Use of d-Lysergic Acid Diethylamide in the Treatment of Alcoholism

Chwelos, N.; Blewett, D. B.; Smith, C. M.; Hoffer, A.

doi:10.15288/qjsa.1959.20.577

Cited by 112Substance Abuse Treatment and OutcomesNeurotransmitter Receptor Influence on BehaviorPsychedelics and Drug Studies

Use of d-Lysergic Acid Diethylamide in the Treatment of Alcoholism

Chwelos, N., Blewett, D. B., Smith, C. M., Hoffer, A.·1959·Quarterly Journal of Studies on Alcohol

DOI 10.15288/qjsa.1959.20.577

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Patients with alcohol use disorder may tend to display more tolerance to serotonergic psychedelics.
“early studies with LSD and contemporary studies with psilocybin suggest that patients with AUD may tend to display more tolerance to serotonergic psychedelics”
From Psilocybin-assisted therapy for severe alcohol use disorder: protocol for a double-blind, randomized, placebo-controlled, 7-month parallel-group phase II superiority trial (2024) · cites this paper as [78]
High doses of 30-40 mg/70 kg of psilocybin are well tolerated in patients with alcohol use disorder.
“whereas high doses of 30–40 mg/70 kg are well tolerated in this population [15, 54, 78].”
From Psilocybin-assisted therapy for severe alcohol use disorder: protocol for a double-blind, randomized, placebo-controlled, 7-month parallel-group phase II superiority trial (2024) · cites this paper as [78]

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Authors: Chwelos, N., Blewett, D. B., Smith, C. M., & Hoffer, A.
Affiliations: Saskatchewan Health (CA)
Deputy Director, Psychiatric Research, Department of Public Health, University Hospital, Saskatoon, Sask.
Royal University Hospital (CA)
ORCID: Hoffer, A.
Venue: Quarterly Journal of Studies on Alcohol
Publisher: Alcohol Research Documentation, Inc.
Published: 1959-09-01
Volume: 20
Issue: 3
Pages: 577-590
ISSN: 0033-5649 (ISSN-L)
1946-7214
DOI: 10.15288/qjsa.1959.20.577
OpenAlex: W2297304494
Cited by: 111
References: 0
Citations by year: 2026: 5 · 2025: 9 · 2024: 8 · 2023: 3 · 2022: 4 · 2021: 3 · 2020: 4 · 2019: 3 · 2018: 5 · 2017: 6 · 2016: 7 · 2015: 3 · 2014: 1 · 2013: 3
FWCI: 0.00
Type: journal article
Language: en
Open access: closed
Locations: Quarterly Journal of Studies on Alcohol (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Social Sciences › Psychology › Clinical Psychology › Psychedelics and Drug Studies
Keywords: lysergic acid diethylamide, LSD, alcoholism treatment, psychedelic therapy, alcoholism
MeSH terms: Alcoholism, Lysergic Acid Diethylamide

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