Cited by 19Escherichia coli research studiesGut microbiota and healthClostridium difficile and Clostridium perfringens research

The interplay of Escherichia coli O157:H7 and commensal E. coli: the importance of strain-level identification

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Figler, Hillary M., Dudley, Edward G.·2016·Expert Review of Gastroenterology & Hepatology

Abstract

The microbiome and its relationship to human health and disease has become an important topic during the past decade. For example, the gut microbiota has been shown to play a role in diabetes, obes...

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Crossref · 10.1586/17474124.2016.1155449

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  • Intraspecies variation of gut microbiota can substantially change their effect on hosts.

    “There is now ample evidence that intraspecies variation of gut microbiota can substantially change their effect on hosts, first described for enteric pathogens (for example, Escherichia coli 56 ) but more recently demonstrated for immunomodulatory commensals 57,58 , providing further conceptual support for this notion.”

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Research works printed but not linked: 3

  1. Frank C, Werber D, Cramer JP, et al. Epidemic profile of Shiga- toxin-producing Escherichia coli O104: H4outbreak in Germany - preliminary report. N Engl J Med. 2011;365:1771-1780.
  2. Manning SD, Motiwala AS, Springman AC, et al. Variation in viru- lence among clades of Escherichia coli O157: H7associated with disease outbreaks. Proc Natl Acad Sci USA. 2008;105(12):4868- 4873.
  3. Wong CS, Jelacic S, Habeeb RL, et al. The risk of the hemolytic- uremic syndrome after antibiotic treatment of Escherichia coli O157: H7infections. N Engl J Med. 2000;342(26):1930-1936.

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Authors
Figler, H. M., & Dudley, E. G.
Affiliations
Pennsylvania State University (US)
Corresponding author
Dudley, Edward G.
Venue
Expert Review of Gastroenterology & Hepatology
Published
2016-03-07
Volume
10
Issue
4
Pages
415-417
ISSN
  • 1747-4124 (ISSN-L)
  • 1747-4132
OpenAlex
W2289714022
Cited by
19
References
20
Citations by year
2026: 1 · 2025: 2 · 2024: 8 · 2022: 1 · 2021: 3 · 2020: 3 · 2018: 1
Type
journal article
Language
en
Open access
Locations
  • Expert Review of Gastroenterology & Hepatology (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Food and Agriculture (2009-03611)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Escherichia coli research studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Medicine › Infectious Diseases › Clostridium difficile and Clostridium perfringens research
Keywords
Escherichia coli O157:H7, commensal Escherichia coli, strain-level identification, gut microbiota, microbiome, host-microbe interactions, foodborne pathogens
MeSH terms
Gastrointestinal Microbiome, Escherichia coli, Genotype, Humans, Intestines, Phenotype, Virulence, Virulence Factors, Host-Pathogen Interactions, Microbiota

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