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Membrane scission driven by the PROPPIN Atg18
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BECN1 and PIK3C3/VPS34 are essential partners in the autophagy interactome that signals the onset of autophagy.
“BECN1 (yeast Vps30/Atg6) and PIK3C3/VPS34 are essential partners in the autophagy interactome that signals the onset of autophagy [790, 840, 841],”
From Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 (2021) · cites this paper as [840]
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Global analysis of protein expression in yeast
Ghaemmaghami, S., Huh, W.-K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., & Weissman, J. S. (2003) · Nature · doi:10.1038/nature02046 · Cited by 3,750
Kulak, N. A., Pichler, G., Paron, I., Nagaraj, N., & Mann, M. (2014) · Nature Methods · doi:10.1038/nmeth.2834 · Cited by 1,719
An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis
Mari, M., Griffith, J., Rieter, E., Krishnappa, L., Klionsky, D. J., & Reggiori, F. (2010) · Journal of Cell Biology · doi:10.1083/jcb.200912089 · Cited by 491
Endocytosis and Autophagy: Exploitation or Cooperation?
Tooze, S. A., Abada, A., & Elazar, Z. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a018358 · Cited by 202
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Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons
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“Both WIPI1 and WIPI2 are predicted to form an amphipathic a-helix upon lipid binding, similar to the yeast homolog, Atg18 (Gopaldass et al., 2017), which can promote membrane deformation.”
BackgroundInfluential
Metadata
- Authors
- Gopaldass, N., Fauvet, B., Lashuel, H., Roux, A., & Mayer, A.
- Venue
- The EMBO Journal
- Published
- 2017-10-13
- Volume
- 36
- Issue
- 22
- Pages
- 3274-3291
- ISSN
- 0261-4189
- 1460-2075
- Cited by
- 104
- References
- 4
- Language
- en
- Funders
- H2020 European Research Council (233458)
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (144258)
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