The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Environmental anti-androgens and male reproductive health: focus on phthalates and testicular dysgenesis syndrome
Open accessAbstract
The amount of research into endocrine disruption has exploded over the past decade and a re-evaluation of the state of research in this area is timely. There are debates about whether human male reproductive health is really declining and whether endocrine disrupting chemicals play any role in the perceived decline. Most data currently conclude that there are wide geographical variations in semen quality and in the incidence of testicular cancer, cryptorchidism and hypospadias. This review aims to give a brief overview of the issues surrounding the perceived decline in human male reproductive health and the importance of the hormonal environment for the development of the testis and reproductive tract. The consequences for the male reproductive tract of abnormal androgen levels or action are discussed with reference to environmental anti-androgenic compounds. The in vivo data on several anti-androgenic compounds that have been administered to pregnant rodents during the period of male reproductive tract development are assessed with attention to the effects on the male offspring. Finally, the data on in utero phthalate administration are discussed in detail to illustrate the similarities between the effects of some phthalate esters and the human male reproductive tract disorders which comprise testicular dysgenesis syndrome (TDS).
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Cites
Gray, L. E. (2000) · Toxicological Sciences · doi:10.1093/toxsci/58.2.350 · Cited by 1,084
Levels of Seven Urinary Phthalate Metabolites in a Human Reference Population
Blount, B. C., Silva, M. J., Caudill, S. P., Needham, L. L., Pirkle, J. L., Sampson, E. J., Lucier, G. W., Jackson, R. J., & Brock, J. W. (2000) · Environmental Health Perspectives · doi:10.1289/ehp.00108979 · Cited by 634
Mylchreest, E., Sar, M., Cattley, R. C., & Foster, P. M. D. (1999) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1999.8643 · Cited by 440
Male Reproductive Health and Environmental Xenoestrogens
Toppari, J., Larsen, J. C., Christiansen, P., Giwercman, A., Grandjean, P., Guillette, L. J., Jegou, B., Jensen, T. K., Jouannet, P., Keiding, N., et al. (1996) · Environmental Health Perspectives · doi:10.2307/3432709 · Cited by 348
High frequency of sub-optimal semen quality in an unselected population of young men
Andersen, A. G. (2000) · Human Reproduction · doi:10.1093/humrep/15.2.366 · Cited by 323
Geographic differences in semen quality of fertile U.S. males.
Swan, S. H., Brazil, C., Drobnis, E. Z., Liu, F., Kruse, R. L., Hatch, M., Redmon, J. B., Wang, C., Overstreet, J. W., & Study For Future Families Research Group (2003) · Environmental Health Perspectives · doi:10.1289/ehp.5927 · Cited by 297
Cited by
Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility
Anway, M. D., Cupp, A. S., Uzumcu, M., & Skinner, M. K. (2005) · Science · doi:10.1126/science.1108190 · Cited by 2,563
Decrease in anogenital distance among male infants with prenatal phthalate exposure
Swan, S. H., Main, K. M., Liu, F., Stewart, S. L., Kruse, R. L., Calafat, A. M., Mao, C. S., Redmon, J. B., Ternand, C. L., Sullivan, S., et al. (2005) · Environmental Health Perspectives · doi:10.1289/ehp.8100 · Cited by 1,586
The pros and cons of phytoestrogens
Patisaul, H. B., & Jefferson, W. (2010) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.03.003 · Cited by 746
Stahlhut, R. W., van Wijngaarden, E., Dye, T. D., Cook, S., & Swan, S. H. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.9882 · Cited by 646
Koch, H. M., Preuss, R., & Angerer, J. (2006) · International Journal of Andrology · doi:10.1111/j.1365-2605.2005.00607.x · Cited by 590
Metadata
- Authors
- Fisher, J. S.
- Venue
- Reproduction
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-03-01
- Volume
- 127
- Issue
- 3
- Pages
- 305-315
- ISSN
- 1470-1626 (ISSN-L)
- 1741-7899
- OpenAlex
- W2040462127
- Cited by
- 427
- References
- 6
- FWCI
- 23.86
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
