Cited by 28Heavy Metal Exposure and ToxicityAttention Deficit Hyperactivity DisorderAutism Spectrum Disorder Research

ADHD, lead exposure and prevention: how much lead or how much evidence is needed?

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Nigg, Joel T·2008·Expert Review of Neurotherapeutics

Abstract

Despite its well-documented and much touted high heritability, the environmental causes of attention-deficit/hyperactivity disorder (ADHD) are a growing concern on the US research agenda [1,2]. One...

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  • Organophosphate pesticides, polychlorinated biphenyls, and lead may damage the neural systems implicated in ADHD.

    “In particular, organophosphate pesticides, polychlorinated biphenyls, and lead may damage the neural systems implicated in ADHD (Nigg, 2008; Chang et al., 2018).”

    From A Review of Heterogeneity in Attention Deficit/Hyperactivity Disorder (ADHD) (2019) · cites this paper as Nigg, 2008

    In the main text (page not supplied), Nigg says polychlorinated biphenyls and lead appear to attack neural systems involved in ADHD. The paper mentions pesticides as potentially neurotoxic exposures, but does not identify organophosphate pesticides or make that specific neural-systems claim about them. (LLM, conf=0.86)

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Authors
Nigg, J. T.
Affiliations
Michigan State University (US)
Corresponding author
Nigg, Joel T
Venue
Expert Review of Neurotherapeutics
Published
2008-04
Volume
8
Issue
4
Pages
519-521
ISSN
  • 1473-7175 (ISSN-L)
  • 1744-8360
OpenAlex
W2142239173
Cited by
28
References
18
Citations by year
2025: 1 · 2023: 1 · 2021: 1 · 2020: 3 · 2019: 2 · 2018: 1 · 2017: 2 · 2016: 2 · 2015: 1 · 2014: 2 · 2013: 1 · 2012: 2
FWCI
2.07
Type
journal article
Language
en
Open access
Locations
  • Expert Review of Neurotherapeutics (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Mental Health (R01-MH70004, R01MH070004, R01MH059105)
Topics
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Heavy Metal Exposure and Toxicity
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
Keywords
attention deficit hyperactivity disorder, lead exposure, environmental risk factors, ADHD prevention, heritability
MeSH terms
Attention Deficit Disorder with Hyperactivity, Environmental Exposure, Humans, Risk Factors, Comorbidity, Prevalence, Risk Assessment, Evidence-Based Medicine, Lead Poisoning, Nervous System

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