Evaluation of post-surgical healing in rats using a topical preparation based on extract of Musa sapientum L., Musaceae, epicarp
Open accessAbstract
Considering that oral preparations made with peel green bananas (e.g. flour and extracts) demonstrated healing effects on mucous membranes and skin, this study evaluated the healing and the antimicrobial property of a topical preparation based on extract of Musa sapientum L., Musaceae, (apple banana) in surgically induced wounds in the skin of male Wistar rats, 100 g. The extract was obtained by decoction, the presence of tannins was detected by phytochemical screening and 10% of the extract was incorporated into the carbopol gel (CMS gel). The processes of healing and bacterial isolation were evaluated in the following experimental groups: control (no treatment), treatment with placebo or with the CMS gel. The healing of surgical wounds treated with the CMS gel was faster when compared with the control and placebo groups and the treatment with CMS gel also inhibited the growth of pyogenic bacteria and enterobacteria in the wounds. The results indicate that the extract of Musa sapientum epicarp has healing and antimicrobial properties (in vivo), probably, due to tannins.
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Tannins present in banana peel extract have antimicrobial activity due to their astringent action, with ability to precipitate proteins, which may affect bacterial peptidoglycan.
“The results of Lino et al. [49] found that tannins present in banana peel extract have antimicrobial activity due to their astringent action, with the ability to precipitate proteins, which may affect the bacterial peptidoglycan.”
From Banana Peels: A Waste Treasure for Human Being (2022) · cites this paper as [49]
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- Authors
- Lino, P. B., Corrêa, C. F., Archondo, M. E. D. L., & Dellova, D. C. A. L.
- Affiliations
- Universidade Católica de Santos (BR)
- Universidade de São Paulo (BR)
- Venue
- Revista Brasileira de Farmacognosia
- Published
- 2011-06
- Volume
- 21
- Issue
- 3
- Pages
- 491-496
- ISSN
- 0102-695X (ISSN-L)
- OpenAlex
- W1493331977
- Cited by
- 14
- References
- 19
- Citations by year
- 2025: 2 · 2024: 2 · 2023: 2 · 2022: 4 · 2021: 2 · 2018: 1 · 2017: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc-nd
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- Locations
- Revista Brasileira de Farmacognosia (publishedVersion, cc-by-nc-nd)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (publishedVersion)
- Americanae (AECID Library) (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Health Sciences › Medicine › Rehabilitation › Wound Healing and Treatments
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and biological activity of medicinal plants
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- Musa sapientum, banana peel extract, epicarp, wound healing, topical gel, Carbopol gel, tannins, antimicrobial activity, pyogenic bacteria, Enterobacteriaceae, surgical wounds, herbal medicine
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