Consensus Statement on Management of Intersex Disorders
Abstract
The birth of an intersex child prompts a long-term management strategy that involves a myriad of professionals working with the family. There has been progress in diagnosis, surgical techniques, understanding psychosocial issues and in recognizing and accepting the place of patient advocacy. The Lawson Wilkins Paediatric Endocrine Society (LWPES) and the European Society for Paediatric Endocrinology (ESPE) considered it timely to review the management of intersex disorders from a broad perspective, to review data on longer term outcome and to formulate proposals for future studies. The methodology comprised establishing a number of working groups whose membership was drawn from 50 international experts in the field. The groups prepared prior written responses to a defined set of questions resulting from an evidence based review of the literature. At a subsequent gathering of participants, a framework for a consensus document was agreed. This paper constitutes its final form.
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Increased psychiatric symptomatology in both sexes with CAH mirrors observations for a wide range of chronic medical conditions.
“The mental health of patients with CAH is another example; although most studies focus on females, increased psychiatric symptomatology in both sexes mirrors observations for a wide range of chronic medical conditions (547,594-597).”
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- Authors
- Lee, P. A., Houk, C. P., Ahmed, S. F., Hughes, I. A., & in collaboration with the participants in the International Consensus Conference on Intersex organized by the Lawson Wilkins Pediatric Endocrine Society and the European Society for Paediatric Endocrinology
- Affiliations
- Pennsylvania State University (US)
- Mercer University (US)
- Royal Hospital for Children (GB)
- University of Cambridge (GB)
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 2006-08-01
- Volume
- 118
- Issue
- 2
- Pages
- e488-e500
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W2156526029
- Cited by
- 2,324
- References
- 5
- Citations by year
- 2026: 52 · 2025: 70 · 2024: 143 · 2023: 152 · 2022: 124 · 2021: 147 · 2020: 154 · 2019: 154 · 2018: 119 · 2017: 125 · 2016: 129 · 2015: 137 · 2014: 123 · 2013: 126 · 2012: 121
- FWCI
- 30.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- PEDIATRICS (publishedVersion)
- PubMed (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Pure Amsterdam UMC (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- Pfizer
- European Society for Paediatric Endocrinology
- European Society of Endocrinology
- Pediatric Endocrine Society
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Sexual Differentiation and Disorders
- Health Sciences › Medicine › Urology › Urological Disorders and Treatments
- Social Sciences › Psychology › Social Psychology › LGBTQ Health, Identity, and Policy
- Keywords
- intersex disorders, long-term outcomes, surgical management, psychosocial problems, patient advocacy, multidisciplinary care, gender assignment, pediatric endocrinology
- MeSH terms
- Attitude to Health, Combined Modality Therapy, Counseling, Female, Forecasting, Gender Identity, Gonadal Dysgenesis, 46,XY, Humans, Infant, Newborn, Male, Neoplasms, Germ Cell and Embryonal, Terminology as Topic, Parents, Phenotype, Psychology, Sexual Behavior, Disorders of Sex Development, Gonadal Steroid Hormones, Treatment Outcome, Case Management, Genetic Predisposition to Disease
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