Dysregulated miRNA biogenesis downstream of cellular stress and ALS‐causing mutations: a new mechanism for ALS
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Some snoRNAs such as Snord70 and Snord66, often used as normalization controls in qPCR-based assays, are expressed in a tissue-biased manner.
“we show that some snoRNAs, such as Snord70 and Snord66, which are often used as normalization controls in qPCR-based assays (36, 37), are also expressed in a tissue-biased manner”
From A mouse tissue atlas of small noncoding RNA (2020) · cites this paper as [37]
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Cites
Rosen, D. R., Siddique, T., Patterson, D., Figlewicz, D. A., Sapp, P., Hentati, A., Donaldson, D., Goto, J., O'Regan, J. P., Deng, H.-X., et al. (1993) · Nature · doi:10.1038/362059a0 · Cited by 7,062 · see citing works
Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
Ling, S.-C., Polymenidou, M., & Cleveland, D. W. (2013) · Neuron · doi:10.1016/j.neuron.2013.07.033 · Cited by 1,811 · see citing works
Peterson, A. C., Russell, J. D., Bailey, D. J., Westphall, M. S., & Coon, J. J. (2012) · Molecular & Cellular Proteomics · doi:10.1074/mcp.o112.020131 · Cited by 1,288 · see citing works
A cytosolic iron chaperone that delivers iron to ferritin
Shi, H., Bencze, K. Z., Stemmler, T. L., & Philpott, C. C. (2008) · Science · doi:10.1126/science.1157643 · Cited by 536 · see citing works
Design, power, and interpretation of studies in the standard murine model of ALS
Scott, S., Kranz, J. E., Cole, J., Lincecum, J. M., Thompson, K., Kelly, N., Bostrom, A., Theodoss, J., Al‐Nakhala, B. M., Vieira, F. G., et al. (2008) · Amyotrophic Lateral Sclerosis · doi:10.1080/17482960701856300 · Cited by 504 · see citing works
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Research works printed but not linked: 4
- Droppelmann CA, Wang J, Campos-Melo D, Keller B, Volkening K, Hegele RA, Strong MJ (2013) Detection of a novel frameshift mutation and regions with homozygosis within ARHGEF28 gene in familial amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener 14: 444 -451 The EMBO Journal Vol 34 | No 21 | 2015 ª 2015 The Authors
- Lee Y, Hur I, Park SY, Kim YK, Suh MR, Kim VN (2006) The role of PACT in the RNA silencing pathway. EMBO J 25: 522 -532 ª 2015 The Authors The EMBO Journal Vol 34 | No 21 | 2015
- Shan G, Li Y, Zhang J, Li W, Szulwach KE, Duan R, Faghihi MA, Khalil AM, Lu L, Paroo Z, Chan AW, Shi Z, Liu Q, Wahlestedt C, He C, Jin P (2008) A The EMBO Journal Vol 34 | No 21 | 2015 ª 2015 The Authors small molecule enhances RNA interference and promotes microRNA processing. Nat Biotechnol 26: 933 -940
- Zhang Z, Almeida S, Lu Y, Nishimura AL, Peng L, Sun D, Wu B, Karydas AM, Tartaglia MC, Fong JC, Miller BL, Farese RV Jr, Moore MJ, Shaw CE, Gao FB (2013) Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations. PLoS ONE 8: e76055 ª 2015 The Authors The EMBO Journal Vol 34 | No 21 | 2015
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Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS
Krug, L., Chatterjee, N., Borges-Monroy, R., Hearn, S., Liao, W.-W., Morrill, K., Prazak, L., Rozhkov, N., Theodorou, D., Hammell, M., et al. (2017) · PLOS Genetics · doi:10.1371/journal.pgen.1006635 · Cited by 201 · see citing works
Varcianna, A., Myszczynska, M. A., Castelli, L. M., O'Neill, B., Kim, Y., Talbot, J., Nyberg, S., Nyamali, I., Heath, P. R., Stopford, M. J., et al. (2019) · EBioMedicine · doi:10.1016/j.ebiom.2018.11.067 · Cited by 194 · see citing works
A mouse tissue atlas of small noncoding RNA
Isakova, A., Fehlmann, T., Keller, A., & Quake, S. R. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2002277117 · Cited by 119 · see citing works
De Santis, R., Santini, L., Colantoni, A., Peruzzi, G., de Turris, V., Alfano, V., Bozzoni, I., & Rosa, A. (2017) · Stem Cell Reports · doi:10.1016/j.stemcr.2017.09.004 · Cited by 91 · see citing works
Pang, T. Y., Short, A. K., Bredy, T. W., & Hannan, A. J. (2017) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2017.02.007 · Cited by 61 · see citing works
Eitan, C., Siany, A., Barkan, E., Olender, T., van Eijk, K. R., Moisse, M., Farhan, S. M. K., Danino, Y. M., Yanowski, E., Marmor-Kollet, H., et al. (2022) · Nature Neuroscience · doi:10.1038/s41593-022-01040-6 · Cited by 38 · see citing works
Self-citationModulation of the miR-485-3p/PGC-1α Pathway by ASO-Loaded Nanoparticles Attenuates ALS Pathogenesis
Ryu, I. S., Ha, D.-I., Jung, Y.-J., Lee, H. J., Kim, I., Lim, Y. N., Min, H. S., Kim, S. H., Yoon, I., Cho, H.-J., et al. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27020615 · Cited by 2 · see citing works
- Authors
- Emde, A., Eitan, C., Liou, L., Libby, R. T., Rivkin, N., Magen, I., Reichenstein, I., Oppenheim, H., Eilam, R., Silvestroni, A., Alajajian, B., Ben‐Dov, I. Z., Aebischer, J., Savidor, A., Levin, Y., Sons, R., Hammond, S. M., Ravits, J. M., Möller, T., & Hornstein, E.
- Venue
- The EMBO Journal
- Published
- 2015-09-01
- Volume
- 34
- Issue
- 21
- Pages
- 2633-2651
- ISSN
- 0261-4189
- 1460-2075
- Cited by
- 215
- References
- 5
- Language
- en
- Funders
- Israel Science Foundation
- ISF Legacy‐heritage Program
- Bruno and Ilse Frick Foundation
- Yeda‐Sela
- Yeda‐CEO
- Minna‐James‐Heineman Stiftung through Minerva
- ERC Consolidator Program
- Israel Ministry of Trade and Industry “Kamin Program
- Nella and Leon Benoziyo Center for Neurological Diseases
- Y. Leon Benoziyo Institute for Molecular Medicine
- ALS‐Therapy Alliance
- Kekst Family Institute for Medical Genetics
- David and Fela Shapell Family Center for Genetic Disorders Research
- Crown Human Genome Center
- Nathan, Shirley, Philip and Charlene Vener New Scientist Fund
- Julius and Ray Charlestein Foundation
- Fraida Foundation
- Wolfson Family Charitable Trust
- Adelis Foundation
- MERCK UK
- Maria Halphen
- Estates of Fannie Sherr
- Lola Asseof
- Lilly Fulop
- Teva NNE Program and miCure Therapeutics
- ALS Association (1765)
- NIH (T32, NS051171)
- Microsoft Research
- Deutsche Forschungsgemeinschaft
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