The DOI matches its Crossref record; 106 of the 106 references it cites were found in a registry or an index.
Molecular genetics of adrenocortical tumours, from familial to sporadic diseases
Abstract
Adrenal masses can be detected in up to 4% of the population, and are mostly of adrenocortical origin. Adrenocortical tumours (ACTs) may be responsible for excess steroid production and, in the case of adrenocortical cancers, for morbidity or mortality due to tumour growth. Our understanding of the pathogenesis of ACTs is more limited than that for other tumours. However, studies of the genetics of ACTs have led to major advances in this field in the last decade. The identification of germline molecular defects in the hereditary syndrome responsible for ACTs has facilitated progress. Indeed, similar molecular defects have since been identified as somatic alterations in sporadic tumours. The familial diseases concerned are Li-Fraumeni syndrome, which may be due to germline mutation of the tumour-suppressor gene TP53 and Beckwith-Wiedemann syndrome, which is caused by dys-regulation of the imprinted IGF-II locus at 11p15. ACTs also occur in type 1 multiple endocrine neoplasia (MEN 1), which is characterized by a germline mutation of the menin gene. Cushing's syndrome due to primary pigmented nodular adrenocortical disease (PPNAD) has been observed in Carney complex patients presenting inactivating germline PRKAR1A mutations. Interestingly, allelic losses at 17p13 and 11p15 have been demonstrated in sporadic adrenocortical cancer and somatic PRKAR1A mutations have been found in secreting adrenocortical adenomas. More rarely, mutations in Gs protein (gsp) and the gene for ACTH receptor have been observed in ACTs. The genetics of another group of adrenal diseases that can lead to adrenal nodular hyperplasia -- congenital adrenal hyperplasia (CAH) and glucocorticoid-remediable aldosteronism (GRA) -- have also been studied extensively. This review summarizes recent advances in the genetics of ACTs, highlighting both improvements in our understanding of the pathophysiology and the diagnosis of these tumours.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Perturbation of the IGF2 locus, with upregulation of maternally imprinted genes (IGF2), and downregulation of paternally imprinted genes (H19 and CDKN1C), is frequently observed in ACCs (226).”
From Adrenocortical carcinoma (2014) · cites this paper as [226]
Citations
Cites
Parental imprinting of the mouse insulin-like growth factor II gene
DeChiara, T. M., Robertson, E. J., & Efstratiadis, A. (1991) · Cell · doi:10.1016/0092-8674(91)90513-x · Cited by 1,804
Activating Mutations of the Stimulatory G Protein in the McCune–Albright Syndrome
Weinstein, L. S., Shenker, A., Gejman, P. V., Merino, M. J., Friedman, E., & Spiegel, A. M. (1991) · New England Journal of Medicine · doi:10.1056/nejm199112123252403 · Cited by 1,697
Kirschner, L. S., Carney, J. A., Pack, S. D., Taymans, S. E., Giatzakis, C., Cho, Y. S., Cho-Chung, Y. S., & Stratakis, C. A. (2000) · Nature Genetics · doi:10.1038/79238 · Cited by 1,153
The Complex of Myxomas, Spotty Pigmentation, and Endocrine Overactivity
Carney, J. A., Gordon, H., Carpenter, P. C., Shenoy, B. V., & Go, V. L. W. (1985) · Medicine · doi:10.1097/00005792-198507000-00007 · Cited by 1,110
Matsuoka, S., Edwards, M. C., Bai, C., Parker, S., Zhang, P., Baldini, A., Harper, J. W., & Elledge, S. J. (1995) · Genes & Development · doi:10.1101/gad.9.6.650 · Cited by 952
Heterozygous Germ Line hCHK2 Mutations in Li-Fraumeni Syndrome
Bell, D. W., Varley, J. M., Szydlo, T. E., Kang, D. H., Wahrer, D. C. R., Shannon, K. E., Lubratovich, M. L., Verselis, S. J., Isselbacher, K. J., Fraumeni, J. F., et al. (1999) · Science · doi:10.1126/science.286.5449.2528 · Cited by 899
Lee, M., Reynisdóttir, I., & Massagué, J. (1995) · Genes & Development · doi:10.1101/gad.9.6.639 · Cited by 889
Relaxation of imprinted genes in human cancer
Rainier, S. R., Johnson, L. A., Dobry, C. J., Ping, A. J., Grundy, P. E., & Feinberg, A. P. (1993) · Nature · doi:10.1038/362747a0 · Cited by 795
Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour
Ogawa, O., Eccles, M. R., Szeto, J., McNoe, L. A., Yun, K., Maw, M. A., Smith, P. J., & Reeve, A. E. (1993) · Nature · doi:10.1038/362749a0 · Cited by 706
Tumour-suppressor activity of H19 RNA
Hao, Y., Crenshaw, T., Moulton, T. A., Newcomb, E. W., & Tycko, B. (1993) · Nature · doi:10.1038/365764a0 · Cited by 629
Flagged first, then by citations
Research works printed but not linked: 21
- Beuschlein, 1994, Cancer Research, 54, 4927
- Mesiano, 1993, Journal of Clinical Endocrinology & Metabolism, 76, 968, 10.1210/jc.76.4.968 · DOI · Paper page
- Gicquel, 1992, Journal of Clinical Endocrinology & Metabolism, 75, 472, 10.1210/jc.75.2.472 · DOI
- Groussin, 2002, Journal of Clinical Endocrinology & Metabolism, 87, 1980, 10.1210/jc.87.5.1980 · DOI
- 1998, BULLETIN DE LRSQUOACADEMIE NATIONALE DE MEDECINE, 182, 1839
- N'Diaye, 1998, Journal of Clinical Endocrinology & Metabolism, 83, 2781, 10.1210/jc.83.8.2781 · DOI
- Kjellman, 1996, Cancer Research, 56, 4219
- Sidhu, 2002, Journal of Clinical Endocrinology & Metabolism, 87, 3467, 10.1210/jc.87.7.3467 · DOI
- Gicquel, 2001, Cancer Research, 61, 6762
- Latronico, 2001, Journal of Clinical Endocrinology & Metabolism, 86, 4970, 10.1210/jc.86.10.4970 · DOI · Paper page
- Reincke, 1994, Journal of Clinical Endocrinology & Metabolism, 78, 790, 10.1210/jc.78.3.790 · DOI
- Reincke, 1996, Journal of Clinical Endocrinology & Metabolism, 81, 3636, 10.1210/jc.81.10.3636 · DOI
- Bertherat, 2003, Cancer Research, 63, 5308
- Ilvesmaki, 1993, Journal of Clinical Endocrinology & Metabolism, 77, 852, 10.1210/jc.77.3.852 · DOI
- Boulle, 2000, Endocrinology, 141, 3127, 10.1210/en.141.9.3127 · DOI
- Gao, 2002, Journal of Clinical Endocrinology & Metabolism, 87, 1170, 10.1210/jc.87.3.1170 · DOI
- Jaresch, 1992, Journal of Clinical Endocrinology & Metabolism, 74, 685, 10.1210/jc.74.3.685 · DOI · Paper page
- Beuschlein, 1998, Journal of Clinical Endocrinology & Metabolism, 83, 2585, 10.1210/jc.83.7.2585 · DOI
- Latronico, 1995, Journal of Clinical Endocrinology & Metabolism, 80, 875, 10.1210/jc.80.3.875 · DOI
- Groussin, 2000, Journal of Clinical Endocrinology & Metabolism, 85, 345, 10.1210/jc.85.1.345 · DOI
- Peri, 2001, Journal of Clinical Endocrinology & Metabolism, 86, 5443, 10.1210/jc.86.11.5443 · DOI
Cited by
Sorted by citations
Else, T., Kim, A. C., Sabolch, A., Raymond, V. M., Kandathil, A., Caoili, E. M., Jolly, S., Miller, B. S., Giordano, T. J., & Hammer, G. D. (2014) · Endocrine Reviews · doi:10.1210/er.2013-1029 · Cited by 892
Adrenocortical Carcinoma: Clinical Update
Allolio, B., & Fassnacht, M. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-2639 · Cited by 775
Beyond Li Fraumeni Syndrome: Clinical Characteristics of Families With p53 Germline Mutations
Hagman, K. D. F., Noltner, K., Buzin, C. H., Gu, D., Wen, C. Y., Nguyen, V. Q., Han, J., Lowstuter, K. J., Longmate, J., Sommer, S. S., et al. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.16.6959 · Cited by 607
Hampel, H., Bennett, R. L., Buchanan, A. H., Pearlman, R., & Wiesner, G. L. (2014) · Genetics in Medicine · doi:10.1038/gim.2014.147 · Cited by 606
Abiven, G., Coste, J., Groussin, L., Anract, P., Tissier, F., Legmann, P., Dousset, B., Bertagna, X., & Bertherat, J. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-2730 · Cited by 435
Self-citationMolecular classification and prognostication of adrenocortical tumors by transcriptome profiling
Giordano, T. J., Kuick, R., Else, T., Gauger, P. G., Vinco, M., Bauersfeld, J., Sanders, D., Thomas, D. G., Doherty, G., & Hammer, G. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-08-1067 · Cited by 401
Clinical management of adrenocortical carcinoma
Fassnacht, M., & Allolio, B. (2009) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2008.10.008 · Cited by 349
Menin: a scaffold protein that controls gene expression and cell signaling
Matkar, S. S., Thiel, A. T., & Hua, X. (2013) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2013.05.005 · Cited by 295
Adrenocortical cancer: pathophysiology and clinical management
Libé, R., Fratticci, A., & Bertherat, J. Y. (2007) · Endocrine Related Cancer · doi:10.1677/erc.1.01130 · Cited by 271
Self-citationBlake, M. A., Cronin, C. G., & Boland, G. W. (2010) · American Journal of Roentgenology · doi:10.2214/ajr.10.4547 · Cited by 254
The Weiss system for evaluating adrenocortical neoplasms: 25 years later
Lau, S. K., & Weiss, L. M. (2009) · Human Pathology · doi:10.1016/j.humpath.2009.03.010 · Cited by 223
Gaujoux, S., Tissier, F., Groussin, L., Libé, R., Ragazzon, B., Launay, P., Audebourg, A., Dousset, B., Bertagna, X., & Bertherat, J. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-0631 · Cited by 142
Self-citationChildhood adrenocortical tumours
Ribeiro, R. C., & de Figueiredo, B. C. (2004) · European Journal of Cancer · doi:10.1016/j.ejca.2004.01.031 · Cited by 140
Stratakis, C. A., & Boikos, S. A. (2007) · Nature Clinical Practice Endocrinology & Metabolism · doi:10.1038/ncpendmet0648 · Cited by 129
Wnt/β-catenin signalling in adrenal physiology and tumour development
Berthon, A., Martinez, A., Bertherat, J., & Val, P. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.09.009 · Cited by 125
Self-citationPhosphodiesterase 11A (PDE11A) and Genetic Predisposition to Adrenocortical Tumors
Libé, R., Fratticci, A., Coste, J., Tissier, F., Horvath, A., Ragazzon, B., René-Corail, F., Groussin, L., BERTAGNA, X. Y., Raffin‐Sanson, M. L., et al. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-08-0106 · Cited by 128
Self-citationLi‐Fraumeni syndrome: a paradigm for the understanding of hereditary cancer predisposition
Valdez, J. M., Nichols, K. E., & Kesserwan, C. A. (2016) · British Journal of Haematology · doi:10.1111/bjh.14461 · Cited by 124
Libè, R., Groussin, L., Tissier, F., Elie, C., René-Corail, F., Fratticci, A., Jullian, E., Beck-Peccoz, P., Bertagna, X., Gicquel, C., et al. (2007) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-06-2085 · Cited by 115
Self-citationLarge Deletions of the PRKAR1A Gene in Carney Complex
Horvath, A., Bossis, I., Giatzakis, C., Levine, E., Weinberg, F. D., Meoli, E., Robinson-White, A. J., Siegel, J., Soni, P., Groussin, L., et al. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-07-1155 · Cited by 106
Self-citationMenin Epigenetically Represses Hedgehog Signaling in MEN1 Tumor Syndrome
Gurung, B., Feng, Z., Iwamoto, D. V., Thiel, A. T., Jin, G., Fan, C.-M., Ng, J. M. Y., Curran, T., & Hua, X. (2013) · Cancer Research · doi:10.1158/0008-5472.can-12-3158 · Cited by 101
Current management of adrenal tumors
Kuruba, R., & Gallagher, S. F. (2008) · Current Opinion in Oncology · doi:10.1097/cco.0b013e3282f301fd · Cited by 85
Genetics of tumors of the adrenal cortex
Bonnet-Serrano, F., & Bertherat, J. (2018) · Endocrine Related Cancer · doi:10.1530/erc-17-0361 · Cited by 80
Self-citationRole of the Insulin-like Growth Factor System in Adrenocortical Growth Control and Carcinogenesis
Fottner, C., Hoeflich, A., Wolf, E., & Weber, M. (2004) · Hormone and Metabolic Research · doi:10.1055/s-2004-814563 · Cited by 78
Transcriptional profiling enables molecular classification of adrenocortical tumours
Laurell, C., Velázquez‐Fernández, D., Lindsten, K., Juhlin, C. C., Enberg, U., Geli, J., Höög, A., Kjellman, M., Lundeberg, J., Hamberger, B., et al. (2009) · European Journal of Endocrinology · doi:10.1530/eje-09-0068 · Cited by 77
Adrenocortical carcinoma: The management of metastatic disease
Fay, A. P., Elfiky, A. A., Teló, G. H., McKay, R. R., Kaymakcalan, M. D., Nguyen, P. L., Vaidya, A., Ruan, D. T., Joaquim Bellmunt, B., & Choueiri, T. K. (2014) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2014.05.009 · Cited by 69
Update on tumours of the adrenal cortex, phaeochromocytoma and extra‐adrenal paraganglioma
McNicol, A. M. (2010) · Histopathology · doi:10.1111/j.1365-2559.2010.03613.x · Cited by 68
REVIEW PAPER: Origin and Molecular Pathology of Adrenocortical Neoplasms
Bielińska, M., Parviainen, H., Kiiveri, S., Heikinheimo, M., & Wilson, D. B. (2009) · Veterinary Pathology · doi:10.1354/vp.08-vp-0179-w-rev · Cited by 68
de Crémoux, P., Rosenberg, D., Goussard, J., Brémont-Weil, C., Tissier, F., Tran‐Perennou, C., Groussin, L., BERTAGNA, X. Y., Bertherat, J. Y., & Raffin‐Sanson, M. (2008) · Endocrine Related Cancer · doi:10.1677/erc-07-0081 · Cited by 63
Self-citationThe molecular genetics of adrenocortical carcinoma
Barlaskar, F. M., & Hammer, G. D. (2007) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-007-9057-x · Cited by 56
Delhanty, P. J. D., van Koetsveld, P. M., Gauna, C., van de Zande, B., Vitale, G., Hofland, L. J., & van der Lely, A. J. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00377.2006 · Cited by 55
Adam, P., Hahner, S., Hartmann, M., Heinrich, B., Quinkler, M. O., Willenberg, H. S., Saeger, W., Sbiera, S., Schmull, S., Voelker, H.-U., et al. (2010) · Modern Pathology · doi:10.1038/modpathol.2010.153 · Cited by 55
Pathogenesis of adrenocortical cancer
Bertherat, J. Y., & BERTAGNA, X. Y. (2009) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2008.10.006 · Cited by 55
Self-citationSutter, J. A., & Grimberg, A. (2006) · PubMed · Cited by 51
GENETICS IN ENDOCRINOLOGY: Glucocorticoid resistance syndrome
Vitellius, G., & Lombès, M. (2019) · European Journal of Endocrinology · doi:10.1530/eje-19-0811 · Cited by 49
Gust, L., Taïeb, D., Beliard, A., Barlier, A., Morange, I., Micco, C. D., Henry, J., & Sebag, F. A. (2011) · World Journal of Surgery · doi:10.1007/s00268-011-1374-2 · Cited by 48
Martino, M. C. D., van Koetsveld, P. M., Feelders, R. A., Sprij-Mooij, D. M., Waaijers, M., Lamberts, S. W. J., de Herder, W. W., Colao, A., Pivonello, R., & Hofland, L. J. (2012) · Endocrine Related Cancer · doi:10.1530/erc-11-0270 · Cited by 48
Menin Directly Represses Gli1 Expression Independent of Canonical Hedgehog Signaling
Gurung, B., Feng, Z., & Hua, X. (2013) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-13-0170 · Cited by 46
Clinical impact of TP53 alterations in adrenocortical carcinomas
Waldmann, J., Patsalis, N., Fendrich, V., Langer, P., Saeger, W., Chaloupka, B., Ramaswamy, A., Faßnacht, M., Bartsch, D. K., & Slater, E. P. (2011) · Langenbeck s Archives of Surgery · doi:10.1007/s00423-011-0868-6 · Cited by 45
Assié, G., Guillaud-Bataille, M., Ragazzon, B., BERTAGNA, X. Y., Bertherat, J. Y., & Clauser, É. (2010) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2009.12.009 · Cited by 48
Self-citationP53/Rb inhibition induces metastatic adrenocortical carcinomas in a preclinical transgenic model
Batisse‐Lignier, M., Sahut‐Barnola, I., Tissier, F., Dumontet, T., Mathieu, M., Drelon, C., Pointud, J.-C., Damon‐Soubeyrand, C., Marceau, G., Kemeny, J.-L., et al. (2017) · Oncogene · doi:10.1038/onc.2017.54 · Cited by 42
Self-citationThe Genetics of Adrenocortical Tumors
Espiard, S., & Bertherat, J. Y. (2015) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2015.02.004 · Cited by 47
Self-citationGene expression profiling in adrenocortical neoplasia
Assié, G., Giordano, T. J., & Bertherat, J. Y. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.09.044 · Cited by 41
Self-citationLi–Fraumeni syndrome heterogeneity
Gargallo, P., Yáñez, Y., Segura, V., Juan, A., Torres, B., Balaguer, J., Oltra, S., Castel, V., & Cañete, A. (2019) · Clinical & Translational Oncology · doi:10.1007/s12094-019-02236-2 · Cited by 41
Mechanisms of Disease: adrenocortical tumors—molecular advances and clinical perspectives
Bertherat, J. Y., Groussin, L., & BERTAGNA, X. Y. (2006) · Nature Clinical Practice Endocrinology & Metabolism · doi:10.1038/ncpendmet0321 · Cited by 40
Self-citationThe indeterminate adrenal lesion
Sahdev, A., Willatt, J. M., Francis, I. R., & Reznek, R. H. (2010) · Cancer Imaging · doi:10.1102/1470-7330.2010.0012 · Cited by 39
Martino, M. C. D., van Koetsveld, P. M., Feelders, R. A., de Herder, W. W., Dogan, F., Janssen, J. A. M. J. L., Bruinink, D. H. O., Pivonello, C., Waaijers, A. M., Colao, A., et al. (2019) · Endocrine · doi:10.1007/s12020-019-01869-1 · Cited by 39
Molecular Basis of Primary Aldosteronism and Adrenal Cushing Syndrome
Vaduva, P., Bonnet-Serrano, F., & Bertherat, J. Y. (2020) · Journal of the Endocrine Society · doi:10.1210/jendso/bvaa075 · Cited by 35
Self-citationd’Alva, C. B., Abiven, G., Viallon, V., Groussin, L., Dugué, M. A., BERTAGNA, X. Y., & Bertherat, J. Y. (2008) · European Journal of Endocrinology · doi:10.1530/eje-08-0324 · Cited by 36
Self-citationAdrenocortical Cancer Treatment
Patalano, A., Brancato, V., & Mantero, F. (2009) · Hormone Research in Paediatrics · doi:10.1159/000178049 · Cited by 34
Classification of adrenal cortical tumors: What limits for the pathological approach?
Tissier, F. (2010) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2010.10.011 · Cited by 34
Bertherat, J. Y. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-3327 · Cited by 33
Self-citationHow to Differentiate Benign from Malignant Adrenocortical Tumors?
Viëtor, C. L., Creemers, S. G., van Kemenade, F. J., van Ginhoven, T. M., Hofland, L. J., & Feelders, R. A. (2021) · Cancers · doi:10.3390/cancers13174383 · Cited by 33
Rizk‐Rabin, M., Assié, G., René-Corail, F., Perlemoine, K., Hamzaoui, H., Tissier, F., Lieberherr, M., BERTAGNA, X. Y., Bertherat, J. Y., & Bouizar, Z. (2008) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-07-2924 · Cited by 30
Self-citationExpression of TIP30 Tumor Suppressor Gene Is Down-Regulated in Human Colorectal Carcinoma
Chen, X., Cao, X., Dong, W., Luo, S., Suo, Z., & Jin, Y. (2009) · Digestive Diseases and Sciences · doi:10.1007/s10620-009-0992-0 · Cited by 28
Chambre, C., McMurray, E. M., Baudry, C., Lataud, M., Guignat, L., Gaujoux, S., Lahlou, N., Guibourdenche, J., Tissier, F., Sibony, M., et al. (2015) · European Journal of Endocrinology · doi:10.1530/eje-15-0036 · Cited by 29
Self-citationCharacterization of the mTOR pathway in human normal adrenal and adrenocortical tumors
Martino, M. C. D., Feelders, R. A., de Herder, W. W., van Koetsveld, P. M., Dogan, F., Janssen, J. A. M. J. L., Waaijers, A. M., Pivonello, C., Lamberts, S. W. J., Colao, A., et al. (2014) · Endocrine Related Cancer · doi:10.1530/erc-13-0112 · Cited by 27
Molecular pathology of adrenal cortical tumors: Separating adenomas from carcinomas
Giordano, T. J. (2006) · Endocrine Pathology · doi:10.1007/s12022-006-0007-z · Cited by 27
Vincent-Dejean, C., Cazabat, L., Groussin, L., Perlemoine, K., Fumey, G., Tissier, F., BERTAGNA, X. Y., & Bertherat, J. Y. (2008) · European Journal of Endocrinology · doi:10.1530/eje-07-0819 · Cited by 26
Self-citationMenin Is Required for Optimal Processing of the MicroRNA let-7a
Gurung, B., Muhammad, A. B., & Hua, X. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.520692 · Cited by 26
Characteristics of Li‐Fraumeni syndrome in Japan: A review study by the special committee of JSHT
Funato, M., Tsunematsu, Y., Yamazaki, F., Tamura, C., Kumamoto, T., Takagi, M., Kato, S., Sugimura, H., & Tamura, K. (2021) · Cancer Science · doi:10.1111/cas.14919 · Cited by 24
The indeterminate adrenal mass in patients with cancer
Sahdev, A. (2007) · Cancer Imaging · doi:10.1102/1470-7330.2007.9017 · Cited by 24
The role of epithelial growth factors and insulin growth factors in the adrenal neoplasms
Angelousi, A. G., Kyriakopoulos, G., Ansari, N. N., Karageorgou, M., & Kassi, E. N. (2018) · Annals of Translational Medicine · doi:10.21037/atm.2018.05.52 · Cited by 25
Libé, R., Fratticci, A., Lahlou, N., Jornayvaz, F. R., Tissier, F., Louiset, E., Guibourdenche, J., Vieillefond, A., Zerbib, M., & Bertherat, J. Y. (2012) · Journal of Andrology · doi:10.2164/jandrol.111.013441 · Cited by 22
Self-citationChildhood Adrenocortical Tumours: a Review
Pereira, R. M., DeLacerda, L., Lacerda, H. M., Michalkiewicz, E., Sandrini, F., & Sandrini, R. (2006) · Hereditary Cancer in Clinical Practice · doi:10.1186/1897-4287-4-2-81 · Cited by 22
Precursor Lesions of the Adrenal Gland
van Nederveen, F. H., & de Krijger, R. R. (2007) · Pathobiology · doi:10.1159/000105811 · Cited by 22
Primary adrenal angiosarcoma and functioning adrenocortical adenoma: an exceptional combined tumor
Lussey‐Lepoutre, C., Rousseau, A., Ghuzlan, A. A., Amar, L., Hignette, C., Cioffi, A., Zinzindohoué, F., Leboulleux, S., & Plouin, P. (2011) · European Journal of Endocrinology · doi:10.1530/eje-11-0791 · Cited by 22
Syndromes de Cushing : physiopathologie, étiologie et principes thérapeutiques
Chabre, O. (2014) · La Presse Médicale · doi:10.1016/j.lpm.2014.02.001 · Cited by 21
Clinical and molecular prognostic factors in adrenocortical carcinoma
Libé, R. (2018) · Minerva Endocrinology · doi:10.23736/s0391-1977.18.02900-0 · Cited by 21
Genetic Alterations in Benign Adrenal Tumors
Pitsava, G., & Stratakis, C. A. (2022) · Biomedicines · doi:10.3390/biomedicines10051041 · Cited by 20
Novel Insights into the Genetics and Pathophysiology of Adrenocortical Tumors
Drougat, L., Omeiri, H., Lefèvre, L., & Ragazzon, B. (2015) · Frontiers in Endocrinology · doi:10.3389/fendo.2015.00096 · Cited by 19
mRNA and microRNA expression patterns in adrenocortical cancer.
Zsippai, A., Szabó, D. R., Szabó, P. M., Tömböl, Z., Bendes, M. R., Nagy, Z., Rácz, K., & Igaz, P. (2011) · PubMed Central · Cited by 19
Virilizing Adrenocortical Carcinoma Advancing to Central Precocious Puberty after Surgery
Kim, M. S., Yang, E. J., Cho, D. H., Hwang, P. H., & Lee, D. (2015) · Korean Journal of Family Medicine · doi:10.4082/kjfm.2015.36.3.150 · Cited by 18
Molecular markers of adrenocortical tumors
Jain, M., Rechache, N. S., & Kebebew, E. (2012) · Journal of Surgical Oncology · doi:10.1002/jso.23119 · Cited by 17
The clinical spectrum of adrenocortical hyperplasia
SCHTEINGART, D. E. (2012) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0b013e3283537ee9 · Cited by 15
Detection of polyomaviruses and herpesviruses in human adrenal tumors
Barzon, L., Trevisan, M., Masi, G., Pacenti, M., Sinigaglia, A., Macchi, V., Porzionato, A., Caro, R. D., Favia, G., Iacobone, M., et al. (2007) · Oncogene · doi:10.1038/sj.onc.1210699 · Cited by 15
The Role of gsp Mutations on the Development of Adrenocortical Tumors and Adrenal Hyperplasia
Fragoso, M. C. B. V., Wanichi, I. Q., Cavalcante, I. P., & Mariani, B. M. P. (2016) · Frontiers in Endocrinology · doi:10.3389/fendo.2016.00104 · Cited by 15
TIP30: A Novel Tumor-Suppressor Gene
Yu, X., Li, Z., & Wu, W. K. K. (2015) · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · doi:10.3727/096504015x14424348426116 · Cited by 14
Disorders of the adrenal cortex: Genetic and molecular aspects
Pitsava, G., Maria, A. G., & Faucz, F. R. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.931389 · Cited by 13
Igaz, P., Wiener, Z., Szabó, P. M., Falus, A., Gaillard, R. C., Horányi, J., Rácz, K., & Tulassay, Z. (2006) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2006.06.011 · Cited by 13
Androgen-Secreting Adrenal and Ovarian Neoplasms
PUGEAT, M. M., Raverot, G., Plotton, I., de la Perrière, A. B., Mirakian, P., Déchaud, H., Berger, N., & Peix, J. L. (2007) · Humana Press eBooks · doi:10.1007/978-1-59745-179-6_6 · Cited by 12
Adrenal mass in patients who underwent abdominal computed tomography examination
El-Menyar, A. A., Al-Sulaiti, M., Elgohary, H., Almalki, A., Asim, M., Tabeb, A., & Al-Thani, H. A. S. (2015) · North American Journal of Medical Sciences · doi:10.4103/1947-2714.157482 · Cited by 12
Ganeshan, D., Bhosale, P., & Kundra, V. (2012) · American Journal of Roentgenology · doi:10.2214/ajr.11.8282 · Cited by 12
Genetic information in the diagnosis and treatment of hypertension
Tomaszewski, M., Zimmerli, L., Charchar, F. J., & Dominiczak, A. F. (2006) · Current Hypertension Reports · doi:10.1007/s11906-006-0070-3 · Cited by 12
Martinerie, L., Bouligand, J., North, M.-O., Bertherat, J. Y., Assié, G., & Espiard, S. (2024) · Annales d Endocrinologie · doi:10.1016/j.ando.2024.01.005 · Cited by 11
Self-citationBulzico, D., Torres, D. C., Ferreira, G. M., Pires, B. R. B., de Faria, P. A. S., Hassan, R., Abdelhay, E. S. F. W., Vaisman, M., & Neto, L. V. (2017) · Endocrine Pathology · doi:10.1007/s12022-017-9482-7 · Cited by 11
Szyszka, P., Grossman, A. B., Díaz‐Cano, S. J., & Dorota Dworakowska, B. (2015) · Endokrynologia Polska · doi:10.5603/ep.a2016.0054 · Cited by 11
Ye, J., Qi, Y., Wang, W., Sun, F., Qin, W. D., Su, T., Zhou, W., Jiang, Y., Yuan, W.-Q., Cai, J.-F., et al. (2012) · Endocrine · doi:10.1007/s12020-012-9593-3 · Cited by 10
Pubertal outcome in a female with virilizing adrenocortical carcinoma
Breidbart, E., Cameo, T., Garvin, J. H., Hibshoosh, H. H., & Oberfield, S. E. (2016) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem-2015-0123 · Cited by 8
Pathogenesis of adrenocortical cancer
Szabó, D. R., Zsippai, A., Bendes, M. R., Tömböl, Z., Szabó, P. M., Rácz, K., & Igaz, P. (2010) · Orvosi Hetilap · doi:10.1556/oh.2010.28931 · Cited by 8
Genetics of adrenocortical disease
Bar-Lev, A., & Annes, J. P. (2012) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0b013e328352f013 · Cited by 8
Pusantisampan, T., Sangkhathat, S., Kayasut, K., Kanngurn, S., Jaruratanasirikul, S., Chotsampancharoen, T., & Kritsaneepaiboon, S. (2009) · Pediatric and Developmental Pathology · doi:10.2350/09-07-0683-cr.1 · Cited by 9
Adrenocortical Growth and Cancer
Lefèvre, L., Bertherat, J. Y., & Ragazzon, B. (2014) · Comprehensive physiology · doi:10.1002/cphy.c140010 · Cited by 12
Self-citationHsp90 inhibition in adrenocortical carcinoma: Limited drug synergism with mitotane
Sbiera, S., Kendl, S., Weigand, I., Sbiera, I., Faßnacht, M., & Kroiß, M. (2018) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2018.10.009 · Cited by 7
King-Spohn, K., & Pilarski, R. (2014) · Current Problems in Cancer · doi:10.1016/j.currproblcancer.2014.10.004 · Cited by 7
Pathogenesis of benign adrenocortical tumors
Vezzosi, D., Bertherat, J. Y., & Groussin, L. (2010) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2010.10.005 · Cited by 7
Self-citationAdrenocortical neoplasms in young children: age as a prognostic factor.
Ahmed, A. A. (2009) · PubMed · Cited by 7
Elfiky, A. A. (2015) · Surgical pathology clinics · doi:10.1016/j.path.2015.07.002 · Cited by 7
Hunt, K. S., Ray, J. A., & Jeter, J. (2013) · Springer eBooks · doi:10.1007/978-3-642-38983-2_5 · Cited by 6
p53 Testing for Li‐Fraumeni and Li‐Fraumeni‐Like Syndromes
Hagman, K. D. F., Fong, C., Buzin, C. H., Sommer, S. S., & Saldivar, J. (2008) · Current Protocols in Human Genetics · doi:10.1002/0471142905.hg1010s57 · Cited by 6
Genomic medicine for cancer diagnosis
Gordon, B. L., Finnerty, B. M., Aronova, A., & Fahey, T. J. (2014) · Journal of Surgical Oncology · doi:10.1002/jso.23778 · Cited by 5
Metadata
- Authors
- Libé, R., & Bertherat, J.
- Venue
- European Journal of Endocrinology
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-10
- Volume
- 153
- Issue
- 4
- Pages
- 477-487
- ISSN
- 0804-4643 (ISSN-L)
- 1479-683X
- OpenAlex
- W2171162119
- Cited by
- 168
- References
- 106
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 1 · 2022: 3 · 2021: 4 · 2020: 3 · 2019: 6 · 2018: 8 · 2017: 5 · 2016: 8 · 2015: 11 · 2014: 14 · 2013: 6 · 2012: 13
- FWCI
- 2.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Endocrinology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Chromatin Remodeling and Cancer
- Keywords
- adrenocortical tumors, adrenocortical carcinoma, adrenal adenoma, Li-Fraumeni syndrome, TP53, Beckwith-Wiedemann syndrome, multiple endocrine neoplasia type 1, Carney complex, PRKAR1A mutation, Cushing's syndrome, primary pigmented nodular adrenocortical disease, loss of heterozygosity, 17p13, 11p15, ACTH receptor, adrenal nodular hyperplasia, congenital adrenal hyperplasia, glucocorticoid-remediable aldosteronism, hereditary cancer, somatic mutations
- MeSH terms
- Adrenal Cortex Neoplasms, Humans, Molecular Biology
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review