The DOI matches its Crossref record; 57 of the 58 references it cites were found in a registry or an index.
Individual Differences in Amygdala Activity Predict Response Speed during Working Memory
Open accessAbstract
The human amygdala has classically been viewed as a brain structure primarily related to emotions and dissociated from higher cognition. We report here findings suggesting that the human amygdala also has a role in supporting working memory (WM), a canonical higher cognitive function. In a first functional magnetic resonance imaging (fMRI) study (n= 53), individual differences in amygdala activity predicted behavioral performance in a 3-back WM task. Specifically, higher event-related amygdala amplitude predicted faster response time (RT;r= −0.64), with no loss of accuracy. This relationship was not contingent on mood state, task content, or personality variables. In a second fMRI study (n= 21), we replicated the key finding (r= −0.47) and further showed that the correlation between the amygdala and faster RT was specific to a high working memory load condition (3-back) compared with a low working memory load condition (1-back). These results support models of amygdala function that can account for its involvement not only in emotion but also higher cognition.
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“These regions have been implicated in performance on the N‐Back previously (Dahlin, Neely, Larsson, Bäckman, & Nyberg, 2008; Kubat‐Silman, Dagenbach, & Absher, 2002; Schaefer et al., 2006; Takeuchi et al., 2010; Zou, Hong, Wang, Gao, & Yang, 2011).”
From Brain structure, working memory and response inhibition in childhood leukemia survivors (2017) · cites this paper as Schaefer et al., 2006
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Statistical parametric maps in functional imaging: A general linear approach
Friston, K. J., Holmes, A. P., Worsley, K. J., Poline, J. ‐., Frith, C. D., & Frackowiak, R. S. J. (1994) · Human Brain Mapping · doi:10.1002/hbm.460020402 · Cited by 9,688
Carver, C. S., & White, T. L. (1994) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.67.2.319 · Cited by 7,306
Anderson, J. R. (2013) · doi:10.4324/9781315799438 · Cited by 6,761
Talairach, J., Tournoux, P., & Rayport, M. (1988) · Thieme eBooks · Cited by 5,058
The Emotional Brain: The Mysterious Underpinnings of Emotional Life
LeDoux, J. E. (2004) · Medical Entomology and Zoology · Cited by 4,212
(1998) · Cited by 4,172
N-back working memory paradigm: a meta-analysis of normative functional neuroimaging studies.
Owen, A. M., McMillan, K. M., Laird, A. R., & Bullmore, E. (2005) · Human Brain Mapping · doi:10.1002/hbm.20131 · Cited by 3,560
Pragmatics of measuring recognition memory: Applications to dementia and amnesia.
Snodgrass, J. G., & Corwin, J. (1988) · Journal of Experimental Psychology General · doi:10.1037//0096-3445.117.1.34 · Cited by 3,093
Gusnard, D. A., Akbudak, E., Shulman, G. L., & Raichle, M. E. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.071043098 · Cited by 2,997
The amygdala: vigilance and emotion
Davis, M., & Whalen, P. J. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4000812 · Cited by 2,882
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Research works printed but not linked: 5
- 10.1037//0022-3514.67.2.319 · DOI · Paper page
- Frijda NH (1986) The emotions (Cambridge UP, London).
- 10.1037/0096-3445.130.3.436 · DOI
- 10.1037//1082-989X.1.2.178 · DOI
- 10.1037/0096-3445.117.1.34 · DOI
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Ou, Y., Chen, Z., Wang, Y., Li, H., Liu, F., Li, P., Lv, D., Liu, Y., Lang, B., Zhao, J., et al. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-06747-x
Wang, J., Cao, Y., Guo, Y., Yu, P., Zhu, Y., Wang, Y., & Song, Y. (2025) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2025.180353
PASAT performance improves across adolescence in a sex-specific manner
Waldman, J. S. (2013) · CommonKnowledge Research Repository (Pacific University Oregon)
Louragli, I., Fath, N., Bouazza, G., Oubal, R., & Harchaoui, H. (2025) · BIO Web of Conferences · doi:10.1051/bioconf/202520001006
Lee, H.-T., Cho, E.-B., Jun, S., Kim, J.-S., Chung, C. K., & Hwang, H. (2026) · Research Square · doi:10.21203/rs.3.rs-10624621/v1
Metadata
- Authors
- Schaefer, A., Braver, T. S., Reynolds, J. R., Burgess, G. C., Yarkoni, T., & Gray, J. R.
- Affiliations
- Yale University (US)
- Washington University in St. Louis (US)
- University of Leeds (GB)
- University of Colorado Boulder (US)
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2006-10-04
- Volume
- 26
- Issue
- 40
- Pages
- 10120-10128
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC1851922
- OpenAlex
- W1990528118
- Cited by
- 106
- References
- 58
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 8 · 2022: 3 · 2021: 3 · 2020: 6 · 2019: 8 · 2018: 6 · 2017: 5 · 2016: 2 · 2015: 3 · 2014: 9 · 2013: 6 · 2012: 7
- FWCI
- 2.91
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of Mental Health (R01MH066088, MH66088)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
- Keywords
- amygdala, working memory, individual differences, response speed, event-related potentials, 3-back task, working memory load, cognitive function, emotion and cognition
- MeSH terms
- Adolescent, Adult, Amygdala, Female, Humans, Individuality, Male, Memory, Photic Stimulation, Predictive Value of Tests, Psychomotor Performance, Reaction Time, Regression Analysis, Linear Models
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