The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Current vitamin D status in European and Middle East countries and strategies to prevent vitamin D deficiency: a position statement of the European Calcified Tissue Society
Open accessAbstract
Vitamin D deficiency (serum 25-hydroxyvitamin D (25(OH)D) <50 nmol/L or 20 ng/mL) is common in Europe and the Middle East. It occurs in <20% of the population in Northern Europe, in 30–60% in Western, Southern and Eastern Europe and up to 80% in Middle East countries. Severe deficiency (serum 25(OH)D <30 nmol/L or 12 ng/mL) is found in >10% of Europeans. The European Calcified Tissue Society (ECTS) advises that the measurement of serum 25(OH)D be standardized, for example, by the Vitamin D Standardization Program. Risk groups include young children, adolescents, pregnant women, older people (especially the institutionalized) and non-Western immigrants. Consequences of vitamin D deficiency include mineralization defects and lower bone mineral density causing fractures. Extra-skeletal consequences may be muscle weakness, falls and acute respiratory infection, and are the subject of large ongoing clinical trials. The ECTS advises to improve vitamin D status by food fortification and the use of vitamin D supplements in risk groups. Fortification of foods by adding vitamin D to dairy products, bread and cereals can improve the vitamin D status of the whole population, but quality assurance monitoring is needed to prevent intoxication. Specific risk groups such as infants and children up to 3 years, pregnant women, older persons and non-Western immigrants should routinely receive vitamin D supplements. Future research should include genetic studies to better define individual vulnerability for vitamin D deficiency, and Mendelian randomization studies to address the effect of vitamin D deficiency on long-term non-skeletal outcomes such as cancer.
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Cites
Holick, M. F. (2007) · New England Journal of Medicine · doi:10.1056/nejmra070553 · Cited by 13,720
Martineau, A. R., Jolliffe, D. A., Hooper, R. L., Greenberg, L., Aloia, J. F., Bergman, P., Dubnov-Raz, G., Esposito, S., Ganmaa, D., Ginde, A. A., et al. (2017) · BMJ · doi:10.1136/bmj.i6583 · Cited by 2,040
Global vitamin D status and determinants of hypovitaminosis D
on behalf of the IOF Committee of Scientific Advisors (CSA) Nutrition Working Group, Mithal, A., Wahl, D. A., Bonjour, J.-P., Burckhardt, P., Dawson-Hughes, B., Eisman, J. A., El-Hajj Fuleihan, G., Josse, R. G., Lips, P., et al. (2009) · Osteoporosis International · doi:10.1007/s00198-009-0954-6 · Cited by 1,472
Self-citationVitamin D Receptor Expression in Human Muscle Tissue Decreases with Age
Bischoff-Ferrari, H., Borchers, M., Gudat, F., Dürmüller, U., Stähelin, H., & Dick, W. (2004) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2004.19.2.265 · Cited by 585
Self-citationVitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Avenell, A., Mak, J. C., & O'Connell, D. L. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000227.pub4 · Cited by 482
Effect of Vitamin D Supplementation on Testosterone Levels in Men
Pilz, S., Frisch, S., Koertke, H., Kuhn, J., Dreier, J., Obermayer-Pietsch, B., Wehr, E., & Zittermann, A. (2011) · Hormone and Metabolic Research · doi:10.1055/s-0030-1269854 · Cited by 325
Self-citationAssociation of vitamin D status with serum androgen levels in men
Wehr, E., Pilz, S., Boehm, B. O., März, W., & Obermayer‐Pietsch, B. (2010) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2009.03777.x · Cited by 253
Self-citationHenderson, C. M., Lutsey, P. L., Misialek, J. R., Laha, T. J., Selvin, E., Eckfeldt, J. H., & Hoofnagle, A. N. (2016) · Clinical Chemistry · doi:10.1373/clinchem.2015.244541 · Cited by 140
Vitamin D supplementation and testosterone concentrations in male human subjects
Heijboer, A. C., Oosterwerff, M., Schroten, N. F., Eekhoff, E. M. W., Chel, V. G. M., de Boer, R. A., Blankenstein, M. A., & Lips, P. (2015) · Clinical Endocrinology · doi:10.1111/cen.12711 · Cited by 63
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The health effects of vitamin D supplementation: Evidence from human studies
Bouillon, R., Manousaki, D., Rosen, C., Trajanoska, K., Rivadeneira, F., & Richards, J. B. (2022) · Nature Reviews Endocrinology · doi:10.1038/s41574-021-00593-z · Cited by 535
Self-citationConsensus statement on vitamin D status assessment and supplementation: Whys, whens, and hows
Giustina, A., Bilezikian, J. P., Adler, R. A., Banfi, G., Bikle, D. D., Binkley, N. C., Bollerslev, J., Bouillon, R., Brandi, M. L., Casanueva, F. F., et al. (2024) · Endocrine Reviews · doi:10.1210/endrev/bnae009 · Cited by 392
Self-citationBischoff-Ferrari, H. A., Vellas, B., Rizzoli, R., Kressig, R. W., da Silva, J. A. P., Blauth, M., Felson, D. T., McCloskey, E. V., Watzl, B., Hofbauer, L. C., et al. (2020) · JAMA · doi:10.1001/jama.2020.16909 · Cited by 353
Self-citationSunscreen photoprotection and vitamin D status
Passeron, T., Bouillon, R., Callender, V., Cestari, T., Diepgen, T. L., Green, A. C., van der Pols, J. C., Bernard, B. A., Ly, F., Bernerd, F., et al. (2019) · British Journal of Dermatology · doi:10.1111/bjd.17992 · Cited by 200
Self-citationOsteoporosis in patients with chronic kidney diseases: A systemic review
Hsu, C.-Y., Chen, L.-R., & Chen, K.-H. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21186846 · Cited by 162
Metadata
- Authors
- Lips, P., Cashman, K. D., Lamberg-Allardt, C., Bischoff-Ferrari, H. A., Obermayer-Pietsch, B., Bianchi, M. L., Stepan, J., El-Hajj Fuleihan, G., & Bouillon, R.
- Venue
- European Journal of Endocrinology
- Publisher
- Oxford University Press (OUP)
- Published
- 2019-04
- Volume
- 180
- Issue
- 4
- Pages
- P23-P54
- ISSN
- 0804-4643 (ISSN-L)
- 1479-683X
- OpenAlex
- W2913249953
- Cited by
- 662
- References
- 9
- FWCI
- 56.02
- Type
- journal article
- Language
- en
- Open access
- green
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