The DOI matches its Crossref record; 88 of the 88 references it cites were found in a registry or an index.
Cerebellum and psychiatric disorders
Open accessAbstract
OBJECTIVE: The objective of this update article is to report structural and functional neuroimaging studies exploring the potential role of cerebellum in the pathophysiology of psychiatric disorders. METHOD: A non-systematic literature review was conducted by means of Medline using the following terms as a parameter: "cerebellum", "cerebellar vermis", "schizophrenia", "bipolar disorder", "depression", "anxiety disorders", "dementia" and "attention deficit hyperactivity disorder". The electronic search was done up to April 2008. DISCUSSION: Structural and functional cerebellar abnormalities have been reported in many psychiatric disorders, namely schizophrenia, bipolar disorder, major depressive disorder, anxiety disorders, dementia and attention deficit hyperactivity disorder. Structural magnetic resonance imaging studies have reported smaller total cerebellar and vermal volumes in schizophrenia, mood disorders and attention deficit hyperactivity disorder. Functional magnetic resonance imaging studies using cognitive paradigms have shown alterations in cerebellar activity in schizophrenia, anxiety disorders and attention deficit hyperactivity disorder. In dementia, the cerebellum is affected in later stages of the disease. CONCLUSION: Contrasting with early theories, cerebellum appears to play a major role in different brain functions other than balance and motor control, including emotional regulation and cognition. Future studies are clearly needed to further elucidate the role of cerebellum in both normal and pathological behavior, mood regulation, and cognitive functioning.
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“Due to localized effects at DAT sites corresponding to the action of stimulants (Ciliax et al., 1999; Schou et al., 2005), abnormalities of the anterior cingulate cortex (ACC) and supplementary motor area (SMA) regions were normalized along with improved capacity of self-regulatory control (Baldaçara, Borgio, De Lacerda, & Jackowski, 2008; Fan, McCandliss, Fossella, Flombaum, & Posner, 2005; Posn”
From Overlapping and differential neuropharmacological mechanisms of stimulants and nonstimulants for attention-deficit/hyperactivity disorder: A comparative neuroimaging analysis (2024) · cites this paper as Baldaçara, Borgio, De Lacerda, & Jackowski, 2008
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Cites
Castellanos, F. X. (2002) · JAMA · doi:10.1001/jama.288.14.1740 · Cited by 1,646
Schmahmann, J. D. (2004) · Journal of Neuropsychiatry · doi:10.1176/jnp.16.3.367 · Cited by 1,493
Anatomical evidence for cerebellar and basal ganglia involvement in higher cognitive function
Middleton, F. A., & Strick, P. L. (1994) · Science · doi:10.1126/science.7939688 · Cited by 1,356
Meta-analysis of structural imaging findings in attention-deficit/hyperactivity disorder
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The anatomy of mood disorders—review of structural neuroimaging studies
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Neuroanatomical correlates of happiness, sadness, and disgust
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The neuropsychiatry of the cerebellum — insights from the clinic
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Research works printed but not linked: 4
- Konarski JZ, 2006, Is the cerebellum relevant in the circuitry of neuropsychiatric disorders?, J Psychiatry Neurosci, 30, 178
- Razzouk D, 2006, How do experts recognize schizophrenia: the role of disorganization symptom, Rev Bras Psiquiatr, 28, 5, 10.1590/S1516-44462006000100003 · DOI
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Annual research review: enduring neurobiological effects of childhood abuse and neglect
Teicher, M. H., & Samson, J. A. (2016) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12507 · Cited by 1,473
Multivariate classification of social anxiety disorder using whole brain functional connectivity
Liu, F., Guo, W., Fouché, J., Wang, Y., Wang, W., Ding, J., Zeng, L., Qiu, C., Gong, Q., Zhang, W., et al. (2013) · Brain Structure and Function · doi:10.1007/s00429-013-0641-4 · Cited by 349
The Cerebellum and Psychiatric Disorders
Phillips, J. R., Hewedi, D. H., Eissa, A. M., & Moustafa, A. A. (2015) · Frontiers in Public Health · doi:10.3389/fpubh.2015.00066 · Cited by 357
Su, L., Cai, Y., Xu, Y., Dutt, A., Shi, S., & Bramon, E. (2014) · BMC Psychiatry · doi:10.1186/s12888-014-0321-9 · Cited by 230
Dichter, G. S., Kozink, R. V., McClernon, F. J., & Smoski, M. J. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.09.048 · Cited by 170
Metadata
- Authors
- Baldaçara, L., Borgio, J. G. F., Lacerda, A. L. T. D., & Jackowski, A. P.
- Affiliations
- Universidade Federal do Tocantins (BR)
- Universidade Federal de São Paulo (BR)
- ORCID
- Venue
- Revista Brasileira de Psiquiatria
- Publisher
- EDITORA SCIENTIFIC
- Published
- 2008-09
- Volume
- 30
- Issue
- 3
- Pages
- 281-289
- ISSN
- 1516-4446 (ISSN-L)
- OpenAlex
- W2068886208
- Cited by
- 183
- References
- 87
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 8 · 2023: 19 · 2022: 10 · 2021: 11 · 2020: 10 · 2019: 8 · 2018: 6 · 2017: 10 · 2016: 8 · 2015: 12 · 2014: 17 · 2013: 11 · 2012: 11
- FWCI
- 6.75
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc
- Locations
- Brazilian Journal of Psychiatry (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- Americanae (AECID Library) (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Keywords
- cerebellum, cerebellar vermis, mental illness, schizophrenia, bipolar disorder, major depressive disorder, anxiety disorders, dementia, attention deficit hyperactivity disorder, cerebellar volume, cerebellar activity, emotion regulation, cognition, mood regulation
- MeSH terms
- Anxiety Disorders, Attention Deficit Disorder with Hyperactivity, Mental Disorders, Cerebellum, Dementia, Humans, Magnetic Resonance Imaging, Schizophrenia, Mood Disorders
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