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The Mammalian Golgi Regulates Numb Signaling in Asymmetric Cell Division by Releasing ACBD3 during Mitosis

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Dscam Mediates Remodeling of Glutamate Receptors in Aplysia during De Novo and Learning-Related Synapse Formation

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NMDA-Mediated Regulation of DSCAM Dendritic Local Translation Is Lost in a Mouse Model of Down's Syndrome

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Drosophila Dscam Proteins Regulate Postsynaptic Specificity at Multiple-Contact Synapses

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The Down Syndrome Critical Region Regulates Retinogeniculate Refinement

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Down syndrome critical region around D21S55 on proximal 21q22.3

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Dscam mutation leads to hydrocephalus and decreased motor function

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DSCAM Promotes Refinement in the Mouse Retina through Cell Death and Restriction of Exploring Dendrites

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Synaptic actin stabilization protein loss in Down syndrome and Alzheimer disease

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DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors

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DSCAM and DSCAML1 regulate the radial migration and callosal projection in developing cerebral cortex.

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p39 Is Responsible for Increasing Cdk5 Activity during Postnatal Neuron Differentiation and Governs Neuronal Network Formation and Epileptic Responses

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DSCAM regulates delamination of neurons in the developing midbrain

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Chronic treatment with a MEK inhibitor reverses enhanced excitatory field potentials in Syngap1+/− mice

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Motor hypertonia and lack of locomotor coordination in mutant mice lacking DSCAM

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Critical periods and Autism Spectrum Disorders, a role for sleep

Medina, E., Peterson, S., Ford, K., Singletary, K. G., & Peixoto, L. (2022) · Neurobiology of Sleep and Circadian Rhythms · doi:10.1016/j.nbscr.2022.100088 · Cited by 15 · see citing works

Defects in neural guidepost structures and failure to remove leptomeningeal cells from the septal midline behind the interhemispheric fusion defects in Netrin1 deficient mice

Hakanen, J., & Salminen, M. (2015) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2015.08.005 · Cited by 12 · see citing works

DSCAM Mutation Impairs Motor Cortex Network Dynamic and Voluntary Motor Functions

Laflamme, O. D., Lemieux, M., Thiry, L., & Bretzner, F. (2018) · Cerebral Cortex · doi:10.1093/cercor/bhy097 · Cited by 12 · see citing works

Animal models of autism: a perspective from autophagy mechanisms

Dana, H., Tahtasakal, R., & Şener, E. F. (2020) · Journal of Translational Genetics and Genomics · doi:10.20517/jtgg.2020.25 · Cited by 12 · see citing works

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Viard, J., Loe-Mie, Y., Daudin, R., Khelfaoui, M., Plançon, C., Boland, A., Tejedor, F. J., Huganir, R. L., Kim, E., Kinoshita, M., et al. (2022) · Life Science Alliance · doi:10.26508/lsa.202101205 · Cited by 11 · see citing works

Neurobehavioral Disorders and Developmental Origins of Health and Disease

Sandman, C. A., Class, Q. A., Glynn, L. M., & Davis, E. P. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-801383-0.00013-x · Cited by 11 · see citing works

Local translation of the Down syndrome cell adhesion molecule ( DSCAM ) mRNA in the vertebrate central nervous system

Montesinos, M. L. (2017) · Journal of Neurogenetics · doi:10.1080/01677063.2017.1391250 · Cited by 11 · see citing works

Neuronal DSCAM regulates the peri-synaptic localization of GLAST in Bergmann glia for functional synapse formation

Dewa, K., Arimura, N., Kakegawa, W., Itoh, M., Adachi, T., Miyashita, S., Inoue, Y., Hizawa, K., Hori, K., Honjoya, N., et al. (2024) · Nature Communications · doi:10.1038/s41467-023-44579-z · Cited by 10 · see citing works

MRCKβ links Dasm1 to actin rearrangements to promote dendrite development

Wang, X.-X., Zhang, S., Dong, P.-P., Li, Y., Zhang, L., Shi, S., Yu, Z., & Chen, S. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.100730 · Cited by 9 · see citing works

Integrated analysis of plasma proteome and cortex single-cell transcriptome reveals the novel biomarkers during cortical aging

Niu, R., Feng, W.-Q., Yu, Q.-S., Shi, L., Qin, Q.-M., & Liu, J. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1063861 · Cited by 9 · see citing works

Tyrosine phosphorylation is essential for DSCAML1 to promote dendrite arborization of mouse cortical neurons

Cui, S., Lao, L., Duan, J., Jin, G., & Hou, X. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.09.052 · Cited by 8 · see citing works

Hippocampal overexpression of Down syndrome cell adhesion molecule in amyloid precursor protein transgenic mice

Jia, Y. L., Fu, Z., Zhang, B. H., & Jia, Y. (2017) · Brazilian Journal of Medical and Biological Research · doi:10.1590/1414-431x20176049 · Cited by 8 · see citing works

Genes Associated with Disturbed Cerebral Neurogenesis in the Embryonic Brain of Mouse Models of Down Syndrome

Ishihara, K. (2021) · Genes · doi:10.3390/genes12101598 · Cited by 8 · see citing works

The role of Down syndrome cell adhesion molecule in Down syndrome

Hergenreder, T., Yang, T., & Ye, B. (2024) · Medical Review · doi:10.1515/mr-2023-0056 · Cited by 7 · see citing works

Reversal of neurodevelopmental impairment and cognitive enhancement by pharmacological intervention with the polyphenol polydatin in a Down syndrome model

Emili, M., Stagni, F., Russo, C. A., Angelozzi, L., Guidi, S., & Bartesaghi, R. (2024) · Neuropharmacology · doi:10.1016/j.neuropharm.2024.110170 · Cited by 7 · see citing works

Zebrafish expression reporters and mutants reveal that the IgSF cell adhesion molecule Dscamb is required for feeding and survival

Julien, D. P., Chan, A. W., Barrios, J. P., Mathiaparanam, J., Douglass, A. D., Wolman, M. A., & Sagasti, A. (2018) · Journal of Neurogenetics · doi:10.1080/01677063.2018.1493479 · Cited by 7 · see citing works

Human-specific SRGAP2 paralogs synchronize neotenic microglial maturation and synaptic development

Diaz-Salazar, C., Kim, J., Krzisch, M., Yoo, J., Nano, P. R., Bhaduri, A., Jaenisch, R., Paredes, M., & Polleux, F. (2026) · Neuron · doi:10.1016/j.neuron.2026.07.007 · Cited by 4 · see citing works

Exploring perspectives of Dscam for cognitive deficits: a review of multifunction for regulating neural wiring in homeostasis

Xiong, Y., Li, L., & Zhang, X. (2025) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2025.1575348 · Cited by 3 · see citing works

Developmental role of DSCAM in spinal locomotor circuits

Farah, C. (2017) · Journal of Neurophysiology · doi:10.1152/jn.00487.2016 · Cited by 2 · see citing works

Critical periods and neurodevelopmental brain disorders

Meredith, R. M. (2016) · Wiley eBooks · doi:10.1002/9781118931684.ch4 · Cited by 2 · see citing works

Zebrafish Dscaml1 is Essential for Retinal Patterning and Function of Oculomotor SubcircuitsPreprint

Ma, M., Ramirez, A. D., Wang, T., Roberts, R. L., Harmon, K. E., Schoppik, D., Sharma, A., Kuang, C., Goei, S. L., Gagnon, J. A., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/658161 · Cited by 2 · see citing works

Future Directions for Studying the Potential of Mammalian Dscam in Autism Spectrum Disorder and Alzheimer’s Disease: Insights from Dose Sensitivity

Xiong, Y. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05334-1 · Cited by 1 · see citing works

A Neurodevelopmental Perspective for Autism-Associated Gene Function

Poquérusse, J., & Luikart, B. W. (2017) · OBM Neurobiology · doi:10.21926/obm.neurobiol.1702004 · Cited by 1 · see citing works

Chr21 protein-protein interactions: enrichment in products involved in intellectual disabilities, autism and Late Onset Alzheimer DiseasePreprint

Viard, J., Loe-Mie, Y., Daudin, R., Khelfaoui, M., Plançon, C., Boland, A., Tejedor, F. J., Huganir, R. L., Kim, E., Kinoshita, M., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2019.12.11.872606

Faculty Opinions recommendation of In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation.

Biederer, T. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.734900260.793555848

Additional file 1 of Integrin β3 organizes dendritic complexity of cerebral cortical pyramidal neurons along a tangential gradient

Swinehart, B. D., Bland, K. M., Holley, Z. L., Lopuch, A. J., Casey, Z. O., Handwerk, C. J., & Vidal, G. S. (2020) · Figshare · doi:10.6084/m9.figshare.13467349

Arrêt précoce de la migration neuronale corticale : conséquences cellulaires et comportementales

Martineau, F. S. (2017) · theses.fr (ABES) · doi:10.70675/f493149azf097z4827z86ddzcb8cc00e18f8

The impact of perinatal opioid exposure on neuronal and glial cell development: A consideration of prenatal versus postnatal exposure in animal models

Soengkoeng, R., & Clemens, K. J. (2026) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2026.111711

BDNF-DT and BDNF-AS-DT: novel genes in the BDNF locus

Bach, S. V., Punzi, G., Smith, N. E., Mukherjee, S., Shin, J. H., Chen, Q., Pertea, G. M., Collado‐Torres, L., Maynard, K. R., Page, S. C., et al. (2026) · Molecular Psychiatry · doi:10.1038/s41380-026-03695-0

GenX exposure induces neurodevelopmental impairment and synaptic toxicity in hESC-derived cerebral organoids

Hyun, S., Lee, Y.-J., Ko, M. Y., Min, E., Park, H., Kim, Y., Hwang, D. Y., Lee, B.-S., & Ka, M. (2026) · Materials Today Bio · doi:10.1016/j.mtbio.2026.103458

DSCAM and DSCAML1 regulate the radial migration and callosal projection in developing cerebral cortex.

Zhang, L., Huang, Y., Chen, J.-Y., Ding, Y.-Q., & Song, N.-N. (2015) · Brain Research · doi:10.1016/j.brainres.2014.10.060 · Cited by 31 · see citing works

DSCAM differentially modulates pre- and postsynaptic structural and functional central connectivity during visual system wiring

Santos, R. A., Fuertes, A. J. C., Short, G., Donohue, K. C., Shao, H., Quintanilla, J., Malakzadeh, P., & Cohen‐Cory, S. (2018) · Neural Development · doi:10.1186/s13064-018-0118-5 · Cited by 28 · see citing works

Dscam1 Is Required for Normal Dendrite Growth and Branching But Not for Dendritic Spacing inDrosophilaMotoneurons

Hutchinson, K. M., Vonhoff, F., & Duch, C. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.3448-13.2014 · Cited by 31 · see citing works

Migrating Pyramidal Neurons Require DSCAM to Bypass the Border of the Developing Cortical Plate

Yang, T., Veling, M. W., Zhao, X., Prin, N. P., Zhu, L., Hergenreder, T., Liu, H., Liu, L., Rane, Z. S., Savelieff, M. G., et al. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.0997-21.2022 · Cited by 9 · see citing works

Restoring DSCAM expression rescues neuronal morphology and axon guidance deficits in Down syndromePreprint

Agrawal, M., Kirkise, N., Rygel, K., Sahoo, P. K., Vincent, C. J., Joyner, D., Aguilar-Alvarez, R., Philip, T. R., Dhillon, P. S., Patel, J., et al. (2025) · bioRxiv · doi:10.1101/2025.07.25.666804 · Cited by 1 · see citing works