The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
The Use of Low Level Laser Therapy (LLLT) For Musculoskeletal Pain
Open accessAbstract
Pain is the most common reason for physician consultation in the United States. One out of three Americans is affected by chronic pain annually. The number one reason for missed work or school days is musculoskeletal pain. Currently accepted therapies consist of non-steroidal anti-inflammatory drugs, steroid injections, opiate pain medications and surgery, each of which carries their own specific risk profiles. What is needed are effective treatments for pain which have an acceptably low risk-profile. For over forty years, low level laser (light) therapy (LLLT) and LED (light emitting diode) therapy (also known as photobiomodulation) has been shown to reduce inflammation and edema, induce analgesia, and promote healing in a range of musculoskeletal pathologies. The purpose of this paper is to review the use of LLLT for pain, the biochemical mechanisms of action, the dose response curves, and how LLLT may be employed by orthopedic surgeons to improve outcomes and reduce adverse events. With the predicted epidemic of chronic pain in developed countries, it is imperative to validate cost-effective and safe techniques for managing painful conditions which would allow people to live active and productive lives. Moreover the acceptance of LLLT (which is currently being used by many specialties around the world) into the armamentarium of the American health care provider would allow for additional treatment options for patients. A new cost-effective therapy for pain could elevate quality of life while reducing financial strains.
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Cites
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MAIMAN, T. H. (1960) · Nature · doi:10.1038/187493a0 · Cited by 5,121
The Economic Costs of Pain in the United States
Gaskin, D. J., & Richard, P. (2012) · The Journal of Pain · doi:10.1016/j.jpain.2012.03.009 · Cited by 2,359
The Nuts and Bolts of Low-level Laser (Light) Therapy
Chung, H., Dai, T., Sharma, S. K., Huang, Y.-Y., Carroll, J. D., & Hamblin, M. R. (2012) · Annals of Biomedical Engineering · doi:10.1007/s10439-011-0454-7 · Cited by 1,624
The prevalence of chronic pain in United States adults: Results of an Internet-based survey
Johannes, C. B., Le, T. K., Zhou, X., Johnston, J. A., & Dworkin, R. H. (2010) · The Journal of Pain · doi:10.1016/j.jpain.2010.07.002 · Cited by 1,252 · cited 1×
“Musculoskeletal pain affects 116 million Americans annually at a cost of $635 billion a year in medical bills, lost productivity and missed work or school [1,2].”
BackgroundBiphasic Dose Response in Low Level Light Therapy
Huang, Y.-Y., Chen, A. C.-H., Carroll, J. D., & Hamblin, M. R. (2009) · Dose-Response · doi:10.2203/dose-response.09-027.hamblin · Cited by 1,162
Biphasic Dose Response in Low Level Light Therapy – an Update
Huang, Y.-Y., Sharma, S. K., Carroll, J., & Hamblin, M. R. (2011) · Dose-Response · doi:10.2203/dose-response.11-009.hamblin · Cited by 854
Photobiomodulation Directly Benefits Primary Neurons Functionally Inactivated by Toxins
Wong-Riley, M. T. T., Liang, H. L., Eells, J. T., Chance, B., Henry, M. M., Buchmann, E., Kane, M., & Whelan, H. T. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m409650200 · Cited by 629
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Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase
Brown, G. C. (1995) · FEBS Letters · doi:10.1016/0014-5793(95)00763-y · Cited by 540
Chen, A. C.-H., Arany, P. R., Huang, Y.-Y., Tomkinson, E. M., Sharma, S. K., Kharkwal, G. B., Saleem, T., Mooney, D., Yull, F. E., Blackwell, T. S., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022453 · Cited by 522
Metadata
- Authors
- B Cotler, H.
- Venue
- MOJ Orthopedics & Rheumatology
- Publisher
- MedCrave Group, LLC
- Published
- 2015-06-09
- Volume
- 2
- Issue
- 5
- ISSN
- 2374-6939 (ISSN-L)
- OpenAlex
- W1898734286
- Cited by
- 379
- References
- 55
- FWCI
- 10.35
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.