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Cited by 205Attention Deficit Hyperactivity DisorderBehavioral and Psychological StudiesDevelopmental and Educational Neuropsychology

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Time-Response Analysis of the Effect of Stimulant Medication on the Learning Ability of Children Referred for Hyperactivity

Swanson, James, Kinsbourne, Marcel, Roberts, Wendy, Zucker, Kenneth·1978·PEDIATRICS
DOI 10.1542/peds.61.1.21
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Abstract

This report introduces a method for obtaining behavioral time-response information for a short-acting psychotropic drug (methylphenidate [Ritalin]) that is widely used to treat behaviorally hyperactive children. We used a laboratory learning task to document that between one and two hours after the administration of a single dose of methylphenidate, the drug exerts its maximum effect on performance in a learning task in the laboratory. This effect on cognitive performance dissipates within the same day. This rapid and transient effect of methylphenidate makes it possible to classify patients in a single day into those who respond favorably and those who respond adversely to the drug in terms of its effect on cognitive behavior.

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Crossref · 10.1542/peds.61.1.21

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Metadata

Authors
Swanson, J., Kinsbourne, M., Roberts, W., & Zucker, K.
Affiliations
Hospital for Sick Children (CA)
ORCID
Venue
PEDIATRICS
Publisher
American Academy of Pediatrics (AAP)
Published
1978-01-01
Volume
61
Issue
1
Pages
21-29
ISSN
  • 0031-4005 (ISSN-L)
  • 1098-4275
DOI
10.1542/peds.61.1.21
OpenAlex
W1512135897
Cited by
205
References
18
Citations by year
2022: 1 · 2016: 1 · 2015: 2 · 2014: 2 · 2012: 5
FWCI
10.31
Type
journal article
Language
en
Open access
closed
Locations
  • PEDIATRICS (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Social Sciences › Psychology › Developmental and Educational Psychology › Behavioral and Psychological Studies
  • Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Developmental and Educational Neuropsychology
Keywords
methylphenidate, hyperactivity, stimulant medication, time response analysis, cognitive performance, learning ability, children, drug response variability, pharmacokinetics
MeSH terms
Association Learning, Attention Deficit Disorder with Hyperactivity, Child, Clinical Trials as Topic, Cognition, Female, Humans, Learning, Male, Methylphenidate, Prognosis, Psychomotor Performance, Time Factors

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