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Cited by 162Fibromyalgia and Chronic Fatigue Syndrome ResearchLong-Term Effects of COVID-19Cardiovascular Syncope and Autonomic Disorders

The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.

Adolescent Chronic Fatigue Syndrome: Prevalence, Incidence, and Morbidity

Nijhof, Sanne L., Maijer, Kimberley, Bleijenberg, Gijs, Uiterwaal, Cuno S. P. M., Kimpen, Jan L. L., van de Putte, Elise M.·2011·Pediatrics
DOI 10.1542/peds.2010-1147
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Abstract

OBJECTIVE: To determine nationwide general practitioner (GP)-diagnosed prevalence and pediatrician–diagnosed incidence rates of adolescent chronic fatigue syndrome (CFS), and to assess CFS morbidity. DESIGN AND SETTING: We collected data from a cross-sectional national sample among GPs and prospective registration of new patients with CFS in all pediatric hospital departments in the Netherlands. PATIENTS AND METHODS: Study participants were adolescents aged 10 to 18 years. A representative sample of GPs completed questionnaires on the prevalence of CFS in their adolescent patients. Pediatric hospital departments prospectively reported new cases of CFS in adolescent patients. For every new reported case, a questionnaire was sent to the reporting pediatrician and the reported patient to assess CFS morbidity. Prevalence was estimated through the data from GP questionnaires and incidence was estimated on the basis of cases newly reported by pediatricians from January to December 2008. RESULTS: Prevalence was calculated as 111 per 100 000 adolescents and incidence as 12 per 100 000 adolescents per year. Of newly reported patients with CFS, 91% scored at or above cutoff points for severe fatigue and 93% at or above the cutoff points for physical impairment. Forty-five percent of patients with CFS reported >50% school absence during the previous 6 months. CONCLUSIONS: Clinically diagnosed incidence and prevalence rates show that adolescent CFS is uncommon compared with chronic fatigue. The primary adverse impact of CFS is extreme disability associated with considerable school absence.

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Metadata

Authors
Nijhof, S. L., Maijer, K., Bleijenberg, G., Uiterwaal, C. S. P. M., Kimpen, J. L. L., & van de Putte, E. M.
Affiliations
  • University Medical Center Utrecht (NL)
  • Wilhelmina Children's Hospital (NL)
  • Radboud University Medical Center (NL)
  • Department of Pediatrics, Wilhelmina Children's Hospital, and
ORCID
Venue
Pediatrics
Publisher
American Academy of Pediatrics (AAP)
Published
2011-05-01
Volume
127
Issue
5
Pages
e1169-e1175
ISSN
  • 0031-4005 (ISSN-L)
  • 1098-4275
DOI
10.1542/peds.2010-1147
OpenAlex
W2132523553
Cited by
162
References
26
Citations by year
2026: 1 · 2025: 4 · 2024: 7 · 2023: 4 · 2022: 12 · 2021: 8 · 2020: 12 · 2019: 18 · 2018: 14 · 2017: 19 · 2016: 12 · 2015: 12 · 2014: 14 · 2013: 15 · 2012: 10
FWCI
8.53
Type
journal article
Language
en
Open access
closed
Locations
  • PEDIATRICS (publishedVersion)
  • PubMed (publishedVersion)
  • Radboud Repository (Radboud University) (submittedVersion)
Funders
Centers for Disease Control and Prevention
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
  • Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Syncope and Autonomic Disorders
Keywords
chronic fatigue syndrome, adolescents, prevalence, incidence, morbidity, school absenteeism, physical impairment, disability, general practitioners
MeSH terms
Adolescent, Child, Chronic Disease, Cross-Sectional Studies, Fatigue, Female, Humans, Male, Netherlands, Pediatrics, Surveys and Questionnaires, Severity of Illness Index, Fatigue Syndrome, Chronic, Incidence, Prevalence, Sex Distribution, General Practice

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