ADHD Diagnosis and Treatment Guidelines: A Historical Perspective
Abstract
Attention-deficit/hyperactivity disorder (ADHD) is the most common behavioral condition and the second most common chronic illness in children. The observance of specific behaviors in multiple settings have remained the most successful method for diagnosing the condition, and although there are differences in specific areas of the brain, and a high heritability estimate (∼76%), they are not diagnostically specific. Medications, and particularly stimulant medication, have undergone rigorous studies to document their efficacy dating back to the 1970s. Likewise, behavioral interventions in the form of parent training and classroom programs have demonstrated robust efficacy during the same time period. Both medication and behavioral interventions are symptomatic treatments. The availability of only symptomatic treatments places ADHD in the same category as other chronic conditions such as diabetes and asthma. Successful treatment of most individuals requires ongoing adherence to the therapy. Improved communication between patients and their families, primary and mental health providers, and school personnel is necessary for effective ADHD treatment. Further enhancement of electronic systems to facilitate family, school, and provider communication can improve monitoring of ADHD symptoms and functional performance. The American Academy of Pediatrics ADHD guidelines were initially developed to help primary care clinicians address the needs of their patients with ADHD and were further refined with the second revision in 2019.
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Research indicates that α2-adrenergic agonists have a lower effect size than psychostimulants for treating symptoms of ADHD in non-autistic children and adolescents.
“Research indicates that α2-adrenergic agonists have a lower effect size than psychostimulants for treating symptoms of ADHD in non-autistic children and adolescents [77].”
From Pharmacological treatment in autism: a proposal for guidelines on common co-occurring psychiatric symptoms (2025) · cites this paper as [77]
The AAP Clinical Practice Guideline on ADHD identifies parent-training behavior management as the first-line approach for preschool-aged children and medication management in conjunction with PTBM and behavioral classroom interventions for youth ages six years or older.
“The American Academy of Pediatrics (AAP) Clinical Practice Guideline on ADHD in the general population identifies parent-training behavior management (PTBM) as the first-line approach for preschool-aged children and medication management in conjunction with PTBM and behavioral classroom interventions for youth ages six years or older [77].”
From Pharmacological treatment in autism: a proposal for guidelines on common co-occurring psychiatric symptoms (2025) · cites this paper as [77]
Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2022) · doi:10.1176/appi.books.9780890425787 · Cited by 23,476 · see citing works
Wolraich, M. L., Hagan, J. F., Allan, C., Chan, E., Davison, D., Earls, M., Evans, S. W., Flinn, S. K., Froehlich, T., Frost, J., et al. (2019) · Pediatrics · doi:10.1542/peds.2019-2528 · Cited by 1,410 · see citing works
Self-citationDanielson, M. L., Bitsko, R. H., Ghandour, R. M., Holbrook, J. R., Kogan, M. D., & Blumberg, S. J. (2018) · Journal of Clinical Child & Adolescent Psychology · doi:10.1080/15374416.2017.1417860 · Cited by 1,181 · see citing works
THE BEHAVIOR OF CHILDREN RECEIVING BENZEDRINE
Bradley, C. (1937) · American Journal of Psychiatry · doi:10.1176/ajp.94.3.577 · Cited by 1,035 · see citing works
del Campo, N., Chamberlain, S. R., Sahakian, B. J., & Robbins, T. W. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.02.036 · Cited by 685 · see citing works
JENSEN, P. S., HINSHAW, S. P., SWANSON, J. M., GREENHILL, L. L., CONNERS, C. K., ARNOLD, L. E., ABIKOFF, H. B., ELLIOTT, G., HECHTMAN, L., HOZA, B., et al. (2001) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200102000-00008 · Cited by 591 · see citing works
Caye, A., Spadini, A. V., Karam, R. G., Grevet, E. H., Rovaris, D. L., Bau, C. H. D., Rohde, L. A., & Kieling, C. (2016) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-016-0831-8 · Cited by 210 · see citing works
Evaluation of a school-based treatment program for young adolescents with ADHD.
Evans, S. W., Langberg, J. M., Schultz, B. K., Vaughn, A., Altaye, M., Marshall, S. A., & Zoromski, A. K. (2016) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000057 · Cited by 155 · see citing works
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Danielson, M. L., Claussen, A. H., Bitsko, R. H., Katz, S. M., Newsome, K., Blumberg, S. J., Kogan, M. D., & Ghandour, R. (2024) · Journal of Clinical Child & Adolescent Psychology · doi:10.1080/15374416.2024.2335625 · Cited by 347 · see citing works
Coghill, D., Banaschewski, T., Cortese, S., Asherson, P., Brandeis, D., Buitelaar, J., Daley, D., Danckaerts, M., Dittmann, R. W., Doepfner, M., et al. (2023) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-021-01871-x · Cited by 180 · see citing works
Manter, M. A., Birtwell, K. B., Bath, J., Friedman, N. D. B., Keary, C. J., Neumeyer, A. M., Palumbo, M. L., Thom, R. P., Stonestreet, E., Brooks, H., et al. (2025) · BMC Medicine · doi:10.1186/s12916-024-03814-0 · Cited by 51 · see citing works
“…Practice Guideline on ADHD in the general population identifies parent-training behavior management (PTBM) as the first-line approach for preschool-aged children and medication management in conjunction with PTBM and behavioral classroom interventions for youth ages six years or older [77].”
Robotic Technologies in ADHD Care: Literature Review
Berrezueta-Guzman, J., Robles-Bykbaev, V. E., Pau, I., Pesantez-Aviles, F., & Martin-Ruiz, M.-L. (2022) · IEEE Access · doi:10.1109/access.2021.3137082 · Cited by 38 · see citing works
- Authors
- Wolraich, M. L., Chan, E., Froehlich, T., Lynch, R. L., Bax, A., Redwine, S. T., Ihyembe, D., & Hagan, J. F.
- Affiliations
- University of Oklahoma Health Sciences Center (US)
- Boston Children's Hospital (US)
- Cincinnati Children's Hospital Medical Center (US)
- Mayo Clinic (US)
- University of Vermont (US)
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 2019-10-01
- Volume
- 144
- Issue
- 4
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W2977387298
- Cited by
- 152
- References
- 8
- Citations by year
- 2026: 11 · 2025: 22 · 2024: 34 · 2023: 27 · 2022: 26 · 2021: 26 · 2020: 6
- FWCI
- 11.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- PEDIATRICS (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Psychology › Developmental and Educational Psychology › Behavioral and Psychological Studies
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- attention deficit hyperactivity disorder, ADHD diagnosis, ADHD treatment, stimulant medication, behavioral interventions, parent training, classroom program, American Academy of Pediatrics guidelines, heritability, children with chronic illness, electronic health systems
- MeSH terms
- Central Nervous System Stimulants, Attention Deficit Disorder with Hyperactivity, Child, Child Behavior, Humans, Quality of Health Care, Software, Parenting, Practice Guidelines as Topic, Decision Support Systems, Clinical, Diagnostic and Statistical Manual of Mental Disorders, History, 20th Century, History, 21st Century, Quality Improvement, Transition to Adult Care
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