. (1996) · Nature · doi:10.1038/380715a0 · Cited by 356
Semantic Memory and the Human Hippocampus
Manns, J. R., Hopkins, R. O., & Squire, L. R. (2003) · Neuron · doi:10.1016/s0896-6273(03)00146-6 · Cited by 354
Self-citation
The hippocampus and mechanisms of declarative memory
Eichenbaum, H. (1999) · Behavioural Brain Research · doi:10.1016/s0166-4328(99)00044-3 · Cited by 353
Anterograde and retrograde amnesia in rats with dorsal hippocampal or dorsomedial thalamic lesions
Winocur, G. (1990) · Behavioural Brain Research · doi:10.1016/0166-4328(90)90012-4 · Cited by 352
The role of the fornix/fimbria and some related subcortical structures in place learning and memory
Sutherland, R. J., & Rodríguez, A. J. (1989) · Behavioural Brain Research · doi:10.1016/s0166-4328(89)80059-2 · Cited by 355
Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates
Yamashima, T. (2000) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00006-x · Cited by 346
What happened? Alcohol, memory blackouts, and the brain.
White, A. M. (2003) · Europe PMC (PubMed Central) · Cited by 351
Real-Time Tracking of Memory Formation in the Human Rhinal Cortex and Hippocampus
Fernández, G., Effern, A., Grünwald, T., Pezer, N., Lehnertz, K., Dümpelmann, M., Roost, D. V., & Elger, C. E. (1999) · Science · doi:10.1126/science.285.5433.1582 · Cited by 340
Evaluation of Memory Dysfunction Following Experimental Brain Injury Using the Morris Water Maze
Smith, D. H., Okiyama, K., Thomas, M. J., CLAUSSEN, B., & McINTOSH, T. K. (1991) · Journal of Neurotrauma · doi:10.1089/neu.1991.8.259 · Cited by 351
Environmental Enrichment Modifies the PKA-Dependence of Hippocampal LTP and Improves Hippocampus-Dependent MemoryPreprint
Duffy, S. N., Craddock, K. J., Abel, T. G., & Nguyen, P. (2001) · Learning & Memory · doi:10.1101/lm.36301 · Cited by 349
The longer-term impacts of Western diet on human cognition and the brain
Francis, H., & Stevenson, R. J. (2013) · Appetite · doi:10.1016/j.appet.2012.12.018 · Cited by 368
Anatomical evidence for direct projections from the entorhinal area to the entire cortical mantle in the rat
Swanson, L. W., & Köhler, C. (1986) · Journal of Neuroscience · doi:10.1523/jneurosci.06-10-03010.1986 · Cited by 340
The effects of visual stimulation and memory on neurons of the hippocampal formation and the neighboring parahippocampal gyrus and inferior temporal cortex of the primate
Riches, I. P., Wilson, F., & Mw, B. (1991) · Journal of Neuroscience · doi:10.1523/jneurosci.11-06-01763.1991 · Cited by 336
Free recall and recognition in a network model of the hippocampus: simulating effects of scopolamine on human memory function
Hasselmo, M. E., & Wyble, B. (1997) · Behavioural Brain Research · doi:10.1016/s0166-4328(97)00048-x · Cited by 338
Segregating the functions of human hippocampus
Strange, B. A., Fletcher, P. C., Henson, R. N., Friston, K. J., & Dolan, R. J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.7.4034 · Cited by 334
Enduring memory impairment in monkeys after ischemic damage to the hippocampus
Zola-Morgan, S. M., Squire, L., Rempel-Clower, N., Clower, R., & Amaral, D. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-07-02582.1992 · Cited by 331
Self-citation
Regulation of hippocampal synaptic plasticity by cyclic AMP-dependent protein kinases
Nguyen, P., & Woo, N. H. (2003) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2003.12.003 · Cited by 333
The slow forgetting of emotional episodic memories: an emotional binding account
Yonelinas, A. P., & Ritchey, M. (2015) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2015.02.009 · Cited by 341
Hippocampal Atrophy in Normal Aging
Golomb, J. B. (1993) · Archives of Neurology · doi:10.1001/archneur.1993.00540090066012 · Cited by 323
Amnesia and recognition memory: A re-analysis of psychometric data
Aggleton, J. P., & Shaw, C. (1996) · Neuropsychologia · doi:10.1016/0028-3932(95)00150-6 · Cited by 328
Hierarchical organization of cognitive memory
Mishkin, M., SUZUKI, W. A., Gadian, D. G., & Vargha‐Khadem, F. (1997) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.1997.0132 · Cited by 323
The radiologic prediction of Alzheimer disease: the atrophic hippocampal formation.
de Leon, M. J., Golomb, J. B., GEORGE, A. E., Convit, A. J., Tarshish, C. Y., McRae, T., Santi, S. D., Smith, G. S., Ferris, S. H., & Noz, M. E. (1993) · PubMed Central · Cited by 322
Place cells, navigational accuracy, and the human hippocampus
O'Keefe, J. M., Burgess, N., Donnett, J. G., Jeffery, K. J., & Maguire, E. A. (1998) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.1998.0287 · Cited by 314
The Neuropsychology of Memory: Parallel Findings in Humans and Nonhuman Primatesa
ZOLA‐MORGAN, S., & SQUIRE, L. R. (1990) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1990.tb48905.x · Cited by 318
Self-citation
Hippocampal markers of age-related memory dysfunction: Behavioral, electrophysiological and morphological perspectives
Geinisman, Y., deToledo‐Morrell, L., Morrell, F., & Heller, R. E. (1995) · Progress in Neurobiology · doi:10.1016/0301-0082(94)00047-l · Cited by 327
Perirhinal and parahippocampal cortices of the macaque monkey: Projections to the neocortex
Lavenex, P., SUZUKI, W. A., & Amaral, D. G. (2002) · The Journal of Comparative Neurology · doi:10.1002/cne.10243 · Cited by 317
Self-citation
A Dissociation of Encoding and Retrieval Processes in the Human Hippocampus
Eldridge, L. L., Engel, S. A., Zeineh, M., Bookheimer, S. Y., & Knowlton, B. J. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.3420-04.2005 · Cited by 315
Magnetic resonance imaging of the hippocampal formation and mammillary nuclei distinguish medial temporal lobe and diencephalic amnesia
Squire, L., Amaral, D., & Press, G. A. (1990) · Journal of Neuroscience · doi:10.1523/jneurosci.10-09-03106.1990 · Cited by 315
Self-citation
Neuropsychological Functioning Associated with High-Altitude Exposure
Ortega, J. V., Buela‐Casal, G., Garrido, E., & Navarrete, B. A. (2004) · Neuropsychology Review · doi:10.1007/s11065-004-8159-4 · Cited by 314
Cognition impairment in the genetic model of aging klotho gene mutant mice: a role of oxidative stress
Nagai, T., Yamada, K., Kim, H., Kim, Y., Noda, Y., Imura, A., Nabeshima, Y., & Nabeshima, T. (2002) · The FASEB Journal · doi:10.1096/fj.02-0448fje · Cited by 318
Hippocampal volume in normal aging and traumatic brain injury.
Bigler, E. D., Blatter, D. D., Anderson, C. V., Johnson, S. C., Gale, S. D., Hopkins, R. O., & Burnett, B. (1997) · PubMed Central · Cited by 311
The neuroscience of remote memory
Squire, L. R., & Bayley, P. J. (2007) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2007.02.006 · Cited by 329
Self-citation
Amygdalohippocampal MR volume measurements in the early stages of Alzheimer disease.
Lehéricy, S., Baulac, M., Jacques Chiras, C., Pierot, L., Martin-Duverneuil, N., Pillon, B., Deweer, B., Dubois, B., & Marsault, C. (1994) · PubMed Central · Cited by 308
Hippocampal Formation
Amaral, D. G., & Insausti, R. (1990) · Elsevier eBooks · doi:10.1016/b978-0-12-547625-6.50026-x · Cited by 300
Self-citation
Perinatal Iron Deficiency Decreases Cytochrome c Oxidase (CytOx) Activity in Selected Regions of Neonatal Rat Brain
de Ungria, M., Rao, R., Wobken, J. D., Luciana, M. M., Nelson, C. A., & Georgieff, M. (2000) · Pediatric Research · doi:10.1203/00006450-200008000-00009 · Cited by 300
Lesions of the amygdala that spare adjacent cortical regions do not impair memory or exacerbate the impairment following lesions of the hippocampal formation
Zola-Morgan, S. M., Squire, L., & Amaral, D. (1989) · Journal of Neuroscience · doi:10.1523/jneurosci.09-06-01922.1989 · Cited by 302
Self-citation
Remote spatial memory in an amnesic person with extensive bilateral hippocampal lesions
Rosenbaum, R. S., Priselac, S., Köhler, S., Black, S. E., Gao, F., Nadel, L., & Moscovitch, M. (2000) · Nature Neuroscience · doi:10.1038/79867 · Cited by 293
The Hippocampus in Depression: More Than the Sum of Its Parts? Advanced Hippocampal Substructure Segmentation in Depression
Roddy, D. W., Farrell, C., Doolin, K., Roman, E., Tozzi, L., Frodl, T., O’Keane, V., & O’Hanlon, E. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2018.08.021 · Cited by 287
Human hippocampus and viewpoint dependence in spatial memory
King, J. A., Burgess, N., Hartley, T., Vargha‐Khadem, F., & O'Keefe, J. M. (2002) · Hippocampus · doi:10.1002/hipo.10070 · Cited by 284
Transient Inactivation of Perirhinal Cortex Disrupts Encoding, Retrieval, and Consolidation of Object Recognition Memory
Winters, B. D., & Bussey, T. J. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.3827-04.2005 · Cited by 294
Quantal analysis and synaptic anatomy--integrating two views of hippocampal plasticity.
Lisman, J., & Harris, K. (1993) · Trends in Neurosciences · doi:10.1016/0166-2236(93)90122-3 · Cited by 271
The human entorhinal cortex: A cytoarchitectonic analysis
Insausti, R., Tuñón, T., Sobreviela, T., Serrano, A. M. I., & Gonzalo, L. M. (1995) · The Journal of Comparative Neurology · doi:10.1002/cne.903550203 · Cited by 275
Hippocampal abnormalities in amnesic patients revealed by high-resolution magnetic resonance imaging
Press, G. A., Amaral, D. G., & Squire, L. R. (1989) · Nature · doi:10.1038/341054a0 · Cited by 281
Self-citation
Learning and retention of words and designs following excision from medial or lateral temporal-lobe structures
Jones‐Gotman, M. (1997) · Neuropsychologia · doi:10.1016/s0028-3932(97)00024-9 · Cited by 279
Hippocampus, amygdala, and memory deficits in rats
Sutherland, R. J., & McDonald, R. J. (1990) · Behavioural Brain Research · doi:10.1016/0166-4328(90)90072-m · Cited by 283
The problem of assessing effective neuroprotection in experimental cerebral ischemia
Corbett, D. (1998) · Progress in Neurobiology · doi:10.1016/s0301-0082(97)00078-6 · Cited by 275
Increased vulnerability of the midly traumatized rat brain to cerebral ischemia: the use of controlled secondary ischemia as a research tool to identify common or different mechanisms contributing to mechanical and ischemic brain injury
Jenkins, L. W., Moszyński, K., Lyeth, B. G., Lewelt, W., DeWitt, D. S., Allen, A. M., Dixon, C. E., Povlishock, J. T., Majewski, T. J., Clifton, G. L., et al. (1989) · Brain Research · doi:10.1016/0006-8993(89)91409-1 · Cited by 276
Human amnesia and animal models of amnesia: Performance of amnesic patients on tests designed for the monkey.
Squire, L. R., Zola-Morgan, S. M., & Chen, K. S. (1988) · Behavioral Neuroscience · doi:10.1037//0735-7044.102.2.210 · Cited by 276
Self-citation
MK-801 is neuroprotective in gerbils when administered during the post-ischaemic period
Gill, R., Foster, A. C., & Woodruff, G. N. (1988) · Neuroscience · doi:10.1016/0306-4522(88)90040-1 · Cited by 274
Hippocampal Function and Spatial Memory: Evidence From Functional Neuroimaging in Healthy Participants and Performance of Patients With Medial Temporal Lobe Resections.
Bohbot, V. D., Iaria, G., & Petrides, M. (2004) · Neuropsychology · doi:10.1037/0894-4105.18.3.418 · Cited by 296
A Macromolecular Synthesis-Dependent Late Phase of Long-Term Potentiation Requiring cAMP in the Medial Perforant Pathway of Rat Hippocampal Slices
Nguyen, P., & Kandel, E. R. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-10-03189.1996 · Cited by 272
Impaired recognition memory in patients with lesions limited to the hippocampal formation.
Reed, J. M., & Squire, L. R. (1997) · Behavioral Neuroscience · doi:10.1037//0735-7044.111.4.667 · Cited by 295
Self-citation
Untitled work
(2000) · doi:10.1002/(sici)1099-1573(200005)14:3
Defining a Molecular Atlas of the Hippocampus Using DNA Microarrays and High-Throughput In Situ Hybridization
Lein, E. S., Zhao, X., & Gage, F. H. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4710-03.2004 · Cited by 270
Lesions of the hippocampal formation but not lesions of the fornix or the mammillary nuclei produce long-lasting memory impairment in monkeys
Zola-Morgan, S. M., Squire, L., & Amaral, D. (1989) · Journal of Neuroscience · doi:10.1523/jneurosci.09-03-00898.1989 · Cited by 273
Self-citation
Postischemic hypothermia
Colbourne, F., Sutherland, G. R., & Corbett, D. (1997) · Molecular Neurobiology · doi:10.1007/bf02740655 · Cited by 268

Authors: Zola-Morgan, S., Squire, L., & Amaral, D.
Affiliations: University of California San Diego (US)
Venue: The Journal of Neuroscience
Publisher: Society for Neuroscience
Published: 1986-10-01
Volume: 6
Issue: 10
Pages: 2950-2967
ISSN: 0270-6474 (ISSN-L)
1529-2401
DOI: 10.1523/jneurosci.06-10-02950.1986
PMC: PMC6568782
OpenAlex: W1598800837
Cited by: 1,997
References: 69
Citations by year: 2026: 10 · 2025: 12 · 2024: 50 · 2023: 19 · 2022: 25 · 2021: 23 · 2020: 58 · 2019: 30 · 2018: 39 · 2017: 52 · 2016: 36 · 2015: 52 · 2014: 56 · 2013: 51 · 2012: 58
FWCI: 25.73
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-sa
creativecommons.org/licenses/by-nc-sa/4.0/ (vor, 182 d)
Locations: Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
National Institute of Mental Health (MH24600)
National Institute of Neurological Disorders and Stroke (NS 20004, NS19063)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
Keywords: anterograde amnesia, hippocampal CA1, bilateral hippocampal lesions, memory impairment, ischemic stroke, medial temporal lobe, retrograde amnesia, neuropathology, neuropsychological assessment
MeSH terms: Amnesia, Cerebral Cortex, Brain Ischemia, Diencephalon, Hippocampus, Humans, Male, Memory Disorders, Middle Aged, Temporal Lobe

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks