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Hospitalization Rates and Characteristics of Children Aged <18 Years Hospitalized with Laboratory-Confirmed COVID-19 — COVID-NET, 14 States, March 1–July 25, 2020
Open accessAbstract
Most reported cases of coronavirus disease 2019 (COVID-19) in children aged <18 years appear to be asymptomatic or mild (1). Less is known about severe COVID-19 illness requiring hospitalization in children. During March 1-July 25, 2020, 576 pediatric COVID-19 cases were reported to the COVID-19-Associated Hospitalization Surveillance Network (COVID-NET), a population-based surveillance system that collects data on laboratory-confirmed COVID-19-associated hospitalizations in 14 states (2,3). Based on these data, the cumulative COVID-19-associated hospitalization rate among children aged <18 years during March 1-July 25, 2020, was 8.0 per 100,000 population, with the highest rate among children aged <2 years (24.8). During March 21-July 25, weekly hospitalization rates steadily increased among children (from 0.1 to 0.4 per 100,000, with a weekly high of 0.7 per 100,000). Overall, Hispanic or Latino (Hispanic) and non-Hispanic black (black) children had higher cumulative rates of COVID-19-associated hospitalizations (16.4 and 10.5 per 100,000, respectively) than did non-Hispanic white (white) children (2.1). Among 208 (36.1%) hospitalized children with complete medical chart reviews, 69 (33.2%) were admitted to an intensive care unit (ICU); 12 of 207 (5.8%) required invasive mechanical ventilation, and one patient died during hospitalization. Although the cumulative rate of pediatric COVID-19-associated hospitalization remains low (8.0 per 100,000 population) compared with that among adults (164.5),* weekly rates increased during the surveillance period, and one in three hospitalized children were admitted to the ICU, similar to the proportion among adults. Continued tracking of SARS-CoV-2 infections among children is important to characterize morbidity and mortality. Reinforcement of prevention efforts is essential in congregate settings that serve children, including childcare centers and schools.
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Cites
Prevalence of Obesity Among Adults and Youth: United States, 2015-2016.
Hales, C. M., Carroll, M. D., Fryar, C. D., & Ogden, C. L. (2017) · PubMed · Cited by 3,884
Garg, S., Kim, L., Whitaker, M., O’Halloran, A., Cummings, C., Holstein, R., Prill, M., Chai, S. J., Kirley, P. D., Alden, N. B., et al. (2020) · MMWR. Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm6915e3 · Cited by 2,335
Self-citationMultisystem Inflammatory Syndrome in Children in New York State
Dufort, E. M., Koumans, E. H., Chow, E. J., Rosenthal, E. M., Muse, A., Rowlands, J., Barranco, M. A., Maxted, A. M., Rosenberg, E. S., Easton, D., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2021756 · Cited by 1,350
Self-citationKim, L., Garg, S., O’Halloran, A., Whitaker, M., Pham, H., Anderson, E. J., Armistead, I., Bennett, N. M., Billing, L., Como-Sabetti, K., et al. (2021) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa1012 · Cited by 649
Self-citationZachariah, P., Johnson, C. L., Halabi, K. C., Ahn, D., Sen, A. I., Fischer, A., Banker, S. L., Giordano, M., Manice, C. S., Diamond, R., et al. (2020) · JAMA Pediatrics · doi:10.1001/jamapediatrics.2020.2430 · Cited by 511
Proportion of asymptomatic coronavirus disease 2019: A systematic review and meta‐analysis
He, J., Guo, Y., Mao, R., & Zhang, J. (2021) · Journal of Medical Virology · doi:10.1002/jmv.26326 · Cited by 383
Chao, J. Y., Derespina, K. R., Herold, B. C., Goldman, D. L., Aldrich, M., Weingarten, J., Ushay, H. M., Cabana, M. D., & Medar, S. S. (2020) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2020.05.006 · Cited by 336
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Cited by
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Dougan, M., Nirula, A., Azizad, M., Mocherla, B., Gottlieb, R. L., Chen, P., Hebert, C., Perry, R., Boscia, J., Heller, B., et al. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2102685 · Cited by 663
Evaluation of the BNT162b2 Covid-19 Vaccine in Children 5 to 11 Years of Age
Walter, E. B., Talaat, K. R., Sabharwal, C., Gurtman, A., Lockhart, S., Paulsen, G. C., Barnett, E. D., Muñoz, F. M., Maldonado, Y., Pahud, B. A., et al. (2022) · New England Journal of Medicine · doi:10.1056/nejmoa2116298 · Cited by 593
Evaluation of mRNA-1273 SARS-CoV-2 vaccine in adolescents
Ali, K., Berman, G., Zhou, H., Deng, W., Faughnan, V., Coronado-Voges, M., Ding, B., Dooley, J., Girard, B., Hillebrand, W., et al. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2109522 · Cited by 377
Delahoy, M. J., Ujamaa, D., Whitaker, M., O'Halloran, A., Anglin, O., Burns, E., Cummings, C., Holstein, R., Kambhampati, A. K., Milucky, J., et al. (2021) · MMWR. Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm7036e2 · Cited by 273
Self-citationSoltan, A. A. S., Kouchaki, S., Zhu, T., Kiyasseh, D., Taylor, T., Hussain, Z. B., Peto, T., Brent, A. J., Eyre, D. W., & Clifton, D. A. (2021) · The Lancet Digital Health · doi:10.1016/s2589-7500(20)30274-0 · Cited by 150
Metadata
- Authors
- Kim, L., Whitaker, M., O’Halloran, A., Kambhampati, A., Chai, S. J., Reingold, A., Armistead, I., Kawasaki, B., Meek, J., Yousey-Hindes, K., Anderson, E. J., Openo, K. P., Weigel, A., Ryan, P., Monroe, M. L., Fox, K., Kim, S., Lynfield, R., Bye, E., Shrum Davis, S., Smelser, C., Barney, G., Spina, N. L., Bennett, N. M., Felsen, C. B., Billing, L. M., Shiltz, J., Sutton, M., West, N., Talbot, H. K., Schaffner, W., Risk, I., Price, A., Brammer, L., Fry, A. M., Hall, A. J., Langley, G. E., Garg, S., COVID-NET Surveillance Team, COVID-NET Surveillance Team, Coates, A., Daily Kirley, P., Libby, T., Roland, J., Alden, N., Herlihy, R., McLafferty, S., Clogher, P., Kayalioglu, H., Maslar, A., Misiorski, A., Niccolai, L., Olson, D., Parisi, C., Fawcett, E., Gretzinger, S., Lengacher, K., Williams, J., Blythe, D., Brooks, A., Park, R., Wilson, M., Como-Sabetti, K., Danila, R., Cline, C., Angeles, K., Eisenberg, N., Flores, K., Habrun, C., Hancock, E., Khanlian, S., Novi, M., Phipps, E., Salazar-Sanchez, Y., Dufort, E., Muse, A., Bushey, S., Gaitan, M., Kurtz, R., Owusu-Dommey, A., Snyder, L., Michaelis, K., Seeley, K., Markus, T., Chatelain, R., George, A., Hill, M., McCullough, L., Spencer, M., Swain, A., McCaffrey, K., Holstein, R., Meador, S., & Wortham, J.
- Venue
- MMWR. Morbidity and Mortality Weekly Report
- Published
- 2020-08-14
- Volume
- 69
- Issue
- 32
- Pages
- 1081-1088
- ISSN
- 0149-2195 (ISSN-L)
- 1545-861X
- OpenAlex
- W3047978089
- Cited by
- 513
- References
- 8
- FWCI
- 13.37
- Type
- journal article
- Language
- en
- Open access
- diamond
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- Kim, L., Whitaker, M., O’Halloran, A., Kambhampati, A., Chai, S. J., Reingold, A., Armistead, I., Kawasaki, B., Meek, J., Yousey-Hindes, K., Anderson, E. J., Openo, K. P., Weigel, A., Ryan, P., Monroe, M. L., Fox, K., Kim, S., Lynfield, R., Bye, E., . . . Wortham, J. (2020). Hospitalization Rates and Characteristics of Children Aged <18 Years Hospitalized with Laboratory-Confirmed COVID-19 — COVID-NET, 14 States, March 1–July 25, 2020. MMWR. Morbidity and Mortality Weekly Report. https://doi.org/10.15585/mmwr.mm6932e3
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