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Cited by 137Substance Abuse Treatment and OutcomesAttention Deficit Hyperactivity DisorderChild and Adolescent Psychosocial and Emotional Development

The DOI matches its Crossref record; 76 of the 77 references it cites were found in a registry or an index.

Behavioral Predictors of Substance-Use Initiation in Adolescents With and Without Attention-Deficit/Hyperactivity Disorder

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Ernst, Monique, Luckenbaugh, David A., Moolchan, Eric T., Leff, Michelle K., Allen, Rachel, Eshel, Neir, London, Edythe D., Kimes, Alane·2006·Pediatrics
DOI 10.1542/peds.2005-0704
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Abstract

OBJECTIVE. Our goal was to examine substance-use initiation in healthy adolescents and in adolescents who have been diagnosed with attention-deficit/hyperactivity disorder. METHODS. Seventy-eight adolescents (28 healthy and 50 with attention-deficit/hyperactivity disorder) participated in an ongoing longitudinal study of predictors of substance use. The substances most commonly reported were tobacco, alcohol, and marijuana. Aggression, conduct problems, hyperactivity, impulsivity, inattention, anxiety/depression, social difficulties, and somatic complaints were assessed at study entry and tested as predictors for later substance use. RESULTS. With an average of 4 years into the study, 37 adolescents had not used any substances, 41 had experimented with at least 1 substance, and 29 experimented with >1 substance. Psychiatric diagnoses (attention-deficit/hyperactivity disorder, attention-deficit/hyperactivity disorder and conduct disorder, and attention-deficit/hyperactivity disorder and depression/anxiety) did not influence reports of substance use. Distinct behavioral measures collected at study entry predicted use of different substances. In a multivariate analysis, aggression had the greatest association with tobacco smoking and marijuana use. Impulsivity was associated with alcohol use. Severity of drug exposure, indexed by the number of substances used, was predicted by aggression. CONCLUSIONS. This 4-year longitudinal study captured the onset of substance use, not abuse. Behavioral predictors differed with the type of substance used. These behavioral characteristics may raise suspicion among pediatricians for enhanced risk for substance-use initiation.

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Metadata

Authors
Ernst, M., Luckenbaugh, D. A., Moolchan, E. T., Leff, M. K., Allen, R., Eshel, N., London, E. D., & Kimes, A.
Affiliations
  • Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, Maryland
  • National Institutes of Health (US)
  • National Institute on Drug Abuse (US)
  • University of California, Los Angeles (US)
ORCID
Venue
Pediatrics
Publisher
American Academy of Pediatrics (AAP)
Published
2006-06-01
Volume
117
Issue
6
Pages
2030-2039
ISSN
  • 0031-4005 (ISSN-L)
  • 1098-4275
DOI
10.1542/peds.2005-0704
OpenAlex
W1975368442
Cited by
137
References
77
Citations by year
2026: 1 · 2025: 1 · 2024: 4 · 2023: 7 · 2022: 7 · 2021: 3 · 2020: 3 · 2019: 4 · 2018: 2 · 2017: 3 · 2016: 5 · 2015: 9 · 2014: 9 · 2013: 10 · 2012: 16
FWCI
7.96
Type
journal article
Language
en
Open access
Locations
  • PEDIATRICS (publishedVersion)
  • PubMed (publishedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
  • UCL Discovery (University College London) (submittedVersion)
Funders
National Institutes of Health
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Keywords
substance use initiation, attention deficit hyperactivity disorder, adolescents, aggression, impulsivity, smoking, alcohol consumption, cannabis use, conduct disorder, anxiety and depression, behavioral predictors
MeSH terms
Adolescent, Adolescent Behavior, Attention Deficit Disorder with Hyperactivity, Child, Female, Humans, Longitudinal Studies, Male, Substance-Related Disorders

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