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A review of the antimicrobial activity of chitosan
Open accessAbstract
Chitosan, a versatile hydrophilic polysaccharide derived from chitin, has a broad antimicrobial spectrum to which gram-negative, gram-positive bacteria and fungi are highly susceptible. In the current review, three possible and accepted antimicrobial mechanisms for chitosan are presented and briefly discussed. The activity dependence on polymeric molecular weight (MW) and degree of acetylation (DA) are described. The chitosan minimum inhibitory concentrations (MIC) are summarized according to recent data found in the literature. The potential to improve inhibitory growth of bacteria by using water soluble chitosan derivatives is also discussed. The data indicate that the effectiveness of chitosan varies and is dependent on species of target microorganisms.
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Cites
Insights into the mode of action of chitosan as an antibacterial compound.
Raafat, D., von Bargen, K., Haas, A., & Sahl, H.-G. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.00453-08 · Cited by 888
Cited by
Chitosan: A Natural Biopolymer with a Wide and Varied Range of Applications
Jiménez-Gómez, C. P., & Cecilia, J. A. (2020) · Molecules · doi:10.3390/molecules25173981 · Cited by 817
Nam, S., & Mooney, D. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00798 · Cited by 764
Muzzarelli, R. A. A., Boudrant, J., Meyer, D., Manno, N., DeMarchis, M., & Paoletti, M. G. (2012) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2011.09.063 · Cited by 694
Harugade, A., Sherje, A. P., & Pethe, A. (2023) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2023.105634 · Cited by 474
Kou, S. (., Peters, L., & Mucalo, M. (2022) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2022.119132 · Cited by 380
Metadata
- Authors
- Goy, R. C., Britto, D. D., & Assis, O. B. G.
- Venue
- Polímeros
- Publisher
- FapUNIFESP (SciELO)
- Published
- 2009
- Volume
- 19
- Issue
- 3
- Pages
- 241-247
- ISSN
- 0104-1428 (ISSN-L)
- OpenAlex
- W2094399642
- Cited by
- 1,458
- References
- 1
- FWCI
- 5.47
- Type
- journal article
- Language
- en
- Open access
- gold
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- Goy, R. C., Britto, D. D., & Assis, O. B. G. (2009). A review of the antimicrobial activity of chitosan. Polímeros. https://doi.org/10.1590/s0104-14282009000300013
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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