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Cited by 180

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

SARS vaccines: where are we?

Open access
Roper, Rachel L, Rehm, Kristina E·2009·Expert Review of Vaccines

Abstract

In this review, the current state of vaccine development against human severe acute respiratory syndrome (SARS) coronavirus, focusing on recently published data is assessed. We discuss which strategies have been assessed immunologically and which have been evaluated in SARS coronavirus challenge models. We discuss inactivated vaccines, virally and bacterially vectored vaccines, recombinant protein and DNA vaccines, as well as the use of attenuated vaccines. Data regarding the correlates of protection, animal models and the available evidence regarding potential vaccine enhancement of SARS disease are discussed. While there is much evidence that various vaccine strategies against SARS are safe and immunogenic, vaccinated animals still display significant disease upon challenge. Current data suggest that intranasal vaccination may be crucial and that new or combination strategies may be required for good protective efficacy against SARS in humans.

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Crossref · 10.1586/erv.09.43

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Metadata

Authors
Roper, R. L., & Rehm, K. E.
Venue
Expert Review of Vaccines
Published
2009-07
Volume
8
Issue
7
Pages
887-898
ISSN
  • 1476-0584 (ISSN-L)
  • 1744-8395
OpenAlex
W2021622102
Cited by
180
References
5
FWCI
2.51
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: SARS vaccines: where are we? https://app.cochat.ai/papers/10.1586/erv.09.43
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Roper, R. L., & Rehm, K. E. (2009). SARS vaccines: where are we? Expert Review of Vaccines. https://doi.org/10.1586/erv.09.43

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.