Cited by 23Reproductive tract infections researchHIV/AIDS Research and InterventionsReproductive Health and Contraception

On the pathway to better birth outcomes? A systematic review of azithromycin and curable sexually transmitted infections.

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Chico, R Matthew, Hack, Berkin B, Newport, Melanie J, Ngulube, Enesia, Chandramohan, Daniel·2013·Expert Review of Anti-infective Therapy

Abstract

The WHO recommends the administration of sulfadoxine-pyrimethamine (SP) to all pregnant women living in areas of moderate (stable) to high malaria transmission during scheduled antenatal visits, beginning in the second trimester and continuing to delivery. Malaria parasites have lost sensitivity to SP in many endemic areas, prompting the investigation of alternatives that include azithromycin-based combination (ABC) therapies. Use of ABC therapies may also confer protection against curable sexually transmitted infections and reproductive tract infections (STIs/RTIs). The magnitude of protection at the population level would depend on the efficacy of the azithromycin-based regimen used and the underlying prevalence of curable STIs/RTIs among pregnant women who receive preventive treatment. This systematic review summarizes the efficacy data of azithromycin against curable STIs/RTIs.

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  1. [67]Martin I Jayaraman G Wong T Liu G Gilmour M Trends in antimicrobial resistance in Neisseria gonorrhoeae isolated in Canada: 2000-2009 Sex. Transm. Dis 38 10 892 898 2011 21934558
  2. [77]Gunter ME Ernest JM McElroy G Azithromycin powder versus erythromycin in the treatment of chlamydial cervicitis in pregnancy Infect. Dis. Obstet. Gynecol 4 53 1996 PMC2364515 18476121
  3. [82]Katz BP FD Orr DP Factors affecting chlamydial persistence or recurrence one and three months after treatment. Chlamydial infections Proceedings of the ninth international symposium on human chlamydial infection Stephens RS Byrne GI Christiansen G et al Eds 35 38 1998
  4. [107]Luntamo M Kulmala T Mbewe B Cheung Y B Maleta K Ashorn P Effect of Repeated Treatment of Pregnant Women with Sulfadoxine-Pyrimethamine and Azithromycin on Preterm Delivery in Malawi: A Randomized Controlled Trial Am. J. Trop. Med. Hyg 83 1212 1220 2010 21118924 PMC2990034
  5. [119]Chico RM Ariti C Cano J Chandramohan D Greenwood B Malaria transmission intensity and the protective effect of intermittent preventive therapy using sulphadoxine-pyrimethamine Evidence Review Group of the World Health Organization 2013
  6. [121]Elliott B Brunham RC Laga M et al Maternal gonococcal infection as a preventable risk factor for low birth weight J. Infect. Dis 161 3 531 536 1990 2313131
  7. [122]Johnson HL Ghanem KG Zenilman JM Erbelding EJ Sexually transmitted infections and adverse pregnancy outcomes among women attending inner city public sexually transmitted diseases clinics Sex. Transm. Dis 38 3 167 171 2011 20852454
  8. [124]Blas MM Canchihuaman FA Alva IE Hawes SE Pregnancy outcomes in women infected with Chlamydia trachomatis: A population-based cohort study in Washington State Sex. Transm. Infect 83 4 314 318 2007 17344249 PMC2598687
  9. [126]Investigators of the Johns Hopkins Study of Cervicitis and Adverse Pregnancy Outcome. Association of Chlamydia trachomatis and Mycoplasma hominis with intrauterine growth retardation and preterm delivery Am. J. Epidemiol 129 1247 1257 1989 2729260
  10. [130]Kiddugavu MG Kiwanuka N Wawer MJ et al Effectiveness of syphilis treatment using azithromycin and/or benzathine penicillin in Rakai, Uganda Sex. Transm. Dis 32 1 1 6 2005 15614114
  11. [131]Hook EW 3rd Stephens J Ennis DM Azithromycin compared with penicillin G benzathine for treatment of incubating syphilis Ann. Int. Med 131 6 434 437 1999 10498560
  12. [132]Riedner G Rusizoka M Todd J et al Single-dose azithromycin versus penicillin G benzathine for the treatment of early syphilis N. Engl. J. Med 353 12 1236 1244 2005 16177249
  13. [143]Khaki P Bhalla P Sharma A Kumar V Correlation between In vitro susceptibility and treatment outcome with azithromycin in gonorrhoea: a prospective study Indian J. Med. Microbiol 25 4 354 357 2007 18087084
  14. [156]Khaki P Bhalla P Sharma P Chawla R Bhalla K Epidemilogical analysis of Neisseria gonorrhoeae isolates by antimicrobial susceptibility testing, auxotyping and serotyping Indian J. Med. Microbiol 225 229 2007 17901639
  15. [193]Somani J Bhullar VB Workowski KA Farshy CE Black CM Multiple drug-resistant Chlamydia trachomatis associated with clinical treatment failure J. Infect. Dis 181 4 1421 1427 2000 10762573

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Authors
Chico, R. M., Hack, B. B., Newport, M. J., Ngulube, E., & Chandramohan, D.
Affiliations
  • London School of Hygiene & Tropical Medicine (GB)
  • Brighton and Sussex Medical School (GB)
Corresponding author
Chico, R Matthew
Venue
Expert Review of Anti-infective Therapy
Published
2013-12
Volume
11
Issue
12
Pages
1303-1332
ISSN
  • 1478-7210 (ISSN-L)
  • 1744-8336
OpenAlex
W1980391945
Cited by
23
References
199
Citations by year
2024: 2 · 2023: 1 · 2021: 2 · 2020: 1 · 2019: 2 · 2017: 1 · 2016: 4 · 2015: 10
FWCI
0.61
Type
journal article
Language
en
Open access
Locations
  • Expert Review of Anti-infective Therapy (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
Funders
Wellcome Trust (100715)
Topics
  • Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
  • Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Health and Contraception
Keywords
azithromycin, reproductive tract infections, sulfadoxine-pyrimethamine, malaria in pregnancy, antenatal prophylaxis, birth outcomes
MeSH terms
Adult, Anti-Bacterial Agents, Clinical Trials as Topic, Drug Combinations, Female, Humans, Male, Pregnancy, Pregnancy Outcome, Pyrimethamine, Sexually Transmitted Diseases, Sulfadoxine, Vaginosis, Bacterial, Malaria, Falciparum, Treatment Outcome, Azithromycin, Drug Resistance, Bacterial, Reproductive Tract Infections

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